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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • The Pediatric Cerebellum, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 26-3
    • Thierry A. G. M. Huisman + 1 more
    • English
    This issue of Neuroimaging Clinics of North America focuses on The Pediatric Cerebellum, and is edited by Drs. Huisman and Andrea Poretti. Articles will include: The role of the pediatric cerebellum in motor functions, neurocognition and behavior: a clinical perspective; Normal development of the cerebellum: from the fetus to the adolescent; Cerebellar malformations; Cerebellar disruptions; Metabolic disorders with cerebellar involvement; Neurocutaenous syndromes with cerebellar involvement; Vascular disorders of the cerebellum; Tumors of the cerebellum; Infectious and inflammatory diseases of the cerebellum; Cerebro-cerebellar network, and more!

  • Neuroimaging, Part I

    • 1st Edition
    • Volume 135
    • English
    Neuroimaging, Part One, a text from The Handbook of Clinical Neurology illustrates how neuroimaging is rapidly expanding its reach and applications in clinical neurology. It is an ideal resource for anyone interested in the study of the nervous system, and is useful to both beginners in various related fields and to specialists who want to update or refresh their knowledge base on neuroimaging. This first volume specifically covers a description of imaging techniques used in the adult brain, aiming to bring a comprehensive view of the field of neuroimaging to a varying audience. It brings broad coverage of the topic using many color images to illustrate key points. Contributions from leading global experts are collated, providing the broadest view of neuroimaging as it currently stands. For a number of neurological disorders, imaging is not only critical for diagnosis, but also for monitoring the effect of therapies, and the entire field is moving from curing diseases to preventing them. Most of the information contained in this volume reflects the newness of this approach, pointing to this new horizon in the study of neurological disorders.

  • Trace Amines and Neurological Disorders

    Potential Mechanisms and Risk Factors
    • 1st Edition
    • Tahira Farooqui + 1 more
    • English
    Trace Amines and Neurological Disorders: Potential Mechanisms and Risk Factors explores trace amines which, under normal conditions, are present in the mammalian brain and peripheral nervous tissues at very low (nanomolar) concentrations. However, in a diverse array of human pathologies ranging from substance abuse, depression, attention deficit hyperactivity disorder, eating disorders, schizophrenia, and other neurological and neuropsychiatric diseases, the levels of trace amines are unusually high with an imbalance in their functions. Furthermore, the rapid turnover of trace amines is evidenced by their dramatic increases following treatment with monoamine oxidase inhibitors (MAOI) or deletion of the MAO genes. This suggests that the concentration of trace amines may be considerably higher at neuronal synapses than predicted by steady-state measures, implicating some pathophysiological role. Therefore, understanding molecular mechanisms and developing selective agonists and antagonists for trace amine-associated receptors (TAARs) has become a good approach for treating these diseases. Although the effects of trace amines at low physiological concentrations in mammalian species have been difficult to demonstrate, they may serve to maintain the neuronal activity of other monoamine neurotransmitters by possessing postsynaptic modulatory effects, particularly dopamine and serotonin, within defined physiological limits. Such an effect of trace amines makes them ideal candidates for the development of novel therapeutics for a wide range of human disorders. This book presents up-to-date, cutting-edge, and comprehensive information on the link between trace amines and neurological disorders.

  • Neuroimaging, Part II

    • 1st Edition
    • Volume 136
    • English
    Neuroimaging, Part Two, a volume in The Handbook of Clinical Neurology series, illustrates how neuroimaging is rapidly expanding its reach and applications in clinical neurology. It is an ideal resource for anyone interested in the study of the nervous system, and is useful to both beginners in various related fields and to specialists who want to update or refresh their knowledge base on neuroimaging. This second volume covers imaging of the adult spine and peripheral nervous system, as well as pediatric neuroimaging. In addition, it provides an overview of the differential diagnosis of the most common imaging findings, such as ring enhancement on MRI, and a review of the indications for imaging in the most frequent neurological syndromes. The volume concludes with a review of neuroimaging in experimental animals and how it relates to neuropathology. It brings broad coverage of the topic using many color images to illustrate key points. Contributions from leading global experts are collated, providing the broadest view of neuroimaging as it currently stands. For a number of neurological disorders, imaging is not only critical for diagnosis, but also for monitoring the effect of therapies, with the entire field moving from curing diseases to preventing them. Most of the information contained in this volume reflects the newness of this approach, pointing to the new horizon in the study of neurological disorders.

