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Elsevier

Books in Life sciences

  • Advances in Cancer Research

    • 1st Edition
    • Volume 138
    • English
    Advances in Cancer Research, Volume 138, the latest release in this ongoing, well-regarded serial provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents original reviews on research bridging oncology and gene expression, with this volume covering unconventional approaches to modulating the immunogenicity of tumor cells, tumor dormancy and immunoediting, the emerging role of anti-apoptotic Bcl-2 family proteins in chemoresistance, Beclin-1 and autophagy, MDA-7/IL-24, and nanotechnology and medicine.

  • Pet-to-Man Travelling Staphylococci

    A World in Progress
    • 1st Edition
    • Vincenzo Savini
    • English
    Pet-to-Man Travelling Staphylococci: A World in Progress explores Staphylococci, a dangerous pathogen that affects both humans and animals with a wide range of infection states. This bacteria can spread rapidly as a commensal organism in both humans and pets, and is an agent of disease. Staphylococci are potentially highly virulent pathogens which require urgent medical attention. In addition, Staphylococci remain a threat within hospital environments, where they can quickly spread across a patient population. This book explores the organisms' resistance to many compounds used to treat them, treatment failure and multidrug resistant staphylococci, amongst other related topics.

  • Fundamentals of Cognitive Neuroscience

    A Beginner's Guide
    • 2nd Edition
    • Nicole M. Gage + 1 more
    • English
    Fundamentals of Cognitive Neuroscience: A Beginner's Guide, Second Edition, is a comprehensive, yet accessible, beginner’s guide on cognitive neuroscience. This text takes a distinctive, commonsense approach to help newcomers easily learn the basics of how the brain functions when we learn, act, feel, speak and socialize. This updated edition includes contents and features that are both academically rigorous and engaging, including a step-by-step introduction to the visible brain, colorful brain illustrations, and new chapters on emerging topics in cognition research, including emotion, sleep and disorders of consciousness, and discussions of novel findings that highlight cognitive neuroscience’s practical applications. Written by two leading experts in the field and thoroughly updated, this book remains an indispensable introduction to the study of cognition.

  • Ovarian Cycle

    • 1st Edition
    • Volume 107
    • Gerald Litwack
    • English
    Ovarian Cycle, Volume 107, the latest in the Vitamins and Hormones series first published in 1943, and the longest-running serial published by Academic Press, covers the latest updates on hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms. This latest release includes an overview of the ovarian cycle, a section on ovarian hyperstimulation syndrome, information on androgens and ovarian follicular maturation, information on peptide inhibitors of human thymidylate synthase to inhibit ovarian cancer cell growth, sections on nodal and luteolysis, neurokinins, dynorphin and pulsatile Lh secretion, Lh receptor expression by Mir12, and gonadotrophin-surge attenuating factor, melatonin and Bmp-6 regulation, amongst other topics.

  • Register for Recording Purchases and Supplies of Dangerous Drugs

    • 1st Edition
    • Sam Stuart
    • English
    Register for Recording Purchases and Supplies of Dangerous Drugs is a list of registration forms for use by qualified medical practitioners, dentists, veterinarians, who can possess, supply or prepare dangerous drugs in exercise of their professions. This compilation of registration forms includes extracts from regulations made under the Dangerous Drugs Act, 1920 outlining the withdrawal of authority of an authorized person from by the Secretary of State. This book defines the form of prescription, the provisions as to dispensing of prescriptions, and the keeping of records in the register. This book also requires the authorized practitioners to preserve documents such as all registers, records, books, or prescriptions, as well as lists the preparations exempted from the regulations. These exempted preparations include Pasta Arsenicalis, B.P.C. 1934, Pil. Ipecac. c. Scila, B.P.C. 1934, Pulv. Cretae Aromat. C. Opio, B.P. 1932. The practitioner should scan and consult medical journals from time to time for any announcement of changes in the list of exempted drugs. This book lists forms for purchases and supplies for various drugs such as morphine, diamorphine, cocaine, medicinal opium, Indian hemp, Eucodal, Dicodide, Dilaudide, Desomorphine, and Pethidine. This book is intended for the use of physicians, surgeons, dentists, and veterinarians. It can also benefit pharmacists and pharmacologists.

  • Psychopharmacology in Family Practice

    • 1st Edition
    • David Wheatley
    • English
    Psychopharmacology in Family Practice discusses the concept of psychopharmacology in the context of family practice. The book is an account of the group of studies done by the author’s group regarding the various concerns in psychopharmacology. The text covers the rationale, organization, and methodology. Next, the book deals with the placebo response. The next two chapters discuss the drugs in anxiety and depression, respectively. Chapter Six discusses the alternative ideas for treating anxiety and depression, such as the use of non-psychotropic drugs. Chapter Seven describes the factors that influence response, while Chapter Eight deals with psychosomatic pharmacotherapy. The next two chapters tackle the side-effects and transcultural aspects, respectively. The closing chapter presents the summary of the conclusions of the studies. The book will be of great use to psychiatric researchers and practitioners. It can also benefit psychologists.

