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Elsevier

Academic Press

  • Metalloproteins and Motor Proteins

    • 1st Edition
    • Volume 141
    • English
    Metalloproteins and Motor Proteins, Volume 141 focuses on recent advances in studying metalloproteins and motor proteins, along with their roles in different pathologies and drug-resistance. Chapters include Transcriptomic Analysis Reveals Zinc-Mediated Virulence and Pathogenicity in Multidrug-Resistant Acinetobacter baumannii, The Mechanistic Insights into Different Aspects of Promiscuity in Metalloenzymes, Role of Metal ion in ion channel Mechanisms, A model of microtubule depolymerization by kinesin-8 motor proteins, Metalloproteins and metalloproteomics in health and disease, Decoding Genetic and Pathophysiological Mechanisms in Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis: A Comparative Study of Differentially Expressed Genes and Implicated Pathways in Motor Neuron Disorders, and much more.Additional chapters cover Exploring the effect of disease causing mutations in metal binding sites of human ARSA in Metachromatic Leukodystrophy, Role of transmembrane proteins in regulating metalloproteins and motor proteins in human cancer, Role of transmembrane proteins in metalloproteins and motor proteinsin human neurogenesis, Role of transmembrane proteins in metalloproteins and motor proteins in human aging, Vesicle transport of metalloproteinases, Motor proteins and spermatogenesis, and much more.

  • Handbook of Digital Currency

    Bitcoin, Innovation, Financial Instruments, and Big Data
    • 2nd Edition
    • David Lee Kuo Chuen
    • English
    Handbook of Digital Currency: Bitcoin, Innovation, Financial Instruments, and Big Data, Second Edition offers readers new ways to learn about subjects outside their specialties and provides authoritative background and tools for those whose primary source of information is journal articles. Encompassing currencies, payment methods, and computer communication protocols, digital currencies are growing in use and importance. The book's comprehensive view of the field covers history, technical, IT, finance, economics, legal, tax, and the regulatory environment. For those coming from different backgrounds with different questions in mind, this new edition is an essential starting point.

  • Recent Trends in Fractional Calculus and Its Applications

    • 1st Edition
    • Praveen Agarwal + 2 more
    • English
    Recent Trends in Fractional Calculus and Its Applications addresses the answer to this very basic question: "Why is Fractional Calculus important?" Until recent times, Fractional Calculus was considered as a rather esoteric mathematical theory without applications, but in the last few decades there has been an explosion of research activities on the application of Fractional Calculus to very diverse scientific fields ranging from the physics of diffusion and advection phenomena, to control systems to finance and economics. An important part of mathematical modelling of objects and processes is a description of their dynamics.The term Fractional Calculus is more than 300 years old. It is a generalization of the ordinary differentiation and integration to noninteger (arbitrary) order. The subject is as old as the calculus of differentiation and goes back to times when Leibniz, Gauss, and Newton invented this kind of calculation. Several mathematicians contributed to this subject over the years. People like Liouville, Riemann, and Weyl made major contributions to the theory of Fractional Calculus. In recent decades the field of Fractional Calculus has attracted the interest of researchers in several areas, including mathematics, physics, chemistry, engineering, finance, and social sciences.

  • Error Control, Adaptive Discretizations, and Applications, Part 1

    • 1st Edition
    • Volume 58
    • English
    Error Control, Adaptive Discretizations, and Applications, Volume 58, Part One highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this release cover hp adaptive Discontinuous Galerkin strategies driven by a posteriori error estimation with application to aeronautical flow problems, An anisotropic mesh adaptation method based on gradient recovery and optimal shape elements, and Model reduction techniques for parametrized nonlinear partial differential equations.

  • Design and Applications of Microneedles in Drug Delivery and Therapeutics

    • 1st Edition
    • Prashant Kesharwani
    • English
    Design and Applications of Microneedles in Drug Delivery and Therapeutics details the design, characterization, and applications of this novel drug delivery system. Microneedles offer several advantages over traditional oral and parenteral approaches due to their ability to be fabricated and altered in shape, size and material type, and their convenience to be matched to specific treatment needs. This book covers the materials selection, design and fabrication approaches, and clinical translation of microneedles for a range of therapeutic applications, including cancer therapy, gene and vaccine delivery, wound healing, and more.This book is a forward-thinking resource for those working in the development of materials and devices for novel drug delivery.

