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Elsevier

Books in Life sciences

  • The immune system

    • 1st Edition
    • Rodney Langman
    • English
    9780124365858 The Immune System: Evolutionary Principle Guide our Understanding of this Complex Biological Defense System provides the conceptual framework of immunology and the evolutionary events that have shaped the understanding of the immune system. This book contains 10 chapters, and begins with a brief discussion on the evolutionary aspects of immunology considering the Darwinian principles of evolution. This topic is followed by a presentation of the selective pressures that are likely to have molded the immune system, as well as the laws of the immune system and their corollaries concerning host defense mechanism. The subsequent chapters are devoted to cellular components of the immune system, including the B and T cells, immunoglobulins, interleukins, major histocompatibility complex, and lymphoid organs. The structural information and the evolutionary events in these immune system components are provided. A chapter focuses on the evolutionary successful components of the inflammatory system. The concluding chapter deals with the conflicting conventional wisdoms on functional immune system. This book will prove useful to immunologists and research workers in immunology and related fields.

  • Myopathies, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 32-3
    • Mazen Dimachkie
    • English
    Congential myopathies, Muscular dystropies, Glycogen storage diseases of muscle, and Idiopathic and Inflammatory myopathies are presented in this volume of Neurologic Clinics. Topics include: Muscle channelopathies; Pompe disease; Congenital myopathies and muscular dystrophies; Duchenne and Becker muscular dystrophies; Distal myopathies; Limb-girdle muscular dystrophy; Fascioscapulomuneral muscular dystrophy; Myotonic dystrophy; Metabolic and mitochondrial myopathies; Sporadic inclusion body myositis; Toxic myopathies; Idiopathic Inflammatory myopathies; Approach to muscle disease.

  • Arthropoda Part B

    • 1st Edition
    • Marcel Florkin
    • English
    Chemical Zoology, Volume VI, Arthropoda Part B, provides zoologists and chemists with an overview of the state of knowledge in chemistry and zoology and an introduction to the existing literature. The treatise is arranged by phyla, an arrangement which seemed most suitable for presenting chemical information of zoological significance and for bringing to the attention of chemists those aspects of biochemical diversity of greatest potential interest. Each section, dealing with a major phylum, is introduced by a discussion of the biology and systematics of the group. This is followed by chapters dealing with various aspects of the biochemistry of the group. This volume contains 11 chapters that discuss the integument, hemolymph, blood respiratory pigments, hemolymph coagulation excretion, pigments, chemistry, toxicology, and pharmacology of Arthropoda. The respiration, energy metabolism, and chemical ecology of Crustacea as well as the oxidative metabolism of Insecta are also covered.

  • Aves

    • 1st Edition
    • Alan H. Brush
    • English

  • Hyaluronan Signaling and Turnover

    • 1st Edition
    • Volume 123
    • Melanie Simpson + 1 more
    • English
    Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. This volume covers hyaluronan signaling and turnover.

  • Regulated Cell Death Part B

    Necroptotic, Autophagic and other Non-apoptotic Mechanisms
    • 1st Edition
    • Volume 545
    • English
    Regulated Cell Death Part A & Part B of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in apoptosis focusing on the important areas of intrinsic pathway, extrinsic pathway, caspases, cellular assays and post-apoptotic effects and model organisms; as well as topics on necroptosis and screening approaches.

  • Modern Concepts of Focal Epileptic Networks

    • 1st Edition
    • Volume 114
    • English
    This volume of International Review of Neurobiology concentrates on modern concepts of focal epileptic networks. The volume addresses specific topics such as seizures (including transition and termination), limbic networks, alteration of metabolism, and neocortical focus and malformation of cortical development, among others. Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews, and thematic volumes that focus on recent progress in a specific area of neurobiology research.

  • Mechanotransduction

    • 1st Edition
    • Volume 126
    • English
    Progress in Molecular Biology and Translational Science provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references. Volume 126 features in-depth reviews that focus on the tools required to investigate mechanotransduction. Additional chapters focus on how we can use these tools to answer fundamental questions about the interaction of physical forces with cell biology, morphogenesis, and function of mature structures. Chapters in the volume are authored by a unique combination of cell biologists and engineers, providing a range of perspectives on mechanotransduction.

  • Molecular Genetics of Sex Determination

    • 1st Edition
    • Stephen S. Wachtel
    • English
    In this era of accelerated discovery and prolific output, Molecular Genetics of Sex Determination keeps readers abreast of this fields fast-moving biology. Its chapters were completed by experts in eacharea only months before publication. The text is organized into two parts. First, it reviews the basic biology of sex determination and summarizes ground-breaking work in mouse, marsupial, and Drosophila systems. Second, it covers current human genetics, clinical studies, and the syndromes of abnormal sex differentiation. With chapters by preeminent reproductive biologists, this is a capital work. Ohno's law is described by Ohno; the Lyon hypothesis, by Lyon; Sinclair tells how he cloned the testis-determining gene; and so on. Molecular Genetics of Sex Determination is authoritative, comprehensive, and current. It is prime reading for geneticists, developmental biologists, graduate students in these and related fields, clinical researchers, physicians, and medical students.

