International Review of Connective Tissue Research

Contributors

Preface

Contents of Previous Volumes

The Structure of Collagen Genes

I. Introduction

II. Characterization of Collagen Genes

III. Fibrillar Collagen Genes

IV. Nonfibrillar Invertebrate Collagen Genes

V. Some Speculations on Collagen Gene Structure

References

Elastin Gene Expression

I. Introduction

II. Isolation of Elastin mRNAs

III. Cell-Free Translation of Elastin mRNAs

IV. Identification of Tropoelastin

V. Tropoelastin Synthesis in Organ Culture

VI. The Signal Peptide of Tropoelastin b

VII. Distribution of Tropoelastins a and b

VIII. Differential Expression of Tropoelastins a and b during Development

IX. Effect of Glucocorticoids on Elastin Synthesis

X. Synthesis and Cloning of Elastin cDNA

XI. Conclusion

References

Elastin-Associated Microfibrils and Microfibrillar Proteins

I. Introduction and Historical Overview

II. Nomenclature

III. Elastin-Associated Microfibrils in Normal Tissues

IV. Oxytalan, Elaunin, and Elastin-Associated Microfibrils

V. Elastin-Associated Microfibrils in Disease

VI. Microfibrils in Nonelastic Tissues

VII. Concluding Remarks

References

Periodontal Ligament

I. Introduction

II. Cells

III. Fibers in the Periodontal Ligament

IV. Periodontal Ligament Collagen

V. Noncollagenous Components of Periodontal Ligament

VI. Glycosaminoglycans/Proteoglycans

VII. Glycoproteins

VIII. Periodontal Ligament Fibroblasts

IX. Concluding Remarks

References

Lung Connective Tissue

I. Introduction

II. General Considerations

III. Lung Connective Tissues

IV. Remodeling of Lung Connective Tissue

V. Concluding Remarks

References

Liver Fibrosis

I. Introduction

II. Connective Tissue of the Normal Liver

III. Liver Fibrosis

IV. Outlook for Treatment

References

Connective Tissue Changes in Cancer

I. Introduction

II. The Etiology of Stromal Involvement

III. Morphology of Stromal Changes

IV. Quantitative Studies on Collagen during Carcinogenesis

V. Lytic Enzymes in Cancer

VI. Elastin during Carcinogenesis

VII. Fibronectin in Cancer

VIII. Stromal Glycosaminoglycans in Cancer

IX. Stromal Mast Cells in Cancer

X. Stromal Changes Associated with Vascular Proliferation

XI. Phenomena at the Epithelial-Stromal Junction

XII. Transplantation Experiments

XIII. Data on Tumors of Mesenchymal Origin

XIV. Concluding Remarks

References

Index