Skip to main content
Elsevier

Academic Press

  • Recent Advances in iPSC Technology

    • 1st Edition
    • Alexander Birbrair
    • English
    The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology.Recent Advances in iPSC Technology, Volume 5 addresses the progress in induced pluripotent stem cells (iPSCs) technologies.Somatic cells can be reprogrammed into iPSCs by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. The volume teaches readers about current advances in the field. This book describes different technologies and strategies to use iPSCs for biological and clinical benefit. In recent years, remarkable progress has been made in the obtention of iPSCs and their differentiation into several cell types, tissues, and organs using state-of-the-art techniques. These advantages facilitated identification of key targets and definition of the molecular basis of several disorders. This volume will cover hot topics in the iPSC field, such as iPSCs for modeling the cardiovascular toxicities of anticancer therapies, iPSC differentiation through the lens of the noncoding genome, modeling of blood–brain barrier with iPSCs, mathematical modeling of iPSCs, iPSCs to study human brain evolution, selfrenewal in iPSCs, differences and similarities between iPSCs and embryonic stem cells, and more.The volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and organ transplantation and is contributed by world-renowned authors in the field.

  • Handbook of Decision Support Systems for Neurological Disorders

    • 1st Edition
    • D. Jude Hemanth
    • English
    Handbook of Decision Support Systems for Neurological Disorders provides readers with complete coverage of advanced computer-aided diagnosis systems for neurological disorders. While computer-aided decision support systems for different medical imaging modalities are available, this is the first book to solely concentrate on decision support systems for neurological disorders. Due to the increase in the prevalence of diseases such as Alzheimer, Parkinson’s and Dementia, this book will have significant importance in the medical field. Topics discussed include recent computational approaches, different types of neurological disorders, deep convolution neural networks, generative adversarial networks, auto encoders, recurrent neural networks, and modified/hybrid artificial neural networks.

  • Basic Principles of Drug Discovery and Development

    • 2nd Edition
    • Benjamin E. Blass
    • English
    Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields. Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics. Given the wide range of disciplines and techniques that are required for cutting edge drug discovery and development, a scientist must master their own fields as well as have a fundamental understanding of their collaborator’s fields. This book bridges the knowledge gaps that invariably lead to communication issues in a new scientist’s early career, providing a fundamental understanding of the various techniques and disciplines required for the multifaceted endeavor of drug research and development. It provides students, new industrial scientists, and academics with a basic understanding of the drug discovery and development process. The fully updated text provides an excellent overview of the process and includes chapters on important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles of in vivo pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process.

  • The Natural Language for Artificial Intelligence

    • 1st Edition
    • Dioneia Motta Monte-Serrat + 1 more
    • English
    The Natural Language for Artificial Intelligence presents the biological and logical structure typical of human language in its dynamic mediating process between reality and the human mind. The book explains linguistic functioning in the dynamic process of human cognition when forming meaning. After that, an approach to artificial intelligence (AI) is outlined, which works with a more restricted concept of natural language that leads to flaws and ambiguities. Subsequently, the characteristics of natural language and patterns of how it behaves in different branches of science are revealed to indicate ways to improve the development of AI in specific fields of science. A brief description of the universal structure of language is also presented as an algorithmic model to be followed in the development of AI. Since AI aims to imitate the process of the human mind, the book shows how the cross-fertilization between natural language and AI should be done using the logical-axiomatic structure of natural language adjusted to the logical-mathematical processes of the machine.

  • Private Equity and Venture Capital in Europe

    Markets, Techniques, and Deals
    • 3rd Edition
    • Stefano Caselli + 1 more
    • English
    Private Equity and Venture Capital in Europe: Markets, Techniques, and Deals, Third Edition introduces private equity, investments and venture capital markets while also presenting new information surrounding the core of private equity, including secondary markets, private debt, PPP within private equity, crowdfunding, venture philanthropy, impact investing, and more. Every chapter has been updated with new data, cases, examples, sections and chapters that illuminate elements unique to the European model. With the help of new pedagogical materials, this updated edition provides marketable insights about valuation and deal-making not available elsewhere. As the private equity world continues to undergo many challenges and opportunities, this book presents both fundamentals and advanced topics that will help readers stay informed on market evolution.

