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Elsevier

Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

  • Transport Properties of Chemicals and Hydrocarbons

    Viscosity, Thermal Conductivity, and Diffusivity for more than 7800 Hydrocarbons and Chemicals, Including C1 to C100 Organics and Ac to Zr Inorganics
    • 1st Edition
    • Carl L. Yaws
    • English
    Carl Yaws, a leading authority on chemical compounds in the chemical engineering field, has done it again. In Transport Properties of Chemicals and Hydrocarbons -- an essential volume for any chemist or chemical engineer’s library -- he has amassed over 7,800 organic and inorganic chemicals, and hydrocarbons. Spanning gases, liquids and solids, and covering all critical properties (including viscosity, thermal conductivity, and diffusion coefficient), this volume represents more properties on more chemicals than any single work of its kind.

  • Principles of Surface-Enhanced Raman Spectroscopy

    and Related Plasmonic Effects
    • 1st Edition
    • Eric Le Ru + 1 more
    • English
    SERS was discovered in the 1970s and has since grown enormously in breadth, depth, and understanding. One of the major characteristics of SERS is its interdisciplinary nature: it lies at the boundary between physics, chemistry, colloid science, plasmonics, nanotechnology, and biology. By their very nature, it is impossible to find a textbook that will summarize the principles needed for SERS of these rather dissimilar and disconnected topics. Although a basic understanding of these topics is necessary for research projects in SERS with all its many aspects and applications, they are seldom touched upon as a coherent unit during most undergraduate studies in physics or chemistry. This book intends to fill this existing gap in the literature. It provides an overview of the underlying principles of SERS, from the fundamental understanding of the effect to its potential applications. It is aimed primarily at newcomers to the field, graduate students, researchers or scientists, attracted by the many applications of SERS and plasmonics or its basic science. The emphasis is on concepts and background material for SERS, such as Raman spectroscopy, the physics of plasmons, or colloid science, all of them introduced within the context of SERS, and from where the more specialized literature can be followed.

  • Scientific Data Ranking Methods

    Theory and Applications
    • 1st Edition
    • Volume 27
    • English
    This volume presents the basic mathematics of ranking methods through a didactic approach and the integration of relevant applications. Ranking methods can be applied in several different fields, including decision support, toxicology, environmental problems, proteomics and genomics, analytical chemistry, food chemistry, and QSAR.

  • Advances in Flow Injection Analysis and Related Techniques

    • 1st Edition
    • Volume 54
    • English
    The concept of flow injection analysis (FIA) was first proposed in 1975 by Ruzicka and Hansen, and this initiated a field of research that would, over more than three decades, involve thousands of researchers, and which has to date resulted in close to 20,000 publications in the international scientific literature. Since its introduction, a number of books, including some specialized monographs, have been published on this subject with the latest in 2000.However, in this decade there has been a number of significant advances in the flow analysis area, and in particular in sequential injection analysis (SIA) techniques, and more recently with the introduction of Lab on a Valve (LOV) and bead injection flow systems. This book aims to cover the most important advances in these new areas, as well as in classical FIA, which still remains the most popular flow analysis technique used in analytical practice. Topics covered in the 23 chapters include the fundamental and underlying principles of flow analysis and associated equipment, the fluid-dynamic theory of FIA, an extensive coverage of detection methods (e.g. atomic and molecular spectrometry, electroanalytical methods). In addition, there are several chapters on on-line separation (e.g. filtration, gas diffusion, dialysis, pervaporation, solvent and membrane extraction, and chromatography), as well as on other sample pretreatment techniques, such as digestion. The book also incorporates several chapters on major areas of application of flow analysis in industrial process monitoring (e.g food and beverages, drugs and pharmaceuticals), environmental and agricultural analysis and life sciences. The contributing authors, who include the founders of flow injection analysis, are all leading experts in flow analytical techniques, and their chapters not only provide a critical review of the current state of this area, but also suggest future trends.

