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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Biophysical Aspects of Cerebral Circulation

    • 1st Edition
    • Yu. E. Moskalenko + 2 more
    • English
    Biophysical Aspects of Cerebral Circulation provides a comprehensive review of the cerebral circulatory system. This book consists of four chapters. Chapter 1 is devoted to methodology attempts to explain the special features of a biophysical approach. The biophysical principles of the most commonly used modem methods such as the clearance method and rheoencephalography are described in detail. The second and third chapters examine all the biophysical aspects of the cerebral circulatory system as a functional unit and deal with some principles of its regulation. The results of systems analysis using mathematical modeling are presented in broad outline. Chapter 4 deals with processes related to the regional cerebral circulation. Such investigations focus mainly on the relationship between periodically fluctuating factors affecting limited areas of brain tissue. This text is beneficial to medical students and individuals researching on cerebral circulation.

  • Neurological Emergencies

    • 1st Edition
    • S.D. Shorvon
    • English
    Neurological Emergencies presents a comprehensive guide on the initial assessment and early treatment of patients with neurological emergencies. It discusses the diagnosis, emergency investigations, and handling of coma patients. It addresses the management of focal supratentorial lesion. Some of the topics covered in the book are the diffuse neurological or systemic disturbance; emergency resuscitation; diagnosis and treatment of transtentorial herniation; diagnosis and treatment of acute viral encephalitis; raised intracranial pressure; diagnosis and treatment of non-viral infective encephalitis; viral meningitis; meningovascular syphilis; diagnosis and treatment of cerebral abscess; diagnosis and treatment of intracranial subdural empyema; and diagnosis and treatment of cerebral venous thrombosis. The diagnosis and treatment ofstroke is fully covered. An in-depth account of the difference between haemorrhage and infarction is provided. The diagnosis of subarachnoid haemorrhage is completely presented. A chapter is devoted to the prevention of more cranial bleeding.

  • Neurogenic Heart Lesions

    • 1st Edition
    • I. S. Zavodskaya + 2 more
    • English
    Neurogenic Heart Lesions reviews the main publications concerned with the problem of neurogenic lesions of the heart. The book describes the methods for producing experimental neurogenic lesions, as well as the pharmacological analysis of the participation of the sympathetic nervous system and its transmitters in the development of neurogenic lesions of the myocardium. The text also discusses the changes in energy metabolism and in functional conditions of the myocardium caused by neurogenic lesions; and the pharmacoprophylaxis and pharmacotherapy of the biochemical changes produced by neurogenic lesions of the myocardium. Pharmacologists, pathologists, and other clinicians and physicians concerned with the new achievements in the field of cardiology will find the book invaluable.

  • Antipsychotic Drugs and Their Side-Effects

    • 1st Edition
    • Thomas R.E. Barnes
    • English
    In line with other volumes in the Neuroscience Perspectives Series, this volume covers the background, pharmacology, molecular biology, and biochemistry of antipsychotic drugs, together with an overview assessment of the therapeutic considerations. Over the past 40 years, the effectiveness of conventional neuroleptic agents for psychotic illness has been offset by a wide range of adverse side-effects, including motor side-effects like parkinsonism. Studies show that lowering doses may still produce the antipsychotic effect while lessening the risk of side-effects. As all available antispychotic drugs are able to block dopamine, specifically D2 receptors, doses below the threshold level for producing acute motor disorder can still be therapeutically effective. With the identification and characterization of multiple dopamine receptors, the possibility of more selective drugs with better side-effect potential has arisen. Other novel antipsychotic agents include D1 receptor blockers, partial dopamine agonists and non-dopamine drugs such as 5-HT receptor blockers, sigma receptor antagonists and NMDA receptor agonists. This volume reviews both the basic science of the conventional and atypical neuroleptics and their present and potential therapeutic use.

  • The Catecholamines in Psychiatric and Neurologic Disorders

    • 1st Edition
    • C. Raymond Lake + 1 more
    • English
    The Catecholamines in Psychiatric and Neurologic Disorders focuses on the contributions of catecholamines (CA) in the modulation of blood pressure, stress and exercise, body movements, memory, learning, emotions, thought processing, appetite, and mediation of psychotropic drug action. The selection first elaborates on the techniques for the assessment and interpretation of catecholamine measurements in neuropsychiatric patients and catecholaminergic response to stress and exercise. Discussions focus on noradrenergic response to isometric exercise, isotonic exercise, effect of acceleration on sympathetic activity, techniques for sympathetic nervous system evaluation, and measurements of CA and their metabolites in cerebrospinal fluid. The text then takes a look at urinary CA in behavioral research on stress; CA in anxiety disorders and mitral valve prolapse; and interaction with neurotransmitters in normal subjects and in patients with selected neurologic diseases. The selection examines noradrenergic responses in postural hypotension, norepinephrine, alcohol, and alcoholism, and catecholamine metabolism in anorexia nervosa. Topics include cerebral catecholamine metabolism in anorexia nervosa; central nervous system norepinephrine and voluntary alcohol drinking; and overview of norepinephrine in selected pediatric disorders. The book is a dependable reference for neuropsychiatrists and readers interested in the contributions of catecholamines on psychiatric disorders.

