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Books in Life sciences

  • Navigating the Complexities of SARS-CoV-2 Immunobiology

    The Science Behind the COVID-19 Pandemic
    • 1st Edition
    • Volume 213
    • English
    Navigating Complexities of the SARS-CoV-2 Immunobiology: The Science behind the COVID-19 Pandemic offers a comprehensive exploration of the immune response to COVID-19. This volume brings together research and insights from leading experts to address key aspects of COVID-19 immunology, including T cell responses, cytokine storms, immune evasion strategies, and the impact on preexisting conditions. It also examines the long-term implications of the disease, such as long COVID and its intersection with autoimmunity, as well as the role of the microbiome. This compilation provides a deep understanding of the durability of immune responses post-infection and vaccination, presenting novel perspectives on therapeutic approaches and the path forward in combating this global pandemic.

  • Current Topics in Developmental Biology

    Fertilization and Activation of Development
    • 1st Edition
    • Volume 162
    • English
    Fertilization and Activation of Development, Volume 162 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.Chapters in this new release include Fertilization and the fast block to polyspermy in the African Clawed Frog, Xenopus laevis: A historical perspective, The Mammalian Egg's Zona Pellucida, Fertilization, and Fertility, Function, structure, and regulation of the broadly conserved gamete membrane fusion protein, HAP2, Gamete activation for fertilization and seed development in flowering plants, Paternal contributions to mammalian zygote, and much more.Additional sections cover Ovarian follicle formation and activation, Cytoskeletal dynamics in gamete (pro)nuclear migration across flowering plants, animals, and yeast, and Luteinizing hormone-induced changes in the structure of mammalian preovulatory follicles.

  • Translational Gastroenterology

    • 1st Edition
    • Adam E.M. Eltorai + 3 more
    • English
    Translational Gastroenterology covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. Readers will learn important concepts, including case-control study, prospective cohort study, randomized trials, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in gastroenterology, and know what is needed in collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation.The book provides valuable discussions of the critical appraisal of published studies in gastroenterology, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every medical researcher or gastroenterologist who has ever had a good clinical idea but not the knowledge of how to test it.

  • Gender Affirming Vaginoplasty

    • 1st Edition
    • Gennaro Selvaggi + 1 more
    • English
    Gender Affirming Vaginoplasty is a novel reference of the latest research on those who present with Gender Dysphoria and desire surgery. The book describes the history of Gender Affirming Vaginoplasty (GAV), including social, legal, and ethical aspects of GAV, and explains updated Standards of Care. Users will find sections on preparation for surgery, different surgical techniques available (inclusive with the most recent developments), surgical results and complications, ways to solve complications, and finally, surgical procedures for persons who are requesting nonbinary genital surgery, and for those who are requesting reversal surgery.This is an unprecedented resource for all surgeons from various specialties already involved in gender-affirmative surgery and colleagues interested to gain state-of-the-art knowledge and experience in this field included plastic surgeons, urologists and gynecologists. Gender centers and trainees, scientists, researchers in transgender health, and organizations involved in trans health.

  • Whole Cell Biocatalysis

    Fundamentals and Applications
    • 1st Edition
    • Sergio Huerta-Ochoa + 2 more
    • English
    Whole Cell Biocatalysis, a volume in the Foundations and Frontiers of Enzymology series, offers a detailed overview of the process of biocatalysis using whole cells as an alternative to enzyme biocatalysis. The book examines the potential applications and advantages of whole cell biocatalysis, including its use in the production of fine chemicals, renewable energy, and drug discovery and development. Whole cell biocatalysis for large scale production and non-conventional media are also covered. In addition, the latest methods and techniques are investigated, including cell immobilization, permeabilization, synthetic biology, computational metabolic engineering, and molecular genetics.This book provides a comprehensive summary on whole cell biocatalysis and the latest developments in this emerging field. It is an invaluable reference for researchers working across biochemistry, enzymology, biotechnology, and related fields.

