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Elsevier

Academic Press

  • The Discovery of New Medicines in Academia

    • 1st Edition
    • Volume 100
    • English
    The Discovery of New Medicines in Academia, Volume 100 highlight examples of discoveries originating in academia that have been successfully translated into promising therapeutics that have advanced into clinical trials. Chapters in this release cover Design and Discovery of Itaconate prodrugs for Alopecia Areata, Hydroxyl-Dendrimer Delivery System for Neurological Disease, Development of allosteric modulators of G protein-coupled receptors for Psychiatric Disease, Targeting the constitutively active ERK1/2 signaling kinase for cancer, mRNA reprogramming of myeloid cells for tumor immunotherapy, Development of novel drugs targeting protein-protein interactions, and much more.Additional sections cover Neuro-steroids and analogs for the treatment of epilepsy, Development of inhibitors of eukaryotic translation, Discovery/developmen... of antiviral, anticancer and/or anti-inflammatory agents, Discovery of novel anti-infective agents, Targeting proliferating cell nuclear antigen (PCNA) for cancer, and Implementation and Evolution of Quantitative Systems Pharmacology to Patient Digital Twins and Biomimetic Twins.

  • Advances in Agronomy

    • 1st Edition
    • Volume 187
    • English
    Advances in Agronomy, Volume 187, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 85
    • English
    Advances in Microbial Physiology, Volume 85 in this ongoing serial, highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Topics of interest in this update include The genetic basis of predation by myxobacteria, Vancomycin susceptibility and VISA in Staphylococcus aureus, Cytochrome bd-type oxidases and environmental stressors in microbial physiology, Bacterial heme-containing sensor proteins, Algal hemoglobins, Inter-species interactions in polymicrobial infections, Utilization of Low Methane Concentrations by Methanotrophs, and Role of sulfidogenic members of the gut microbiota in human disease.

  • Hormones and Reproduction of Vertebrates, Volume 1

    Fishes
    • 2nd Edition
    • David O. Norris + 1 more
    • English
    Hormones and Reproduction of Vertebrates, Volume 1: Fishes is the first of five second-edition volumes representing a comprehensive and integrated overview of hormones and reproduction in fishes, amphibians, reptiles, birds, and mammals. The book includes coverage of endocrinology, neuroendocrinology, physiology, behavior, and anatomy of fish reproduction. It provides a broad treatment of the roles of pituitary, thyroid, adrenal, and gonadal hormones in all aspects of reproduction, as well as descriptions of major life history events. New to this edition is a concluding assessment of the effect of environmental influences on fishes.Initial chapters in this book broadly examine sex determination, reproductive neuroendocrinology, stress, and hormonal regulation as they relate to testicular and ovarian development and function. Subsequent chapters examine hormones and reproduction of specific taxa, especially teleosts, with additional coverage of reproductive cycles of agnathan, chondrichthyan, and sarcopterygian fishes. The book concludes with an examination of the environmental influences on hormones and reproduction of fishes, including endocrine-disrupting chemicals, microplastic particles, and climate change.

  • Blood-Brain Barrier

    • 1st Edition
    • Volume 126
    • English
    Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Cannabidiol in Neurology and Psychiatry

    • 1st Edition
    • Volume 177
    • English
    Cannabidiol in Neurology and Psychiatry, Volume 177 in the International Review in Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topic such as Historical perspective on the therapeutic potential of cannabidiol, Cannabidiol: pharmacodynamics pharmacokinetic, Cannabidiol and Alzheimer’s disease, Cannabidiol on anxiety disorders, Cannabidiol on psychosis, Cannabidiol on autism spectrum disorders, Cannabidiol in Epilepsy, Cannabidiol in Ischemia/stroke, Cannabidiol in Depression, Cannabidiol and Abuse of drugs, and much more.Additional chapters cover Cannabidiol in fear response and PTSD, Cannabidiol and Pain. and Cannabidiol and Parkinson’s disease.

  • Biophysical Approaches for the Study of Membrane Structure Part B

    • 1st Edition
    • Volume 701
    • English
    Biophysical Approaches for the Study of Membrane Structure, Part B, Volume 701 explores lipid membrane asymmetry and lateral heterogeneity. A burst of recent research has shown that bilayers whose leaflets differ in their physical properties—such as composition, phase state, or lateral stress—exhibit many fascinating new characteristics, but also pose a host of challenges related to their creation, characterization, simulation, and theoretical description. Chapters in this new release include Characterization of domain formation in complex membranes: Analyzing the bending modulus from simulations of complex membranes, The density-threshold affinity: Calculating lipid binding affinities from unbiased Coarse-Grain Molecular Dynamics simulations, and much more.Additional sections cover Uncertainty quantification for trans-membrane stresses and moments from simulation, Using molecular dynamics simulations to generate small-angle scattering curves and cryo-EM images of proteoliposomes, Binary Bilayer Simulations for Partitioning Within Membranes, Modeling Asymmetric Cell Membranes at All-atom Resolution, Multiscale remodeling of biomembranes and vesicles, Building complex membranes with Martini 3, Predicting lipid sorting in curved bilayer membranes, Simulating asymmetric membranes using P21 periodic boundary conditions, and many other interesting topics.

  • Personalized Epigenetics

    • 2nd Edition
    • Trygve Tollefsbol
    • English
    Personalized Epigenetics, Second Edition discusses the core translatability of epigenetics to health management of individuals who have unique variations in their epigenetic signatures that can guide both disorder and disease prevention and therapy. Fully updated and revised, this new edition details inter-individual variability in the major epigenetic process in humans consisting of DNA methylation, histone modifications, noncoding RNA, and the diagnostic, prognostic, and therapeutic potential of the field. It also reviews the impact of the environment on epigenetic variations among individuals and the role of pharmacology and drug development in personalized epigenetics.Most importantly, the text covers personalized epigenetics from a disease-oriented perspective, presenting chapters that provide advances in widespread disorders or diseases, including diabetes, cancer, autoimmune disorders, obesity, cardiovascular diseases, neurological disorders, and pain management.

  • Hormones and Reproduction of Vertebrates, Volume 2

    Amphibians
    • 2nd Edition
    • David O. Norris + 1 more
    • English
    Hormones and Reproduction of Vertebrates, Volume 2: Amphibians is the second of five second-edition volumes representing a comprehensive and integrated overview of hormones and reproduction in fishes, amphibians, reptiles, birds, and mammals. The book covers endocrinology, neuroendocrinology, physiology, behavior, and the anatomy of amphibian reproduction. It provides a broad treatment of the roles of pituitary, thyroid, adrenal, and gonadal hormones in all aspects of reproduction, as well as descriptions of major life history events. New to this edition is a concluding assessment of the effect of environmental influences on amphibians.This book is designed to provide a readable, coordinated description of reproductive basics in amphibians, as well as an introduction to the latest trends in reproductive research and a presentation of our understanding of reproductive events gained over the past decade. It may serve as a stand-alone reference for researchers and practitioners in the field of herpetology or as one of five coordinated references aligned to provide topical treatment across vertebrate taxa for researchers, practitioners, and students focused on vertebrate endocrinology.

  • The Neurophysiology of Silence (C): Creativity, Aesthetic Experience and Time

    • 1st Edition
    • Volume 287
    • English
    Neurophysiology of Silence: Consciousness and Self Awareness, Volume 284 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

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