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Books in Life sciences

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  • Cellular Senescence and Aging

    • 1st Edition
    • Volume 181
    • English
    Cellular Senescence and Aging, Volume 181 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as assessing polyglutamine tract aggregation in the nematode Caenorhabditis elegans, Generation of glial cell-derived neurotrophic factor (gdnf) morphants in zebrafish larvae by cerebroventricular microinjection of vivo morpholino, Methods for detection of mitochondrial reactive oxygen species in senescent cells, Assessment of cell cycle progression and mitotic slippage by videomicroscopy, The original colorimetric method to detect cellular senescence, and more.Additional sections cover Assessing microbiota composition in the context of aging, Assessing chronological aging in Saccharomyces cerevisiae, Image processing and supervised machine learning for retinal microglia characterization in senescence, Measuring telomerase activity using TRAP assays, High throughput assessment of cellular senescence, Detection of radiation-induced senescence by the Debacq-Chainiaux protocol: Improvements and upgrade in the detection of positive events, Dynamic and scalable assessment of the senescence-associate... secretory phenotype (SASP), Flow cytometry-assisted quantification of cell cycle arrest in cancer cells treated with CDK4/6 inhibitors, and more.

  • Advances in Protein Chemistry and Structural Biology

    • 1st Edition
    • Volume 138
    • English
    Advances in Protein Chemistry and Structural Biology, Volume 138 covers reviews of methodology and research in all aspects of protein chemistry, including purification/express... proteomics, modeling and structural determination and design. Chapters in this release include Proteomic Applications in Identifying Protein-Protein Interactions, Understanding functions of eEF1 translation elongation factors beyond translation. A proteomic approach, Proteomics provides insights into theranostic potential of extracellular vesicles, Towards a shareable functional analysis of the structural proteome, Functional unfoldomics, In-silico Network Pharmacology Study on Glycyrrhiza glabra: Analyzing the Immune-Boosting phytochemical properties of Siddha Medicinal Plant against COVID-19, and more.Other chapters cover In silico Network Pharmacology Analysis and Molecular Docking Validation of Swasa Kudori for Screening Druggable Phytoconstituents of Asthma, Proteomics and Genomics Insights on Malignant Osteosarcoma, Application of functional proteomics in understanding RNA Virus-Mediated Infection, Biofilm proteome of Staphylococcus aureus: implications for therapeutic interventions to biofilm-associated infections, A computational pipeline elucidating functions of conserved hypothetical Trypanosoma cruzi proteins based on public proteomic data, Functional Proteomics based on Protein Microarray Technology for Biomedical Research, and an Analysis of endoglucanases production using proteomics and metatranscriptomics.

  • Nanomedicine in Cancer Immunotherapy

    • 1st Edition
    • Prashant Kesharwani
    • English
    Nanomedicine in Cancer Immunotherapy bridges the two disciplines of nanotechnology and immunology, summarizing the latest research into novel cancer treatments, often personalized to the patient. The book covers a wide range of nanomaterial types for use in cancer immunotherapy, including hydrogel, lipid, exosome, gold and peptide nanoparticles. The preparation, application, pros and cons of each nanomaterial class is reviewed, helping the reader understand the potential for each to tailor their own selections. Nanovaccines are also covered, along with a clinical evaluation and market analysis of nanomedicines for immunotherapy, offering an important clinical and commercial overview of this rapidly developing field.This book is an interesting reference for those working in the fields of nanotechnology, immunology, and cancer therapeutics, as well as clinicians with an interest in novel nano-based cancer treatments.

  • Targeting Angiogenesis, Inflammation and Oxidative Stress in Chronic Diseases

    Angiogenesis, Inflammation and Oxidative Stress in Chronic Diseases
    • 1st Edition
    • Tapan Behl + 2 more
    • English
    Targeting Angiogenesis, Inflammation and Oxidative Stress in Chronic Diseases presents recent advances in the vivid molecular pathways targeting angiogenesis, inflammation, and oxidative stress that contribute very widely to the genesis of chronic diseases. The books highlights drugs from natural and synthetic origins in the management/preventio... of diseases, along with the drug delivery approaches. The book’s authors from various key institutions around the globe deliver well-structured and designed chapters. The systematic presented information and knowledge will surely aid consistency and continuity. The multifaceted book is enriched with deep scientific content. Each chapter clearly defines the facts, the emerging role of molecular pathways, and targets and focus, along with key challenges and future directions that will provide new areas for researchers to explore new targets in the domain.

