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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Epigenetics in Health and Disease part B

      • 1st Edition
      • Volume 198
      • May 23, 2023
      • English
      • Hardback
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      • eBook
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      Epigenetics in Health and Disease, Volume 198 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on Computational biology in epigenetics, Artificial intelligence and machine learning in epigenetics, CRISPR-dCas9 Systems for Epigenetic Editing for Therapeutic Applications, Epigenetics in heredity disease, Epigenetics in cancer development, diagnosis and therapy, Microbiota and epigenetics: health impact, Histone deacetylase (HDACs) Inhibitors: Clinical applications, Early epigenetic markers for precision medicine, Epigenetics of neurological diseases, Epigenetic Regulons in Alzheimer’s disease, and Epigenetics in epilepsy.
    • Circadian System

      • 1st Edition
      • Volume 137
      • September 11, 2023
      • Rossen Donev
      • English
      • Hardback
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      • eBook
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      Circadian System, Volume 137 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters that comprehensively cover Circadian Systems Genes and Their Importance for Human Health, Single nucleotide polymorphisms (SNPs) in circadian genes: Impact on Gene Function and Phenotype, Relationship between circadian rhythm and diseases: sex hormones impact, Advances in circadian clock regulation of reproduction, Disruption of the clock gene expression in central and peripheral circadian oscillators by maternal overnutrition in the Oryctolagus cuniculus, COVID-19 disease management in aspect of Circadian system, and more. Other sections cover Molecular Characterization of Circadian Gene Expression and Its Correlation with Survival Percentage in Colorectal Cancer Patients, Identifying circadian gene signature that estimates overall survival from colon adenocarcinoma, The role of environmental signals in the expression of rhythmic cardiac proteins and their influence on cardiac pathologies, and much more.
    • Encyclopedia of Biodiversity

      • 3rd Edition
      • November 3, 2023
      • Samuel M. Scheiner
      • English
      • Hardback
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      • eBook
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      Encyclopedia of Biodiversity, Third Edition, Seven Volume Set provides a coherent, synthetic and comprehensive overview of the field, bringing together contributions from over 400 expert academics and practitioners. The book brings together the dimensions of biodiversity and examines the services it provides and measures to protect it. Major themes include the evolution of biodiversity, systems for classifying and defining biodiversity, ecological patterns and theories of biodiversity, and an assessment of contemporary patterns and trends in biodiversity. The entire work is reviewed and updated, including new chapters on topics which have come to the forefront since the publication of the previous edition.The science of biodiversity has become the science of our future. It is an interdisciplinary field spanning areas of both physical and life sciences. Our awareness of the loss of biodiversity has brought a long overdue appreciation of the magnitude of this loss and a determination to develop the tools to protect our future. One important feature of the new edition will be updated information on the growing biodiversity crisis.
    • Modifications and targeting of protein termini Part B

      • 1st Edition
      • Volume 686
      • July 25, 2023
      • English
      • Hardback
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      • eBook
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      Modifications and Targeting of Protein Termini, Part B, Volume 686 in the Methods in Enzymology serial, highlights new advances in the field with this new volume presenting interesting chapters on a variety of timely topics, including In vitro production of N-degron fused proteins and its application, Identification of N-degrons and N-recognins using peptide pull-downs combined with quantitative mass spectrometry-based proteomics, Monitoring ADO-dependent proteolysis in cells using fluorescent reporter proteins, Monitoring the interactions between N-degrons and N-recognins of the Arg/N-degron pathway, Characterization and chemical modulation of p62/SQSTM1/Sequestos... as an autophagic N-recognin of the Arg/N-degron pathway. Other chapters cover Analysis of higher plant N-degron pathway components and substrates via expression in S. cerevisiae, Building libraries to dissect terminal degrons with fluorescent timers, Affinity isolation and biochemical characterization of N-degron ligands using the N-recognin, ClpS, Probing the effects of N-terminal acetylation on α-synuclein structure, aggregation and toxicity, Increasing the coverage of the N-terminome with Lys-N Amino Terminal enrichment (LATE), and more.
    • Receptor Endocytosis and Signalling in Health and Disease - Part B

      • 1st Edition
      • Volume 196
      • February 20, 2023
      • English
      • Hardback
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      • eBook
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      Receptor Endocytosis and Signalling in Health and Disease, Part B, Volume 196 highlights the different aspects of receptor endocytosis and signaling, covering several receptors which are associated with different organs and that play a key role in normal functioning in the body, including somatostatin, Mas receptor, AMPA, Dopamine, 5-HT1-2, GABA, GPCR, nuclear receptor, Integrin, BCR, CRHR1, etc. Chapters in this new release include Internalization of somatostatin receptors in brain and periphery, Mas receptor, signaling and trafficking in health and disease, Endocytosis of AMPA receptors: Role in neurological conditions, Endocytosis of dopamine receptor: Signaling in brain, and more. Additional chapters cover Endocytosis of LXRs: Signalling in liver, Endocytosis of LDL receptor: Importance in cardiovascular diseases, Advances in the molecular level understanding of G-protein-coupled receptor, Nuclear receptor: Structure and function, Integrin receptor trafficking in health and disease, B Cell Receptor (BCR) endocytosis,CRHR1 endocytosis: Spatiotemporal regulation of receptor signaling, and much more.
    • Ionizing Radiation and the Immune Response - Part A

