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Microbiota-Gut-Brain Axis and CNS Disorders

Recent Progress and Perspectives

  • 1st Edition - January 21, 2025
  • Latest edition
  • Editors: Neeraj Mishra, Anoop Kumar
  • Language: English

Microbiota-Gut-Brain Axis and CNS Disorders: Recent Progress and Perspectives on Human Disease summarizes the main findings on gut-brain axis in different types of CNS disord… Read more

Description

Microbiota-Gut-Brain Axis and CNS Disorders: Recent Progress and Perspectives on Human Disease summarizes the main findings on gut-brain axis in different types of CNS disorders, providing a complete overview of the field. The content helps unravel the complex interactions of the microbiota-gut-brain-axis in CNS disorders to pave a better understanding of microbiota-mediated pathogenesis, avenues for noninvasive prognosis, and therapeutic possibilities leveraging microbiota-gut-brain-axis modulations. Coverage includes the role of the microbiota-gut-brain axis and gut virome on human diseases including Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Disease, Depression and Anxiety, Autism Spectrum Disorder, Multiple Sclerosis, Stroke, and others.

This book will satisfy the urgent need for a broader view of the current associations between gut microbiota alterations and development of CNS disorders, including the use of novel therapeutic approaches for restoring the correct intestinal bacteria content. It is the perfect reference for translational and clinical gut and microbiome researchers tackling the challenges of delivering genes and drugs in a more targeted and efficient manner for the treatment of CNS disorders.

Key features

  • Discusses the development of both health and disease in interdisciplinary research involving gut microbiology
  • Provides an understanding the role of Microbiome-Gut-Brain axis in neurodegenerative and neurodevelopmental diseases, including central nervous system (CNS) malignancies
  • Delivers a compilation of current clinical studies to further investigate the role of diet in varying neurological disorders

Readership

Graduates, translational and clinical gut, microbiome, and respiratory researchers tackling the challenges of delivering drugs and genes in a more targeted and efficient manner for the treatment of CNS disorders, Undergraduate and post graduate students from various disciplines such as pharmacy, microbiology, immunology, pharmacology, biotechnology, and health sciences

Table of contents

1. Introduction: An overview of Microbiota-Gut- Brain Axis

2. Role of Microbiota-Gut- Brain Axis in Alzheimer disease and possible interventions

3. Role of Microbiota Gut- Brain axis in Parkinson’s disease

4. Role of Microbiota-Gut- Brain Axis in Huntington’s disease and possible interventions

5. Role of Microbiota-Gut- Brain Axis in depression and anxiety

6. Role of microbiome- Gut Brain axis in autism spectrum disorder (ASD)

7. Role of Microbiota- Gut brain axis in autoimmunity and Multiple Sclerosis

8. Role of Microbiome Gut- Brain axis in stress

9. Role of Microbiota- Gut Brain Axis in epilepsy and possible interventions

10. Role of Microbiota- Gut Brain Axis in migraine and possible interventions

11. Role of Microbiota- Gut Brain Axis in stroke and possible interventions

12. Role of Microbiota- Gut Brain Axis in brain infections and possible interventions

13. Role of Microbiome Gut- Brain axis in brain disorders

14. Role of GUT microbiota in neuropsychiatric and neurological disorders

15. Role of Microbiota- Gut Brain Axis in Obesity on Cognitive Functions and Mood

16. Role of Microbiota- Gut Brain Axis on Neurotransmitters modulation

17. Role of gut virome and mycobiome in neurological disorders

18. Role of nutraceuticals in neurological diseases

19. Future prospective of Microbiome- Gut brain axis for treatment of CNS disorders

Product details

  • Edition: 1
  • Latest edition
  • Published: January 29, 2025
  • Language: English

About the editors

NM

Neeraj Mishra

Neeraj Mishra is Professor and Head of the Department of Pharmaceutics at the Amity Institute of Pharmacy, Amity University Madhya Pradesh, Gwalior, India. His academic work focuses on novel drug delivery systems, including localized, targeted, and controlled delivery approaches using nanocarrier and microparticle-based technologies. His research interests encompass therapies for cancer and neurodegenerative disorders, and he has extensive experience in teaching, research supervision, and scholarly publishing. He has also contributed to innovation in pharmaceutical sciences through intellectual property development and collaborative academic activities. Through his research and educational initiatives, he supports the advancement of drug delivery strategies and pharmaceutical research.

Affiliations and expertise
Professor & Head, Department of Pharmaceutics, Amity Institute of Pharmacy, Amity University, Gwalior, Madhya Pradesh, India

AK

Anoop Kumar

Anoop Kumar is Assistant Professor in the Department of Pharmacology at the Delhi Institute of Pharmaceutical Sciences and Research (DIPSAR), Delhi Pharmaceutical Sciences and Research University (DPSRU), Government of NCT of Delhi, India. He has held academic and research positions in pharmaceutical education, translational research, and the pharmaceutical industry. His professional activities include teaching, research, editorial service, ethics committee responsibilities, and engagement with professional organizations. His research interests include drug repurposing, meta-analysis of clinical trials, network pharmacology, pharmacoeconomics, pharmacovigilance, and experimental pharmacology. He has contributed to scientific publishing and research initiatives that support evidence-based approaches to drug discovery, development, and healthcare decision-making.

Affiliations and expertise
Assistant Professor, Department of Pharmacology, Delhi Institute of Pharmaceutical Sciences and Research (DIPSAR), Delhi, Pharmaceutical Sciences and Research University (DPSRU), Government of NCT of Delhi, New Delhi, India

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