  • Electrocorrosion and Protection of Metals

    General Approach with Particular Consideration to Electrochemical Plants
    • 1st Edition
    • Joseph Riskin
    • English
    Electrocorrosion, the corrosion of metallic constructions by external currents, is the most significant factor in conductive aggressive environments. Corrosion of underground and underwater metal constructions by stray currents has been comprehensively studied in the past decades and is considered here only in the form of a review. The primary attention is on corrosion, by external anodic (mainly) and cathodic currents, of metal constructions in the highly aggressive environments typical for electrochemical plants, where penetration of the external currents (leakage currents) from the electrolytic baths into metal constructions is unavoidable.A new approach to the problem of electrocorrosion protection of passive structural metals is considered in this book, keeping the metals attacked by external currents in the boundaries of their passive field. The systems, developed in accordance with this approach, are based on the modification of existing and elaboration of new methods of electrocorrosion protection. These systems take into account corrosion and electrochemical characteristics of the aggressive media (redox potential, conductivity etc.) and of the passive metal (corrosion and activation potentials, current density in a passive state, etc) as well as the sizes and distribution character of the external currents.The book covers analysis of leakage current distributions in electrochemical plants, their influence, methods to estimate corrosion stability of metallic structures subject to external currents and presents many concrete examples of the successful introduction of corrosion protection systems in operating plants.

  • High-Resolution NMR Techniques in Organic Chemistry

    • 2nd Edition
    • Volume 2
    • Timothy D.W. Claridge
    • English
    High-Resolution NMR Techniques in Organic Chemistry describes the most important high-resolution NMR techniques that find use in the structure elucidation of organic molecules and the investigation of their behavior in solution. The techniques are presented and explained using pictorial formats wherever possible, limiting the number of mathematical descriptions. The emphasis is on the more recently developed methods of solution-state NMR spectroscopy with a considerable amount of information on implementation and on the setting of critical parameters for anyone wishing to exploit these methods.

  • Annual Reports in Computational Chemistry

    • 1st Edition
    • Volume 4
    • Ralph A. Wheeler + 1 more
    • English
    Annual Reports in Computational Chemistry is a new periodical providing timely and critical reviews of important topics in computational chemistry as applied to all chemical disciplines. Topics covered include quantum chemistry, molecular mechanics, force fields, chemical education, and applications in academic and industrial settings. Each volume is organized into (thematic) sections with contributions written by experts. Focusing on the most recent literature and advances in the field, each article covers a specific topic of importance to computational chemists. Annual Reports in Computational Chemistry is a "must" for researchers and students wishing to stay up-to-date on current developments in computational chemistry.

  • The Alkaloids

    Chemistry and Biology
    • 1st Edition
    • Volume 66
    • English
    This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than 40 years, The Alkaloids: Chemistry and Biology, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of this rapidly expanding field. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids.

  • Carbohydrates: The Essential Molecules of Life

    • 2nd Edition
    • Robert V. Stick + 1 more
    • English
    This book provides the "nuts and bolts" background for a successful study of carbohydrates - the essential molecules that not only give you energy, but are an integral part of many biological processes.A question often asked is 'Why do carbohydrate chemistry?' The answer is simple: It is fundamental to a study of biology. Carbohydrates are the building blocks of life and enable biological processes to take place.Therefore the book will provide a taste for the subject of glycobiology.Coverin... the basics of carbohydrates and then the chemistry and reactions of carbohydrates this book will enable a chemist to gain essential knowledge that will enable them to move smoothly into the worlds of biochemistry, molecular biology and cell biology.

  • Molecular Characterization and Analysis of Polymers

    • 1st Edition
    • Volume 53
    • John M. Chalmers + 1 more
    • English
    Written by expert contributors from the academic and industrial sectors, this book presents traditional and modern approaches to polymer characterization and analysis. The emphasis is on pragmatics, problem solving and property determination; real-world applications provide a context for key concepts. The characterizations focus on organic polymer and polymer product microstructure and composition.

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 43
    • English
    Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.