  • The Analysis of Biological Materials

    The Proceedings of a Conference Held in Pretoria, South Africa, October 1977, by the Spectroscopic Society of South Africa
    • 1st Edition
    • L. R. P. Butler
    • English
    The Analysis of Biological Materials: The Proceedings of a Conference Held in Pretoria, South Africa October 1977 by the Spectroscopic Society of South Africa focuses on the applications, processes, and methodologies involved in the analysis of biological materials. The compilation first offers information on the contributions of the analysis of biological materials in medical diagnosis and treatment and development of atomic absorption spectroscopic techniques in biological analysis. Topics include applications of biological tissues analysis in medical research; physics and chemistry in medicine; complexing characteristics and in vivo roles of metals; and metals in the treatment of disease. The book then takes a look at microprobe analysis of pathological tissues, including specimen preparation and microprobe analysis investigation. The publication discusses the application of ion microprobe mass analyzer to the analysis of biological materials; multi-element analysis of teeth and other biological materials by instrumental neutron activation; and single column gradient elution ion exchange amino acid analyzer. The text also examines biographical materials of oceanographic origin and volatile metals in biological materials. The compilation is a dependable reference for readers interested in the analysis of biological materials.

  • Case Studies in Public Health

    • 1st Edition
    • Theodore H. Tulchinsky
    • English
    Case Studies in Public Health contains selected case studies of some of the most important and influential moments in medicine and epidemiology. The cases chosen for this collection represent a wide array of public health issues that go into the makeup of what can be termed the New Public Health (NPH), which includes traditional public health, such as sanitation, hygiene and infectious disease control, but widens its perspective to include the organization, financing and quality of health care services in a much broader sense. Each case study is presented in a systematic fashion to facilitate learning, with the case, background, current relevance, economic issues, ethical issues, conclusions, recommendation and references discussed for each case. The book is a valuable resource for advanced students and researchers with specialized knowledge who need further information on the general background and history of public health and important scientific discoveries within the field. It is an ideal resource for students in public health, epidemiology, medicine, anthropology, and sociology, and for those interested in how to apply lessons from the past to present and future research.

  • Viruses

    Molecular Biology, Host Interactions, and Applications to Biotechnology
    • 1st Edition
    • Paula Tennant + 2 more
    • English
    Viruses: Molecular Biology, Host Interactions, and Applications to Biotechnology provides an up-to-date introduction to human, animal and plant viruses within the context of recent advances in high-throughput sequencing that have demonstrated that viruses are vastly greater and more diverse than previously recognized. It covers discoveries such as the Mimivirus and its virophage which have stimulated new discussions on the definition of viruses, their place in the current view, and their inherent and derived ‘interactomics’ as defined by the molecules and the processes by which virus gene products interact with themselves and their host’s cellular gene products. Further, the book includes perspectives on basic aspects of virology, including the structure of viruses, the organization of their genomes, and basic strategies in replication and expression, emphasizing the diversity and versatility of viruses, how they cause disease and how their hosts react to such disease, and exploring developments in the field of host-microbe interactions in recent years. The book is likely to appeal, and be useful, to a wide audience that includes students, academics and researchers studying the molecular biology and applications of viruses

  • Advances in Parasitology

    • 1st Edition
    • Volume 99
    • English
    Advances in Parasitology, Volume 99, the latest in a series first published in 1963, contains comprehensive and up-to-date reviews on all areas of interest in contemporary parasitology. The series includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy, and life history, which help to shape current thinking and applications. This new release includes sections on climate change and NTDs, Leprosy, parasite cultures, molecular epidemiology of Anisakis and anisakiasis, evolution in triatomine vectors of Chagas disease, expanding the vector control toolbox for Malaria elimination, and parasites of the giant panda.

  • Alternative and Replacement Foods

    • 1st Edition
    • Volume 17
    • Alexandru Mihai Grumezescu + 1 more
    • English
    Alternative and Replacement Foods, Volume 17, a volume in the Handbook of Food Bioengineering series, presents the most up-to-date research on synthetic and replacement food components for scientists and researchers. The book helps them understand the significant impact of these foods on the length and quality of life of consumers. It presents a solid resource that brings together multidisciplinary research and its relationship to various disciplines. Readers will find a broad range of potential outcomes discussed, such as food safety, human and animal health benefits, and the development of new and novel foods through the bio-fortification of nutrients in foods.

