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Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Animal and Translational Models for CNS Drug Discovery: Neurological Disorders

    • 1st Edition
    • Robert A. McArthur + 1 more
    • English
    Neurological Disorders is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for neurological disorders such as neurofibromatosis, Alzheimer’s disease, Parkinson’s disease, Huntington disease, ALS, and the epilepsies. Neurological Disorders has introductory chapters expressing the view of the role and relevance of animal models for drug discovery and development for the treatment of psychiatric disorders from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in each therapeutic area covered and discuss the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This is the second volume in the three volume-set, Animal and Translational Models for CNS Drug Discovery 978-0-12-373861-5, which is also available for purchase individually.
  • Concise Learning and Memory

    The Editor's Selection
    • 1st Edition
    • John H. Byrne
    • English
    The study of learning and memory is a central topic in neuroscience and psychology. Many of the basic research findings are directly applicable in the treatment of diseases and aging phenomena, and have found their way into educational theory and praxis.Concise Learning and Memory represents the best 30 chapters from Learning and Memory: A comprehensive reference (Academic Press March 2008), the most comprehensive source of information about learning and memory ever assembled, selected by one of the most respective scientists in the field, John H. Byrne. This concise version provides a truly authoritative collection of overview articles representing fundamental reviews of our knowledge of this central cognitive function of animal brains. It will be an affordable and accessible reference for scientists and students in all areas of neuroscience and psychology. There is no other single-volume reference with such authority and comprehensive coverage and depth currently available.
  • Serotonin-Dopamine Interaction: Experimental Evidence and Therapeutic Relevance

    • 1st Edition
    • Volume 172
    • Giuseppe Di Giovanni + 2 more
    • English
    This book provides a unique and timely multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and behavioral data of the serotonin (5-HT)-dopamine (DA) interactions. Central serotonergic and dopaminergic systems play a critical role in the regulation of normal and abnormal behaviors. Moreover, recent evidence suggests that the dysfunction of the DA and 5-HT neurotransmitter systems contribute to various mental disorders including depression, schizophrenia, drug addiction and Parkinson’s disease. This extremely important topic is of wide interest within the scientific community, with relevance not only to specialists but also to general practitioners and students. The book provides a valuable contribution to the debate on new pharmacological approaches for several psychopathological states, with contributions from expert neuroscientists and pharmacologists who comprehensively survey the most significant currently active areas of dopamine/serotonin interactions.
  • Neuropsychologie du vieillissement normal et pathologique

    • 1st Edition
    • Kathy Dujardin + 1 more
    • French
    Dans nos sociétés modernes, le nombre de personnes âgées ne cesse de croître, et certaines d'entre elles voient leurs fonctions cognitives décliner au point de perdre leur autonomie physique, psychique et sociale. Élucider les mécanismes de ce déclin pour permettre un diagnostic précoce constitue un défi pour de nombreuses équipes de recherche. Fruit de la contribution de chercheurs et d'universitaires du monde francophone, cet ouvrage a pour objectif d'aborder le vieillissement cognitif normal et pathologique, à la fois sous l'angle des neurosciences et de la psychologie cognitive. Les premiers chapitres proposent une synthèse des éléments d'épidémiologie et de neurobiologie indispensables à la compréhension de l'évolution liée à l'âge des fonctions cérébrales. Une mise au point des connaissances actuelles en matière de vieillissement cognitif permet ensuite de mieux cerner l'impact du vieillissement sur les grandes fonctions cognitives, avant d'étudier les différentes pathologies du vieillissement s'accompagnant d'un déclin cognitif (maladie d'Alzheimer, démences vasculaires, démences frontotemporales, syndromes parkinsoniens). La notion de « mild cognitive impairment » (ou trouble cognitif léger) est largement développée à travers l'analyse d'études récentes. Cette approche est complétée par des procédures d'évaluation des fonctions cognitives ainsi que par des perspectives de traitement (pharmacologique, rééducation, …).
  • Epilepsy in Women

    The Scientific Basis for Clinical Management
    • 1st Edition
    • Volume 83
    • Barry Gidal + 1 more
    • English
    This volume guides the practitioner in the current management of women with epilepsy, in a comprehensive and scientifically informed manner. Many chapters are devoted to the various aspects of pregnancy management for women with epilepsy, from reducing the risks of medication exposure to breast feeding. All female age groups are discussed and chapters on issues important for adolescents and the mature women are also included. The editors have included internationally recognized experts as contributors, to bring together a body of knowledge unparalleled in previous settings. This book should be a guide to management for women with epilepsy for years to come, due to its solid scientific basis and the comprehensive vision of the contributors.
  • Puzzling Cases of Epilepsy