  • Aspects of Explosives Detection

    • 1st Edition
    • Maurice Marshall + 1 more
    • English
    Detection and quantification of trace chemicals is a major thrust of analytical chemistry. In recent years much effort has been spent developing detection systems for priority pollutants. Less mature are the detections of substances of interest to law enforcement and security personnel:in particular explosives. This volume will discuss the detection of these, not only setting out the theoretical fundamentals, but also emphasizing the remarkable developments in the last decade. Terrorist events—airplanes blown out of the sky (PanAm 103 over Lockerbie) and attacks on U.S. and European cities (Trade Center in New York and the Murrah Federal Building in Oklahoma City, railways in London and Madrid)--emphasize the danger of concealed explosives. However, since most explosives release little vapor, it was not possible to detect them by technology used on most organic substances. After PanAm 103 was downed over Scotland, the U.S. Congress requested automatic explosive detection equipment be placed in airports. This volume outlines the history of explosive detection research, the developments along the way, present day technologies, and what we think the future holds.

  • Annual Reports on NMR Spectroscopy

    • 1st Edition
    • Volume 64
    • Graham A. Webb
    • English
    The great importance of NMR in many areas of scientific research is once again highlighted in this volume of Annual Reports on NMR Spectroscopy.

  • Advances in Inorganic Chemistry

    • 1st Edition
    • Volume 60
    • Rudi van Eldik
    • English
    The Advances in Inorganic Chemistry series present timely and informative summaries of the current progress in a variety of subject areas within inorganic chemistry, ranging from bio-inorganic to solid state studies. This acclaimed serial features reviews written by experts in the field and serves as an indispensable reference to advanced researchers. Each volume contains an index, and each chapter is fully referenced.

  • Advances in Planar Lipid Bilayers and Liposomes

    • 1st Edition
    • Volume 8
    • A. Leitmannova Liu
    • English
    Advances in Planar Lipid Bilayers and Liposomes, Volume 8, is the latest in our series on both planar lipid bilayers and spherical liposomes. This field of research, based on a historic perspective of the lipid bilayer concept and its experimental realization as well as on spherical liposomes, is growing and developing stronger ties with many new exciting interdisciplinary areas. This volume includes invited chapters on a broad range of topics, covering both main arrangements of the reconstituted system, namely planar lipid bilayers and spherical liposomes. Many of the contributing authors collaborated in the past with the late Prof. H. Ti Tien, the founding editor of this book series. The book also includes chapters written by some of the younger generation of scientists included in this series. This volume keeps in mind the broader goal with both systems, planar lipid bilayers, and spherical liposomes, which is the further development of this interdisciplinary field worldwide. This book is an ideal resource for chemical Engineers, physical chemists, biologists and biochemists, biochemical engineers.

  • Progress in Heterocyclic Chemistry

    • 1st Edition
    • Volume 20
    • Gordon Gribble + 1 more
    • English
    This is the 20th annual volume of Progress in Heterocyclic Chemistry, which covers the literature published during 2007. As with previous volumes in the series, Volume 20 will enable the reader to keep abreast of developments in heterocyclic chemistry in an effortless way.

  • Advances in Chemical Engineering

    Mathematics and Chemical Engineering and Kinetics
    • 1st Edition
    • Volume 34
    • English
    The cross-fertilization of physico-chemical and mathematical ideas has a long historical tradition. This volume of Advances in Chemical Engineering is almost completely dedicated to a conference on “Mathematics in Chemical Kinetics and Engineering” (MaCKiE-2007), which was held in Houston in February 2007, bringing together about 40 mathematicians, chemists, and chemical engineers from 10 countries to discuss the application and development of mathematical tools in their respective fields.

  • Liquid Sample Introduction in ICP Spectrometry

    A Practical Guide
    • 1st Edition
    • José-Luis Todoli + 1 more
    • English
    Inductively coupled plasma atomic or mass spectrometry is one of the most common techniques for elemental analysis. Samples to be analyzed are usually in the form of solutions and need to be introduced into the plasma by means of a sample introduction system, so as to obtain a mist of very fine droplets. Because the sample introduction system can be a limiting factor in the analytical performance, it is crucial to optimize its design and its use. It is the purpose of this book to provide fundamental knowledge along with practical instructions to obtain the best out of the technique.

