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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Cellular, Molecular, and Environmental Contribution in Cardiac Remodeling

      • 1st Edition
      • April 16, 2024
      • Asim K. Duttaroy + 1 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 9 5 7 0 2
      • eBook
        9 7 8 0 3 2 3 9 9 5 7 1 9
      Cellular, Molecular and Environmental Contribution in Cardiac Remodeling consolidates the most recent research advances on cellular, molecular, biochemical, and heterogeneous factors contributing to the physiological and pathological cardiac remodeling, elucidating their mechanisms of action and the clinical outcomes of cardiac remodeling. The book extensively covers the factors determining cardiac remodeling, including cardiomyocyte regeneration, cardiac stem cells and their therapeutic potential, cardiac resident pericytes, the role of natural bioactive compounds in cardiac remodeling, chronic cardiac adaptations to exercise, and more.It provides basic science researchers and clinical investigators in cardiology with a current and comprehensive resource on molecular mechanisms and contributing factors to cardiac remodeling, along with its effects and impacts on heart health. New research areas for the future, aimed at preventing, limiting, and reversing bad remodeling, are also discussed.

    • Translational Orthopedics

      • 1st Edition
      • April 15, 2024
      • Jeffrey A. Bakal + 4 more
      • English
      • Paperback
        9 7 8 0 3 2 3 8 5 6 6 3 8
      • eBook
        9 7 8 0 3 2 3 8 8 5 6 2 1
      Translational Orthopedics: Designing and Conducting Translational Research covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. Readers will come to fully understand important concepts, including case-control study, prospective cohort study, randomized trial, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in translational orthopedics, and know what is needed in collaboration. Further, this title is an indispensable tool in grant writing and funding efforts.The practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation. The book provides valuable discussions of the critical appraisal of published studies in translational orthopedics, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every Medical Researcher or Orthopedist who has ever had a good clinical idea but not the knowledge of how to test it.

    • Antioxidant Methods

      • 1st Edition
      • April 14, 2024
      • Francisco Avelino
      • English
      • Hardback
        9 7 8 0 4 4 3 2 1 5 9 1 9
      • eBook
        9 7 8 0 4 4 3 2 1 5 9 0 2
      Antioxidant Methods: A Guideline for Understanding and Determining AntioxidantCapacity summarizes the importance of antioxidants as a class of compounds withinnumerous areas of science and technology. The chapters elucidate diverse methodologiesfor assessing the antioxidant capacity of an antioxidant, while also exploring the correlationbetween its structural attributes and overall performance. Chapters include descriptions ofprotocols used to measure antioxidant capacity by different methods, highlighting experimentalsteps, bottlenecks, expected outcomes, advantages, limitations, and more.This is the perfect reference for biomedical science researchers looking for the right methodfor determining antioxidant capacity through the structure and functionalities of the compound,as well as the mechanisms involved in the antioxidant action.

    • Sinusoidal Cells in Liver Diseases

      • 1st Edition
      • April 9, 2024
      • Jordi Gracia-Sancho
      • English
      • Paperback
        9 7 8 0 3 2 3 9 5 2 6 2 0
      • eBook
        9 7 8 0 3 2 3 9 5 2 6 3 7
      Sinusoidal Cells in Liver Diseases: Role in their Pathophysiology, Diagnosis, and Treatment provides a state-of-the-art review on recent advances surrounding the role of liver sinusoidal cells (LSECs, HSCs, macrophages, and other non-parenchymal cells) in acute and chronic liver diseases. Coverage emphasizes disease pathophysiology, novel mechanisms, unmet clinical questions, development of biomarkers, and treatment opportunities. By focusing on the role of sinusoidal cells in human liver diseases, this reference provides a comprehensive overview of the role of sinusoidal cells in acute and chronic liver diseases, in its pathophysiology and mechanisms, and in the development of novel biomarkers and new therapeutics.Cells of the liver vasculature play an essential role in the pathophysiology of acute and chronic liver diseases and are considered key therapeutic targets to treat most of human hepatopathies. Coverage in this reference includes the phenotypic changes occurring in liver vascular cells and how cells contribute to the development of microcirculatory dysfunction, fibrosis, inflammation, and liver failure.

    • Mass-Action Law Dynamics Theory and Algorithm for Translational and Precision Medicine Informatics

      • 1st Edition
      • April 9, 2024
      • Ting-Chao Chou
      • English
      • Paperback
        9 7 8 0 4 4 3 2 8 8 7 4 6
      • eBook
        9 7 8 0 4 4 3 2 8 8 7 5 3
      “Mass-Action Law Dynamics Theory and Algorithm for Translational and Precision Medicine Informatics” provides a comprehensive overview and update of the mass-action law-based unified dose-effect biodynamics, pharmacodynamics, bioinformatics, and the combination index theorem for synergy definition (MAL-BD/PD/BI/CI). Contents advocate the fundamental MAL-PD/BI/CI/BI principle for biomedical R&D, clinical trials protocol design computerized data analysis, illustrates the MAL-dynamics theory with sample analysis, and includes data entry and automated computer report print-outs. In 11 sections “Mass-Action Law Dynamics Theory and Algorithm for Translational and Precision Medicine Informatics” leads the reader from an introduction and overview, to trial protocols and MAL-PD/CI approach for biomedical R&D in vitro and in animals. It describes the current Landscape of International FDA Drug Evaluation, Clinical Pharmacology, and Clinical Trials Guidance. This is a valuable resource for biomedical researchers, healthcare professionals, and students seeking to harness the power of data informatics in precision medicine.

