International Review of Connective Tissue Research

Volume 10

1st Edition - October 1, 1983

Editors: David A. Hall, D. S. Jackson

eBook ISBN:

9 7 8 - 1 - 4 8 3 1 - 9 1 7 2 - 0

International Review of Connective Tissue Research is a compilation of scientific research mainly focuses on developments in special tissues. A detailed discussion of the lung and… Read more

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International Review of Connective Tissue Research is a compilation of scientific research mainly focuses on developments in special tissues. A detailed discussion of the lung and liver is included. Another topic of interest is the liver fibrosis development induced by parasitic infection or alcohol. The periodontal ligament is specialized tissue whose basic role is tooth support. This tissue is covered in detail. A section of the book provides an analysis of the elastin gene expression and regulation. Topics such as the microfibrillar components of connective tissue, the regulation of collagen genes, the complexity and the evolution of the collagen molecule, the invasiveness of malignant tumors, and the characteristics of fibroblast are fully explained. The text presents an exhaustive description of the connective tissue of the lung. This chapter includes a comprehensive description of the pulmonary system. The book will provide useful information to doctors, students, researchers and specialists in the field of human anatomy.

Contributors

Preface

Contents of Previous Volumes

The Structure of Collagen Genes

I. Introduction

II. Characterization of Collagen Genes

III. Fibrillar Collagen Genes

IV. Nonfibrillar Invertebrate Collagen Genes

V. Some Speculations on Collagen Gene Structure

References

Elastin Gene Expression

I. Introduction

II. Isolation of Elastin mRNAs

III. Cell-Free Translation of Elastin mRNAs

IV. Identification of Tropoelastin

V. Tropoelastin Synthesis in Organ Culture

VI. The Signal Peptide of Tropoelastin b

VII. Distribution of Tropoelastins a and b

VIII. Differential Expression of Tropoelastins a and b during Development

IX. Effect of Glucocorticoids on Elastin Synthesis

X. Synthesis and Cloning of Elastin cDNA

XI. Conclusion

References

Elastin-Associated Microfibrils and Microfibrillar Proteins

I. Introduction and Historical Overview

II. Nomenclature

III. Elastin-Associated Microfibrils in Normal Tissues

IV. Oxytalan, Elaunin, and Elastin-Associated Microfibrils

V. Elastin-Associated Microfibrils in Disease

VI. Microfibrils in Nonelastic Tissues

VII. Concluding Remarks

References

Periodontal Ligament

I. Introduction

II. Cells

III. Fibers in the Periodontal Ligament

IV. Periodontal Ligament Collagen

V. Noncollagenous Components of Periodontal Ligament

VI. Glycosaminoglycans/Proteoglycans

VII. Glycoproteins

VIII. Periodontal Ligament Fibroblasts

IX. Concluding Remarks

References

Lung Connective Tissue

I. Introduction

II. General Considerations

III. Lung Connective Tissues

IV. Remodeling of Lung Connective Tissue

V. Concluding Remarks

References

Liver Fibrosis

I. Introduction

II. Connective Tissue of the Normal Liver

III. Liver Fibrosis

IV. Outlook for Treatment

References

Connective Tissue Changes in Cancer

I. Introduction

II. The Etiology of Stromal Involvement

III. Morphology of Stromal Changes

IV. Quantitative Studies on Collagen during Carcinogenesis

V. Lytic Enzymes in Cancer

VI. Elastin during Carcinogenesis

VII. Fibronectin in Cancer

VIII. Stromal Glycosaminoglycans in Cancer

IX. Stromal Mast Cells in Cancer

X. Stromal Changes Associated with Vascular Proliferation

XI. Phenomena at the Epithelial-Stromal Junction

XII. Transplantation Experiments

XIII. Data on Tumors of Mesenchymal Origin

XIV. Concluding Remarks

References

Index