  • Organoids and Mini-Organs

    • 1st Edition
    • Jamie A. Davies + 1 more
    • English
    Organs and Mini-Organs combines contributions from leading practitioners who work under the editorial control of an acclaimed researcher who also served for eight years as Editor-in-Chief of the journal Organogenesis, the first journal on this topic. The book begins with an introduction, but then delves into chapters that present advice on how to make organoids for many systems. In addition, case studies that illustrate the uses of organioids are presented, along with discussions on future directions and specific problems that need to be solved.

  • Rehabilitation Robotics

    Technology and Application
    • 1st Edition
    • Roberto Colombo + 1 more
    • English
    Rehabilitation Robotics gives an introduction and overview of all areas of rehabilitation robotics, perfect for anyone new to the field. It also summarizes available robot technologies and their application to different pathologies for skilled researchers and clinicians. The editors have been involved in the development and application of robotic devices for neurorehabilitation for more than 15 years. This experience using several commercial devices for robotic rehabilitation has enabled them to develop the know-how and expertise necessary to guide those seeking comprehensive understanding of this topic. Each chapter is written by an expert in the respective field, pulling in perspectives from both engineers and clinicians to present a multi-disciplinary view. The book targets the implementation of efficient robot strategies to facilitate the re-acquisition of motor skills. This technology incorporates the outcomes of behavioral studies on motor learning and its neural correlates into the design, implementation and validation of robot agents that behave as ‘optimal’ trainers, efficiently exploiting the structure and plasticity of the human sensorimotor systems. In this context, human-robot interaction plays a paramount role, at both the physical and cognitive level, toward achieving a symbiotic interaction where the human body and the robot can benefit from each other’s dynamics.

  • Physiology of the Gastrointestinal Tract

    • 6th Edition
    • Hamid M. Said
    • English
    Physiology of the Gastrointestinal Tract, Sixth Edition, a Two-Volume set, covers the study of the mechanical, physical and biochemical functions of the GI Tract by linking clinical disease and disorder, thus bridging the gap between clinical and laboratory medicine while also covering breakthroughs in gastroenterology, such as the brain-gut axis and microbiome. Additionally, information is provided at the organism level, including animal models of gastrointestinal disorders and therapeutic possibilities. The book covers a wide range of conditions, from food allergies, constipation, chronic liver disease and IBS, also exploring emerging techniques to diagnose and normalize functions of the GI tract. As a highly referenced book, this is a useful resource for gastroenterologists, physiologists, internists, professional researchers and instructors teaching courses for clinical and research students.

  • Metabolic Aspects of Aging

    • 1st Edition
    • Volume 155
    • English
    Metabolic Aspects of Aging, Volume 155, the latest release in the Progress in Molecular Biology and Translational Science series seeks to provide the most topical, informative and exciting monographs available on a wide variety of research topics related to prions, viruses, bacteria and eukaryotes. The series includes in-depth knowledge on the molecular, biological aspects of organismal physiology and function, with this release including chapters on Longevity, Metabolic Disease and Community Health, the Metabolic Aspects of Aging, Obesity, Metabolism, and Aging: A Multiscalar Approach, The Intersection of Curandismo and Western Medicine and Their Epidemiological Impact for Aging Mexican Americans, and more.

  • The Parietal Lobe

    • 1st Edition
    • Volume 151
    • English
    The Parietal Lobe, Volume 151, the latest release from the Handbook of Clinical Neurology series, provides a foundation on the neuroanatomy, neurophysiology and clinical neurology/neuropsych... of the parietal lobe that is not only applicable to both basic researchers and clinicians, but also to students and specialists who are interested in learning more about disorders brought on by damage or dysfunction. Topics encompass the evolution, anatomy, connections, and neurophysiology, the major neurological and neuropsychological deficits and syndromes caused by damage, the potential for improvement via transcranial stimulation, and the role of the parietal in the cerebral networks for perception and action.

  • Mechanisms of DNA Recombination and Genome Rearrangements: Intersection Between Homologous Recombination, DNA Replication and DNA Repair

    • 1st Edition
    • Volume 601
    • English
    Mechanisms of DNA Recombination and Genome Rearrangements: Intersection between Homologous Recombination, DNA Replication and DNA Repair, Volume 601, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Homologous genetic recombination remains the most enigmatic process in DNA metabolism. The molecular machines of recombination preserve the integrity of the genetic material in all organisms and generate genetic diversity in evolution. The same molecular machines that support genetic integrity by orchestrating accurate repair of the most deleterious DNA lesions, however, also promote survival of cancerous cells and emergence of radiation and chemotherapy resistance. This two-volume set offers a comprehensive set of cutting edge methods to study various aspects of homologous recombination and cellular processes that utilize the enzymatic machinery of recombination. The chapters are written by the leading researches and cover a broad range of topics from the basic molecular mechanisms of recombinational proteins and enzymes to emerging cellular techniques and drug discovery efforts.