  • Medicinal Plant Research in Africa

    Advances in Pharmacology and Chemistry
    • 2nd Edition
    • Victor Kuete
    • English
    Medicinal Plant Research in Africa, second edition is an updated and complete reference on the pharmacology of most relevant African species and their phytochemical properties. Although pharmacopoeias of most African countries are available and contain an impressive number of medicinal plants used for various therapeutic purposes, however there was no global standard book on the nature and specificity of chemicals isolated in African medicinal plants. This book has set the standard when it first published in 2013 and now is updated with novel phytochemicals belonging to diverse classes of terpenoids, phenolics, and alkaloids. The first chapter cover monoterpenes and related phytochemicals and is followed by sesquiterpenes on chapter two. Chapter tri reviews diterpenoids and chapter four provides an overview of triterpenes and steroids. Essential oils, simple phenols, phenolic acids and related esters come next in chapters five and six, respectively. The following chapters cover coumarins, flavonoids, quinones, xanthones, lignans and stilbenes. Tannins, alkaloids, and ceramides. Chapters 15 to 20 focus on specific health conditions starting with antibiotic infection, antimalarial and other antiprotozoal diseases, cytotoxic and anticancer activity, anti-inflammatory and analgesic action, antidiabetic botanicals and the applications of African plant phytochemicals on reproductive, cardiovascular, and central nervous systems conditions. The final chapter covers the market and industry updates since the first edition published. "Medicinal Plant Research in Africa, 2 Ed." provides a complete overview of the main phytochemical principles present in the African flora and their pharmaceutical use. Pharmaceutical scientists, Ethnopharmacists, botanists, and medicinal chemists will benefit from the content organization and the inclusion of the most recent methods for structural identification of phytochemicals, pharmacological techniques, and data interpretation.

  • Atlas of Marine Invertebrate Larvae

    • 2nd Edition
    • Michael J. Boyle + 2 more
    • English
    Atlas of Marine Invertebrate Larvae, Second Edition covers the origins and history of marine larval science, contemporary state-of-the-art approaches to larval development and biology, and the highest-quality images and schematics showing the broadest diversity of marine larvae in the animal tree of life. This book illustrates larval body plans, the anatomy of their organ systems (muscular, sensory, digestive), including distinct ciliation patterns that facilitate swimming, and the complex metamorphic changes they undergo between different larval and growth stages. Each chapter contains in-text references that direct readers to both historical and contemporary research on the forms, functions, behaviors and biogeographical distributions of marine larvae.This book is a valuable and foundational resource for biologists across various disciplines, including biodiversity, biogeography, and developmental biology. Ecologists, taxonomists, oceanographers, and environmental scientists also benefit from the complete coverage of marine larval forms offered by this book. Additionally, the broad scope and phyletic coverage of marine biodiversity presented in this atlas is ideal for students in oceanography and marine biology, animal development, biological oceanography and invertebrate zoology.

  • Chest Blunt Trauma

    A Modern Approach to a Multidisciplinary Disease
    • 1st Edition
    • Piergiorgio Solli + 1 more
    • English
    Chest Blunt Trauma: A Modern Approach to a Multidisciplinary Disease provides novel treatment ideas for cardiothoracic injuries. The book interweaves knowledge of new surgical techniques, better understanding of patho-physiologic effects of injuries, and enhanced intensive care methods to create a holistic strategy of patient support. This text is a welcome addition for any clinician or researcher seeking refreshed information on the management of trauma to the chest wall.While non-operative treatment has long been the standard of care, the book discusses the vast improvements in understanding how to treat cardiothoracic injuries. Innovative surgical techniques, instruments, post-operative care, and the multisystemic nature of this illness.

  • Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies

    • 1st Edition
    • Volume 291
    • English
    Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies is a comprehensive exploration of how stress affects the brain at a molecular level and its broader implications for mental and neurological health. The book delves into the mechanisms by which stress triggers changes in brain function, including the activation of the hypothalamic-pituita... (HPA) axis, synaptic plasticity alterations, oxidative stress, neuroinflammation, and mitochondrial dysfunction. It examines how these molecular processes contribute to conditions such as neurodegeneration, anxiety, depression, and other stress-related disorders. Furthermore, the book provides an in-depth analysis of current therapeutic interventions, both pharmacological and behavioral, as well as natural antidotes that aim to mitigate the adverse effects of stress on the brain. By synthesizing evidence from cutting-edge research, this book offers valuable insights for scientists, clinicians, and mental health professionals seeking to understand and address the complex interplay between stress and brain health.

  • Tumor-Targeting with Stimuli-Responsive Vesicular Nanocarriers

    Basics to Emerging Applications
    • 1st Edition
    • Ankit Jain + 2 more
    • English
    Tumour-Targeting with Stimuli Responsive Vesicular Nanocarriers: Basics to Emerging Applications not only acquaints scientists and science interns with the fundamental knowledge of the experimental aspects and state-of-the-art technology for vesicular carriers to equip their rational application in tumor targeting, but also provides a holistic understanding of regulatory concerns, patents, and clinical trials. In 15 chapters. this book provides basics and advances in stimuli-responsive vesicular carriers for tumor targeting based on findings outlined in highly organized tables, illustrative figures, and flow charts.With a focus on the extrapolation of bioengineering tools in the domain of vesicular carriers, stimuli-responsive features concerning tumors, drug delivery approaches, and associated challenges, it helps readers to define the major gaps in knowledge that can lead to significant scientific discoveries in therapy, diagnosis, and theragnosis of cancer.

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