  • Frontiers of Molecular Spectroscopy

    • 1st Edition
    • Jaan Laane
    • English
    Much of what we know about atoms, molecules, and the nature of matter has been obtained using spectroscopy over the last one hundred years or so. In this book we have collected together twenty chapters by eminent scientists from around the world to describe their work at the cutting edge of molecular spectroscopy. These chapters describe new methodology and applications, instrumental developments, and theory which is taking spectroscopy into new frontiers. The range of topics is broad. Lasers are utilized in much of the research, but their applications range from sub-femtosecond spectroscopy to the study of viruses and also to the investigation of art and archeological artifacts. Three chapters discuss work on biological systems and three others represent laser physics. The recent advances in cavity ringdown spectroscopy (CRDS), surface enhanced Raman spectroscopy (SERS), two-dimensional correlation spectroscopy (2D-COS), and microwave techniques are all covered. Chapters on electronic excited states, molecular dynamics, symmetry applications, and neutron scattering are also included and demonstrate the wide utility of spectroscopic techniques.

  • Protein Mass Spectrometry

    • 1st Edition
    • Volume 52
    • Julian Whitelegge
    • English
    This book is designed to be a central text for young graduate students interested in mass spectrometry as it relates to the study of protein structure and function as well as proteomics. It is a definite must-have work for:- libraries at academic institutions with Master and Graduate programs in biochemistry, molecular biology, structural biology and proteomics- individual laboratories with interests covering these areas - libraries and individual laboratories in the pharmaceutical and biotechnology industries.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 57
    • Anthony F. Hill + 1 more
    • English
    Almost all branches of chemistry and material science now interface with organometallic chemistry--the study of compounds containing carbon-metal bonds. This widely acclaimed serial contains authoritative reviews that address all aspects of organometallic chemistry, a field that has expanded enormously since the publication of Volume 1 in 1964.

  • NMR Spectroscopy in Pharmaceutical Analysis

    • 1st Edition
    • Iwona Wawer + 2 more
    • English
    For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized. Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis. Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples.

  • Capillary Electrophoresis Methods for Pharmaceutical Analysis

    • 1st Edition
    • Volume 9
    • Satinder Ahuja + 1 more
    • English
    Capillary electrophoresis (CE) is a powerful analytical technique that is widely used in research and development and in quality control of pharmaceuticals. Many reports of highly efficient separations and methods have been published over the past 15 years. CE offers several advantages over high-pressure or high-performance liquid chromatography (HPLC). These include simplicity, rapid analysis, automation, ruggedness, different mechanisms for selectivity, and low cost. Moreover, EC requires smaller sample size and yet offers higher efficiency and thus greater resolution power over HPLC. These characteristics are very attractive in research and development, even more so in pharmaceutical quality control (QC) and stability monitoring (SM) studies. This book will provide busy pharmaceutical scientists a complete yet concise reference guide for utilizing the versatility of CE in new drug development and quality control.

  • Inorganic Chemistry

    • 1st Edition
    • James E. House
    • English
    Inorganic Chemistry provides essential information in the major areas of inorganic chemistry. The author emphasizes fundamental principles—including molecular structure, acid-base chemistry, coordination chemistry, ligand field theory, and solid state chemistry — and presents topics in a clear, concise manner. Concise coverage maximizes student understanding and minimizes the inclusion of details students are unlikely to use. The discussion of elements begins with survey chapters focused on the main groups, while later chapters cover the elements in greater detail. Each chapter opens with narrative introductions and includes figures, tables, and end-of-chapter problem sets. This text is ideal for advanced undergraduate and graduate-level students enrolled in the inorganic chemistry course. The text may also be suitable for biochemistry, medicinal chemistry, and other professionals who wish to learn more about this subject are.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 35
    • Atta-ur Rahman
    • English
    This volume presents frontier reviews of recent developments in bioactive natural products in cutting-edge areas by eminent experts in their respective fields. It is an essential addition to this important series on Natural Products Chemistry, generally acknowledged to be the leading series on this topic.