  • Encyclopedia of Meat Sciences

    • 2nd Edition
    • Carrick Devine + 1 more
    • English
    The Encyclopedia of Meat Sciences, Second Edition, Three Volume Set prepared by an international team of experts, is a reference work that covers all important aspects of meat science from stable to table. Its topics range from muscle physiology, biochemistry (including post mortem biochemistry), and processing procedures to the processes of tenderization and flavor development, various processed meat products, animal production, microbiology and food safety, and carcass composition. It also considers animal welfare, animal genetics, genomics, consumer issues, ethnic meat products, nutrition, the history of each species, cooking procedures, human health and nutrition, and waste management. Fully up-to-date, this important reference work provides an invaluable source of information for both researchers and professional food scientists. It appeals to all those wanting a one-stop guide to the meat sciences.

  • Textbook of Veterinary Physiological Chemistry

    • 3rd Edition
    • Larry Engelking
    • English
    Bridging the gap between basic and clinical science concepts, the Textbook of Veterinary Physiological Chemistry, Third Edition offers broad coverage of biochemical principles for students and practitioners of veterinary medicine. The only recent biochemistry book written specifically for the veterinary field, this text covers cellular-level concepts related to whole-body physiologic processes in a reader-friendly, approachable manner. Each chapter is written in a succinct and concise style that includes an overview summary section, numerous illustrations for best comprehension of the subject matter, targeted learning objectives, and end of the chapter study questions to assess understanding. With new illustrations and an instructor website with updated PowerPoint images, the Textbook of Veterinary Physiological Chemistry, Third Edition, proves useful to students and lecturers from diverse educational backgrounds. Sectional exams and case studies, new to this edition, extend the breadth and depth of learning resources.

  • Bone Substitute Biomaterials

    • 1st Edition
    • K. Mallick
    • English
    Bone substitute biomaterials are fundamental to the biomedical sector, and have recently benefitted from extensive research and technological advances aimed at minimizing failure rates and reducing the need for further surgery. This book reviews these developments, with a particular focus on the desirable properties for bone substitute materials and their potential to encourage bone repair and regeneration. Part I covers the principles of bone substitute biomaterials for medical applications. One chapter reviews the quantification of bone mechanics at the whole-bone, micro-scale, and non-scale levels, while others discuss biomineralization, osteoductivization, materials to fill bone defects, and bioresorbable materials. Part II focuses on biomaterials as scaffolds and implants, including multi-functional scaffolds, bioceramics, and titanium-based foams. Finally, Part III reviews further materials with the potential to encourage bone repair and regeneration, including cartilage grafts, chitosan, inorganic polymer composites, and marine organisms.

  • Cognition, Intelligence, and Achievement

    A Tribute to J. P. Das
    • 1st Edition
    • Timothy Papadopoulos + 2 more
    • English
    Cognition, Intelligence, and Achievement is motivated by the work of the renowned Professor J. P. Das on the PASS (Planning, Attention, Simultaneous and Successive Processing) theory of intelligence and CAS measures (Cognitive Assessment System) of cognitive processes. This book reviews current research using this and other frameworks in understanding the relationships among cognition, intelligence, and achievement. The assessment and diagnosis of learning disabilities, mental retardation, and ADHD are addressed, and the interrelationships among cognition, culture, neuropsychology, academic achievement, instruction, and remediation are examined. No other book has presented such an integrated view across these domains, from such a diverse array of internationally known and respected experts from psychology, education, and neuroscience.

  • Colloid and Interface Science in Pharmaceutical Research and Development

    • 1st Edition
    • Hiroyuki Ohshima + 1 more
    • English
    Colloid and Interface Science in Pharmaceutical Research and Development describes the role of colloid and surface chemistry in the pharmaceutical sciences. It gives a detailed account of colloid theory, and explains physicochemical properties of the colloidal-pharmaceut... systems, and the methods for their measurement. The book starts with fundamentals in Part I, covering fundamental aspects of colloid and interface sciences as applied to pharmaceutical sciences and thus should be suitable for teaching. Parts II and III treat applications and measurements, and they explains the application of these properties and their influence and use for the development of new drugs.

  • Cytogenetics of Cells in Culture

    • 1st Edition
    • R. J. C. Harris
    • English
    Cytogenetics of Cells in Culture is a compendium of papers that deals with techniques to detect patterns of DNA replication, cellular control mechanisms, and chromosome analyses with automated instrumentation. Some papers discuss the effects of cell hybridization and of noxious substances such as radiation, chemical agents, and viruses on chromosomal patterns. Other papers focus on the influence of altered chromosomal complement on the survival of cells to long-term tissue culture or to ionizing radiation treatment. A couple of papers points out that naturally occurring chromosomal abnormalities in mammalian populations are relatively rare and are not necessarily associated with physical defects or disease. One paper notes that chromosomes in cells with different functions have different patterns of replication in which the changes are small and hidden. The chromosomes will usually be neutralized showing little of the characteristic pattern of replication or condensation during the early cleavage stages, that will later change into differentiated characteristic ways for each tissue type. Another paper describes chromosome breakage associated with viruses and DNA inhibitors. The compendium can prove beneficial for biochemists, micro-biologists, cellular researchers, and academicians involved in the study of cellular biology or physiology.