  • Omics Technologies and Bio-engineering

    Volume 2: Towards Improving Quality of Life
    • 1st Edition
    • Debmalya Barh + 1 more
    • English
    Omics Technologies and Bio-Engineering: Towards Improving Quality of Life, Volume 2 is a unique reference that brings together multiple perspectives on omics research, providing in-depth analysis and insights from an international team of authors. The book delivers pivotal information that will inform and improve medical and biological research by helping readers gain more direct access to analytic data, an increased understanding on data evaluation, and a comprehensive picture on how to use omics data in molecular biology, biotechnology and human health care.

  • Brain Banking

    • 1st Edition
    • Volume 150
    • English
    Brain Banking, Volume 150, serves as the only book on the market offering comprehensive coverage of the functional realities of brain banking. It focuses on brain donor recruitment strategies, brain bank networks, ethical issues, brain dissection/tissue processing/tissue dissemination, neuropathological diagnosis, brain donor data, and techniques in brain tissue analysis. In accordance with massive initiatives, such as BRAIN and the EU Human Brain Project, abnormalities and potential therapeutic targets of neurological and psychiatric disorders need to be validated in human brain tissue, thus requiring substantial numbers of well characterized human brains of high tissue quality with neurological and psychiatric diseases.

  • Quality and Safety in Neurosurgery

    • 1st Edition
    • Daniel J. Guillaume + 1 more
    • English
    Quality and Safety in Neurosurgery covers recent improvements and presents solutions for problems that impact patient care. This book is written for anyone who works at the intersection of quality, safety and neurosurgery, including neurosurgeons, neurologists, clinical researchers looking to improve outcomes in neurosurgery, hospital quality and safety officers, department leaders, fellows and residents. Edited by neurosurgeons who helped build the culture of quality and safety in the Department of Neurosurgery at UMN, this work emphasizes quality and safety, whether through ‘value based purchasing’, finding specialty specific quality and safety metrics, or just the professional desire to provide quality care.

  • Nanoemulsions

    Formulation, Applications, and Characterization
    • 1st Edition
    • Seid Mahdi Jafari + 1 more
    • English
    Nanoemulsions: Formulation, Applications, and Characterization provides detailed information on the production, application and characterization of food nanoemulsion as presented by experts who share a wealth of experience. Those involved in the nutraceutical, pharmaceutical and cosmetic industries will find this a useful reference as it addresses findings related to different preparation and formulation methods of nanoemulsions and their application in different fields and products. As the last decade has seen a major shift from conventional emulsification processes towards nanoemulsions that both increase the efficiency and stability of emulsions and improve targeted drug and nutraceutical delivery, this book is a timely resource.

  • Nutrition Conference for Feed Manufacturers

    University of Nottingham, Volume 8
    • 1st Edition
    • Henry Swan + 1 more
    • English
    Nutrition Conference for Feed Manufacturers: 8 is a collection of papers that discusses world protein supplies, protein nutrition of farm livestock, alternative sources of protein, problems of amino- acid availability, and the use of synthetic amino-acids. Several papers deal with non-protein nitrogen as an alternative nitrogen source, the nutritive value of silages, and the use of dried grass or processed straw in ruminant feeding. One paper evaluates the protein and amino-acid requirements of poultry, pigs, and ruminants. Another paper examines the reduced availability of amino-acid in some batches of feeding stuffs and notes that the problem has been approached by correcting low estimates and the adoption of improved manufacturing practices. One paper points out the possibility of producing all the amino acids required for feedstock either synthetically or by fermentation, but the animal feed industry will be interested only in methionine and lysine. The paper also notes that France can save almost a quarter of its protein imports by adopting a generalized use of lysine and a better use of methionine. The collection will prove valuable to agriculturists, food technologists, bio-chemists, veterinarians, economists, livestock owners, and scientists involved in livestock food production or research.

  • The Mind in Disease

    Some Conditions Cured by Suggestion
    • 4th Edition
    • M. P. Leahy
    • English
    The Mind in Disease: Some Conditions Cured by Suggestion, Fourth Impression emphasizes that a hopeful mental outlook can do much to improve a patient's condition in disease, whether the disease itself is physical or mental. This book stresses that the mind is a factor in disease and acts sometimes by virtue of willpower or at other times by virtue of the imagination. By combining imagination and willpower, suggestion can be developed to cure many diseases. The topics discussed include the relationship between patient and doctor in suggestion treatment; physical pain, and how suggestion acts in the relief of it; chronic constipation cured by an impression made on the mind; and depression in a German prisoners of war camp, 1915. This publication is suitable for psychiatrists and medical practitioners interested in suggestion treatment.

