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Elsevier

Blood Gases and Critical Care Testing

Physiology, Clinical Interpretations, and Laboratory Applications

  • 3rd Edition - October 8, 2021
  • Latest edition
  • Authors: John G. Toffaletti, Craig R. Rackley
  • Language: English

Blood gas tests are a group of tests that are widely used and essential for the evaluation and management of a patient’s ventilation, oxygenation, and acid-base balance, often in… Read more

Description

Blood gas tests are a group of tests that are widely used and essential for the evaluation and management of a patient’s ventilation, oxygenation, and acid-base balance, often in emergent situations, and along with blood gases are other critical care analytes measured on blood: calcium, magnesium, phosphate, and lactate. Blood Gases and Critical Care Testing: Clinical Interpretations and Laboratory Applications, Third Edition, serves as your single most important reference for understanding blood gases and critical care testing and interpretation.

The third edition of this classic book is a complete revision and provides the fundamentals of blood gas (pH, pCO2, pO2) and other critical care tests (calcium, magnesium, phosphate, and lactate), including the history, the definitions, the physiology, and practical information on sample handling, quality control and reference intervals. Case examples with clear clinical interpretations of critical care tests have been included to all chapters.

This book will serve as a valuable and convenient resource for clinical laboratory scientists in understanding the physiology and clinical use of these critical care tests and for providing practical guidelines for successful routine testing and quality monitoring of these tests.

Key features

  • Provides a step-by-step approach for organizing and evaluating clinical blood gas and critical care test results
  • Describes several calculated parameters that are used by clinicians for evaluating a patient’s pulmonary function and oxygenation status and discusses clinical examples of their use
  • This new edition includes more detailed information about reference intervals, not only for arterial blood, but for venous blood and umbilical cord blood, and for pH in body fluids
  • Covers practical information on sample handling and quality control issues for blood gas testing

Readership

Pathologists, clinical chemists, clinical laboratory scientists, graduate students in laboratory studies, critical care physicians. Respiratory therapists, physicians in pulmonary medicine

Table of contents

1. Introduction to Blood Gases and Blood Gas Physiology

2. Physiologic Mechanisms and Diagnostic Approach to Acid-Base Disorders

3. Interpreting Blood Gas Results on Venous, Capillary, and Umbilical Cord Blood

4. Disorders of Oxygenation: Hypoxemia and Tissue Hypoxia

5. Calcium Physiology and Diagnostic Evaluation

6. Magnesium Physiology and Diagnostic Evaluation

7. Phosphate Physiology and Diagnostic Evaluation

8. Osmolality, Sodium, Potassium, Chloride, and Bicarbonate Osmolality and Volume Regulation

9. Lactate Physiology and Diagnostic Evaluation

10. Collection and Handling of Samples: Effects on Blood Gases and Electrolytes: Na, K, Ionized Ca, Mg, Lactate, Phosphate Analysis

11. Quality Control in Blood Gas and Critical Care Testing

12. Models for Point of Care Testing for Critical Care Analytes

Review quotes

"This is a fantastic book on blood gases and critical care testing (electrolytes - sodium, potassium, chloride, bicarbonate, magnesium, phosphate, lactate). It is definitely a step up from the previous edition. If you've ever had questions about the technical or clinical aspects of this testing, this is the book for you"—© Doody’s Review Service, 2021, Valerie L Ng, PhD MD, reviewer, expert opinion

Product details

  • Edition: 3
  • Latest edition
  • Published: October 14, 2021
  • Language: English

About the authors

JT

John G. Toffaletti

Dr. John Toffaletti is a Professor of Pathology at Duke University Medical Center, where since 1979 he has worked in the Clinical Laboratories and now directs the Blood Gas Laboratory, the Clinical Pediatric Laboratory, and several outpatient clinic laboratories. He also serves as Chief of Clinical Chemistry at the Durham VA Medical Center. He earned a BS in Chemistry from the University of Florida–Gainesville, a PhD in Biochemistry from UNC Chapel Hill, and completed a Postdoctoral Fellowship in Clinical Chemistry at Hartford Hospital. He has authored and presented extensively on blood gas interpretation, cooximetry, ionized calcium, magnesium, lactate in sepsis, kidney function tests (creatinine, cystatin C, GFR), and viscoelastic testing (ROTEM and TEG). His research interests include sample collection, pre-analytical errors, analytical methods, and the clinical use of these tests.
Affiliations and expertise
Director, Clinical Pediatric Laboratory, Blood Gas Laboratory, Duke University Medical Center

CR

Craig R. Rackley

Dr. Craig R. Rackley is an Associate Professor of Medicine in the Division of Pulmonary, Allergy, and Critical Care Medicine at Duke University Medical Center. He serves as Medical Director of Respiratory Care and the Adult ECMO Program at Duke University Hospital. Dr. Rackley’s clinical and academic work focuses on acute respiratory failure, advanced life support, and the physiologic assessment of critically ill patients. He has published extensively on mechanical ventilation, oxygenation, ECMO, and critical care physiology and is a nationally recognized educator in respiratory physiology and critical care medicine.
Affiliations and expertise
Associate Professor, Duke University Medical Center, USA

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