  • The Practice of Medicinal Chemistry

    • 3rd Edition
    • Camille Georges Wermuth
    • English
    The Practice of Medicinal Chemistry fills a gap in the list of available medicinal chemistry literature. It is a single-volume source on the practical aspects of medicinal chemistry. Considered ""the Bible"" by medicinal chemists, the book emphasizes the methods that chemists use to conduct their research and design new drug entities. It serves as a practical handbook about the drug discovery process, from conception of the molecules to drug production. The first part of the book covers the background of the subject matter, which includes the definition and history of medicinal chemistry, the measurement of biological activities, and the main phases of drug activity. The second part of the book presents the road to discovering a new lead compound and creating a working hypothesis. The main parts of the book discuss the optimization of the lead compound in terms of potency, selectivity, and safety. The Practice of Medicinal Chemistry can be considered a ""first-read"" or ""bedside book"" for readers who are embarking on a career in medicinal chemistry.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 96
    • Alan R. Katritzky
    • English
    The definitive serial in the field -- since 1960.

  • Organic Structure Determination Using 2-D NMR Spectroscopy

    A Problem-Based Approach
    • 1st Edition
    • Jeffrey H. Simpson
    • English
    Organic Structure Determination Using 2-D NMR Spectroscopy is a primary text for a course in NMR techniques, with the goal to learn to identify organic molecular structure. It presents strategies for assigning resonances to known structures and for deducing structures of unknown organic molecules based on their NMR spectra.It contains 20 known and 20 unknown structure determination problems and features a supporting website from which instructors can download the structures of the unknowns in selected chapters, digital versions of all figures, and raw data sets for processing. Many other books describe the methods used, but none offer a large number of problems. Instructors at universities and colleges are forced to cobble together problems from a wide range of sources. The fragmentary approach to assembling course materials has a negative impact on course continuity and thus adversely impacts student retention.This book will stand as a single source to which instructors and students can go to obtain a comprehensive compendium of NMR problems of varying difficulty.

  • Evolutionary Essays

    A Thermodynamic Interpretation of the Evolution
    • 1st Edition
    • Sven Erik Jørgensen
    • English
    Evolution is nature’s most fascinating process, the possibility given sufficient time to combine simple inorganic compounds to more and more complex biochemical compounds, which make up more and more complex organisms. It is therefore crucial in our effort to understand the evolution to see it from as many different angles as possible. This books draw an image of evolution from the thermodynamic viewpoint, which gives new and surprising insights into the processes and mechanisms that have driven evolution. This new thermodynamic interpretation has made it possible to quantify the various steps of evolution and to show that evolution has followed an exponential growth curve.

  • Thermophysical Properties of Chemicals and Hydrocarbons

    • 1st Edition
    • Carl L. Yaws
    • English
    Carl Yaws here presents over 7,800 organic and inorganic chemicals, and hydrocarbons. Spanning gases, liquids and solids, and covering all critical properties (including acentric factor, density, enthalpy of vaporization, and surface tension), this volume represents more properties on more chemicals than any single work of its kind, from C1 to C100 organics and Ac to Zr inorganics. Designed and formatted for field, lab or classroom usage, it gives the reader unparalleled access to invaluable data.

  • Computational Modeling of Membrane Bilayers

    • 1st Edition
    • Volume 60
    • V. Sundararajan
    • English
    Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. Each volume is a guest edited compendium of membrane biology.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 34
    • Atta-ur Rahman
    • English
    This volume presents frontier reviews on recent developments on bioactive natural products in cutting-edge areas by eminent experts in their respective fields. Fourteen reviews treat diverse and different topics in natural products chemistry - basic ones, medicinally oriented ones, agro-oriented ones and ecologically oriented ones.It is an important addition to this important series on Natural Products Chemistry, generally acknowledged to be the leading series on this topic.