  • Reprogramming the Genome: Applications of CRISPR-Cas in non-mammalian systems part A

    • 1st Edition
    • Volume 179
    • English
    Reprogramming the Genome: Applications of CRISPR-Cas in Non-mammalian Systems, Part A presents a collation of chapters written by global, eminent scientists. CRISPR-Cas9 system is an RNA-mediated immune system of bacteria and archaea that protects from bacteriophage infections. It is one of the revolutionized technologies to uplift biology to the next stages. Chapters in this release include An Introduction and applications of CRISPR-Cas Systems, History, evolution and classification of CRISPR-Cas associated systems, CRISPR based bacterial genome editing and removal of pathogens, CRISPR based genome editing and removal of human viruses, CRISPR based development of RNA editing and diagnostic platform, and much more. Additional sections cover Genome engineering in insects for control of vector borne diseases, Development of insect cell line using CRISPR technology, CRISPRing protozoan parasites to better understand the biology of diseases, CRISPR based genome editing of Caenorhabditis elegans, and a variety of other important topics.

  • Hardware Accelerator Systems for Artificial Intelligence and Machine Learning

    • 1st Edition
    • Volume 122
    • English
    Hardware Accelerator Systems for Artificial Intelligence and Machine Learning, Volume 122 delves into artificial Intelligence and the growth it has seen with the advent of Deep Neural Networks (DNNs) and Machine Learning. Updates in this release include chapters on Hardware accelerator systems for artificial intelligence and machine learning, Introduction to Hardware Accelerator Systems for Artificial Intelligence and Machine Learning, Deep Learning with GPUs, Edge Computing Optimization of Deep Learning Models for Specialized Tensor Processing Architectures, Architecture of NPU for DNN, Hardware Architecture for Convolutional Neural Network for Image Processing, FPGA based Neural Network Accelerators, and much more.

  • What does Medial Frontal Cortex Signal During Behavior? Insights from Behavioral Neurophysiology

    • 1st Edition
    • Volume 158
    • English
    What does Medial Frontal Cortex Signal During Behavior? Insights from Behavioral Neurophysiology, Volume 158 addresses and highlights a question that has remained central to cognitive and systems neuroscience since its inception, namely, what does the medial frontal cortex do? With insights from 17 of the fields leading teams of scientists, this volume attempts to address this question covering several topics with chapters including What do single unit responses in dorsal anterior cingulate cortex mean?, Social Processing by the Primate Medial Frontal Cortex, Medial frontal cortex and the temporal control of action, The midcingulate cortex and temporal integration, and more. Additional chapters cover The anterior cingulate cortex and event-based modulation of autonomic states, Integration of value and action in medial prefrontal neural systems, Secondary motor cortex: broadcasting and biasing animal’s decisions through long-range circuits, The prefrontal cortex in social cognition, Representing task strategies in the medial prefrontal cortex, Prefrontal contributions to action control in rodents, From affective to cognitive processings: functional organization of the medial frontal cortex, and much more.

  • Thinking Machines

    Machine Learning and Its Hardware Implementation
    • 1st Edition
    • Shigeyuki Takano
    • English
    Thinking Machines: Machine Learning and Its Hardware Implementation covers the theory and application of machine learning, neuromorphic computing and neural networks. This is the first book that focuses on machine learning accelerators and hardware development for machine learning. It presents not only a summary of the latest trends and examples of machine learning hardware and basic knowledge of machine learning in general, but also the main issues involved in its implementation. Readers will learn what is required for the design of machine learning hardware for neuromorphic computing and/or neural networks.This is a recommended book for those who have basic knowledge of machine learning or those who want to learn more about the current trends of machine learning.

  • Web Semantics

    Cutting Edge and Future Directions in Healthcare
    • 1st Edition
    • Sarika Jain + 2 more
    • English
    Web Semantics strengthen the description of web resources to exploit them better and make them more meaningful for both humans and machines, thereby contributing to the development of a knowledgeintensive data web. The world is experiencing the movement of concept from data to knowledge and the movement of web from document model to data model. The underlying idea is making the data machine understandable and processable. In the light of these trends, conciliation of Semantic and the Web is of paramount importance for further progress in the area. Web Semantics: Cutting Edge and Future Directions in Healthcare describes the three major components of the study of Semantic Web, namely Representation, Reasoning, and Security with a special focus on the healthcare domain. This book summarizes the trends and current research advances in web semantics, emphasizing the existing tools and techniques, methodologies, and research solutions. It provides easily comprehensible information on Web Semantics including semantics for data and semantics for services.

Browse by Publisher