Methodological Approaches for Sleep and Vigilance Research
- 1st Edition - October 9, 2021
- Imprint: Academic Press
- Editor: Eric Murillo-Rodriguez
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 8 5 2 3 5 - 7
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 0 3 3 4 - 9
Methodological Approaches for Sleep and Vigilance Research examines experimental procedures used to study the sleep-wake cycle, with topics covered by world leaders in the field.… Read more
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Request a sales quoteMethodological Approaches for Sleep and Vigilance Research examines experimental procedures used to study the sleep-wake cycle, with topics covered by world leaders in the field. The book focuses on techniques commonly used in the sleep field, including polysomnography, electrophysiology, single- and multi-unit spiking activity recording, brain stimulation, EEG power spectra, optogenetics, telemetry, and wearable and non-wearable tracking devices. Further chapters on imaging techniques, questionnaires for sleep assessment, genome-wide association studies, artificial intelligence and big data are also featured. This discussion of significant conceptual advances into experimental procedures is suitable for anyone interested in the neurobiology of sleep.
- Discusses current sleep research methodologies for experienced scientists
- Focuses on techniques that allow measurement or assessment for the sleep-wake cycle
- Outlines mainstream research techniques and experimental characteristics of their uses
- Includes polysomnography, deep brain stimulation, and more
- Reviews sleep-tracking devices, EEG and telemetry
- Covers artificial intelligence and big data in analysis
Graduate students in biological and biomedical sciences, neurologists, sleep scientists, neuroscientists, neurobiologists, post-doctoral fellows, researchers, residents, fellows. A wide range of academic and professional disciplines (scientist, students, and professionals) in: Cell biology, Experimental biology, Human genetics, Molecular biology, Neuroscience, Pharmacology
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- Contributors
- Foreword
- Acknowledgments
- Chapter 1. Definitions and measurements of the states of vigilance
- The sleep-wake cycle
- General anesthesia
- States of hypometabolism
- Conclusion
- Chapter 2. Polysomnography in humans and animal models: basic procedures and analysis
- Introduction
- Polysomnography
- Polysomnography in humans
- Polysomnography in animal models
- Quantitative electroencephalogram analysis
- Conclusion
- Chapter 3. Electrophysiological studies and sleep-wake cycle
- Introduction
- Electrophysiology and sleep-wake regulatory systems
- Extracellular recording: basic procedure
- Juxtacellular recording-labeling
- Basic procedure
- Juxtacellular recording-labeling and sleep-wake studies
- Conclusions
- Chapter 4. Physiologic systems dynamics, coupling and network interactions across the sleep-wake cycle
- Physiologic dynamics across sleep stages and circadian phases
- Physiological systems interactions during wake and sleep
- Chapter 5. Deep brain stimulation for understanding the sleep-wake phenomena
- Deep brain stimulation for the treatment of sleep disorder in several thalamocortical dysrhythmia pathologies
- Neuronal mechanisms underlying deep bran stimulation
- Pharmacological intervention of histone deacetylase enzymes for the treatment of sleep disorders during deep brain stimulation
- Chapter 6. Electroencephalography power spectra and electroencephalography functional connectivity in sleep
- Quantitative electroencephalography
- Quantitative electroencephalography in normal sleep
- Quantitative electroencephalography in abnormal sleep
- Chapter 7. Optogenetics in sleep and integrative systems research
- Background
- Basics of optogenetics
- Optogenetics versus chemical or electrical stimulation techniques
- Potential disadvantages of optogenetic
- Applications of optogenetics in sleep research
- Surgical procedures
- Sample protocol for optogenetics in sleep research
- Experimental variants
- Conclusions
- Chapter 8. Immunohistochemical analysis and sleep studies: some recommendations to improve analysis data
- Introduction
- Cell markers and sleep
- Immunohistochemistry and sleep studies
- Statistical considerations when analyzing immunoreactive cells
- Pseudoreplication
- Conclusions
- Chapter 9. Wireless vigilance state monitoring
- Measuring states of vigilance
- Wireless monitoring of vigilance states
- New opportunities offered by the wireless monitoring of the vigilance states
- Chapter 10. Wearable and nonwearable sleep-tracking devices
- Introduction
- Features
- Reliability, validity, and accuracy
- Utility and applications of wearables and nonwearables
- Assessing sleep health parameters
- Diagnosis of diseases and health conditions
- Using wearables to deliver interventions
- The use of wearables and nonwearables across the lifespan
- Conclusion
- Chapter 11. Clinical trial: imaging techniques in sleep studies
- Imaging in normal human sleep
- Imaging in nonrapid eye movement sleep
- Imaging in rapid eye movement sleep
- Conclusions and future directions
- Chapter 12. Objective questionnaires for assessment sleep quality
- Introduction
- Steps in scale construction
- A soupçon of test theory
- Reliability
- Validity
- Summary
- Chapter 13. Clinical psychoinformatics: a novel approach to behavioral states and mental health care driven by machine learning
- Introduction
- Overview of machine learning
- Clinical applications of machine learning approaches in the mental health field
- Limitations of machine learning approaches
- Future perspectives on the use of machine learning approaches
- Conclusions
- Index
- Edition: 1
- Published: October 9, 2021
- No. of pages (Paperback): 306
- No. of pages (eBook): 306
- Imprint: Academic Press
- Language: English
- Paperback ISBN: 9780323852357
- eBook ISBN: 9780323903349
EM
Eric Murillo-Rodriguez
Dr. Murillo-Rodríguez is a Psychologist and PhD in Biomedical Sciences, having completed his post-doctoral training at Harvard Medical School. He has served as editor of multiple journals such as The International Journal of Neuropsychopharmacology and PLoS ONE, among many others. He is a member of several scientific societies, including the Society for Neuroscience. He has received academic awards such as the Young Investigator Award from the World Federation of Sleep Research and Sleep Research Societies Society, and is a member of the National System of Researchers (Level 2) of the National Council of Science and Technology (México). He is also the author of The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy (Elsevier, May 2017).
Affiliations and expertise
Psychologist, Universidad Anáhuac Mayab, MexicoRead Methodological Approaches for Sleep and Vigilance Research on ScienceDirect