  • Carbohydrate Chemistry, Biology and Medical Applications

    • 1st Edition
    • Hari G. Garg + 2 more
    • English
    The finding by Emil Fischer that glucose and fructose on treatment with phenylhydrazine gave the identical osazone led him to the elucidation of stereochemistry of carbohydrates. Since then, progress in the field of carbohydrates has been amazing with the unraveling their basic structure, biosynthesis, immunology, functions, and clinical uses, for pure carbohydrates and for protein-linked carbohydrates (glycoproteins and proteoglycans). The chapters in Carbohydrate Chemistry, Biology and Medical Applications present a logical sequence leading from the chemistry and biochemistry of carbohydrates, followed by their role in various pathological conditions, to carbohydrates as potential therapeutic and diagnostic agents. This book offers a detailed panoramic review of the chemistry and biology of carbohydrates for chemists, biologists and health professionals. Each chapter is authored by contributors expert in the particular area of research.

  • Characterization of Semiconductor Heterostructures and Nanostructures

    • 1st Edition
    • Giovanni Agostini + 1 more
    • English
    In the last couple of decades, high-performance electronic and optoelectronic devices based on semiconductor heterostructures have been required to obtain increasingly strict and well-defined performances, needing a detailed control, at the atomic level, of the structural composition of the buried interfaces. This goal has been achieved by an improvement of the epitaxial growth techniques and by the parallel use of increasingly sophisticated characterization techniques and of refined theoretical models based on ab initio approaches. This book deals with description of both characterization techniques and theoretical models needed to understand and predict the structural and electronic properties of semiconductor heterostructures and nanostructures.

  • Advances in Planar Lipid Bilayers and Liposomes

    • 1st Edition
    • Volume 7
    • A. Leitmannova Liu
    • English
    Advances in Planar Lipid Bilayers and Liposomes, Volume 7, continues to include invited chapters on a broad range of topics, covering both main arrangements of the reconstituted system, namely planar lipid bilayers and spherical liposomes. The invited authors present the latest results in this exciting multidisciplinary field of their own research group.Many of the contributors working in both fields over many decades were in close collaboration with the late Prof. H. Ti Tien, the founding editor of this book series. There are also chapters written by some of the younger generation of scientists included in this series. This volume keeps in mind the broader goal with both systems, planar lipid bilayers and spherical liposomes, which is the further development of this interdisciplinary field worldwide.

  • Adsorption by Carbons

    • 1st Edition
    • Eduardo J. Bottani + 1 more
    • English
    Adsorption by Carbons covers the most significant aspects of adsorption by carbons, attempting to fill the existing gap between the fields of adsorption and carbonaceous materials. Both basic and applied aspects are presented. The first section of the book introduces physical adsorption and carbonaceous materials, and is followed by a section concerning the fundamentals of adsorption by carbons. This leads to development of a series of theoretical concepts that serve as an introduction to the following section in which adsorption is mainly envisaged as a tool to characterize the porous texture and surface chemistry of carbons. Particular attention is paid to some novel nanocarbons, and the electrochemistry of adsorption by carbons is also addressed. Finally, several important technological applications of gas and liquid adsorption by carbons in areas such as environmental protection and energy storage constitute the last section of the book.

  • Physical Chemistry

    • 3rd Edition
    • Robert G. Mortimer
    • English
    In this third edition, core applications have been added along with more recent developments in the theories of chemical reaction kinetics and molecular quantum mechanics, as well as in the experimental study of extremely rapid chemical reactions.

  • Advances in Quantum Chemistry

    Applications of Theoretical Methods to Atmospheric Science
    • 1st Edition
    • Volume 55
    • Michael M.E. Goodsite + 3 more
    • English
    Advances in Quantum Chemistry presents surveys of current developments in this rapidly developing field that falls between the historically established areas of mathematics, physics, chemistry, and biology. With invited reviews written by leading international researchers, each presenting new results, it provides a single vehicle for following progress in this interdisciplinary area.Theoretical methods have dramatically extended the reach and grasp of atmospheric scientists. This edition of Advances in Quantum Chemistry collects a broad range of articles that provide reports from the leading edge of this interaction. The chemical systems span the range from atoms to clusters to droplets. Electronic structure calculations are used to uncover the details of the breakdown and removal of emissions from the atmosphere and the simultaneous development of air pollution including ozone and particles. The anomalous enrichment of heavy isotopes in atmospheric ozone is discussed using RRKM theory, and a number of techniques are presented for calculating the effect of isotopic substitution on the absorption spectra of atmospheric molecules.

