
Profiles of Drug Substances, Excipients, and Related Methodology
- 1st Edition, Volume 50 - January 23, 2025
- Imprint: Academic Press
- Editor: Abdulrahman Al-Majed
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 3 4 4 8 3 - 1
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 3 4 4 8 4 - 8
Profiles of Drug Substances, Excipients, and Related Methodology, Volume 50 includes comprehensive profiles of four drug compounds: Sofosbuvir, Nateglinide, Linagliptin, and Droned… Read more

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Request a sales quoteProfiles of Drug Substances, Excipients, and Related Methodology, Volume 50 includes comprehensive profiles of four drug compounds: Sofosbuvir, Nateglinide, Linagliptin, and Dronedarone, providing comprehensive knowledge on their physical and chemical properties, synthesis and degradation pathways, analytical techniques for identification and quantification, separation methods, and pharmacology of drug substances. Finally, this volume includes a review article related to the Applications of Cyclodextrins in Pharmaceutical and Related Fields, along with a chapter on Fenamates Degradation. This information is highly valuable to professionals in the field, but having it all in one place is a great benefit to readers.
The Profiles series encompasses five review articles and database compilations on various topics, including the physical profiles, analytical profiles, ADME profiles, methodologies related to the characterization, and methods of chemical synthesis of drug substances and excipients.
The Profiles series encompasses five review articles and database compilations on various topics, including the physical profiles, analytical profiles, ADME profiles, methodologies related to the characterization, and methods of chemical synthesis of drug substances and excipients.
- Provides synthesis and pathways of physical or biological degradation of selected drug substances
- Offers a comprehensive review of the biological, chemical, physical characteristics, and pharmacology of certain drug substances
- Describes nearly all analytical methods available in the literature used to identify and quantify drug substances
- Offers applications of certain materials in pharmaceuticals and related fields
- Provides a cumulative index for each volume in the series
Pharmacists; Pharmaceutical, medicinal, and analytical chemists; Pharmacologists; physicians; Dentist
- Cover image
- Title page
- Table of Contents
- Series Page
- Copyright
- Contributors
- Preface
- Chapter One: Sofosbuvir: A comprehensive profile
- Abstract
- Abbreviations
- 1 Description
- 2 Mode of action
- 3 Pharmacokinetics
- 4 Indications
- 5 Synthesis
- 6 Physical characteristics
- 7 Methods of analysis
- Acknowledgment
- References
- Chapter Two: Nateglinide: A comprehensive profile
- Abstract
- 1 General information
- 2 Physical characteristics
- 3 Uses and applications
- 4 Stability
- 5 Preparation of nateglinide
- 6 Impurities
- 7 Methods of analysis
- 8 Pharmacology
- References
- Chapter Three: Linagliptin: A comprehensive profile
- Abstract
- Abbreviations
- 1 Description
- 2 Mode of action
- 3 Pharmacokinetics
- 4 Indications
- 5 Synthesis
- 6 Physical characteristics
- 7 Methods of analysis
- Acknowledgment
- References
- Chapter Four: Dronedarone a comprehensive drug profile
- Abstract
- 1 Description
- 2 Methods of preparation of Dronedarone
- 3 Physical characteristics
- 4 Reported analytical method for Dronedarone
- 5 Stability
- 6 Clinical applications
- Acknowledgment
- References
- Chapter Five: Cyclodextrins and their applications in pharmaceutical and related fields
- Abstract
- 1 Introduction
- 2 Classifications and properties
- 3 CD inclusion complex formation and complexation techniques
- 4 Industrial applications of CDs
- 5 Future prospects
- 6 Conclusion
- References
- Chapter Six: Degradation of fenamates
- Abstract
- Abbreviations
- 1 Introduction
- 2 Modes of drug degradation
- 3 Basic chemical structure of fenamates
- 4 Degradation of NSAIDS
- 5 Degradation of fenamates
- 6 Conclusion
- References
- Cumulative Index
- Edition: 1
- Volume: 50
- Published: January 23, 2025
- Imprint: Academic Press
- No. of pages: 454
- Language: English
- Hardback ISBN: 9780443344831
- eBook ISBN: 9780443344848
AA
Abdulrahman Al-Majed
Professor Abdulrahman AlMajed obtained a Bachelor of Pharmaceutical Sciences from College of Pharmacy, King Saud University, Riyadh, Saudi Arabia in 1990 and a Ph.D. in the field of Pharmaceutical analytical Chemistry from the University of Bradford, UK, in 1997. He also received a Bachelor of Legislation from College of Legislation, Imam Mohammed Bin Saud University, Riyadh, Saudi Arabia. He was appointed as assistance professor in Pharmaceutical Chemistry Department at College of Pharmacy, King Saud University in 1998. He was promoted to the rank of associated professor in 2003. He was a head of Pharmaceutical Chemistry Department (2005-2019) (2015-2017). Since 2009, he is full professor of Pharmaceutical Analytical Chemistry. He was assistance secretary of Scientific Council at King Saud University and he is presently a member of Scientific Council in Princess Nourah Bint Abdul Rahman University and in Jouf University, Saudi Arabia. He also a member of Medical and health Sciences Committee of Qualification Recognition in Ministry of Education and a member of Patent Lawsuits Committee in Saudi Arabia. He is a member of several scientific and social Committees. He participated in several national and international conferences and symposia. Prof. Almajed has taught courses in the field of Pharmaceutical Analysis at both the undergraduate and postgraduate levels at College of Pharmacy. He is recently appointed as the Editor-In-Chief of the book series Profiles of Drug Substances, Excipients, and Related Methodology. He published 10 chapters in the series. Dr. AlMajed published over 65 research papers in the field of Pharmaceutical Analysis. His research is focused on determination and validation of pharmaceutical compounds in dosage forms or/and in biological fluids by analytical techniques including: HPLC, electrophoresis, spectrophotometry, spectrofluorometry, voltammetry. His research also includes resolution and quantitation of the R-(-)- and S-(+)- enantiomers of pharmaceutical compounds in dosage forms or/and in biological fluids using chiral stationary phases.
Affiliations and expertise
Professor, Pharmaceutical Chemistry Department, College of Pharmacy, King Saud University, Saudi ArabiaRead Profiles of Drug Substances, Excipients, and Related Methodology on ScienceDirect