Skip to main content
Elsevier

Correlative Light and Electron Microscopy VI

  • 1st Edition, Volume 213 - February 1, 2027
  • Latest edition
  • Editors: Lorenzo Galluzzi, Thomas Müller-Reichert, Paul Verkade
  • Language: English

Correlative Light and Electron Microscopy VI presents current methods and applications in combining light microscopy and electron microscopy to study biological structures and pr… Read more

Back to School

Start strong. Study with purpose.

Save up to 25% on trusted learning resources

Shop now

Description

Correlative Light and Electron Microscopy VI presents current methods and applications in combining light microscopy and electron microscopy to study biological structures and processes with high spatial and temporal resolution. The volume highlights practical approaches for linking dynamic imaging with ultrastructural analysis, enabling researchers to investigate cells, tissues, and subcellular components in greater detail. Covering both established and emerging techniques, this book serves as a useful resource for scientists working in cell biology, structural biology, imaging, and related biomedical fields.

Key features

  • Presents advanced methodologies in correlative light and electron microscopy for studying cellular and subcellular structure
  • Covers practical protocols and experimental approaches for integrating light microscopy with electron microscopy
  • Highlights applications across cell biology, structural biology, neuroscience, and biomedical research

Readership

university research libraries, biomedical research institutes, life science researchers, cell biologists, molecular biologists, microscopists

Table of contents

1. A novel slicing device to facilitate targeting multiple positions in a block face
Christel Genoud, Alexandra Schmitt and Jean Daraspe

2. EMcapsulins as versatile markers for Correlative Microscopy.
Gil Gregor Westmeyer and Oleksandr Berezin

3. Improved targeting for cryo CLEM by prescreening
Paul Verkade

4. Correlative Cryo-soft X-ray.
Anna Sartori

5. Correlative Imaging Software
Paul Verkade

6. Correlative Light and Electron Microscopy with Immersion Objectives.
Thomas P. Burg

7. Cryo-Correlative Light and Electron Microscopy of Bulky Tissues: Three-Dimensional Imaging of Embryonic Bone Vasculature
Emeline Raguin, Nikolai Rosenthal, Chloe Jones and Anne Seewald

8. Development of sample analysis pipeline for EM, STED, and SIMS
Thi Ngoc Nhu Phan

9. Correlative Advanced Environmental Microscopy
Neděla Vilem

10. Spin mill CLEM
Paul Verkade

11. A correlative light and electron microscopy workflow for nanoscale GLUT4 localization in adult cardiomyocytes
Paul Verkade, Lorna Hodgson, Kaspar W Persson, Chris Neal, Samantha Gallero, Carlos Henriquez-Olguin, Judith Mantell and Thomas E. Jensen

12. Correlative volume EM of rat salivary gland mitochondria imaged by intravital label-free live 2P microscopy.
Kedar Narayan

13. Streamlining Cell Preparation and Fiducial-Free Registration for 3D Correlative Light and Electron Microscopy
Andreas Walter

14. AI-based toolkits for quantitative electron microscopy
Robert Kiewisz and Thomas Müller-Reichert

Product details

  • Edition: 1
  • Latest edition
  • Volume: 213
  • Published: February 1, 2027
  • Language: English

About the editors

LG

Lorenzo Galluzzi

Lorenzo Galluzzi is Assistant Professor of Cell Biology in Radiation Oncology at the Department of Radiation Oncology of the Weill Cornell Medical College, Honorary Assistant Professor Adjunct with the Department of Dermatology of the Yale School of Medicine, Honorary Associate Professor with the Faculty of Medicine of the University of Paris, and Faculty Member with the Graduate School of Biomedical Sciences and Biotechnology of the University of Ferrara, the Graduate School of Pharmacological Sciences of the University of Padova, and the Graduate School of Network Oncology and Precision Medicine of the University of Rome “La Sapienza”. Moreover, he is Associate Director of the European Academy for Tumor Immunology and Founding Member of the European Research Institute for Integrated Cellular Pathology. Galluzzi is best known for major experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology. He has published over 450 articles in international peer-reviewed journals and is the Editor-in-Chief of four journals: OncoImmunology (which he co-founded in 2011), International Review of Cell and Molecular Biology, Methods in Cell biology, and Molecular and Cellular Oncology (which he co-founded in 2013). Additionally, he serves as Founding Editor for Microbial Cell and Cell Stress, and Associate Editor for Cell Death and Disease, Pharmacological Research and iScience.
Affiliations and expertise
Assistant Professor of Cell Biology in Radiation Oncology, Department of Radiation Oncology, Weill Cornell Medical College, NY, USA

TM

Thomas Müller-Reichert

Thomas Müller-Reichert works in the Core Facility Cellular Imaging (CFCI), Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Germany.
Affiliations and expertise
Core Facility Cellular Imaging (CFCI), Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Germany

PV

Paul Verkade

Paul Verkade is a Professor of Bioimaging at the University of Bristol, UK where his research group works on the development and application of microscopy techniques to Biomedical questions. The main tools in the lab are Electron microscopy (EM) and Correlative Light Electron Microscopy (CLEM) in which fields he has published over 100 papers and edited 5 books on CLEM (including 4 Volumes of the Methods in Cell Biology series). PV obtained his PhD at the University of Utrecht, The Netherlands in 1996. Subsequently he did a post-doc at the EMBL, Heidelberg, Germany, after which he set up the electron microscopy unit at the newly formed Max Planck Institute for Molecular Cell Biology in Dresden, Germany from 2001. He moved to the UK in 2006 to set up another EM unit as part of an integrated LM and EM bioimaging facility, which facilitates CLEM workflows. He is actively involved in shaping the future microscopy landscape with roles in the Royal Microscopical Society and BioimagingUK and a current focus on putting volumeEM on the imaging map through community building and the organisation and co-chairing of the 1st Gordon Research Conference on vEM.
Affiliations and expertise
The University of Bristol, Bristol, UK