  • Fluorine and Health

    Molecular Imaging, Biomedical Materials and Pharmaceuticals
    • 1st Edition
    • Alain Tressaud + 1 more
    • English
    Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals. Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and in cardiology for the diagnosis of diseases having the highest mortality in the industrialized countries. The manifold facets of fluorinated biomaterials range from inorganic ceramics to perfluorinated organic molecules. Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms.Medicinall... relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds. The chapters will illustrate how the presence of fluorine atoms alters properties of bioactive compounds at various biochemical steps, and possibly facilitate its emergence as pharmaceuticals. Finally the synthetic potential of a fluorinase, the first C-F bond forming enzyme, is summarized.

  • The Alkaloids

    Chemistry and Biology
    • 1st Edition
    • Volume 65
    • English
    This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than 40 years, The Alkaloids: Chemistry and Biology, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of this rapidly expanding field. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids.

  • Interfacial and Confined Water

    • 1st Edition
    • Ivan Brovchenko + 1 more
    • English
    Water in the proximity of a surface (interfacial water) is abundant on the earth. It is involved in various physical and chemical processes and crucial for biological function. Despite numerous studies of interfacial water, systematic analysis of its properties is missing in scientific literature. This book is a first comprehensive review of experimental and simulation studies of water in various confining environments, such as hydrophilic and hydrophobic surfaces, surfaces of biomolecules, porous media, etc. Systematic analysis of interfacial and confined water is based on the firm physical ground, which accounts for variety of the thermodynamic states of water near the surface, surface phase transitions, surface critical behaviour, effect of confinement on the bulk and surface phase transitions of water, clustering and formation of a spanning hydrogen-bonded water network via percolation transition. This allows distinguishing between universal features, common for all fluids, and some specific water properties, related to intermolecular hydrogen bonds. Special attention is paid to the properties of hydration water, which covers biomolecules and enables their biological activity. This book provides readers with basic information on interfacial and confined water, which will be useful for scientists and engineers working in the fields of bioscienses, nanociences and nanotechnologies.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 46
    • English
    Appropriate selection of biochemical targets is one of the most important drivers of cost effectiveness in the discovery of new medicines. Despite the many advances in genetics, genomics and systems biology, ‘validation’ of a target is not achieved until therapeutic efficacy is demonstrated by a drug candidate. Volume 46 of this series reviews the medicinal chemistry aimed at six diverse targets from which important new medicines are emerging: * HIV integrase (discovery of the first-in-class inhibitor drug raltegravir)* 11-beta-Hydroxystero... dehydrogenase (new approach to glucocorticoid regulation)* Nicotinic a7 choline receptor (agonists and positive allosteric modulators). * Bradykinin receptor (new approach to pain therapy)* Histone deacetylase (new drugs for cancer)* 5-HT2c receptor modulators (various CNS indications)

  • Optical Biosensors

    Today and Tomorrow
    • 2nd Edition
    • Frances S. Ligler + 1 more
    • English
    Optical Biosensors, Second Edition describes the principles of successful systems, examples of applications, and evaluates the advantages and deficiencies of each. It also addresses future developments on two levels: possible improvements in existing systems and emerging technologies that could provide new capabilities in the future. The book is formatted for ease of use and is therefore suitable for scientists and engineers, students and researcher at all levels in the field.