  • Neurobiology of Social Behavior

    Toward an Understanding of the Prosocial and Antisocial Brain
    • 1st Edition
    • Michael Numan
    • English
    Social neuroscience is a rapidly growing, interdisciplinary field which is devoted to understanding how social behavior is regulated by the brain, and how such behaviors in turn influence brain and biology. Existing volumes either fail to take a neurobiological approach or focus on one particular type of behavior, so the field is ripe for a comprehensive reference which draws cross-behavioral conclusions. This authored work will serve as the market’s most comprehensive reference on the neurobiology of social behavior. The volume will offer an introduction to neural systems and genetics/epigenetics... followed by detailed study of a wide range of behaviors – aggression, sex and sexual differentiation, mating, parenting, social attachments, monogamy, empathy, cooperation, and altruism. Research findings on the neural basis of social behavior will be integrated across different levels of analysis, from molecular neurobiology to neural systems/behavioral neuroscience to fMRI imaging data on human social behavior. Chapters will cover research on both normal and abnormal behaviors, as well as developmental aspects.

  • Lockhart and Wiseman’s Crop Husbandry Including Grassland

    • 9th Edition
    • Steve Finch + 2 more
    • English
    Increased yields, markets, and profitability have led to changes in crop husbandry. Since its first publication in 1966, revised editions of Lockhart & Wiseman's Crop Husbandry Including Grassland have upheld and increased the book's good reputation. This ninth edition maintains its status as the standard textbook for many agricultural courses. Part one covers the principles of crop production with chapters concerning plants, climate, soil management, fertilizers, manures, weeds, and diseases threatening farm crops. Part two surveys crop husbandry techniques. Environmental impact has been addressed in greater detail in this edition. This section looks at issues such as sustainable crop management, precision farming, and organic crop husbandry. The way these general techniques apply to individual crops is explained in part three. This part considers a range of cereals, combinable break crops, root crops, industrial crops, and fresh produce crops. Part four looks at the use of grassland and forage crops, with chapters considering arable forage crops, the characteristics of grassland, and the corresponding methods for establishing and improving grassland. This part also includes information regarding equine grassland management and conservation of grass and forage crops. This ninth edition of Lockhart and Wiseman's Crop Husbandry Including Grassland is relevant for students throughout the United Kingdom and Europe. It is a useful reference book for agriculture National Diploma courses, Foundation Degrees, and BSc degrees, and is important for Masters level students entering agriculture from another discipline.

  • Cell Growth and Cell Division

    • 1st Edition
    • R. J. C. Harris
    • English
    Cell Growth and Cell Division is a collection of papers dealing with the biochemical and cytological aspects of cell development and changes in bacterial, plant, and animal systems. One paper discusses studies on the nuclear and cytoplasmic growth of ten different strains of the genus Blepharisma, in which different types of nutrition at high and low temperatures alter the species to the extent that they became morphologically indistinguishable. The paper describes the onset of death at high and low temperatures as being preceded by a decrease in the size of the cytoplasm and a corresponding decrease in the size of the macronucleus. The moribund organisms, still possessing structure, are motionless with no distinguishable macronuclear materials. Another paper presents the response of meiotic and mitotic cells to azaguanine, chloramphenicol, ethionine, and 5-methyltryptophan. The paper describes the failure of spindle action, arrest of second division, inhibition of cytokinesis, aberrant wall synthesis, and alterations in chromosome morphology in meiosis cells. In the case of mitosis, a single enzyme—thymidine phosphorylase—shows that reagents which inhibit protein synthesis also inhibit the appearance of that enzyme if the reagent is applied one day before it normally appears. Other papers discuss control mechanisms for chromosome reproduction in the cell cycle, as well as the force of cleavage of the dividing sea urchin egg. The collection can prove valuable for bio-chemists, cellular biologists, micro-biologists, and developmental biologists.

  • Advances in Planar Lipid Bilayers and Liposomes

    • 1st Edition
    • Volume 20
    • English
    Although the origin and the basic meaning of the terms "planar lipid bilayers" and "liposome" have not changed during the years, the present advances in the scientific, technological, biomedical and consumer product fields are remarkable. Ever since its launch the "Advances in Planar Lipid Bilayers and Liposomes’ (APLBL) has provided a global platform for a community of researchers having very broad scientific interests in theoretical, experimental and simulation studies on lipid and cell membrane micro and nanostructures. Ranging from artificial lipid membranes to cell membranes, controlled release of functional molecules, drug delivery to cancer cells, pharmaceutical formulations to food products, the applications are simply enormous. An assortment of chapters in APLBL represents both an original research as well as comprehensives reviews written by world leading experts and young researchers.

  • The Interpretation of Ultrastructure

    • 1st Edition
    • R. J. C. Harris
    • English
    The Interpretation of Ulstrastructure is a collection of papers dealing with techniques in ulstrastructural research such as in fixation, reversed staining, ultrastructure in embryos and in plants, control of observations by light microscopy, and cytochemistry at the electron microscope level. One paper describes various fixatives used on rat liver tissue including a standard osmium tetroxide solution, pure melted osmium tetroxide, and strong osmium tetroxide solutions in carbon tetrachloride. Another paper points out that the use of electron micrographs of the cell nucleus and chromosomes should include approaches to chromosome analysis. For the investigator studying the three dimensional organization of chromosomes, his approaches should include classical cytology and cytogenetics, chemical and cytochemical studies on nuclei, as well as chemical and physical analysis of nucleic acid and nucleoprotein molecules. Several papers discuss the study of natural and artificial DNA-plasma by thin sections, an assessment of negative staining techniques for revealing ultrastructure, and other approaches in the study of biological ultrastructure by high-resolution electron microscopy. The collection will benefit microbiologists, biotechnologists, and academicians connected with the biological sciences.