      • 1st Edition
      • Volume 376
      • March 29, 2023
      • English
      • Hardback
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      • eBook
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      Ionizing Radiation and the Immune Response, Volume 376, Part A reviews the latest updates on the immune response induced by ionizing radiations. Sections discuss NK functions in radio-induced immune response, TRT and immune response, Radio-induced immune response and lipid metabolism, Effect of protons and heavy ions on immune response, Effect of flashtherapy and mini beam on immune response, Radio-induced lymphopenia, CT to potentiate radio-induced immune response, Impact of RT on healthy tissues (inflammation), Radio-induced macrophagic response, To use nanoparticles and ionizing radiations to modulate immune response: opinion of the chemist, biologist and clinician, and more. Additional sections touch on the Effect of low dose radiation on radio-induced immune response, Role of Dendritic cells in radiation-induced immune response, Relationship between the tumor microenvironment and the efficacy of the radiotherapy/immunot... combination+A23, and Biomarkers of radiation induced response to optimize radio-immunotherapy combination.
    • Control of Cell Cycle and Cell Proliferation

      • 1st Edition
      • Volume 135
      • April 11, 2023
      • Rossen Donev
      • English
      • Hardback
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      • eBook
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      Control of Cell Cycle and Cell Proliferation, Volume 135 in the Advances in Protein Chemistry and Structural Biology series, presents chapters on a variety topics, including Exploiting pivotal mechanisms behind the senescence-like cell cycle arrest, Viral infection on through Cell Cycle Regulation, Analyzing drug resistant mutation in CDK4 gene and identification of potential inhibitors through structure based virtual screening approach, Controlling cell proliferation by targeting CDK6 using drug repurposing approach, The role of the nucleolus in regulating cell cycle, Chromatin regulators in DNA replication and genome stability maintenance during S-phase, Role of macrophage in cancer cell progression and targeted immunotherapies, and much more.
    • Mitochondria and Bacterial Pathogens - Part A

      • 1st Edition
      • Volume 374
      • February 24, 2023
      • English
      • Hardback
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      • eBook
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      Mitochondria and Bacterial Pathogens, Volume 374, Part A. Mitochondria control various processes that are integral to cellular and organismal homeostasis, including Ca2+ fluxes, bioenergetic metabolism, and cell death. Perhaps not surprisingly, multiple pathogenic bacteria have evolved strategies to subvert mitochondrial functions in support of their survival and dissemination. In the IRCMB volume 375, the authors discus different pathogenic mechanisms that converge on the ability of bacteria to control the mitochondrial compartment of host cells.
    • Stem Cell in Medicine

      • 1st Edition
      • Volume 199
      • August 31, 2023
      • English
      • Hardback
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      **Association of American Publishers (AAP) PROSE Award Finalist in Biomedicine and Neuroscience, 2024**Stem Cells in Medicine, Volume 199 in the Progress in Molecular Biology and Translational Science series, provides the most topical and informative research in the field of stem cells. Sections in this new release update on an Introduction to stem cells, Stem cell engineering, Xeno-free culture and proliferation of hPSCs on 2D biomaterials, 3D scaffold preparation for stem cell culture and differentiation, GMP grade production of hPSCs, Human hepatic stem cell assay, Cardiomyocyte cell sheets derived from hPSCs and muscle cells for myocardial infarction treatment, Stem cell therapy for osteoarthritis, hPSC-derived RPE transplantation for the treatment of macular degeneration, and much more.The book provides not only fundamental aspects and cultural and production methods of stem cells, but also the critical engineering aspects of stem cells such as drug screening using hepatocytes and disease treatment by transplantation of retinal pigment epithelium and cardiomyocytes which are derived from human pluripotent stem cells.
    • Advances in Microbial Physiology

      • 1st Edition
      • Volume 82
      • March 20, 2023
      • English
      • Hardback
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      • eBook
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      Advances in Microbial Physiology, Volume 82 in this serial that highlights new advances in the field, presents interesting chapters on a variety of topics, including Protein secretion via the Type I secretion system, Purine utilization by enterobacteria, Microbiology of Algae, Growth of enteric bacteria in the intestine on C4DCs: Governance of C4DC transporters in metabolic adaptation and genetic control, Biological functions of bacterial lysophospholipids, and much more.