  • Advances in Quantum Chemistry

    DV-Xá for Industrial-Academic Cooperation
    • 1st Edition
    • Volume 54
    • Jun Kawai + 2 more
    • English
    Advances in Quantum Chemistry presents surveys of current developments in this rapidly developing field that falls between the historically established areas of mathematics, physics, chemistry, and biology. With invited reviews written by leading international researchers, each presenting new results, it provides a single vehicle for following progress in this interdisciplinary area. This volume concerns the proceedings of the 4th International Conference on the DV-Xá Method. The focus is on key issues of materials science, surfaces, boundaries, defects, metals, ceramics and organic materials and spectroscopy. The DV-Xá method is a Density Functional-like development, which has reached an unparalleled theoretical and practical sophistication in Japan and Korea.

  • Annual Reports on NMR Spectroscopy

    • 1st Edition
    • Volume 63
    • Graham A. Webb
    • English
    Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has grown to such importance as NMR spectroscopy. It is used in all branches of science when precise structural determination is required and when the nature of interactions and reactions in solution is being studied. Annual Reports on NMR Spectroscopy has established itself as a premier means for the specialist and non-specialist alike to become familiar with new techniques and applications of NMR spectroscopy.

  • Comprehensive Heterocyclic Chemistry III

    A Review of the Literature 1995-2007 1- 15
    • 1st Edition
    • Alan R. Katritzky + 3 more
    • English
    Comprehensive Heterocyclic Chemistry III (CHEC-III) is a new 15-volume reference work which provides the first point of entry to the literature for all scientists interested in heterocyclic ring systems. Since publishing in 1984, Comprehensive Heterocyclic Chemistry (CHEC) has become the standard work on the subject, indispensable to all serious readers in the interdisciplinary areas where heterocycles are employed. CHEC-III builds on and complements the material in CHEC and CHEC-II and is designed to be used both alone and in conjunction with these two works. Written by leading scientists who have evaluated and summarized the most important data published over the last decade, Comprehensive Heterocyclic Chemistry III will be an invaluable addition to the reference library of those working with heterocyclic ring systems.

  • Advances in Organometallic Chemistry

    The Organotransition Metal Chemistry of Poly(pyrazolyl)borates. Part 1
    • 1st Edition
    • Volume 56
    • Robert C. West + 2 more
    • English
    Almost all branches of chemistry and material science now interface with organometallic chemistry - the study of compounds containing carbon-metal bonds. This widely acclaimed serial contains authoritative reviews that address all aspects of organometallic chemistry, a field which has expanded enormously since the publication of Volume 1 in 1964.Volume 56 comprises Part 1 of a themed collection of papers on "The Organotransition Metal Chemistry of Poly(pyrazolyl)borat...

  • State Estimation in Chemometrics

    The Kalman Filter and Beyond
    • 1st Edition
    • Pierre C. Thijssen
    • English
    This unique text blends together state estimation and chemometrics for the application of advanced data-processing techniques. It further applies system theory in order to develop a modular framework to be implemented on computer for the development of simple intelligent analyzers. Short reviews on the history of state estimation and chemometrics are given, together with examples of the applications described, including classical estimation, state estimation, non-linear estimation, the multi-component, calibration and titration systems and the Kalman filter. The contents are very systematic and build the ideas up logically to appeal to specialist post-graduates working in this area, together with professionals in other areas of chemistry and engineering.

  • Drug-like Properties: Concepts, Structure Design and Methods

    from ADME to Toxicity Optimization
    • 1st Edition
    • Li Di + 1 more
    • English
    Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process. The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 95
    • Alan R. Katritzky
    • English
    Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties. Volume 94 of Advances in Heterocyclic Chemistry commences with a review of cascade reactions on heterocyclic synthesis. The chapter presents a fascinating array of complex sequences which provide efficient routes to a wide variety of heterocyclic systems. The second chapter is the twelfth in the series on the organic chemistry of heterocyclic ligands in metallic complexes. The present contribution deals with the chemistry of polypyridine ligands in organomanganese and organorhenium complexes. Its current importance can be measured by the fact that, of the nearly 700 references, approximately half date from the last 10 years. Preparation of aminoisoxazoles and their utility in the synthesis of condensed systems are also covered. In the final chapter, isothiazolium salts and their use in synthesis are reviewed. Many condensed S,N-heterocyclic systems are described in this, the first review dedicated to this topic.

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