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COVID-19’s Consequences on the Cardiovascular System
Immediate, Intermediate, and Long-Term Complications
- 1st Edition - April 4, 2024
- Editors: Fabian Sanchis-Gomar, Amer Harky
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 9 0 9 1 - 9
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 9 0 9 2 - 6
Scientific evidence demonstrates that while COVID-19 primarily affects the lungs, it also affects multiple organs, particularly the cardiovascular system; its most common co… Read more
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Request a sales quoteScientific evidence demonstrates that while COVID-19 primarily affects the lungs, it also affects multiple organs, particularly the cardiovascular system; its most common complications are arrhythmia, cardiac injury, fulminant myocarditis, heart failure, and pulmonary embolism. COVID-19’s Consequences on the Cardiovascular System: Immediate, Intermediate, and Long-Term Complications covers all aspects related to the interplay between SARS-COV-2 infection and the cardiovascular system, from bench to bedside and from acute infection to long-term complications.
Written by a team of experts, this book is a one-stop-shop reference for healthcare professionals and researchers who require a comprehensive view of the deleterious effects of COVID-19 on the cardiovascular system. It discusses the relationship of cardiovascular risk factors with COVID-19 prognosis. It offers further insights into the biomarkers that currently make it possible to predict and monitor the evolution of the disease at the cardiovascular level.
- Covers all the current scientific pieces of evidence about the effects of COVID-19 on the heart and cardiovascular system from both a basic and a clinical point of view.
- Discusses immediate, intermediate, and long-term complications of COVID-19 on the cardiovascular system.
- Includes studies conducted worldwide by well-known experts in related fields.
Researchers, scientists, cardiologists and physicians interested in the impact of COVID-19 on the cardiovascular system
- Cover image
- Title page
- Table of Contents
- Copyright
- List of contributors
- Foreword
- Introduction
- Introduction
- Chapter 1. The pathophysiology of COVID-19 and the cardiovascular system
- Abstract
- Introduction
- Direct myocardial and pericardial injury by SARS-CoV-2
- Cardiovascular implications of SARS-CoV-2 effect on the renin-angiotensin system
- The inflammatory response to SARS-CoV-2 infection
- Cardiovascular implications of the cytokine storm
- Effect of cytokine storm on systemic vasculature
- Hypercoagulable state
- Disseminated intravascular coagulation
- The effect of SARS-CoV-2 on the pulmonary vasculature
- Conclusion
- References
- Chapter 2. Cardiovascular comorbidities and COVID-19 outcomes
- Abstract
- Introduction
- Risk of severity outcomes and mortality in COVID-19: scientific evidence
- Possible mechanisms involved
- Concluding remarks
- References
- Chapter 3. Prognostic role of troponins and other cardiac-related biomarkers in COVID-19
- Abstract
- What are biomarkers?
- The importance of cardiac biomarkers
- Role of troponins in COVID-19
- Role of CK-Mb in COVID-19
- Summary
- References
- Chapter 4. Cardiovascular medications and its relations with COVID-19 survival
- Abstract
- Introduction
- Drug categories
- Beta-adrenoceptor blockers
- Aspirin
- Angiotensin-converting enzyme inhibitors/angiotensin receptor blockers
- Anticoagulants
- Calcium channel blockers
- Diuretics
- Antiarrhythmics
- Statins
- Conclusion
- References
- Chapter 5. Imaging in Covid-19
- Abstract
- Chest radiographs
- Computerized tomography of the chest
- Lung ultrasound
- Magnetic resonance imaging
- Imaging of cardiovascular complications of Covid-19
- Conclusions
- References
- Chapter 6. Long-term impact of COVID-19 on the cardiovascular system
- Abstract
- Introduction
- Definitions of long-COVID
- Epidemiology of long-COVID
- Prevalence and predictors of long-COVID: increased risk of cardiovascular disease after COVID-19 infection
- Potential long-term cardiovascular effects of COVID-19
- The effect of long-COVID on the cardiovascular system
- Additional risk factors for developing severe and long-COVID cardiovascular disease complications
- Symptoms and pathophysiological mechanisms in long-COVID
- Diagnosis, management, and treatment of cardiovascular effects and complications
- The RECOVER Initiative at Stanford Medicine: an NIH-funded long-COVID study
- Concluding remarks and future directions
- Acknowledgment
- Funding
- Declaration of interest
- References
- Chapter 7. Pericardial and myocardial manifestations of COVID-19
- Abstract
- Introduction
- Pathophysiology
- Myocarditis
- Pericarditis and myopericarditis
- COVID vaccine
- Conclusion
- References
- Chapter 8. The thromboembolic effect of COVID-19
- Abstract
- Introduction
- Epidemiology of venous thromboembolism in COVID-19
- Prognosis of venous thromboembolism in COVID-19
- In situ pulmonary thrombosis
- Conclusions