  • Protides of the Biological Fluids

    Proceedings of the Seventeenth Colloquium, Bruges, 1969
    • 1st Edition
    • H. Peeters
    • English
    Protides of the Biological Fluids documents the proceedings of the XVIITH Colloquium held in Bruges in 1969. This book is divided into three sections. Section A discusses the genetics of the antibody response, focusing on the evolutionary aspects and genetics of differentiation centered on the problems of immunoglobulin structure and deficiencies. The molecular variation occurring in the amino acid sequence of various proteins, its ways of detection and its physiological significance, is presented in Section B. Some of the proteins considered include hemoglobin, fibrinogen, complement, and lipoproteins. Section C is devoted to the developments in theoretical and instrumental aspects of electrofocusing, considering the ampholyte structure and function and techniques, such as gel electrofocusing and preparative column electrofocusing. This compilation is beneficial to researchers and specialists concerned with protides of the biological fluids.

  • Carbohydrate Metabolism

    Comprehensive Biochemistry
    • 1st Edition
    • Volume 17
    • Marcel Florkin + 1 more
    • English
    Comprehensive Biochemistry, Volume 17: Carbohydrate Metabolism focuses on the processes, reactions, and transformations involved in the metabolism of carbohydrates, including glycosaminoglycans, enzymes, oxidation, and glycolysis. The selection first elaborates on functional organization contributing to carbohydrate economy and control of synthesis and breakdown of glycogen, starch, and cellulose. Discussions focus on breakdown of glycogen in mammalian systems, role of glycogen in the regulation of glycogen metabolism, glycogen and starch metabolism in bacteria and plants, carbohydrate digestion, and integration of digestion and absorption. The book also ponders on regulation and mechanisms of enzymes and hexose-monophosphate oxidation, including functions and regulation of pentose-phosphate cycle glucose transport and role of subsequent steps in regulating the rate of glycolysis. The book takes a look at the metabolism of glycosaminoglycans, aldonic and uronic acids, and carbohydrate and oxidative metabolism in neural systems. Concerns include control of carbohydrate metabolism, adaptive changes in relation to carbohydrate metabolism, uronic and aldonic acid metabolism in plants and microorganisms, and mechanism of alternation of monosaccharide units. The selection is a vital source of data for researchers interested in carbohydrate metabolism.

  • Differentiation and Immunology

    Symposia of the International Society for Cell Biology, Vol. 7
    • 1st Edition
    • Katherine Brehme Warren
    • English
    Differentiation and Immunology is a collection of papers that deals with molecular specificity—the link between immunology and differentiation. One paper reviews the status of regulation in bacteria or viruses, and extends the results to animal cells. The paper also investigates a single aspect of the control of immunoglobulin through the use of plasmacytomas. Another paper discusses the role of macrophages in the minimum theory to possibly account for the energetics of the reaction with receptors, or to the frequency of antigen-sensitive cells. Some papers investigate the immunogenic function of macrophages, the transition from monocyte to macrophage, the factors influencing the formation of macrophage lysosomes, and the origin of macrophage lysosomes. Other papers also discuss the immune response as a model system for studies on cellular differentiation, as well as the differentiation for collagen synthesis in cultured cells. One paper suggests that in differentiation, the changes that can occur in the properties of protozoan cells, perpetuated for long periods, are reversible, and can be a means for survival—as every cell line is also capable of being a germ line. This collection can prove valuable to bio-chemists, cellular biologists, micro-biologists, developmental biologists, and scientists involved in immunology research.

  • Drugs, Addiction, and the Brain

    • 1st Edition
    • George F. Koob + 2 more
    • English
    Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain.

  • Neurovirology

    • 1st Edition
    • Volume 123
    • Alex C. Tselis + 1 more
    • English
    This volume in the Handbook of Clinical Neurology series provides a complete review of the history, science and current state of neurovirology. It covers the science and clinical presentation, diagnosis, and treatment of viruses of the brain and central nervous system, and is a trusted resource for scholars, scientists, neuroscientists, neurologists, virologists, and pharmacologists working on neurovirology. Neurovirology has been significantly bolstered by modern technologies such as PCR and MRI with direct impact on isolating viruses and advancing therapeutics based on molecular medicine. These advances are particularly important today with the introduction of emerging and re-emerging diseases such as HIV/AIDS, Nipah encephalitis and the appearance of West Nile encephalitis in the western hemisphere.

  • Natural Hosts of SIV

    Implication in AIDS
    • 1st Edition
    • Aftab A. Ansari + 1 more
    • English
    Natural Hosts of SIV: Implications in AIDS thoroughly reviews the possible mechanisms by which African nonhuman primate natural hosts of lentiviruses remain essentially disease-free while other hosts exhibit disease and death. The book ultimately indicates directions for further research and potential translations of this compelling phenomenon into novel approaches to treat and prevent HIV. When Asian non-human primate non-natural hosts are experimentally infected with viruses isolated from African species, disease and death normally results. Meanwhile, these African nonhuman primate natural hosts maintain similar levels of plasma and cellular viremia and exhibit compellingly different, essentially disease-free, states. This work attempts to answer the question of how the natural host remains disease resistant.

