Progress in Chemical Toxicology

Contents

Isolation and Separation Techniques for Identification of Poisons

I. Acetone Extraction of Organic Substances

II. Separation of Alkaloids from Tissue

III. Two-Stage Extraction

References

Application of Gas Chromatography to Toxicology

I. Introduction

II. Columns

III. Detectors

IV. Carrier Gas

V. Sample

VI. Chromatogram Records

VII. Basic Theory

VIII. Analytical Procedures

References

Aliphatic Alcohols

I. Introduction

II. "Endogenous" Alcohol

III. Absorption of Alcohol

IV. Distribution of Absorbed Alcohol

V. Fate of Body Alcohol

VI. Pharmacological and Toxicological Effects

VII. Abnormal Changes in Alcohol Level

VIII. Medicolegal Interpretation of Blood Alcohol Level

IX. Analytical Methods for Body Alcohol

X. Investigations of the Accuracy of Analytical Methods

XI. Other Aliphatic Alcohols

References

Acidic and Neutral Poisons

I. Introduction

II. Isolation Procedures

III. Purification Procedures

IV. Identification

V. Analyses for Specific Poisons

VI. General Toxicology

VII. Conclusions

References

Ataraxics and Nonbarbiturate Sedatives

I. Introduction

II. Derivatives of Phenothiazine

III. d-Propoxyphene

IV. Chlordiazepoxide

V. Glutethimide

VI. Hydroxyzine

VII. Methapyrilene

VIII. Ethchlorvynol

IX. Methyprylon

X. Ethinamate

XI. Phenaglycodol

XII. Captodiamine

XIII. Imipramine

References

The Determination of Antiarthritics, Antihistamines, and Thymoleptics

I. Antiarthritics

II. Antihistamines

III. Thymoleptics

References

Narcotics and Related Bases

I. General Introduction

II. Literature Review

III. Physicochemical Methods for the Identification of Narcotics and Related Bases

IV. Opium—Assay, Characteristics, Composition, and Origin

V. Cannabis (Marijuana)

References

Toxicity of Air Pollutants

I. Introduction

II. Photochemical Smog

III. Effects of Photochemical Smog

IV. Toxicity of Air Pollutants

References

Analytical Methods for Air Pollutants

I. Introduction

II. Analysis of Pollutants Which May Have a Direct Toxic Effect if Present in the Atmosphere in Sufficient Concentration for a Sufficient Period of Time

III. Analysis of Pollutants Which May Not Be Present in the Atmosphere in Sufficient Concentration to Cause Toxicity but Which May Create Nuisance Problems Due to Odor

IV. Analysis of Pollutants Involved in the Photochemical Process

V. Continuous Automatic Measurement of Air Contaminants

References

Poisonous Mushrooms

I. Introduction

II. Chemistry and Methods of Detection of Mushroom Poisons

III. Symptoms and Treatment of Mushroom Poisoning

IV. Names, Descriptions, and Relative Toxicities of Poisonous Mushrooms

References

Poisonous Seeds and Fruits

I. Introduction

II. Definitions and Distinctions

III. Toxic Components

IV. Toxic Fruits and Seeds

References

Author Index

Subject Index