  • Molecular Biology of B Cells

    • 3rd Edition
    • Tasuku Honjo + 4 more
    • English
    Molecular Biology of B Cells, Third Edition provides a comprehensive reference on how B cells are generated, selected, activated, and engaged in antibody production. These developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. The book offers an integrated view of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. This new edition provides updated research on B cell development and function, the use of therapeutic antibodies in cancer and infectious disease, and more. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, this updated release is a definitive resource, vital for researchers across molecular biology, immunology, and genetics.

  • The Potential of Microbes for a Circular Economy

    • 1st Edition
    • E.K. Radhakrishnan + 2 more
    • English
    The Potential of Microbes for a Circular Economy provides an understanding of the role of microbes in a circular economy (CE). The book covers the development of effective bio-based formulations for field applications and describes the basic principles and applications, the important role of microorganisms, and new insights into a sustainable ecosystem for the circular economy. In addition, it compiles the latest advancement in the field of CE by covering microbes and microbial products, thus providing microbiologists the tools to engage with the public, policymakers, and industry to inform the debate on addressing current challenges.

  • Continental Northeast Asian Amphibians

    Origins, Behavioural Ecology, and Conservation
    • 1st Edition
    • Amaël Borzée
    • English
    Continental Northeast Asian Amphibians: Origins, Behavioral Ecology, and Conservation is the only comprehensive compilation of knowledge on the amphibian species of continental northeast Asia. Along with accounts for each species, the book introduces the biogeographic history, behavioral patterns, ecological requirements, and threats in the region. Written by a leading expert on Asian amphibians, this book delves into the details of origin and life history and distinguishes which variables have been instrumental to the distribution of populations and amphibian biodiversity in this region. Sections provide detailed accounts for field identification and range of the species’ behavior during both breeding and non-breeding seasons.Finally, the book provides in-depth accounts on the threats and trends for each species, considering the current conservation pressure in the region. Each point is explained in relation with the very contrasted landscapes of the region that include two rather different species assemblages, one on the alluvial plains and the other at higher elevation on mountain ranges.

  • Aminoff's Diagnosis of Neuromuscular Disorders

    • 4th Edition
    • Michael J. Aminoff + 2 more
    • English
    **Selected for 2025 Doody’s Core Titles® in Neurology**Succinct yet comprehensive, Aminoff's Diagnosis of Neuromuscular Disorders, 4th Edition, provides expert information and guidance on the clinical, electrodiagnostic, and imaging aspects of neuromuscular disorders. Fully updated, it reflects important advances in the field, including an improved understanding of the molecular and genetic basis of neuromuscular disease, an expanded use of next-generation genetic testing, refinements in electrodiagnosis, and the use of ultrasound imaging techniques to evaluate the peripheral nervous system. In-depth discussions of disease states, as well as the evidence supporting the use of electrodiagnostic and imaging techniques, moves this reference from simply answering the question “How?” to also answering “Why?”

  • Infection and Autoimmunity

    • 3rd Edition
    • Naim Mahroum + 2 more
    • English
    In 2020 we lost Noel Rose, co-editor of the classic Infection and Autoimmunity. To honor and respect his work, a group of experts in the field have taken the initiative to make this book perpetual. The third edition of Infection and Autoimmunity updates all the recent and leading papers on infection and autoimmunity, in addition to a dedicated section on to the correlation between SARS-CoV-2 infection and autoimmunity. From the very beginning of the COVID-19 pandemic, numerous papers have been published, including studies conducted by the editors and authors of the book, on COVID-19 and autoimmunity, and therefore this knowledge has been incorporated into this new edition. The addition and extended coverage on SARS-CoV-2/COVID-19 and autoimmunity are pivotal for the third edition of the book due to the COVID-19 pandemic. Medical students and practitioners, as well as academic staff in medical schools globally, are enthusiastic in searching for better understanding of the correlation between infection and autoimmunity in general, and the long-term effects of SARS-CoV-2 and COVID-19 on the immunce system in particular, especially in terms of autoimmunity related to the virus.

  • Natural Molecules in Neuroprotection and Neurotoxicity

    • 1st Edition
    • Marcos Roberto de Oliveira
    • English
    Natural Molecules in Neuroprotection and Neurotoxicity brings together research in the area of natural compounds and their dual effects of neuroprotection and neurotoxicity when interacting with brain cells. This two volume set is organized into four sections that address molecular mechanism underlying neuroprotection and neurotoxicity, neuroprotection mediated by natural molecules, neurotoxicity induced by natural compounds and nanotechnology-relat... strategies utilized in neuroprotection.Writ... by well-known researchers all over the world, chapters provide an in-depth analysis of numerous molecules, such as algae, plant and fungus-derived molecules, and comprehensively discuss their mechanisms of action and possible clinical applications. This set provides an essential reference for researchers and clinical scientists interested in the effects of natural compounds on the human health and disease.

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