  • Alkyl Polyglucosides

    From Natural-origin Surfactants to Prospective Delivery Systems
    • 1st Edition
    • Ivana Pantelic
    • English
    The on-going ‘green’ trend in the personal care industry coupled with global environmental concerns, place natural-origin, biodegradable and skin-friendly surfactants such as alkyl polyglucosides (APGs) in high demand. After successful use in cosmetics, sufficient data has been obtained to welcome some sugar emulsifiers into the field of drug dosage. Alkyl Polyglucosides presents a comprehensive compendium which guides a researcher from the APG-related preformulation stages to formulation processing, including the investigation of various APG-stabilized systems skin performance. This book introduces various APG representatives, their benefits in relation to certain conventional surfactants, physicochemical and interfacial properties, possible interaction with commonly used ingredients and diverse characterization techniques indispensable for the assessment of colloidal systems. The first chapter introduces alkyl polyglucosides, followed by chapters on their properties, behaviour, an overview of the patent protection mechanisms and guidelines for submitting patent applications. Finally, a conclusion surveys international patent applications involving APGs.

  • Milk Proteins

    From Expression to Food
    • 2nd Edition
    • Mike Boland + 2 more
    • English
    Understanding of the interactions of milk proteins in complex food systems continues to progress, resulting in specialized milk-protein based applications in functional foods, and in protein ingredients for specific health applications. Milk Proteins is the first and only presentation of the entire dairy food chain – from the source to the nutritional aspects affecting the consumer. With focus on the molecular structures and interactions of milk proteins in various processing methods, Milk Proteins presents a comprehensive overview of the biology and chemistry of milk, as well as featuring the latest science and developments. Significant insight into the use of milk proteins from an industry viewpoint provides valuable application-based information. Those working with food and nutritional research and product development will find this book useful.

  • Biochemical Ecotoxicology

    Principles and Methods
    • 1st Edition
    • Francois Gagne
    • English
    Biochemical Ecotoxicology: Principles and Methods presents practical approaches to biochemical ecotoxicology experiments for environmental protection and conservation. With its methodical, stepped approach this essential reference introduces readers to current techniques for toxicity endpoint testing, suitable for laboratories of any size and budget. Each chapter presents a state-of-the-art principle, a quick and inexpensive procedure (including appropriate reagents), case studies, and demonstrations on how to analyze your results. Generic techniques are covered, suitable for a variety of organisms, as well as high-throughput techniques like quantitative polymerase chain reactions and enzyme-linked immunoassays. Cutting-edge approaches, including gPCR arrays and lipidomic techniques, are also included, making this is an essential reference for anyone who needs to assess environmental toxicity.

  • The Rat Nervous System

    • 4th Edition
    • George Paxinos
    • English
    The previous editions of The Rat Nervous System were indispensable guides for those working on the rat and mouse as experimental models. The fourth edition enhances this tradition, providing the latest information in the very active field of research on the brain, spinal cord, and peripheral nervous system. The structure, connections, and function are explained in exquisite detail, making this an essential book for any graduate student or scientist working on the rat or mouse nervous system.

  • An Introduction to Aquatic Toxicology

    • 1st Edition
    • Mikko Nikinmaa
    • English
    An Introduction to Aquatic Toxicology is an introductory reference for all aspects of toxicology pertaining to aquatic environments. As water sources diminish, the need to understand the effects that contaminants may have on aquatic organisms and ecosystems increases in importance. This book will provide you with a solid understanding of aquatic toxicology, its past, its cutting-edge present and its likely future. An Introduction to Aquatic Toxicology will introduce you to the global issue of aquatic contamination, detailing the major sources of contamination, from where they originate, and their effects on aquatic organisms and their environment. State-of-the-art toxicological topics covered include nanotoxicology, toxicogenomics, bioinformatics, transcriptomics, metabolomics, as well as water management and the toxicological effects of major environmental issues such as algal blooms, climate change and ocean acidification. This book is intended for anyone who wants to know more about the impact of toxicants on aquatic organisms and ecosystems, or to keep up to date with recent and future developments in the field.

  • The Polysaccharides

    • 1st Edition
    • Gerald O. Aspinall
    • English
    The Polysaccharides, Volume 2 is a seven-chapter text that presents the status of polysaccharide chemistry and related aspects of biochemistry. The opening chapter is concerned with the major classifications of polysaccharides, such as homoglycans and diheteroglycans. The succeeding five chapters discuss the occurrence, usage, structural studies, conformation, and derivatives of specific carbohydrate group, including cellulose, plant, algal, bacterial, and fungal polysaccharides. The last chapter deals with the industrial application and economic aspects of polysaccharides. This book will prove useful to chemists and biochemists working on polysaccharides and other complex carbohydrates.

  • Sturkie's Avian Physiology

    • 6th Edition
    • Colin G. Scanes
    • English
    Sturkie's Avian Physiology is the classic comprehensive single volume on the physiology of domestic as well as wild birds. The Sixth Edition is thoroughly revised and updated, and features several new chapters with entirely new content on such topics as migration, genomics and epigenetics. Chapters throughout have been greatly expanded due to the many recent advances in the field. The text also covers the physiology of flight, reproduction in both male and female birds, and the immunophysiology of birds. The Sixth Edition, like the earlier editions, is a must for anyone interested in comparative physiology, poultry science, veterinary medicine, and related fields. This volume establishes the standard for those who need the latest and best information on the physiology of birds.

