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Advances in Planar Lipid Bilayers and Liposomes
- 1st Edition, Volume 20 - July 15, 2014
- Editors: Aleš Iglič︎, Chandrashekhar V. Kulkarni
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 4 1 8 6 9 8 - 9
- eBook ISBN:9 7 8 - 0 - 1 2 - 4 1 9 9 5 9 - 0
Although the origin and the basic meaning of the terms "planar lipid bilayers" and "liposome" have not changed during the years, the present advances in the scientific,… Read more
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Request a sales quoteAlthough the origin and the basic meaning of the terms "planar lipid bilayers" and "liposome" have not changed during the years, the present advances in the scientific, technological, biomedical and consumer product fields are remarkable. Ever since its launch the "Advances in Planar Lipid Bilayers and Liposomes’ (APLBL) has provided a global platform for a community of researchers having very broad scientific interests in theoretical, experimental and simulation studies on lipid and cell membrane micro and nanostructures. Ranging from artificial lipid membranes to cell membranes, controlled release of functional molecules, drug delivery to cancer cells, pharmaceutical formulations to food products, the applications are simply enormous. An assortment of chapters in APLBL represents both an original research as well as comprehensives reviews written by world leading experts and young researchers.
- Gives a survey on recent theoretical as well as experimental results on lipid micro and nanonanostructures
- In addition, the potential use of the basic knowledge in applications like clinically relevant diagnostic and therapeutic procedures, biotechnology, pharmaceutical engineering and food products is presented
The APLBL book series not only serves as a podium for non-specialists working on interdisciplinary fronts but also retains its special significance for experts in the field of chemistry, physics and biology of lipid micro and nanostructures and biological membranes
PrefaceOne: Biomimetic Membrane Supported at a Metal Electrode Surface: A Molecular ViewAbstract1 Introduction2 sBLM Preparation Methods3 Potential Drop Across the Membrane and an Estimate of the Electric Field Acting on the Membrane4 Effect of the Potential Applied to the Gold Electrode on the Membrane Stability: AFM, NR, and Surface-Enhanced Infrared Absorption Spectroscopy Studies5 Imaging Aggregation of Antibiotic Peptides in a Lipid Membrane6 Potential-Controlled Changes in the Orientation and Conformation of Peptides and Peripheral Proteins: IR Studies of Gramicidin and Cholera Toxin B7 Summary and ConclusionsAcknowledgmentTwo: Lipid Monolayers at the Air–Water Interface: A Tool for Understanding Electrostatic Interactions and Rheology in BiomembranesAbstract1 Introduction2 Experimental Approaches on Monolayers3 Phase Diagrams: Two-Phase Regions4 Distribution of the Phases in the Plane of the Monolayer5 In-Plane Interactions and Consequences on Film Effective Rheology6 Comparison Between Different Model Membranes7 SummaryAcknowledgmentsThree: Langmuir–Blodgett Approach to Investigate Antimicrobial Peptide–Membrane InteractionsAbstract1 Introduction2 Target Membrane Architecture3 The Role of Phospholipids4 Lipid Monolayers5 Effect of Phospholipid Packing Characteristics and Lipid Phase Transitions on Membrane Stability6 Visualization of Lipid Films7 ConclusionFour: Divalent Metal Cations in DNA–Phospholipid BindingAbstract1 Introduction2 DNA–Phospholipid–Divalent Metal Cation Interaction3 Divalent Metal Cations as a Mediator of DNA–Neutral Phospholipid Bilayer Binding4 The Structural Variety of DNA–PC–Me2 + Aggregates5 ConclusionAcknowledgmentsFive: Solid-Like Domains in Mixed Lipid Bilayers: Effect of Membrane Lamellarity and Transition PathwayAbstract1 Introduction2 Materials and Methods3 Results and Discussion4 Summary and OutlookAcknowledgmentsSix: Hexagonal Phase Formation in Oriented DPPC–Melittin Samples: A Small-Angle X-ray Diffraction StudyAbstract1 Introduction2 Materials and Methods3 Results and DiscussionAcknowledgmentSeven: Probing the Self-Assembly of Unilamellar Vesicles Using Time-Resolved SAXSAbstract1 Introduction2 Experimental Method3 SAXS Analysis of Unilamellar Vesicles4 Summary and OutlookAcknowledgmentsEight: Defects in Planar Cell Polarity of Epithelium: What Can We Learn from Liquid Crystals?Abstract1 Introduction2 Liquid Crystals3 Principles of Pattern Formation in Epithelial Tissues4 Results5 DiscussionIndex
- No. of pages: 238
- Language: English
- Edition: 1
- Volume: 20
- Published: July 15, 2014
- Imprint: Academic Press
- Hardback ISBN: 9780124186989
- eBook ISBN: 9780124199590
AI
Aleš Iglič︎
Aleš Iglič received his B.Sc. and Ph.D. degrees in physics and M.Sc. degree in biophysics from the Department of Physics, and the Ph.D. degree in electrical engineering from the Faculty of Electrical Engineering, all from the University of Ljubljana. He is a Full Professor and the Head of Laboratory of Biophysics of the Faculty of Electrical Engineering at University of Ljubljana. His main research interests are in electrostatics, mechanics and statistical physics of lipid nanostructures and biological membranes. He is devoted to higher education, basic research in biophysics and close contacts to clinical practice. Prof. Iglič was visiting scientist and professor at Åbo Academy University in Turku (Finland), Friedrich Schiller University in Jena (Germany) and Czech Technical University in Prague (Czech Republic). He established collaborations with researchers from different universities across the Europe, USA and India and was supervisor of many M.Sc., Ph.D. and postdoctoral students from Slovenia, Czech Republic, Poland, Iran, Bulgaria, Germany, India and Israel. Since 2009 is the editor of Elsevier book series »Advances in Planar Lipid Bilayers and Liposomes« (APLBL).
Affiliations and expertise
Full Professor and Head of Laboratory of Biophysics, Faculty of Electrical Engineering, University of Ljubljana, SloveniaCK
Chandrashekhar V. Kulkarni
Chandrashekhar V. Kulkarni received his PhD in Chemical Biology from University of London for which he was in receipt of a Marie Curie Early Stage Researcher Fellowship at Imperial College London (2005-2008). Earlier he completed his BSc (1999) and MSc (2001) in Chemistry from Shivaji University Kolhapur, India and started his research career at the National Chemical Laboratory Pune, India. He had a few postdoc stints at University of Graz-Austria, University of Bayreuth-Germany and University of Cambridge-UK during which he worked on a wide range of projects. In March 2013 Dr Kulkarni started ‘Lipid Nanostructures Group’ focussing on highly interdisciplinary and cutting-edge projects. Some of his research interests include complex biomembranes and biomolecule interactions, nanostructured lipid particles as carrier systems, and novel nano-bio-applications of lipid nanostructures. Dr Kulkarni joined the editorial board of APLBL in early 2013 and later as an editor of this book series.
Affiliations and expertise
University of Central Lancashire, UK