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Elsevier

Books in Life sciences

  • Climate Change and Disability

    A Collaborative Approach to a Sustainable Future
    • 1st Edition
    • Marcalee Alexander + 2 more
    • English
    Until recently, little attention has been paid to the concerns of people living with disabilities during extreme weather events and long-term climate changes. Climate Change and Disability: A Collaborative Approach to a Sustainable, Inclusive Future for All delineates the general and specific risks of climate change for people living with disabilities and how we can use accessible approaches to mitigate, adapt, and control these risks, while maximizing opportunities for people living with disabilities. The book opens with an introduction on how we got here. The book continues with sections on actions and research, the physiologic impact of different disabilities, and discussions of specific continents and countries, where issues related to climate change exist. Education and advocacy are covered in detail, and the book wraps up with a section on action and research, detailing how to respond to extreme weather events including how various types of disabilities are impacted by different events.Climate Change and Disability: A Collaborative Approach to a Sustainable, Inclusive Future for All serves as a guide for a broad audience at the crossroads of environmental adaptation and human health. Physicians, as well as nurses, physical and occupational therapists, and other allied health professionals will find it valuable for tailoring care for people living with disabilities due to climate change. Advocates and individuals living with disabilities will gain insight into advocacy for inclusive policies and personal preparedness. Scientists and clinicians interested in the health and societal impacts of climate change will find it useful in informing their research and practice. Policymakers and politicians can utilize this resource to develop equitable climate strategies, ensuring that environmental justice concerns are inclusive.

  • Advancements in the Treatment and Prevention of Breast Cancer

    • 1st Edition
    • Dileep Kumar
    • English
    Advancements in the Treatment and Prevention of Breast Cancer highlights the significance of early detection, risk assessment, and comprehensive care in mitigating the burden of breast cancer within communities. It not only offers insights into the genetic basis of breast cancer susceptibility, familial risk assessment, and emerging genetic testing technologies but also empowers patients and their families with knowledge about available treatment options, clinical trials, and support resources.In 14 chapters this book provides an in-depth analysis of translational research focusing on understanding the etiology of breast cancer, elucidating potential avenues for primary prevention strategies. It offers a comprehensive overview of recent breakthroughs in understanding the molecular mechanisms underlying breast cancer development and discussing novel targeted treatment approaches derived from these advances but also discusses strategies for minimizing treatment-related toxicity in breast cancer management, including supportive care measures and personalized treatment approaches. This book is a valuable resource for anyone interested in the latest developments in breast cancer care and provides clear explanations of complex scientific topics and will offer insights that can help improve patient care and outcomes.

  • AI Technologies for Crop Breeding

    • 1st Edition
    • Jen-Tsung Chen
    • English
    AI Technologies for Crop Breeding offers the latest insights into the use of artificial intelligence models to improve plant health and production. Presenting applications of AI technologies in plant biology, biotechnology, and crop breeding, it explores practices for the mitigation of biotic and abiotic stressors as well as other plant growth challenges.AI-based technologies are expected to advance approaches to plant functional genomics and multiple omics, resulting in smarter and more efficient crop breeding for next-generation agriculture helping to address the challenges of the increasing human population and the globally changing climate. AI tools such as machine learning, particularly deep learning, have been applied to predict chief players in complicated biological networks, increasing the understanding of in-depth mechanisms of plant-pathogen and plant-environment interactions. Additionally, responses of plants facing stress can be modeled using AI technologies, and the resulting data are valuable not only to plant stress physiology but also for stress-resilient and disease-resistant crop breeding.This book introduces AI technologies for studying plant biology, focusing on machine learning and deep learning models for integrating multiple omics approaches and revealing the knowledge of plant functional genomes. Technological advancements and emerging applications of machine learning and deep learning in genomic selection, genome-wide association study (GWAS), phenotyping and constructing phenomics, and transcriptomics are also featured in this book.AI Technologies for Crop Breeding is an ideal reference for researchers, academics, and advanced-level students and professors in the fields of plant sciences, plant stress physiology, bioinformatics, systems biology, and crop breeding.

  • Ketamine

    Fundamentals, Applications, Pharmacology, and Clinical Aspects
    • 1st Edition
    • Albert Dahan + 1 more
    • English
    Pharmacology of Ketamine: Fundamentals, Applications, Delivery Systems and Clinical Aspects explores the multifaceted properties of ketamine for diverse applications, delving into dosing strategies, routes of administration, and their pharmacological implications. The book begins with an introduction that underscores the need to bridge research and practice. It then delves into the pharmacological intricacies of ketamine, dissecting mechanisms and dosing strategies and exploring the diverse routes of administration and their impact on ketamine's metabolites.The book then explores the PK and PD characteristics of ketamine, followed by a deep dive into clinical applications emphasizing anesthesia, psychiatric therapy, and emerging treatments. The final part of the book covers addiction, toxicity, and future research perspectives. It will serve as a comprehensive reference tailored to the needs of both researchers and clinicians involved in the administration and study of ketamine.