  • Microencapsulation in the Food Industry

    A Practical Implementation Guide
    • 1st Edition
    • Robert Sobel
    • English
    Microencapsulation is being used to deliver everything from improved nutrition to unique consumer sensory experiences. It’s rapidly becoming one of the most important opportunities for expanding brand potential. Microencapsulation in the Food Industry: A Practical Implementation Guide is written for those who see the potential benefit of using microencapsulation but need practical insight into using the technology. With coverage of the process technologies, materials, testing, regulatory and even economic insights, this book presents the key considerations for putting microencapsulation to work. Application examples as well as online access to published and issued patents provide information on freedom to operate, building an intellectual property portfolio, and leveraging ability into potential in licensing patents to create produce pipeline.This book bridges the gap between fundamental research and application by combining the knowledge of new and novel processing techniques, materials and selection, regulatory concerns, testing and evaluation of materials, and application-specific uses of microencapsulation.

  • Bioenergetics 2

    • 1st Edition
    • David G. Nicholls + 1 more
    • English
    Bioenergetics 2 aims to clarify topics such as the thermodynamics of bioenergetic processes and the stoichiometries of energy coupling reactions. The book discusses chemiosmotic energy transduction; ion transport across energy-conserving membranes; and quantitative bioenergenetics as the measurement of driving forces. The text also describes the chemiosmotic proton circuit; the respiratory chain; the photosynthetic generators of protonmotive force; and the ATP synthase. The secondary transport of products across the membrane, as well as the structures of the bacterial photosynthetic reaction center and bacteriorhodopsin are also considered. Biochemists will find the book invaluable.

  • Guide to Biochemistry

    • 1st Edition
    • James C. Blackstock
    • English
    Guide to Biochemistry provides a comprehensive account of the essential aspects of biochemistry. This book discusses a variety of topics, including biological molecules, enzymes, amino acids, nucleic acids, and eukaryotic cellular organizations. Organized into 19 chapters, this book begins with an overview of the construction of macromolecules from building-block molecules. This text then discusses the strengths of some weak acids and bases and explains the interaction of acids and bases involving the transfer of a proton from an acid to a base. Other chapters consider the effectiveness of enzymes, which can be appreciated through the comparison of spontaneous chemical reactions and enzyme-catalyzed reactions. This book discusses as well structure and function of lipids. The final chapter deals with the importance and applications of gene cloning in the fundamental biological research, which lies in the preparation of DNA fragments containing a specific gene. This book is a valuable resource for biochemists and students.

  • Assembly Instructions for Polypeptide Models

    Academic Press/Molecular Design Inc. Precision Molecular Models
    • 1st Edition
    • Edward J. Barrett
    • English
    Assembly Instructions for Polypeptide Models provides assembly procedures for? polypeptide chains and for modeling the ?-helix and the parallel and antiparallel ?-pleated sheets. This text is divided into nine chapters and starts with a brief introduction to the basic unit of polypeptide or protein structure, which is the amino acid. The subsequent chapters deal with the components of the model system, including the torsion angles and the asymmetric ?-carbon atom. The remaining chapters present specific instructions for the construction of free amino acids, polypeptide end groups, side chain groups, secondary structures, and side chain torsion angles. This book will prove useful to protein and peptide scientists, organic chemists, and biochemists.

  • Biological and Biochemical Oscillators

    • 1st Edition
    • Britton Chance + 2 more
    • English
    Biological and Biochemical Oscillators compiles papers on biochemical and biological oscillators from a theoretical and experimental standpoint. This book discusses the oscillatory behavior, excitability, and propagation phenomena on membranes and membrane-like interfaces; two-dimensional analysis of chemical oscillators; and chemiluminescence in oscillatory oxidation reactions catalyzed. The problems associated with the computer simulation of oscillating systems; mechanism of single-frequency glycolytic oscillations; excitation wave propagation during heart fibrillation; and biochemical cycle of excitation are also elaborated. This compilation likewise covers the physiological rhythms in Saccharomyces cerevisiae populations; integral and indissociable property of eukaryotic gene-action systems; and role of actidione in the temperature jump response of the circadian rhythm in Euglena gracilis. This publication is valuable to biochemists interested in biochemical and biological oscillations.

  • Bacterial Metabolism

    • 2nd Edition
    • H. W. Doelle
    • English
    Bacterial Metabolism, Second Edition describes microbial systematics and microbial chemistry and focuses on catabolic events. This book deals with the progress made in bacterial metabolism that includes data on regulatory mechanisms; comparison of bacterial growth kinetics with enzyme kinetics; aerobic amino acid catabolism; and the glucose transport mechanism. This text also emphasizes the development of photosynthetic phosphorylation in the different bacterial families. This book explains anaerobic respiration and carbohydrate metabolism—glucose, fructose, lactose, mannose, allose, and sorbitol. This text then describes aerobic respiration including the "Nitroso" and "Nitro" groups of genera, and the Knallgas bacteria, which use the reaction between molecular hydrogen and molecular oxygen as their source of energy. This book also explains the microbial transformation of iron as caused by either specific organisms (e.g. Ferrobacillus ferrooxidans) or nonspecific organisms. This selection also explains the process of fermentation by Enterobacteriaceae, lactic acid bacteria, and proteolytic clostridia. This text can be valuable for microchemists, microbiologists, students, and academicians whose disciplines are in biological chemistry and cellular biology.