  • The Neurobiology of Schizophrenia

    • 1st Edition
    • Ted Abel + 1 more
    • English
    The Neurobiology of Schizophrenia begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance.

  • Astrocytes and Epilepsy

    • 1st Edition
    • Jacqueline A. Hubbard + 1 more
    • English
    Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory". Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of astrocytes, star-shaped glial cells in the brain, to neuronal and network excitability and seizure activity. Furthermore, many important cellular and molecular changes occur in astrocytes in epileptic tissue in both humans and animal models of epilepsy. The goal of Astrocytes and Epilepsy is to comprehensively review exciting findings linking changes in astrocytes to functional changes responsible for epilepsy for the first time in book format. These insights into astrocyte contribution to seizure susceptibility indicate that astrocytes may represent an important new therapeutic target in the control of epilepsy. Astrocytes and Epilepsy includes background explanatory text on astrocyte morphology and physiology, epilepsy models and syndromes, and evidence from both human tissue studies and animal models linking functional changes in astrocytes to epilepsy. Beautifully labelled diagrams are presented and relevant figures from the literature are reproduced to elucidate key findings and concepts in this rapidly emerging field. Astrocytes and Epilepsy is written for neuroscientists, epilepsy researchers, astrocyte investigators as well as neurologists and other specialists caring for patients with epilepsy.

  • Electrophysiology and Microinjection

    • 1st Edition
    • Volume 4
    • P. Michael Conn
    • English
    Electrical activity is central to the functioning and nature of neural cells. Every effort has been made in this volume to provide representative examples of useful techniques that have made this area a productive component of the neurosciences.

  • Methods in Neurosciences

    Quantitative and Qualitative Microscopy
    • 1st Edition
    • Volume 3
    • P. Michael Conn
    • English
    Because of the significance of morphology and cellular communication unique to the functioning and interdependence of neural systems, many of the advances in the neurosciences rely on classic as well as new microscopy techniques.

  • L'enfant dyspraxique et les apprentissages

    Coordonner les actions thérapeutiques et scolaires
    • 2nd Edition
    • Michèle Mazeau + 2 more
    • French
    Au sein des « dys- », les dyspraxies sont des troubles du développement gestuel et/ou visuo-spatial dont les répercussions sociales et scolaires peuvent être sévères, envahissant le quotidien et compromettant l’avenir. Ces pathologies ont en effet de graves conséquences sur l’ensemble des apprentissages.L’ouv... par des cliniciennes dont la pratique auprès de jeunes dyspraxiques s’inscrit dans l’indispensable interaction quotidienne entre rééducation et école, cet ouvrage vise à fournir des clés pour comprendre les ressorts cachés de ces échecs scolaires, afin de mieux les prévenir ou tout au moins les pallier. C’est pourquoi sont abordés ici à la fois les stratégies de remédiation (dévolues aux rééducateurs) et les aménagements qui, dans le même temps, doivent prendre place en classe, en partenariat avec les enseignants. Comportant de nombreux exemples qui illustrent les difficultés rencontrées tous les jours par ces enfants, ce livre constitue un ensemble cohérent de propositions pratiques et concrètes visant à rétablir les chances de réussite scolaire et d’épanouissement du jeune dyspraxique.Cet ouvrage permet non seulement de comprendre la spécificité des processus en jeu dans les apprentissages du jeune dyspraxique (gestuels, scolaires ou rééducatifs), mais il constitue un outil de terrain précieux pour assurer la réussite scolaire et l’épanouissement du jeune dyspraxique. Les auteures précisent les conditions d’un véritable projet thérapeutique global, avant d’aborder les différents aspects des accompagnements dans les apprentissages : écrire, e-écrire, compter, lire. Puis un chapitre de synthèse offre une méthode générale d’analyse des supports scolaires, spécifiquement dans les aspects qui croisent et sollicitent le handicap de l’élève. Enfin, sont abordées les difficultés liées à la vie quotidienne (repas, habillage, sports et loisirs) et leurs répercussions sur l’estime de soi. Cette nouvelle édition propose une révision de l’ensemble des données et une refonte complète des chapitres dédiés aux supports pédagogiques et à l’informatique qui ont considérablement évolué.

  • The Mathematical Brain Across the Lifespan

    • 1st Edition
    • Volume 227
    • English
    The Mathematical Brain Across the Lifespan is the latest volume in the Progress in Brain Research series that focuses on new trends and developments. This established international series examines major areas of basic and clinical research within the neurosciences, as well as popular and emerging subfields.

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