  • Individual Differences in Sensory and Consumer Science

    Experimentation, Analysis and Interpretation
    • 1st Edition
    • Tormod Næs + 2 more
    • English
    Individual Differences in Sensory and Consumer Science: Experimentation, Analysis and Interpretation presents easily readable, state-of-the-art coverage on how to plan and execute experiments that give rise to individual differences, also providing the framework for successful analysis and interpretation of results. The book highlights the different methodologies that can be applied and how to select the correct methodology based on the type of study you are performing, be it product research and development, quality control or consumer acceptance studies. Written by an experienced team of statisticians and sensory and consumer scientists, the book provides both academics and industry professionals with the first complete overview of a topic of ever-increasing importance.

  • Equitable Access to High-Cost Pharmaceuticals

    • 1st Edition
    • Zaheer-Ud-Din Babar
    • English
    Equitable Access to High-Cost Pharmaceuticals seeks to aid the development and implementation of equitable public health policies by pharmaco-economics professionals, health economists, and policymakers. With detailed country-by country analysis of policy and regulation, the Work compares and contrasts national healthcare systems to support researchers and practitioners identify optimal healthcare policy solutions. The Work incorporates chapters on global regulatory changes, health technology assessment guidelines, and competitive effectiveness research recommendations from international bodies such as the OECD or the EU. Novel policies such as horizon scanning, managed-entry agreement and post-launch monitoring are considered in detail. The Work also thoroughly reviews novel pharmaceuticals with particular research interest, including cancer drugs, orphan medicines, Hep C, and personalized medicines.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 84
    • English
    Advances in Clinical Chemistry, Volume 84, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry. It is the benchmark for novel analytical approaches in the clinical laboratory.

  • The Evolution of Molecular Biology

    The Search for the Secrets of Life
    • 1st Edition
    • Kensal Van Holde + 1 more
    • English
    The Evolution of Molecular Biology: The Search for the Secrets of Life provides the historical knowledge behind techniques founded in molecular biology, also presenting an appreciation of how, and by whom, these discoveries were made. It deals with the evolution of intellectual concepts in the context of active research in an approachable language that accommodates readers from a variety of backgrounds. Each chapter contains a prologue and epilogue to create continuity and provide a complete framework of molecular biology. This foundational work also functions as a historical and conceptual supplement to many related courses in biochemistry, biology, chemistry, genetics and history of science. In addition, the book demonstrates how the roots of discovery and advances–and an individual’s own research–have grown out of the history of the field, presenting a more complete understanding and context for scientific discovery.

  • New and Future Developments in Microbial Biotechnology and Bioengineering

    Crop Improvement through Microbial Biotechnology
    • 1st Edition
    • Ram Prasad + 2 more
    • English
    Crop Improvement through Microbial Biotechnology explains how certain techniques can be used to manipulate plant growth and development, focusing on the cross-kingdom transfer of genes to incorporate novel phenotypes in plants, including the utilization of microbes at every step, from cloning and characterization, to the production of a genetically engineered plant. This book covers microbial biotechnology in sustainable agriculture, aiming to improve crop productivity under stress conditions. It includes sections on genes encoding avirulence factors of bacteria and fungi, viral coat proteins of plant viruses, chitinase from fungi, virulence factors from nematodes and mycoplasma, insecticidal toxins from Bacillus thuringiensis, and herbicide tolerance enzymes from bacteria.

  • New Research and Developments of Water-Soluble Vitamins

    • 1st Edition
    • Volume 83
    • English
    New Research and Developments of Water-Soluble Vitamins, Volume 83, provides updated knowledge about nutrients in foods and how to avoid their deficiency, especially for those essential nutrients that should be present in the diet to reduce disease risk and optimize health. The book provides the latest advances on the identification and characterization of emerging bioactive compounds with putative health benefits. With up-to-date information on food science, including raw materials, production, processing, distribution and consumption, it is an ideal resource for nutritionists and researchers alike.

  • Cell Fate in Mammalian Development

    • 1st Edition
    • Volume 128
    • English
    Cell Fate in Mammalian Development, Volume 128, the latest release in the Current Topics in Developmental Biology series, provides reviews on cell fate in mammalian development. Each chapter is written by an international board of authors, with this release including sections on the Specification of extra-embryonic lineages during mouse pre-implantation development, Cell polarity and fate specification, The circuitry that drives trophectoderm identity, Breaking symmetry and the dynamics of transcription factors directing cell fate specification, Mechanics and cell fate, How physical properties of cells change in development and their effect on cell fate decisions, and more.