  • Virus Structure

    • 1st Edition
    • Robert W. Horne
    • English
    Virus Structure describes the physical characteristics of isolated viruses that represent typical structural groups, with particular reference to those features analyzed with the aid of the electron microscope. For descriptive purposes, the book has been divided into sections starting with the small icosahedral viruses and leading to the larger and more sophisticated structures, regardless of whether they are animal, plant, or bacterial viruses. These include double-stranded DNA icosahedral viruses, herpesvirus, viruses with helical symmetry, and viruses with complex or a combination of symmetries. Many common architectural features will be found in those viruses selected for discussion in each of the sections, and for these reasons the introduction places some emphasis on the symmetry elements rather than the shapes of viruses. The mechanism by which viruses enter host cells and the events that follow once the cell has been infected are only mentioned briefly as the virus-host interaction is a relatively complex one.

  • Rapid Virus Diagnosis

    Application of Immunofluorescence
    • 2nd Edition
    • P. S. Gardner + 1 more
    • English
    Rapid Virus Diagnosis: Application of Immunofluorescence presents developments in immunofluorescence as a technique for the diagnosis of virus infections. It discusses the effective and rapid methods for the diagnosis of virus infections. It addresses the application of fluorescent antibody techniques to the diagnosis and the investigation of virus infections and the assessment of their value both to the clinician and to the virologist. Some of the topics covered in the book are the fluorescence microscopy; nature of fluorescence; filter systems; transmitted light microscopy; interference filters for transmitted light microscopy; lamp centration and alignment of microscope; contrast-fluorescenc... condensers; photomicrography; and choice of microscope. The culture of viruses for production of antiserum is fully covered. The selection of cell lines or tissues for virus culture is discussed in detail. The text describes in depth the fluorescent antibody staining techniques. The preparation of specimens from respiratory infections is presented completely. A chapter is devoted to the respiratory syncytial virus. Another section focuses on the analysis influenza virus, paramyxoviruses, and picornaviruses. The book can provide useful information to doctors, virologists, students, and researchers.

  • Protein Turnover and Lysosome Function

    • 1st Edition
    • Harold L. Segal + 1 more
    • English
    Protein Turnover and Lysosome Function comprises the proceedings of a symposium under the same title held at the State University of New York at Buffalo on August 21-26, 1977. The book discusses mechanisms of protein turnover, as well as the identification and characterization of intracellular proteases. The text also describes the internalization of macromolecules into the intracellular digestive system; the types of specificity entailed; and the fate of the membrane material involved in the vacuolization process. Biochemists, pathologists, cell biologists, molecular biologists, and physiologists will find the book invaluable.

  • The Antibody Molecule

    • 1st Edition
    • Alfred Nisonoff + 2 more
    • F. J. Dixon + 1 more
    • English
    The Antibody Molecule reviews the literature leading to current knowledge of the structure of immunoglobulins. The book begins by outlining some of the basic structural characteristics of immunoglobulins without citing the references on which the information is based. Separate chapters follow covering the chemical nature of the active site of an antibody molecule and mechanisms of interaction with hapten; the general structural features and properties of the various classes of human immunoglobulin; and amino acid sequences of human and mouse L chains and of human and rabbit H chains. Subsequent chapters deal with the evolution of the immunoglobulin classes; special properties of mouse, guinea pig, rabbit, and horse immunoglobulins; idiotypic specificities of immunglobulins; and the genetic control of antibodies. This book is meant for immunologists who have not personally observed the development of this exciting period in the history of immunology. It will also provide useful supplemental reading for the serious student or investigator who wishes to become familiar with the nature of the antibody molecule, its genetic control, and mode of action.

  • Viral Immunology and Immunopathology

    • 1st Edition
    • Abner Louis Notkins
    • English
    Viral Immunology and Immunopathalogy covers topics concerning the role of cellular and humoral immunity in viral infections, factors responsible for the persistence and recurrence of viral infections in the presence of immunity, mechanisms of viral immunopathology, and concepts in the development of vaccines. The book describes the history of viral immunology; the synthesis and properties of viral antigens; and the humoral immune response to viruses. The text also discusses the mechanisms of viral neutralization; cellular immunity; the role of inflammatory cells and effector molecules in combating viral infections; and the genetic control of resistance. The book concludes with chapters on herd immunity; viral immunopathology; and viral immunology and immunopathology. Immunologists, pathologists, virologists, and microbiologists will find the book useful.

  • Clinical Biochemistry of Domestic Animals

    • 3rd Edition
    • Jiro J. Kaneko
    • English
    Clinical Biochemistry of Domestic Animals, Third Edition, represents a major revision of the previous editions. Since the publication of the first edition of ""Clinical Biochemistry of Domestic Animals,"" veterinary clinical biochemistry has enjoyed a virtual explosion of new knowledge commensurate with the increased importance of companion animals, the livestock industry, and experimental animals. This third edition brings together some of the most important areas of clinical biochemistry pertinent to these sectors. For this purpose, new chapters on the reproductive hormones and clinical enzymology have been added, in addition to a rewriting of the chapters on renal function and plasma proteins and extensive revisions of all other chapters. The volume contains 18 chapters and opens with discussions of carbohydrate and lipid metabolism and associated disorders. This is followed by separate chapters on serum proteins and the dysproteinemias; porpyhrins; clinical enzymology; liver, pancreatic, and kidney function; and the physiology and pathophysiology of body fluids. Subsequent chapters deal with pituitary, adrenal, and thyroid function; skeletal muscle function; calcium, phosphorus, magnesium, and iron metabolism; the mechanisms of homeostasis; and cerebrospinal fluid physiology.

