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Elsevier

Academic Press

  • Redox Signaling

    • 1st Edition
    • Volume 162
    • English
    Advances in Cancer Research, Volume 162 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • A Practical Guide for Finding Interventions That Work for Autistic People

    Diversity-Affirming Evidence-Based Practice
    • 2nd Edition
    • Susan M. Wilczynski
    • English
    A Practical Guide for Finding Interventions that Work for Autistic People: Diversity Affirming Evidence-Based Practice, second edition, provides a socially valid, culturally sensitive, and person-centered resource to aid practitioners in guiding the selection of effective interventions. By providing multiple illustrative examples, practitioners will learn to use their professional judgment to integrate the best available evidence with client values and context. The second edition includes new chapters on diversity affirmation and cultural adaptations of interventions, quality of life, self-determination, guided decision-making, and ethics as foundational skills for identifying effective, socially valid interventions that are delivered with compassion and assent/consent.

  • Microbial Genomics: Clinical, Pharmaceutical, and Industrial Applications

    • 1st Edition
    • Huseyin Tombuloglu + 1 more
    • English
    Microbial Genomics: Clinical, Pharmaceutical and Industrial Applications focuses on the various applications of microbial genomics in clinical, pharmaceutical, and industrial fields. The book consists of four parts devoted to bacterial, viral, and fungal genomics, as well as their applications in clinical, pharmaceutical, and industrial fields. Chapters are written by experts in their respective disciplines and are tightly organized with an introduction to detailed descriptions, available software implementation, applications, advanced topics, summaries, analytic questions, exercises, and suggested readings. Throughout this book, the latest genomics and biotechnological developments and discoveries as well as open problems and future challenges on microbial genomics are highlighted. Readers will be introduced to state-of-the-art developments and trends of microbial genomics, its clinical, pharmaceutical, and industrial applications.

  • The Rose and Mackay Textbook of Autoimmune Diseases

    • 7th Edition
    • M. Eric Gershwin + 2 more
    • English
    **Selected for 2025 Doody’s Core Titles® with "Essential Purchase" designation in Allergy/Clinical Immunology**The Rose-Mackay Textbook of Autoimmune Diseases, Seventh Edition is a comprehensive reference that emphasizes the "3 P’s" of 21st Century medicine: precision, prediction, and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients.This new edition continues its success with 75% of the content revised, updated, or completely new. This edition is a valuable resource to clinicians involved in the diagnosis and treatment of autoimmune disease, as well as to scientists who want to follow developments in the field.

  • Diagnostic, Prognostic, and Therapeutic Role of MicroRNAs in Head and Neck Cancer

    • 1st Edition
    • Ashok Kumar + 3 more
    • English
    Diagnostic, Prognostic and Therapeutic Role of MicroRNAs in Head and Neck Cancer provides detailed information on various miRNA-based approaches for the diagnosis, prognosis, and treatment of HNSCC. The book encompasses various miRNA-based point-of-care diagnostics and drug delivery systems for HNSCC, along with information on clinical trials for improved clinical outcomes in HNSCC patients. In addition, it provides a comprehensive overview of currently available miRNAs associated with HNSCC and their extensive application for early diagnosis, prognosis, and treatment. Scientists and clinicians looking to win the battle against HNSCC will benefit from the book's sections on early diagnosis to improve treatment, increase treatment response rates, and reduce mortality rates. Recently, miRNA-based diagnostics and therapeutics have gained considerable attention among the scientific community. MiRNAs are known to have great potential as biomarkers for early diagnosis, prediction, and prognosis of HNSCC, and play a role in development of targeted gene therapy.

  • Alzheimer's Disease Research Guide

    Animal Models for Understanding Mechanisms and Medications
    • 1st Edition
    • Takaomi C. Saido
    • English
    Alzheimer's Disease Research Guide: Animal Models for Understanding Mechanisms and Medications provides researchers with a comprehensive guide, detailing every aspect of Alzheimer's Disease research, including chapters on neuroinflammation, immunotherapy, biomarkers, and animal modeling. This book begins with historical perspectives of both pathological chronology and pathological biochemistry in relation to Alzheimer’s disease. Other chapters review Amyloidogenic AB and Non-Amyloidogenic tau and Metabolism of AB major components to the research and understanding of Alzheimer’s research. The book concludes with specific treatment chapters including how to develop safe, effective, and inexpensive medications and the application of genome editing to the treatment of Familial Alzheimer's Disease.Written by world renowned expert in Alzheimer’s research, this book is a valuable resource for all researchers.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 128
    • English
    Advances in Applied Microbiology, Volume 128 continues the comprehensive reach of this widely read and authoritative review source in microbiology where users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