  • Understanding Climate Change Impacts on Crop Productivity and Water Balance

    • 1st Edition
    • S. K. Jalota + 3 more
    • English
    Understanding Climate Change Impacts on Crop Productivity and Water examines the greenhouse gas emissions and their warming effect, climate change projections, crop productivity and water. The book explores the most important greenhouse gases that influence the climate system, technical terms associated with climate projections, and the different mechanisms impacting crop productivity and water balance. Adaptive and mitigative strategies are proposed to cope with negative effects of climate change in particular domains. This book will help researchers interested in climate change impacts on the atmosphere, soil and plants.

  • The Microbiology of Central Nervous System Infections

    • 1st Edition
    • Volume 3
    • English
    The Microbiology of Central Nervous System Infections, Volume 3, discusses modern approaches to the diagnosis, treatment and prophylaxis of central nervous system (CNS) infections. This new release is divided into five sections that cover treatment strategies, imaging, molecular diagnosis, management of CNS infections with metal nanoparticles, and prophylaxis of CNS infections, including bacterial, viral and fungal infections. The last section contains a chapter on transmissible spongiform encephalopathies and modern trends in its diagnosis and treatment. University teachers, medical practitioners, graduate and postgraduate students, researchers in microbiology, and those in the pharmaceutical and laboratory diagnostic industries will find the book very important.

  • Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination

    • 1st Edition
    • Volume 600
    • English
    Mechanisms of DNA Recombination and Genome Rearrangements: Methods to Study Homologous Recombination, Volume 600, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Homologous genetic recombination remains the most enigmatic process in DNA metabolism. The molecular machines of recombination preserve the integrity of the genetic material in all organisms and generate genetic diversity in evolution. The same molecular machines that support genetic integrity by orchestrating accurate repair of the most deleterious DNA lesions, however, also promote survival of cancerous cells and emergence of radiation and chemotherapy resistance. This two-volume set offers a comprehensive set of cutting edge methods to study various aspects of homologous recombination and cellular processes that utilize the enzymatic machinery of recombination The chapters are written by the leading researches and cover a broad range of topics from the basic molecular mechanisms of recombinational proteins and enzymes to emerging cellular techniques and drug discovery efforts.

  • Protein-Protein Interactions in Human Disease, Part B

    • 1st Edition
    • Volume 111
    • English
    Protein-Protein Interactions in Human Disease, Volume 111, Part B, promotes further research and development in the protein interaction network in order to identify critical proteins involved in the etiology of human diseases and locate new protein targets for drug development. Thus, this volume is of considerable interest to protein chemists, pharmacologists, cell biologists, immunologists, structural biologists, computational biochemists and other researchers working in the field. In addition, these articles would be of great benefit to medical, biology and pharmacology students who specialize in this field.

  • Systems Biology and Its Application in TCM Formulas Research

    • 1st Edition
    • Weidong Zhang
    • English
    Systems Biology and Its Application in TCM Formulas Research presents a theoretical research system formed for Traditional Chinese Medicine (TCM) formulas, along with information on the study of Shexiang Baoxin Pill (SBP), a TCM formula that has shown significant clinical efficacy in the treatment of cardiovascular diseases. The content combines theory and practice, and includes guidance for both theoretical concepts and operable technical routes. This is a valuable source not only for biomedical researchers involved in Systems Biology studies, but also for students and scientists interested in learning more about Traditional Chinese Medicine and its applications in contemporary medicine.

  • Precision Medicine

    Tools and Quantitative Approaches
    • 1st Edition
    • Hans-Peter Deigner + 1 more
    • English
    Precision Medicine: Tools and Quantitative Approaches discusses precision and personalized medicine, two relevant topics that are revolutionizing diagnostics and treatment, while also providing a shift toward prevention. The book covers the most relevant features and explanations underlying developments in the field. A timely review on prerequisites, causes and consequences is given. Unique to this book is a combined view on technical and data analysis aspects that is mandatory for obtaining and interpreting results. This book is a valuable source for researchers in medical and life sciences, physicians and students with an interest in this emerging field of precision medicine.

  • Advances in Immunology

    • 1st Edition
    • Volume 137
    • English
    Advances in Immunology, Volume 137, the latest in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this release including sections on Notch and T-Cell signaling/T-Cell memory, Single Cell Analysis of CD8+ and CD4+ T Cell Differentiation, New Developments in the Chemokine Field, the Role of Caveolin-1 in BCR and TCR Receptors, The Unusual Biochemistry of Bovine Immunoglobulins, and the Molecular Aspects of Allergens and Allergy.

