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Elsevier

Books in Molecular biology cellular biology and genetics

This collection offers insights into gene expression, cell signalling, and genetic regulation. Supporting researchers, clinicians, and students, it features advanced techniques, genetic engineering, and disease mechanisms, fostering innovations in personalized medicine, regenerative therapies, and molecular diagnostics.

  • Recent Progress in Hormone Research

    Proceedings of the 1984 Laurentian Hormone Conference
    • 1st Edition
    • Roy O. Greep
    • English
    Recent Progress in Hormone Research, Volume 41 covers the proceedings of a Laurentian Hormone Conference held in late August 1984 at the Homestead in Hot Springs, Virginia. The book presents papers on the hormone-receptor interactions; the biosynthesis, secretion, metabolism, and mechanism of action of the steroid hormones; and the mechanisms of action of thyroid-stimulating hormone (TSH) and TRH. The text also includes papers on the molecular characterization of a brain specific mRNA; and the factors affecting changes in frequency and amplitude of GnRH pulses and the resulting functional consequences in various mammals including humans with disorders of fertility. Papers on the biological heritage of mammalian endocrinology, such as the actions of urotensin I in mammals and fishes; and the clinical implications of the glycosylation and posttranslational processing of the TSH are also encompassed. Endocrinologists, neuroscientists, biochemists, biophysicists, and scientists involved in hormone research will find the book invaluable.

  • Current Problems in the Epidemiology of Cancer and Lymphomas

    Recent Results in Cancer Research
    • 1st Edition
    • E. Grundmann + 1 more
    • English
    Recent Results in Cancer Research: Current Problems in the Epidemiology of Cancer and Lymphomas is a collection of papers that tackles the various areas of concerns in cancer research. The text covers the general problems, such as the histopathological definition and classification of tumors. The book also deals with the various types of cancer, such as breast, liver, and prostrate cancers. The selection will be of great use for medical researchers and practitioners, particularly those who are involved in treating and studying cancers.

  • Hypothalamic Control of Lactation

    Monographs on Endocrinology
    • 1st Edition
    • F. G. Sulman
    • F. Gross + 2 more
    • English
    Monographs on Endocrinology, Volume 3: Hypothalamic Control of Lactation provides information pertinent to the fundamental aspects of lactation, which is dependent upon the temporal cortex of the brain. This book discusses the manifold problems of hypothalamic lactation. Organized into four parts encompassing 30 chapters, this volume begins with an overview of the mechanisms of lactation and explores the hormone requirements for mammary development in various species. This text then examines the theory of the anterior pituitary gland being controlled by neurohumors carried through the hypophysial portal circulation. Other chapters consider the physiology of pituitary prolactin, which is distinguished from other pituitary tropins by its inhibitory regulation originating in the central nervous system. This book discusses as well the mechanism of the lactogenic effect of hypothalamic tranquilizers. The final chapter deals with the structure of the hypothalamic factors responsible for lactation. This monograph is a valuable resource for endocrinologists, scientists, students, and researchers.

  • Urine Analysis

    • 1st Edition
    • Byomkes Das Gupta
    • English
    Urine Analysis presents the theory and methods of urine analysis, which serves as a guide for physicians and medical laboratory technicians. Topics discussed in the book include the physical examination of urine; its chemical examination; microscopical examination; and Ehrliches Diazo reaction. Physicians and medical laboratory technicians will find the book a very valuable reference material.

  • Autoradiography and Immunocytochemistry

    Practical Methods in Electron Microscopy
    • 1st Edition
    • M.A. Williams
    • Audrey. M. Glauert
    • English
    Autoradiography and Immunocytochemistry sets out in detail the preparation of autoradiographs and methods of preparing and use of immunological staining reagents. This book begins with an introduction to the demand for autoradiography and immunocytochemistry and their most advantageous use, followed by a discussion on the immunocytochemistry at the electron microscopical (EM) level in relation to the preparation of labeled antibodies. Other topics include the general remarks on “staining” with antibodies; applying Fer-Ab conjugates to ultrathin sections; and controls in immunoferritin staining. The multistep antibody staining methods with unmodified proteins; control observations in staining experiments using lectins; and pattern analysis in EM immunocytochemistry are also covered. This text concludes with a description of the preparation of electron microscope autoradiographs, including the radioisotopes in EM autoradiography, preparation of radioactively-labele... tissues and cells, and methods of applying nuclear emulsions. This publication serves as a detailed laboratory guide for researchers and workers to successfully conduct electron microscope techniques.