    • Pathophysiology, Risk Factors, and Management of Chronic Heart Failure

      • 1st Edition
      • April 4, 2024
      • Ram B. Singh + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 9 7 2 9
      • eBook
        9 7 8 0 1 2 8 2 3 1 1 1 1
      Chronic Heart Failure: Pathophysiology, Risk Factors, and Mechanisms aims to provide an inclusive overview on Chronic Heart Failure (CHF).This book is focused on the epidemiology, classification, molecular mechanisms, pathophysiology, causes, identification and interactions of heart failure. It will explain the uncertainties and issues in Heart Failure by helping readers understand the physiopathology of CHF in the light of behavioural risk factors. 2D and 3D speckle tracking echocardiography have been used to quantify regional alterations of longitudinal strain and area strain, through their polar projection, which allows a further evaluation of both the site and extent of myocardial damage. The analysis of strain can identify subclinical cardiac failure (myocyte remodelling) which is a major issue in CHF. Myocardial Strain, measure by speckle tracking echocardiography, is frequently attenuated in these conditions and can be utilized for the evaluation of disease progression and the effect of therapeutic interventions as well as prevention because it could be a manifestation of behavioural risk factors.This title will function as an essential reference to both researchers and practicing clinicians, proposing novel methods of research by using behavioural and environmental risk factors as intervention agents, as well as discussing deficiency in the present approaches in management of HF and proposing new methods of early diagnosis and therapies for the clinical management of CHF.

    • COVID-19’s Consequences on the Cardiovascular System

      • 1st Edition
      • April 4, 2024
      • Fabian Sanchis-Gomar + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 9 0 9 1 9
      • eBook
        9 7 8 0 4 4 3 1 9 0 9 2 6
      Scientific evidence demonstrates that while COVID-19 primarily affects the lungs, it also affects multiple organs, particularly the cardiovascular system; its most common complications are arrhythmia, cardiac injury, fulminant myocarditis, heart failure, and pulmonary embolism. COVID-19’s Consequences on the Cardiovascular System: Immediate, Intermediate, and Long-Term Complications covers all aspects related to the interplay between SARS-COV-2 infection and the cardiovascular system, from bench to bedside and from acute infection to long-term complications.Writte... by a team of experts, this book is a one-stop-shop reference for healthcare professionals and researchers who require a comprehensive view of the deleterious effects of COVID-19 on the cardiovascular system. It discusses the relationship of cardiovascular risk factors with COVID-19 prognosis. It offers further insights into the biomarkers that currently make it possible to predict and monitor the evolution of the disease at the cardiovascular level.

    • Techniques for Biochemical Analysis

      • 1st Edition
      • April 4, 2024
      • Khursheed Hussain + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 5 9 1 4 5
      • eBook
        9 7 8 0 4 4 3 1 5 9 1 5 2
      Techniques for Biochemical Analysis provides researchers with a practical guide for investigating a variety of different biomolecules. It includes a range of tried and tested protocols, outlining the principles upon which each technique is founded, as well as providing instructions on equipment setup and use, buffer preparation, reagents required, safety considerations and analysis of findings. Beginning with an introduction to biochemistry and laboratory procedures, the book moves on to specific methods focused on investigation of carbohydrates, proteins, enzymes, plant hormones, minerals, amino acids, and more.The large range of protocols covered in this foundational, how-to reference are interdisciplinary and adaptable to a variety of areas, making this an ideal resource for researchers across various fields, including biochemistry, molecular biology, medical sciences, plant physiology, agriculture, and related subjects.

    • Fundamental Principles of Oxidative Stress in Metabolism and Reproduction

      • 1st Edition
      • April 1, 2024
      • Faiza Alam + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 8 8 0 7 7
      • eBook
        9 7 8 0 4 4 3 1 8 8 0 6 0
      Fundamental Principles of Oxidative Stress in Metabolism and Reproduction: Prevention and Management is a comprehensive resource for anyone needing awareness and recognition of oxidative stress as a basic component of disease to determine the precise treatment plan considering the cause of the disease. It describes the effects of oxidative stress in the human body, the detection of metabolic changes, psychological impact and effect on reproductive outcomes. In addition, it discusses alterations at the cellular level occurring due to oxidative stress along with the genetic aspects involved in its pathogenesis.

    • Exosomal RNA

      • 1st Edition
      • March 29, 2024
      • Debalina Bhattacharya + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 4 0 0 8 2
      • eBook
        9 7 8 0 4 4 3 1 4 0 0 7 5
      Exosomal RNA: Role in Human Diseases and Therapy provides an in-depth study of exosomes and their RNA in the context of a variety of diseases. The book explores the diagnostic and therapeutic potential of exosomal RNA as biomarkers across a range of different conditions, including cancer, type 2 diabetes, cardiovascular and renal disease, as well as bacterial infections and tissue repair. The link between exosomal RNA expression and neurodegenerative disease is also explored. The book goes on to share the significance of exosomal RNA in preserving cellular function, with special attention given to their role in the autophagy process.This book also gives an overview of the isolation, characterization, and potential applications of exosomal RNA, providing researchers with an understanding of how they can be manipulated and utilized for the treatment of various diseases and conditions. This is an ideal reference for researchers in the field of molecular biology, cell biology, and related fields, as well as those involved in the development of therapeutics and personalized medicine.

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