  • A Comprehensive Guide to the Prostate

    Eastern and Western Approaches for Management of BPH
    • 1st Edition
    • Bilal Chughtai
    • English
    A Comprehensive Guide to the Prostate: Eastern and Western Approaches for Management of BPH provides a multidisciplinary approach to BPH and male voiding dysfunction, presenting comprehensive guidance on management. With an equal focus on traditional, complementary and alternative medicine, and a look at novel technologies, a complete understanding of the BPH disease process is revealed. Abstracts and references in every chapter make the connection between research and practice. Perfect for researchers and urologists, this must-have reference provides what is needed to understand BPH and male voiding dysfunction.

  • Advances in Agronomy

    • 1st Edition
    • Volume 148
    • English
    Advances in Agronomy continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial.

  • Transgenic Plants and Beyond

    • 1st Edition
    • Volume 86
    • English
    Transgenic Plants, Volume 86, the latest release in the series Advances in Botanical Research, brings together information needed by many teachers, researchers and managers who have to consider biotechnology from a scientific or legal point-of-view. It presents authors who bring their long personal experience on a given subject. Although the subjects are technical in nature, the take-home message of each chapter is understandable by non-specialists.

  • Food Control and Biosecurity

    • 1st Edition
    • Volume 16
    • Alexandru Mihai Grumezescu + 1 more
    • English
    Food Control and Biosecurity, Volume Sixteen, the latest release in the Handbook of Food Bioengineering series, is an essential resource for anyone in the food industry who needs to understand safety and quality control to prevent or reduce the spread of foodborne diseases. The book covers information from exporter to transporter, importer and retailer, and offers valuable tools to measure food quality while also addressing government standards and regulations for food production, processing and consumption. The book presents cutting-edge methods for detecting hazardous compounds within foods, including carcinogenic chemicals. Other related topics addressing food insecurity and food defense are also discussed.

  • ODE/PDE α-synuclein Models for Parkinson’s Disease

    • 1st Edition
    • William E. Schiesser
    • English
    ODE/PDE Alpha-Synuclein Models for Parkinson’s Disease discusses a mechanism for the evolution of Parkinson’s Disease (PD) based on the dynamics of the protein α-synuclein, a monomer that has been implicated in this disease. Specifically, α-synuclein morphs and aggregates into a polymer that can interfere with functioning neurons and lead to neurodegenerative pathology. This book first demonstrates computer-based implementation of a prototype ODE/PDE model for the dynamics of the α-synuclein monomer and polymer, and then details the methodology for the numerical integration of ODE/PDE systems which can be applied to computer-based analyses of alternative models based on the reader's interest. This book facilitates immediate computer use for research without the necessity to first learn the basic concepts of numerical analysis for ODE/PDEs and programming algorithms

  • Food Process Engineering and Technology

    • 3rd Edition
    • Zeki Berk
    • English
    Food Process Engineering and Technology, Third Edition combines scientific depth with practical usefulness, creating a tool for graduate students and practicing food engineers, technologists and researchers looking for the latest information on transformation and preservation processes and process control and plant hygiene topics. This fully updated edition provides recent research and developments in the area, features sections on elements of food plant design, an introductory section on the elements of classical fluid mechanics, a section on non-thermal processes, and recent technologies, such as freeze concentration, osmotic dehydration, and active packaging that are discussed in detail.

  • Forensic Ecogenomics

    The Application of Microbial Ecology Analyses in Forensic Contexts
    • 1st Edition
    • T. Komang Ralebitso-Senior
    • English
    Forensic Ecogenomics: The Application of Microbial Ecology Analyses in Forensic Contexts provides intelligence on important topics, including environmental sample provenance, how to indicate the body decomposition timeline to support postmortem interval (PMI) and postmortem submersion interval (PMSI) estimates, and how to enhance identification of clandestine and transit grave locations. A diverse group of international experts have come together to present a clear perspective of forensic ecogenomics that encapsulates cutting-edge, topical and relevant cross-disciplinary approaches vital to the field.

  • Type 2 Diabetes and Dementia

    • 1st Edition
    • Velandai Srikanth + 1 more
    • English
    Type 2 Diabetes and Dementia details the relationship between diabetes, dementia and the future of medicine and therapeutics. Chapters range from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment and prevention strategies, and the application of therapeutics. The book reflects the translational aspects of the current science in the field, with an emphasis on the display of neuroimaging and neuropathology. It contains contributions from world experts, and is ideal for clinicians and researchers in the fields of neurology, neuroscience, geriatric medicine and endocrinology.