- References
- Chapter 9. COVID-19 and platelets: an enigmatic relationship
- Abstract
- Introduction
- Platelet count in COVID-19
- Platelet volume in COVID-19
- Immature platelets in COVID-19
- Biological basis of platelet abnormalities in COVID-19
- Antiplatelet treatment in COVID-19
- Conclusions
- Acknowledgments
- Funding
- Declaration of interest
- References
- Chapter 10. Cardiology service and COVID-19: the international impact
- Abstract
- Introduction
- The impact in Africa
- The impact in Europe
- Outpatient
- Inpatient
- Conclusion
- COVID-19 and its impact on cardiology services in Asia
- COVID-19 pandemic impact on the US Cardiology Service
- HIPAA and temporary waiver of Medicare restrictions
- Inpatient cardiology services and reimbursement structure for ITH
- References
- Chapter 11. Cardiovascular surgery services during COVID-19 pandemic
- Abstract
- Introduction
- Impact of COVID-19 on cardiovascular surgery services
- Responses and adaptations of cardiovascular surgery services to COVID-19
- Innovation in cardiovascular surgery services during the pandemic
- Future perspectives
- Conclusion
- References
- Chapter 12. Cardiac arrhythmia and sudden death in relation to COVID-19
- Abstract
- Introduction
- Pathophysiology of arrhythmias in previous coronavirus outbreaks
- Pathophysiology of arrhythmias in cases of influenza virus
- Pathophysiology of arrhythmias in SARS-CoV-2
- Electrolyte abnormalities and cardiac arrhythmias
- Inflammatory markers and their mediation of cardiac arrhythmias
- Hypoxia-induced cardiac arrhythmias
- Drug effect for COVID-19 management and interactions with other medications
- Structural heart disease
- Pulmonary embolism and its associated arrhythmias
- Adrenergic stress leading to arrhythmias
- Sudden death in COVID-19
- Mechanism of sudden cardiac death in COVID-19
- Management
- References
- Chapter 13. Heart failure and acute coronary syndrome with COVID-19
- Abstract
- Heart failure and COVID-19
- Acute coronary syndrome (ACS) and COVID-19
- References
- Chapter 14. Vascular and autoimmune diseases interaction with COVID-19
- Abstract
- Introduction
- An overview of COVID-19 infection on autoimmune conditions, proposed mechanisms, and implications in clinical practice
- COVID-19 vaccination and its possible implications on the development of autoimmune conditions
- Conclusion and reflections
- References
- Chapter 15. Safety of anti-COVID treatments on the cardiovascular system
- Abstract
- Introduction
- Antivirals
- Monoclonal antibodies
- Corticosteroids
- Immunomodulators
- References
- Chapter 16. Return to the competition for athletes after SARS-CoV-2 infection resolution from a cardiac perspective
- Abstract
- Return to play protocol
- ECG, exercise test, 24-hour ambulatory ECG monitoring, and cardiopulmonary exercise testing
- Echocardiogram
- Cardiac MRI
- Blood tests
- Respiratory assessment
- Post-COVID-19 training
- Long COVID
- References
- Chapter 17. Multifactorial prevention and preparation for the next pandemic
- Abstract
- Strengthening early detection and response to pandemics: strategies for global preparedness
- Promoting effective sanitation and hygiene for disease prevention and control
- Vaccination
- Antimicrobial stewardship
- Environment conservation
- Research and development: advancing pandemic preparedness
- References
- Chapter 18. Conclusions and future perspectives
- Abstract
- Index
- No. of pages: 288
- Language: English
- Edition: 1
- Published: April 4, 2024
- Imprint: Academic Press
- Paperback ISBN: 9780443190919
- eBook ISBN: 9780443190926
FS
Fabian Sanchis-Gomar
Dr Sanchis-Gomar graduated in Medicine from the University of Valencia (Spain), where he also received his PhD degree. His main area of interest is exercise-induced damage such as myocardial fibrosis, inflammation, pathological remodeling, and arrhythmias as well as its implications in sudden cardiac death. During the COVID pandemic, Dr Sanchis-Gomar became an expert in COVID-19, with in-depth knowledge of the subject and actively involved in research. He is an authority in the field, being considered by expertscape among the top 20 experts in COVID-19 worldwide, and has published numerous articles in prestigious Journals, such as the New England Journal of Medicine, Lancet Diabetes and Endocrinology, JAMA Cardiology and others.
Affiliations and expertise
Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USAAH
Amer Harky
Dr Harky is a cardiothoracic surgery specialty trainee at the Liverpool Heart and Chest Hospital (United Kingdom). He has a special interest in COVID-19 related pathophysiology including cardiovascular manifestations as well as management strategies. He has published more than 70 articles in this regard and is considered by expertscape among the top 10 experts in this field within the academic world in England.
Affiliations and expertise
Department of Cardiothoracic Surgery, Liverpool Heart and Chest Hospital, Liverpool, United KingdomRead COVID-19’s Consequences on the Cardiovascular System on ScienceDirect