  • Psychoneuroimmunology

    • 1st Edition
    • Robert Ader
    • English
    Psychoneuroimmunolog... Second Edition presents reports on the relationship between the nervous and immune systems. The book is divided into four sections. The first section details the role of neural structures and neurotransmitter signals in communication with the immune system. It documents the extensive neural connections with organs of the immune system; the dynamics of noradrenergic sympathetic innervation of spleen and thymus; and the evidence for immune signaling of the CNS. Part II elaborates the role of hormones in the modulation of immune functions; the basis for bidirectional communication between the neuroendocrine and immune systems; and the potential physiological implications of these neuroendocrine-immun... system interactions. The third part addresses behavioral influences on immune response; the effects of conditioning, stress and social interactions in modulating immune responses; and the behavioral consequences of experimentally altered or genetically determined immunologic states. The final section presents the effects of psychosocial factors on immune responses and the potential impact of behavioral interventions in modulating immunity in healthy human subjects and in patients with AIDS. Neuroscientists, endocrinologists, and immunologists will find the book interesting.

  • Membranes and Viruses in Immunopathology

    • 1st Edition
    • Stacey B. Day + 1 more
    • English
    Membranes and Viruses in Immunopathology covers the proceedings of the 1972 symposium by the same title, held at the University of Minnesota Medical School, sponsored by the Bell Museum of Pathology. This book is composed of 40 chapters that highlight the significant advances in fundamental experiments of membrane structure chemistry. Considerable chapters explore the diagnosis and analysis of slow and oncogenic virus infections, as well as the role of immunobiologic processes in the pathogenesis, prevention, and treatment of disease. The remaining chapters contain research works on the detailed mechanisms that may contribute to cancer induction and dissemination. This book will prove useful to immunopathologists and practicing physicians.

  • Experimental Manipulation of Gene Expression

    • 1st Edition
    • Masayori Inouye
    • English
    Experimental Manipulation of Gene Expression discusses a wide range of host systems in which to clone and express a gene of interest. The aims are for readers to quickly learn the versatility of the systems and obtain an overview of the technology involved in the manipulation of gene expression. Furthermore, it is hoped that the reader will learn enough from the various approaches to be able to develop systems and to arrange for a gene of particular interest to express in a particular system. The book opens with a chapter on the design and construction of a plasmid vector system used to achieve high-level expression of a particular phage regulatory protein normally found in minute amounts in a phage-infected bacterial cell. This is followed by separate chapters on topics such as high-level expression vectors that utilize efficient Escherichia coli lipoprotein promoter as well as various other portions of the lipoprotein gene Ipp; DNA cloning systems for streptomycetes; and the design and application of vectors for high-level, inducible synthesis of the product of a cloned gene in yeast.

  • Bacterial Metabolism

    • 1st Edition
    • H. W. Doelle
    • English
    Bacterial Metabolism focuses on metabolic events that occur in microorganisms, as well as photosynthesis, oxidation, polysaccharide formation, and homofermentation. The book first discusses the thermodynamics of biological reactions, photosynthesis and photometabolism, and chemosynthesis. Free energy, photosynthesis, enzymes, and terminology in bacterial metabolism are elaborated. The manuscript then examines acetic acid bacteria and lactic acid bacteria. Discussions focus on lactate, ethanol, glucose, and glycerol metabolism, glycol oxidation, homofermentation, polysaccharide formation, and electron transport systems. The publication takes a look at pseudomonadaceae and nitrogen metabolism as an energy source for anaerobic microorganisms. Topics include metabolism of pairs of amino acids, single amino acid metabolism, oxidation of glycolate and malonate, and oxygenases. The book is a dependable source of information for readers interested in bacterial metabolism.

  • Immunological Tolerance

    Mechanisms and Potential Therapeutic Applications
    • 1st Edition
    • David H. Katz + 1 more
    • English
    Immunological Tolerance: Mechanisms and Potential Therapeutic Applications documents the proceedings of a conference held at Brook Lodge, Michigan, April 27-May 1, 1974. The conference brought together many of the investigators who have actively contributed to furthering knowledge and understanding of immunological tolerance. It will be immediately clear to the reader that the conference was structured in a way to consider phenomena of tolerance and immune suppression as interrelated entities with a certain degree of emphasis on the possible common cellular mechanisms involved. The volume contains 36 contributions presented during the seven sessions of the conference. The papers presented in Session I examined T-cell tolerance. The presentations in Session II focused on B cell tolerance. The papers in Sessions III and IV focused on the mechanisms of B cell and T cell tolerance, respectively. Session V dealt with the activity of suppressor cells as a mechanism of tolerance. The papers in Session VI investigated the suppressive activity of antibody and antigen-antibody complexes. In Session VII a final General Discussion was held in order to identify what has been established concerning the phenomenology and mechanisms of specific immunological tolerance, what are the major unresolved issues, and what approaches appear most promising to answer these questions.

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