    • 2nd Edition
    • Dieter Schmidt + 1 more
    • English
    Epilepsy is one of the most common neurological disorders, and original observations in the field are often the key to diagnosis and successful treatment. Physicians new to the field as well as seasoned practitioners will benefit from more than one hundred case vignettes that explore the universe of epilepsy as it presents in daily practice. Some of these cases challenge long-held views about epilepsy and others bring the reader to the limits of our understanding of epilepsy, both in clinical and basic science. To improve the interface of clinical and basic science in epilepsy, basic scientists comment on the potential mechanisms underlying clinical observations, and clinicians assess the potential impact of recent results of experiments in the laboratory. Puzzling Cases of Epilepsy highlights the importance that original observations have in inspiring both new treatments and continued research.
  • Handbook of Episodic Memory

    • 1st Edition
    • Volume 18
    • Ekrem Dere + 3 more
    • English
    Episodic memory is the name of the kind of memory that records personal experiences instead of the mere remembering of impersonal facts and rules. This type of memory is extremely sensitive to ageing and disease so an understanding of the mechanisms of episodic memory might lead to the development of therapies suited to improve memory in some patient populations. Episodic memory is unique in that it includes an aspect of self-awareness and helps us to remember who we are in terms of what we did and what we have been passed through and what we should do in the future. This book brings together a renowned team of contributors from the fields of cognitive psychology, neuropsychology and behavioural and molecular neuroscience. It provides a detailed and comprehensive overview of recent developments in understanding human episodic memory and animal episodic-like memory in terms of concepts, methods, mechanisms, neurobiology and pathology. The work presented within this book will have a profound effect on the direction that future research in this topic will take.
  • Using Eye Movements as an Experimental Probe of Brain Function

    A Symposium in Honor of Jean Büttner-Ennever
    • 1st Edition
    • Volume 171
    • R. John Leigh + 1 more
    • English
    This volume of Progress in Brain Research is based on the proceedings of a conference, "Using Eye Movements as an Experimental Probe of Brain Function," held at the Charing Cross Hospital Campus of Imperial College London, UK on 5th -6th December, 2007 to honor Professor Jean Büttner-Ennever. With 87 contributions from international experts – both basic scientists and clinicians – the volume provides many examples of how eye movements can be used to address a broad range of research questions. Section 1 focuses on extraocular muscle, highlighting new concepts of proprioceptive control that involve even the cerebral cortex. Section 2 comprises structural, physiological, pharmacological, and computational aspects of brainstem mechanisms, and illustrates implications for disorders as diverse as opsoclonus, and congenital scoliosis with gaze palsy. Section 3 addresses how the cerebellum transforms neural signals into motor commands, and how disease of such mechanisms may lead to ataxia and disorders such as oculopalatal tremor. Section 4 deals with sensory-motor processing of visual, vestibular, somatosensory, and auditory inputs, such as are required for navigation, and gait. Section 5 illustrates how eye movements, used in conjunction with single-unit electrophysiology, functional imaging, transcranial magnetic stimulation, and lesion studies have illuminated cognitive processes, including memory, prediction, and even free will. Section 6 includes 18 papers dealing with disorders ranging from congenital to acquired forms of nystagmus, genetic and degenerative neurological disorders, and treatments for nystagmus and motion sickness.
  • The Prefrontal Cortex

    • 4th Edition
    • Joaquin Fuster
    • Joaquin Fuster
    • English
    This is the fourth edition of the undisputed classic on the prefrontal cortex, the principal "executive" structure of the brain. Because of its role in such cognitive functions as working memory, planning, and decision-making, the prefrontal cortex is critically involved in the organization of behavior, language, and reasoning. Prefrontal dysfunction lies at the foundation of several psychotic and neurodegenerative disorders, including schizophrenia and dementia.
  • Advances in the Study of Behavior

    • 1st Edition
    • Volume 38
    • H. Jane Brockmann + 5 more
    • English
    Advances in the Study of Behavior was initiated over 40 years ago to serve the increasing number of scientists engaged in the study of animal behavior. That number is still expanding. This volume makes another important "contribution to the development of the field" by presenting theoretical ideas and research to those studying animal behavior and to their colleagues in neighboring fields. Advances in the Study of Behavior is now available online at ScienceDirect — full-text online from volume 30 onward.