  • Recent Progress in Hormone Research - Volume 50

    Proceedings of the 1993 Laurentian Hormone Conference
    • 1st Edition
    • C. Wayne Bardin
    • English
    Recent Progress in Hormone Research, Volume 50: Proceedings of the 1993 Laurentian Hormone Conference focuses on the advancements of processes, methodologies, techniques, and approaches involved in hormone research. The selection first offers information on the molecular design of the NMDA receptor channel; synthesis and signaling of growth hormone-releasing hormone; and signaling mechanisms during the response of pituitary gonadotropes to GnRH. The discussions focus on calcium economy of gonadotropes, role of oscillations, structure and expression of the GHRH gene, transgenic animal models for GHRH action, and functional determinants in NMDA receptors. The text then elaborates on signaling mechanisms during the response of pituitary gonadotropes to GnRH; molecular genetic analysis of cAMP and glucocorticoid signaling in development; and activins and the receptor serine kinase superfamily. The publication takes a look at MAP kinase cascade, expression and signal transduction pathways of gonadotropin-releasi... hormone receptors, ovarian cell differentiation, and the role of oxytocin and its receptor in parturition. The book also examines the role of prolactin in developmental differentiation of hypophysiotropic tuberoinfundibular dopaminergic neurons and calcitonin gene expression in rat uterus during pregnancy. The selection is a valuable source of data for researchers interested in hormone research.

  • Biochemical and Molecular Aspects of Selected Cancers

    Volume 2
    • 2nd Edition
    • Thomas G. Pretlow II
    • English
    This two-volume work not only includes much of the newer molecular biology research but also important earlier research in this area essential for the comprehensive understanding of the biochemistry of neoplastic diseases. As such it will provide an invaluable source of information for the young investigator. Human cancers, not experimental models of cancer, are emphasized.

  • Hormones and Embryonic Development

    Advances in the Biosciences
    • 1st Edition
    • G. Raspé
    • English
    Advances in the Biosciences 13: Hormones and Embryonic Development investigates various aspects of hormones and embryonic development, including their physiological and pharmacological effects. More specifically, this volume considers which maternal hormones are essential for normal mammalian embryonic development, as well as the time course of the occurrence of endocrine systems during mammalian fetal development. In addition, it examines the role of maternal or fetal hormones in the induction and differentiation processes during embryonic or fetal development. Comprised of 13 chapters, this book begins with an analysis of the metabolic effects of insulin and glucagon in fetal and newborn rats, as well as their physiologic significance during the perinatal period in rat and other species. The next chapter deals with sexual differentiation in the rat fetus; how hormones regulate sexual development and disrupt sexual differentiation; the role of progesterone and estrone in pregnant rats fed a protein-free diet; and effects of brain implants of testosterone propionate in newborn hamsters on sexual differentiation. The link between diethylstilbestrol ingestion during pregnancy and development of clear-cell adenocarcinoma in the vagina and cervix of the female offspring is also examined. This monograph will be of interest to biologists, bioscientists, physiologists, and pharmacologists.

  • Mammalian Cytogenetics and Related Problems in Radiobiology

    Proceedings of a Symposium Held at São Paulo and Rio De Janeiro, Brazil, October 1962
    • 1st Edition
    • C. Pavan + 2 more
    • English
    Mammalian Cytogenetics and Related Problems in Radiobiology covers the proceedings of a symposium held in Sao Paulo and Rio de Janeiro, Brazil in October 1962. The book focuses on the processes, methodologies, and approaches involved in mammalian cytogenetics and radiobiology. The selection first offers information on the nutrition and metabolism of cultured mammalian cells, blood technique and human chromosomes, and DNA replication in human chromosomes. Discussions focus on replication of heterochromatin in the human male; difficulties involved in the study of DNA synthesis in human chromosomes; and perspectives for future research. The text then ponders on the progress in the utilization of cell culture techniques for studies in mammalian and human somatic cell genetics and modification of radiation effects in the Ehrlich ascites tumor by oxygen or sodium azide. The manuscript examines experimental studies on mammalian chromosome aberrations, chromosome breakage in vitro, and survival of human cells in tissue culture after irradiation with densely and sparsely ionizing radiation. The text then elaborates on the observations on the morphology and behavior of normal human chromosomes, human pachytene chromosomes, and abnormalities of autosomes. The selection is a vital reference for readers interested in mammalian cytogenetics and radiobiology.

  • Molecular Cell Pathology

    • 1st Edition
    • G. W. Richter + 1 more
    • English
    International Review of Experimental Pathology, Volume 32: Molecular Cell Pathology discusses the applications and practical value of in situ hybridization; the interactions between endothelial cells and the cells of the immune system; and the molecular biology of cytokine effects on vascular endothelial cells. The text also describes the interphase nucleolar organizer regions in cancer cells; the disease associations, molecular biology, and pathophysiology of antineutrophil cytoplasmic autoantibodies; and the mechanisms and roles of apoptosis in pathology. The molecular events in measles virus infection of the central nervous system are also considered. Pathologists, microbiologists, and immunologists will find the book useful.

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