  • Clinical Application of Repurposed Drugs

    • 1st Edition
    • Volume 207
    • English
    Clinical Application of Repurposed Drugs, Volume 207 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on Drug repurposing for viral disease, Drug repurposing for bacterial infections, Drug repurposing for parasitic protozoan diseases, Drug repurposing for fungal infections, Drug repurposing for treating anxiety and depression, Drug repurposing for personalized medicine, Drug repurposing for cancer, Drug Repurposing: A multi targeted approach to treat cardiac disease from existing classical drugs to modern drug discovery, and much more.Additional chapters cover Drug repurposing in MASLD and MASH-cirrhosis: targets and treatment approaches based on pathways analysis, Drug repurposing for respiratory infections, Drug repurposing for rare disease, Drug repurposing for neurological disorders, Drug repurposing for metabolic disorders: scientific, technological and economic issues, Drug repurposing for regenerative medicine and cosmetics: scientific, technological and economic issues, and Exploring Cutting-Edge Omics-Driven Strategies for Drug Repurposing – An Insight into the Tools of the Trade.

  • Terpene Synthases

    • 1st Edition
    • Volume 699
    • English
    Terpene Synthases, Volume 700 in the Methods in Enzymology series, continues the legacy of this highly respected laboratory standard with its first dedicated collection on this important family of enzymes. Terpene synthases are a diverse set of enzymes that use exquisite mechanisms to form complex (poly)cyclic hydrocarbon skeletons. Chapters in this new volume include Structural analysis by X-ray crystallography and cryo-EM, Understanding mechanisms using stable isotopes, substrate analogs, or computational tools, Engineering fusion enzymes, Ancestral terpene cyclases, as well as the Sequence, structure, and function of non-canonical terpene synthases.

  • Prosopis Juliflora

    Attributes, Impact, Utilization
    • 1st Edition
    • Pratiksha Patnaik + 2 more
    • English
    Prosopis (Prosopis juliflora) is a xerophyte which, in its native habitats has been a desert plant. As long as it was confined to that habitat, P. juliflora was a great resource, improving the region’s micrometeorology, binding its sandy soil, and providing shelter, fuel, feed, food, medicines, and cosmetics to the people of such regions. In particular, for the economically weaker inhabitants, P.juliflora was a lifeline.But when P. juliflora was indiscriminately introduced in other regions of the world in a hope to derive similar benefits from it, things began to go awry. Indeed, among the invasive species of plants which are spreading at an alarming rate in the tropical and sub-tropical regions of the world, P.juliflora is arguably the most hardy and resilient. It is growing so explosively that it even enters roads and homes, driving humans out of their dwellings. The resulting damage to biodiversity is enormous. This book highlights the dual role played so far by P. juliflora and itemizes the facets that make it a blessing in some contexts and a bane in other contexts.Authored by leading experts in the field, Prosopis juliflora: Attributes, Impact, Utilization is the first title of its kind to comprehensively discuss this hardy plant species. It will be an essential read for students, researchers and governmental agencies interested in plant biology, forestry, plant ecology, invasive plant species and environmental science.

  • Mechanics in Development and Disease

    • 1st Edition
    • Volume 160
    • English
    Mechanics in Development and Disease, Volume 160 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Gut developmental mechanics, Long bone developmental mechanics, Cranial plate fusion developmental mechanics, Mechanobiology and vasculogenesis, Morphogenesis and mechanics of the developing inner ear, Morphogenesis and mechanics of body wall closure in mammals, Salivary bud developmental mechanics, Lateral plate mesoderm developmental mechanics, Biomechanics of human embryo implantation, gastrulation, and organ formation, Mechanics of lung development across species, Mechanics early development in vertebrates.

  • Peritoneal Tumor Microenvironment of Cancers on Cancer Hallmarks

    Perspectives of Translational Medicine
    • 1st Edition
    • Yong Sang Song + 6 more
    • English
    Peritoneal Tumor Microenvironment of Cancers on Cancer Hallmarks: Perspectives of Translational Medicine provides readers with cutting-edge knowledge on tumor microenvironment. By exploring multiple aspects on tumor microenvironment, it gives an integrative insight on cancer diseases ranging from diagnosis to prediction of prognosis and individualized treatment. The book discusses topics such as clinical significance of tumor microenvironment, tumorigenesis and cancer progression, histopathological features of cancer in peritoneum, immune cells in tumor, exosomal cell-to-cell interactions, and therapeutic approaches to target tumor microenvironment. In addition, it discusses tumor evolution during chemotherapy and metastasis and future perspectives on identification and validation of biomarkers using liquid biopsy. This book is a valuable resource for cancer researchers, oncologists, medical doctors, and several members of biomedical field who want to understand the complex microenvironment of peritoneal tumors.

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