  • Neurobiology of Steroids

    • 1st Edition
    • Volume 22
    • P. Michael Conn + 1 more
    • English
    Steroid hormones are unique compounds in that they are active at the interface of peripheral endocrine events and neural mechanisms. Thus their effects present an important peripheral signaling system to alter brain function. This volume presents state-of-the-art and classical techniques for the study of steroid hormones and their receptors and their effects and actions.

  • Case Presentations in Neurology

    • 1st Edition
    • G. S. Venables + 2 more
    • English
    Case Presentations in Neurology presents a selection of case histories demonstrating how patients with often quite simple problems may present and to bring out aspects of their diagnosis and management. All the patients presented to the Department of Neurology including those with more obscure diagnoses. The book consists of 12 exercises, each of six cases broadly corresponding to the style of the MRCP (UK) written case history papers. Each case is set out with the history and physical findings given first. There follows either a series of questions or true/false statements on one side of the page which the reader should attempt before continuing on to the answer section on the other side. There then follows a short discussion about each case and a single reference. This book is intended for those doctors studying for higher professional qualifications such as the MRCP, although it may be of interest and use to medical students approaching their final examinations.

  • Clinical Anesthesia in Neurosurgery

    • 1st Edition
    • Elizabeth A. M. Frost
    • English
    Clinical Anesthesia in Neurosurgery, Second Edition, integrates the evolution of the field of neuroanesthesia with the major areas of neurosurgical activity to give the reader the required perspective and requisite information to help in laying the foundation for future advances as well as describing the current state of the art. The book contains 25 chapters organized into five parts. Part I presents studies on cerebral physiology and evaluation. Topics covered include cerebral circulation and metabolism, intraoperative neurophysiologic monitoring, and central nervous system effects of anesthetic agents. Part II covers neurosurgical and related procedures, such as posterior cranial fossa surgery, surgery of the spine, and peripheral nerve surgery. Part III examines central nervous system trauma including spinal cord trauma and cardiovascular effects of severe head injury. Part IV takes up postoperative and intensive care, including postanesthetic care, neurosurgical intensive care, and parenteral nutrition while Part V deals with the medical criteria and legal aspects of brain death.

  • Intensive Care for Neurological Trauma and Disease

    • 1st Edition
    • Barth A. Green + 2 more
    • English
    Intensive Care for Neurological Trauma and Disease presents the progress in intensive care in terms of technological development on life-support and monitoring systems. This book discusses the ideal neurologic intensive care environment that is based on developments in other specialized care units. Organized into 24 chapters, this book begins with an overview of the problem of neurological trauma. This text then presents the accident scene management protocol for acute spinal cord injury as a standard to other forms of trauma system pre-hospital care. Other chapters consider the appropriate drugs and dosages for the management of status epilepticus in the newborn and older children. This book discusses as well the findings on the neurological examination and provides a framework for an etiological classification that has direct therapeutic implications. The final chapter deals with the clinical aspects, diagnosis, and management of neuromuscular diseases. This book is a valuable resource for clinicians and intensive care unit nurses.

  • The Release of Catecholamines from Adrenergic Neurons

    • 1st Edition
    • David M. Paton
    • English
    The Release of Catecholamines from Adrenergic Neurons covers the advances in understanding the mechanism of catecholamine release and other neurotransmitters from adrenergic neurons. This book is organized into four sections encompassing 18 chapters. The opening section surveys biochemical studies of the mechanism and regulation of nerve stimulation. This section examines the role of calcium, prostaglandins, and presynaptic adrenoceptors and muscarine receptors in catecholamine release. The next section describes the modification of catecholamine release by several drugs, including adrenergic neuron blocking agents, narcotic analgesics, opioid peptides, lysergic acid diethylamide, anesthetics, alcohols, and adenosine and adenine nucleotides. These topics are followed by discussions of catecholamine release induced by cations and other drugs, such as nicotinic agonists, calcium ionophores, veratridine, scorption venom, and phenethylamines. The final section deals with the biochemical assessment of peripheral adrenergic activity and the clinical pharmacology of adrenergic neuron blocking agents. This book is intended for pharmacologists, neurologists, researchers, and advanced students.

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