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Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

BooksJournals

  • Pulsatility in Neuroendocrine Systems

    • 1st Edition
    • Volume 20
    • P. Michael Conn + 1 more
    • English
    Pulsatility is now recognized as a nearly ubiquitous functional feature of neuroendocrine systems. This volume presents a comprehensive guide to the established and emerging technologies being used to study the perplexing phenomenon of pulsatility. Molecular, cellular, physiological, and mathematical approaches are described in detail.

  • Antipsychotic Drugs and Their Side-Effects

    • 1st Edition
    • Thomas R.E. Barnes
    • English
    In line with other volumes in the Neuroscience Perspectives Series, this volume covers the background, pharmacology, molecular biology, and biochemistry of antipsychotic drugs, together with an overview assessment of the therapeutic considerations. Over the past 40 years, the effectiveness of conventional neuroleptic agents for psychotic illness has been offset by a wide range of adverse side-effects, including motor side-effects like parkinsonism. Studies show that lowering doses may still produce the antipsychotic effect while lessening the risk of side-effects. As all available antispychotic drugs are able to block dopamine, specifically D2 receptors, doses below the threshold level for producing acute motor disorder can still be therapeutically effective. With the identification and characterization of multiple dopamine receptors, the possibility of more selective drugs with better side-effect potential has arisen. Other novel antipsychotic agents include D1 receptor blockers, partial dopamine agonists and non-dopamine drugs such as 5-HT receptor blockers, sigma receptor antagonists and NMDA receptor agonists. This volume reviews both the basic science of the conventional and atypical neuroleptics and their present and potential therapeutic use.

  • Neurotoxins

    • 1st Edition
    • Volume 8
    • P. Michael Conn
    • English
    The exquisite simplicity and potency of toxins have made them valuable probes of neural systems. This book presents a comprehensive compilation of techniques used for the preparation, handling, and, particularly, for the use of neurotoxins. Model systems are described in which these neurotoxins have been extremely valuable in developing an understanding of the cellular and molecular basis of secretion and electrophysiological events leading to altered cell function.

  • Ion Channels of Excitable Cells

    • 1st Edition
    • Volume 19
    • P. Michael Conn + 1 more
    • English
    Because of the highly significant and widely recognized roles of ion channels in physiology, pathophysiology, pharmacology, and toxicology, the term ion channel has now become a household word in the biomedical sciences. This volume covers preparations and techniques for the study of various ion channels. Both voltage-gated and ligand-gated ion channels of neurons, axons, and cardiac and smooth muscles are covered. It includes not only patch clamp techniques but molecular biology and imaging techniques as well.

  • Interlimb Coordination

    Neural, Dynamical, and Cognitive Constraints
    • 1st Edition
    • Stephan P. Swinnen + 3 more
    • English
    This comprehensive edited treatise discusses the neurological, physiological, and cognitive aspects of interlimb coordination. It is unique in promoting a multidisciplinary perspective through introductory chapter contributions from experts in the neurosciences, experimental and developmental psychology, and kinesiology. Beginning with chapters defining the neural basis of interlimb coordination in animals, the book progresses toward an understanding of human locomotor control and coordination and the underlying brain structures and nerves that make such control possible. Section two focuses on the dynamics of interlimb coordination and the physics of movement. The final section presents information on how practice and experience affect coordination, including general skill acquisition, learning to walk, and the process involved in rhythmic tapping.

  • Biological Aspects of Affective Disorders

    • 1st Edition
    • Volume 1
    • R.W. Horton
    • English
    Biological research in the affective disorders has been an international growth industry for several years. Biological Aspects of Affective Disorders is a comprehensive introduction to the biochemical, pharmacological, and genetic aspects constituting the abnormalities that may underline the diseases of depression and mania, together with the current understanding of the clinical features and management of affected patients.It will be of great value especially to young researchers from all disciplines contributing to this area and to trainee psychiatrists.

  • Providing Pharmacological Access to the Brain

    Alternate Approaches
    • 1st Edition
    • Volume 21
    • Thomas R. Flanagan + 1 more
    • English
    This volume focuses on contemporary approaches for delivering experimental and therapeutic agents into the brain. The contributions provide methodological details that are typically not available in the literature. Subtleties and shortcuts critical to each procedure are included to facilitate their use by both the experienced researcher and novice.

  • Quantitative and Qualitative Microscopy

    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 3: Quantitative and Qualitative Microscopy is a collection of papers that deals with microscopic techniques in statistical measures. This volume describes microscopy using sophisticated stains and dyes to advance observation of tests and experiments. Section I describes autoradiography including micro chemical methods, high-resolution autoradiography, and single- or double-label quantitative autoradiography for use in imaging of brain activity patterns or determining cerebral physiology. Section II discusses the quantification of structures through statistical and computational methods including dynamic video imaging technology. Section III explains the use of tracers, toxins, or dyes in tracing neuronal connections. One paper addresses the use of small injections of axonally transported fluorescent tracers. Section IV explains staining technology such as using the silver impregnation method for frozen sections of human nervous tissue that are gathered from tissues preserved in formalin. Section V addresses freezing techniques and those using freeze-fracture methods in neurobiology. The text also discusses cryoprotection and other freezing methods to control ice crystals found in fixed or unfixed brain tissues. Section VI presents the combined and high-resolution methods in polarization microscopy and microscopic investigations. Cellular biologists, micro-chemists, and scientific researchers in the field of micro- and cellular biology will appreciate this book.

  • Cognitive Development

    The Child's Acquisition of Diagonality
    • 1st Edition
    • David R. Olson
    • David S. Palermo
    • English
    Cognitive Development: The Child's Acquisition of Diagonality is an empirical and rational enquiry into the child's development of a conceptual system relating to the concept of the diagonal during the age range three to six years. A detailed examination will be made of why a young child has difficulty with such a problem, and what occurs during development that removes this difficulty. In the context of these empirical arguments, the book considers such theoretical questions as the nature of intellectual skills and conceptual or symbolic knowledge, as well as the role of experience and instruction in their development. The study concludes with a description of the child's reconstruction of the diagonal in terms of what at least poses as a general model of perceptual and intellectual development, and accounts for, among other things, man's increasing ability to apprehend and theorize about the motion of the stars. It shows that it is the elaboration of the child's perceptual knowledge in the context of his performatory attempts in such cultural media as language and geometry that accounts for his ability to copy a diagonal in particular and his intellectual development in general.

  • Neurobiology and Behavior

    • 1st Edition
    • A. O. Dennis Willows
    • English
    The Mollusca, Volume 8: Neurobiology and Behavior, Part 1, provides an overview of the state of knowledge in molluscan neurobiology and behavior. It is part of a multivolume treatise that covers the areas of structure and function, metabolic biochemistry, molecular biomechanics, environmental biochemistry, physiology, ecology, reproduction and development, neurobiology and behavior, and evolution. The Mollusca is intended to serve a range of disciplines—zoology, biochemistry, physiology, and paleontology. It will prove useful to researchers and to all others with interests in molluscs. The book contains four chapters and begins with a chapter on the behavior of gastropod mollusks. Subsequent chapters deal with learning in gastropod mollusks, the neuronal control of behavior in gastropods, and the development and plasticity of molluscan neurons.

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