  • Atlas of the Developing Rat Nervous System

    • 4th Edition
    • George Paxinos + 1 more
    • English
    Paxinos and Ashwell's Atlas of the Developing Rat Nervous System, Fourth Edition, builds on the many excellent features of previous editions that have made this book the most cited atlas of the developing rat brain. It provides the most comprehensive depiction of not only the structures in the brain and spinal cord, but also of the peripheral nervous system and target organs that are important for developmental neurobiologists, allowing the user to follow neural structures through the developing embryo in both time and space. The nomenclature and identification of structures in this edition have been thoroughly updated to ensure accuracy and compatibility.

  • Cardiovascular Outcomes of Treatments available for Patients with Type 1 and 2 Diabetes, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 47-1
    • Guillermo E. Umpierrez
    • English
    This issue of Endocrinology and Metabolism Clinics, edited by Dr. Guillermo E. Umpierrez, will focus on Cardiovascular Outcomes of Treatments available for Patients with Type 1 and 2 Diabetes. Topics include--but are not limited to--Diabetes and CAD and PVD; Prediabetes and CVD- DM prevention; Pathogenesis of atherosclerosis/CVD in diabetes Intensive Diabetes Treatment and CV Outcomes in T1D; Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes, Diabetes and Stroke; Cardiovascular outcome trials of glucose-lowering drugs or strategies in type 2 diabetes; Heart Failure in Diabetes Mellitus; Individualizing Glucose Lowering Therapy in the Patient with Diabetes and Heart Disease; Managing Dyslipidemia in Type 2 Diabetes; Blood pressure control and cardiovascular and renal outcomes; Hyperglycemia in acute coronary syndromes; Hospital Glucose Control; Managing Diabetes and cardiovascular risk in chronic kidney disease; and more.

  • Calcium Movement in Excitable Cells

    Pergamon Studies in The Life Sciences
    • 1st Edition
    • P. F. Baker + 1 more
    • English
    Calcium Movement in Excitable Cells, which is a second in a series, is a collection of articles taken from articles published in Progress in Biophysics and Molecular Biology, just like the first. The monograph is divided into two chapters. Chapter 1, Transport and Metabolism of Calcium Ions in Nerve, tackles the mechanisms responsible for maintaining the electrochemical gradient for calcium and effecting changes for the permeability of the cell membrane to calcium ions. Chapter 2, Divalent Cations as Charge Carriers in Excitable Membranes, tries to find out if divalent cations such as calcium, barium, and strontium can permeate excitable membranes. With two in-depth studies about movement of calcium as well as other cations and the factors behind it, the text is recommended to medical doctors, biologists, and biochemists who wish to learn more about this phenomenon.

  • Understanding Cancer from a Systems Biology Point of View

    From Observation to Theory and Back
    • 1st Edition
    • Irina Kareva
    • English
    Understanding Cancer from a Systems Biology Point of View: From Observation to Theory and Back starts with a basic question, why do we sometimes observe accelerated metastatic growth after resection of primary tumors? Next, it helps readers understand the systemic nature of cancer and how it affects treatment approaches and decisions. The book puts together aspects of cancer that many readers have most likely never combined, using unfamiliar, novel methods. It is a valuable resource for cancer researchers, cancer biologists, mathematicians and members of the biomedical field who are interested in applying systems biology methodologies for understanding and treating cancer.

  • Food Crop Production by Smallholder Farmers in Southern Africa

    Challenges and Opportunities for Improvement
    • 1st Edition
    • Ambayeba Muimba-Kankolongo
    • English
    Food Crop Production by Smallholder Farmers in Southern Africa: Challenges and Opportunities for Improvement evaluates traditional cultivation practices used by smallholder farmers, providing a synthesis of the latest information on increasing crop yield through adoption of research innovations. The book catalogs smallholder cultivation practices and recommends innovative strategies for improving the agriculture sector including: management practices that reduce net carbon emissions; technologies that improve soil structures and conserve the natural resources base; means of empowering female resources along value chains; and government commitment to adopt policies that enhance agriculture productivity by encouraging farmers to use environmentally sound cultivation technologies. Traditional farming techniques often produce negative impacts on the environment and ecosystem resulting in outbreaks of diseases and pests. In addition to the region’s recurrent droughts, these outbreaks of numerous diseases and pests, weeds and other invasive plants put thousands at risk of poverty and hunger, as well as malnutrition. This book presents enhanced agricultural production technologies for ensuring adequate food production, safety and nutritional quality for the population of Southern Africa and forms the basis for an increased SADC regional effort in food production through which financial and trade institutions can improve stakeholder capacities, encourage micro-enterprise development and enhance employment and regional trade.

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