Books in Molecular biology cellular biology and genetics

The Origin and Domestication of Cultivated Plants

1st Edition
December 2, 2012
C. Barigozzi
English
eBook
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This book consists of the proceedings of a symposium organized by the Accademia Nazionale dei Lincei, Rome. The proceedings are unusual in that it is a rare event to see archaeologists and geneticists coming together to discuss the connection between historical facts and biological phenomena. The aim of the symposium was to discuss the origin of some important cultivated plants (wheat, maize, barley, oat, legumes and fruit trees) not only in relation to genetical mechanisms but also as a complex of historical facts recognizable through archaeological research.This international Meeting based on interdisciplinary concepts, met with a prompt and positive reaction from all those specialists invited to attend. The book itself is an unparalleled contribution to the interdisciplinary knowledge on the origin of crop plants and agriculture.

Molecular Action of Toxins and Viruses

1st Edition
Volume 2
December 2, 2012
P. Cohen + 1 more
English
eBook
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Molecular Action of Toxins and Viruses investigates the molecular action of bacterial toxins and viruses and its striking similarity to the mechanisms by which many neural and hormonal stimuli control normal cell functions. Topics covered include the biological activity of diphteria toxin; the role of cholera toxin in the regulation of hormone-sensitive adenylate cyclase; toxic lectins and related proteins; and bacterial cytolysins (membrane-damaging toxins). Comprised of nine chapters, this volume begins with a discussion on the biosynthesis and biological activity of diphtheria toxin, toxin-resistant mutant cells, and the entry of toxin into cells and fragment A in the cytoplasm of living cells. The reader is then systematically introduced to the use of cholera toxin as a probe to study the regulation and interaction of adenylate cyclase components; the toxic action of lectins and related proteins such as abrin, ricin, and modeccin; and the ability of bacterial cytolysins to damage cell membranes. The remaining chapters focus on the mechanism of action of colicin E2, colicin E3, and cloacin DF13; similarities in the action of different bacterial toxins; the role of cell membranes in infection with bacterial viruses and colicins; and the life cycle and infection mechanisms of bacteriophage T4. The book concludes with an analysis of the involvement of protein kinases in viral transformation. This monograph will be of interest to students, practitioners, and researchers in fields ranging from molecular biology and biochemistry to cell biology, bacteriology, and physiology.

Handbook of Mutagenicity Test Procedures

2nd Edition
December 2, 2012
B.J. Kilbey + 3 more
English
eBook
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The compilation of this book was prompted by the necessity of a bench volume which could provide the necessary background information on materials, experimental design, pitfalls and dificulties, in order to perform a particular test in an acceptable way with a minimal need for additional expert help. This Second Edition updates this information, providing: - a comprehensive bench guide - methods known to be reliable - a broad spectrum of approaches - tips to avoid pitfalls when using unfamiliar techniques - data from population records - safety aspects of mutagens and carcinogens - basic statistical concepts for experiment design This `on the bench' methodological text provides the necessary information for most of the common assays for genetic damage in use. The book includes methods which have been sufficiently used and tested to make their use reliable, but also presents methods which are not widely used at present, but which might prove most useful in screening for mutagenic effects.

Selected Topics in the History of Biochemistry

1st Edition
Volume 36
December 2, 2012
G. Semenza
English
eBook
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One of the most exciting developments in biological sciences has been their merging with chemistry and physics resulting in the new disciplines of biochemistry, biophysics and molecular biology. As the developments of these new disciplines has been so rapid many of the key discoveries have occurred within the life-time of a number of prominent scientists in the field. The chapters in this and in future volumes are meant to complement with personal recollections by these scientists, the History of Biochemistry in this series (vols. 30-33 by M. Florkin and Vol. 34 by P. Laszlo). These bibliographic and autobiographic chapters convey to the reader lively, albeit at times subjective, views on both the scientific and social environments of the authors. The editor cosidered it presumptuous to give the authors narrow guidelines or to suggest changes in the chapters he received. The contributions assembled in this volume will convey the flavour of each author's particular personality.

RNA: Catalysis, Splicing, Evolution

1st Edition
December 2, 2012
M. Belfort + 1 more
English
eBook
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The conference on "RNA: Catalysis, Splicing, Evolution" brought together a unique assembly of scientific leaders in this currently very important field. Two participants of this Conference, Drs. T.R. Cech and S. Altman, were just awarded the 1989 Nobel prize in chemistry, which attests to the timeliness of this volume. The critical reviews authored by these two prominent scientists are included. For those scientists with roots in this field, who do not subscribe to GENE, this is an excellent opportunity to obtain a masterly collection of papers. All the original papers and reviews have undergone the rigorous peer review of the journal "Gene".

The Hormonal Control of Gene Transcription

1st Edition
Volume 6
December 2, 2012
P. Cohen + 1 more
English
eBook
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Over the past few years there have been considerable advances in our understanding of cellular control mechanisms, and current research is now linking areas of biology that were previously thought of as being quite separate. Molecular Aspects of Cellular Regulation is a series of occasional books on multidisciplinary topics which illustrate general principles of cellular regulation. Previous volumes described Recently Discovered Systems of Enzyme Regulation by Reversible Phosphorylation (Volumes 1 and 3), The Molecular Actions of Toxins and Viruses (Volume 2), Molecular Mechanisms of Transmembrane Signalling (Volume 4) and Calmodulin (Volume 5). This sixth volume, The Hormonal Control of Gene Transcription, has now been published to highlight recent important advances in our understanding of this topic which is linking two of the most active areas of current biochemical and molecular biological research (hormone action and gene transcription) and leading to the emergence of unifying concepts.

Proteins: Form and Function

1st Edition
December 2, 2012
R.A. Bradshaw + 1 more
English
eBook
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Proteins are of fundamental importance in all aspects of cell structure and function. The study of proteins has always formed a central part of biochemistry, and recent expansion in the range and sophistication of available techniques has provided a wealth of new information. The current methods and approaches used to gain a better understanding of the structure of proteins are described within this book, while other articles focus on the role of proteins within the cell.Most of the articles have appeared previously in the monthly review journal Trends in Biochemical Sciences (TIBS), with a few commissioned specifically for this collection, which should appeal to students, lecturers and researchers interested in the form and function of proteins.

Systems Biology of Bacteria

1st Edition
Volume 39
November 28, 2012
Anil Wipat + 1 more
English
Hardback
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eBook
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Focusing on the systems biology of bacteria and microorganisms, the 39th volume of Methods in Microbiology investigates the interface between molecular biology, bioinformatics, and modelling and predicting behavior. This cutting-edge research area is of extreme importance to the field and is developing quickly.

Laboratory Methods in Cell Biology

1st Edition
Volume 112
November 28, 2012
P. Michael Conn
English
Hardback
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eBook
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Cell biology spans among the widest diversity of methods in the biological sciences. From physical chemistry to microscopy, cells have given up with secrets only when the questions are asked in the right way! This new volume of Methods in Cell Biology covers laboratory methods in cell biology, and includes methods that are among the most important and elucidating in the discipline, such as transfection, cell enrichment and magnetic batch separation.

Eukaryotic RNases and their Partners in RNA Degradation and Biogenesis

1st Edition
Volume 32
November 27, 2012
Fuyuhiko Tamanoi + 2 more
English
Hardback
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eBook
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This special volume of The Enzymes is targeted towards researchers in biochemistry, molecular and cell biology, pharmacology, and cancer. This thematic volume discusses Eukaryotic RNases and their partners in RNA degradation and biogenesis.

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