  • The Science and Art of Sensory Processing Sensitivity

    • 1st Edition
    • Bianca P. Acevedo
    • English
    The Science and Art of Sensory Processing Sensitivity provides an up-to-date and novel scientific perspective on the biologically based Sensory Processing Sensitivity (SPS) trait— which is associated with enhanced awareness, depth of cognitive processing, and heightened responsivity to the environment and other individuals. This second volume by B.P. Acevedo, following “The Highly Sensitive Brain,” takes a scientific perspective on its exploration of SPS, but adds to the existing body of literature on high sensitivity by including an enhanced discussion on the proposed mechanisms linking it with depression, anxiety, and burnout.In addition, this second volume explores SPS’ relationship to other relevant personality traits, such as the Big Five, creativity, and sensation seeking; and sheds light on how their varying combinations give rise to different outcomes for highly sensitive persons (HSPs). A unique contribution of this volume is its detailed examination of the role of culture, gender, biology, aging, and the environment (including the workplace) on the expression (or repression) of high sensitivity.Also, unlike previous books, this volume takes a broad perspective on outcomes related to being highly sensitive to shine a light on the non-trivial issue plaguing many HSPs: diminished quality of life, happiness, and well-being. As such, a major contribution of the second volume on the science of SPS, is its extensive description of scientifically-based techniques that might improve the quality of life for those with high SPS.Thus, this volume may appeal to a wide audience, including both HSPs and those in their social network (friends, partners, physicians, parents, educators, and clinicians) who wish to better understand SPS, those with the trait, and how to enhance well-being among the highly sensitive.

  • Decision-Making Models

    A Perspective of Fuzzy Logic and Machine Learning
    • 1st Edition
    • Tofigh Allahviranloo + 2 more
    • English
    Decision Making Models: A Perspective of Fuzzy Logic and Machine Learning presents the latest developments in the field of uncertain mathematics and decision science. The book aims to deliver a systematic exposure to soft computing techniques in fuzzy mathematics as well as artificial intelligence in the context of real-life problems and is designed to address recent techniques to solving uncertain problems encountered specifically in decision sciences. Researchers, professors, software engineers, and graduate students working in the fields of applied mathematics, software engineering, and artificial intelligence will find this book useful to acquire a solid foundation in fuzzy logic and fuzzy systems.Other areas of note include optimization problems and artificial intelligence practices, as well as how to analyze IoT solutions with applications and develop decision-making mechanisms realized under uncertainty.

  • Redox Signaling in Wound Healing in Elderly Populations: Theoretical Basis, Part 1

    • 1st Edition
    • Volume 2
    • English
    Redox Signaling in Wound Healing in Elderly Populations: Theoretical Basis, Part 1 deals with wounds in different types and locations (diabetic, ischemic, post-operational) in subcellular and macro dimensions, examine their relationship with aging aim to target deteriorating redox signaling cascades, and will also focus on promising therapeutic approaches. Understanding the indication for the use of new therapeutics targeting the illuminated pathways in wound healing will help adjust treatment regimens befitting modern medicine. Ineffective redox adaptation and disseminated oxidative injury are the hallmarks of continuing oxidative stress. However, oxidative stress cannot be simply described as the imbalance between ROS formation and antioxidant defense capacity; it also covers impairment in redox sensing and signaling pathways. The term oxidative stress is an expression that is losing its use in modern redox biology. It is now an accepted fact that ROS cannot be described as an apparent enemy or friend. Its optimum level modulates signal transduction and stress responses by acting as a second messenger for redox-sensitive cascades. Redox-dependent second messengers are generated in subcellular locations according to specific rules and regulations. Their appearance depends on cellular needs in response to external and internal stimuli variations. A good understanding of the wound healing cascades, which deteriorate especially in advancing ages, is critical in developing the most appropriate approach. To understand the redox signaling mechanisms and healing cascades in wound healing, to pioneer new pharmacoactive drugs that can be developed based on these mechanisms, to reveal the deteriorating dynamics in the elderly patient group, and to propose new treatment methods suitable for the advanced age group.

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