  • Artificial Metalloproteins

    • 1st Edition
    • Volume 720
    • English
    Artificial Metalloproteins covers artificial metalloproteins (ArMs) and how they have emerged as powerful vehicles with which to control, implement, and leverage the unique reactivity and spectroscopic properties of their bound metal ions. Chapters in this release include Incorporating Non-Native Cofactors into Heme Proteins, Designing 4-Helix Bundles to Bind Porphyrin/Porphyrin-... Cofactors, Cobalt-Substituted Hemoprotein Expression, Rationally designed directed evolution of cytochrome P450 enzymes, De novo design of a switchable a-helical hemoprotein, Primary Coordination Sphere Part B: Unnatural Metal-Binding Sites Beyond the Heme, and more.Other sections cover Unnatural Amino Acid Incorporation for Creating Artificial Metalloenzymes, Development of a PQQ-Dependent Artificial Metalloprotein, Evolutionary Engineering of a Rhodium Complex-Linked Artificial Metalloenzyme, Design and Application of Nonheme Iron Enzymes, Part C: Secondary Sphere Modulation for Metallocofactor Activation, Designing Artificial Metalloenzymes by Engineering the Primary and Secondary Coordination Sphere in Native Protein Scaffolds, and much more.

  • Data-Driven Diagnostics and Disease Prediction with AI Optimization

    • 1st Edition
    • Shailendra Pratap Singh + 3 more
    • English
    Data-Driven Diagnostics and Disease Prediction with AI Optimization provides useful insights into model creation, data preparation, and ethical issues for healthcare applications. The book covers all the conventional and non-conventional methods related to this domain. It also discusses AI-based optimization techniques, Machine Learning models, and Advanced AI, offering practical insights, case studies, and optimization strategies to help data scientists and researchers efficiently employ AI in diagnostics and illness prediction in a world where precise diagnostics and early illness prediction may save lives and healthcare resources.

  • Fungal and Protozoan Carbonic Anhydrases

    • 1st Edition
    • Volume 57
    • English
    Fungal and Protozoan Carbonic Anhydrases, Volume 57 in The Enzymes series, explores recent advancements in the study of fungal and protozoan carbonic anhydrases (CAs). This volume presents a comprehensive collection of chapters covering various aspects of these enzymes, including an overview of fungal and protozoan CAs (genetics, molecular biology, and phylogenetics), the structure and function of fungal α-carbonic anhydrases, and an in-depth look at β-carbonic anhydrases in Saccharomyces cerevisiae, Candida spp., and Cryptococcus neoformans.Additiona... chapters delve into the Malassezia spp. and Sordaria macrospora CAs, as well as protozoan CAs from Plasmodium falciparum, Trypanosoma cruzi, Leishmania spp., Toxoplasma gondii, and Entamoeba histolytica. The volume also addresses the challenges in developing selective fungal and protozoal CA inhibitors as anti-infective agents, providing insights into their potential biomedical applications.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 129
    • English
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Advanced Cancer Research Protocols

    • 1st Edition
    • Volume 198
    • English
    Advanced Cancer Research Protocols, Volume 198 is a comprehensive and cutting-edge resource dedicated to the latest methodologies and protocols in the field of cancer research. Topics in this new release include Introduction to Cancer Biology and Current Research Trends, Cell Culture Techniques for Cancer Research, Practical Approaches to Advanced Molecular Biology Techniques, High-throughput sequencing Technologies for Cancer Genomics, Epigenetic Analysis in Cancer Research, Proteomics and Metabolomics in Cancer Biomarker Discovery, In vivo Cancer Modeling Using Mouse Models, and much more.Other sections highlight advances in Advanced Imaging Techniques for Cancer Research, Cancer Stem Cell Analysis and Targeting, Immunotherapy and Cancer Vaccine Development, Gene Editing Techniques in Cancer Research, Single-Cell Analysis in Cancer Research, Liquid Biopsy and Circulating Tumor Cell Analysis, and Exploring the Tumor Microenvironment in Solid Cancer: From Biology to Therapy.

  • Temperate Tree Fruits and Nuts

    • 1st Edition
    • George Manganaris
    • English
    Temperate Tree Fruits and Nuts serves as a comprehensive resource, providing up-to-date knowledge about economically significant temperate fruit crops. This textbook covers the history, genetic improvements, and growth physiology of these crops. It details orchard establishment, management practices, and harvest considerations, making it a standalone guide to sustainable fruit crop production in temperate climates. Targeted toward undergraduate and postgraduate students, as well as professionals in pomology, horticulture, and related fields, the book is essential for researchers, farmers, consultants, and agribusiness professionals.Each chapter, authored by an expert, provides an introduction, botany, orchard management, propagation, rootstocks, cultivars, and disease and pest management. It also covers ripening, harvest criteria, postharvest physiology, and technology, complemented by high-quality illustrations and a question bank for instructors.

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