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Elsevier

Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

  • Comprehensive Guide to Green Chemistry

    Principles, Materials, and Applications
    • 1st Edition
    • Mohd Amin Mir + 1 more
    • English
    Comprehensive Guide to Green Chemistry: Principles, Materials, and Applications provides an authoritative analysis of green and sustainable chemistry, integrating foundational principles with the advanced materials and technologies that are transforming research and industrial applications. The book provides detailed exploration of green solvents, bio-based polymers, nanomaterials, photocatalysis, and advanced oxidation processes, highlighting their roles in minimizing environmental impact. The text further addresses sustainable synthetic methodologies, pollution control technologies for water, air, and soil, and waste-to-energy strategies within circular economy models, providing a holistic view of resource-efficient chemical practices.It equips professionals and academics with the knowledge and tools necessary to implement environmentally responsible strategies that advance sustainable development objectives. This essential reference supports the transition toward eco-efficient chemistry, enabling the reduction of pollution, conservation of resources, and promotion of long-term ecological balance across diverse sectors.

  • Electroluminescence in Inorganic and Organic Materials

    Fundamentals to Applications
    • 1st Edition
    • Sanjay J. Dhoble + 4 more
    • English
    Electroluminescence in Inorganic and Organic Materials: Fundamentals to Applications provides a comprehensive exploration of electroluminescence, from its fundamental principles to the latest advances in organic and inorganic phosphor materials. Bridging the gap between foundational science and real-world applications, it provides in-depth coverage of materials synthesis, device fabrication, and the optical properties that drive innovation in lighting, displays, and sensing. With a clear focus on the challenges and opportunities in developing next-generation electroluminescent devices, this book equips researchers with the knowledge and tools needed to enhance efficiency, color quality, and application diversity. It provides vital information for optimizing material properties, troubleshooting device performance, and understanding the interplay between structure and function.

  • Green Nanoparticles for Food Safety and Sustainability

    • 1st Edition
    • Volume 102
    • English

  • Rapid Sensors for Wastewater-Based Epidemiology

    • 1st Edition
    • Volume 107
    • English
    Rapid sensors for waterwaste based epidemiology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Physical Chemistry at the Intersection of Combustion and Atmospheric Sciences

    • 1st Edition
    • Brandon Rotavera
    • English
    Physical Chemistry at the Intersection of Combustion and Atmospheric Sciences provides the first detailed exploration of overlapping scientific problems in physical chemistry within the domains of combustion and atmospheric chemistry. Specific problems addressed in this book include detailing the current state of knowledge and future research needs on topics, such as the role of organic hydroperoxide reactivity in both atmospheric chemistry and combustion, the importance of peroxy radicals produced in biofuel and hydrocarbon combustion that control chain-branching, and in tropospheric chemistry, affect OH-budgeting and the formation of aerosols that impact air quality.Significant attention is also paid to the influence of functional groups on combustion reaction mechanisms as well as downstream effects on gas-phase chemical reactions in atmosphere. Specifically, problems connecting gas-phase reactions of functionalized organic molecules present in combustion emissions to secondary organic aerosol (SOA) formation are addressed. In addition, remaining challenges in understanding the subsequent physical and chemical processes involving SOA will be addressed. It is written primarily for research staff scientists, R&D personnel (laboratory and industry), graduate students, and professors in the fields of physical chemistry, atmospheric science, and chemical engineering.

  • Mechanical Processes in Solid-Phase Transformations

    The Role of Stresses and Relaxation Processes in the Kinetics of Polymorphic Transformations and Chemical Reactions
    • 1st Edition
    • Stanislav A. Chizhik + 2 more
    • English
    Mechanical Processes in Solid-Phase Transformations: The Role of Stresses and Relaxation Processes in the Kinetics of Polymorphic Transformations and Chemical Reactions provides a systematic treatment of the role of mechanical feedback through several different real-world examples covering the major types of solid-state transformations. It provides a novel, comprehensive and in-depth analysis of the role of mechanical stresses and relaxation processes induced by solid-state chemical reactions. This topic has previously been addressed in a very fragmented manner, with a primary focus on superficial phenomenological levels and qualitative conclusions.The chapters feature experimental results and quantitative models of the kinetics of various types of solid-state transformations (polymorphic phase transitions, topochemical reactions, photochemical reactions in crystals) accompanied by stress, plastic deformation, fracture, and macroscopic changes in the shape of crystals. Clear examples are given of controlling transformation kinetics and product morphology by influencing mechanical properties and conditions. Mechanical Processes in Solid-Phase Transformations will help to improve understanding in the growing field of solid-state mechanochemical transformations and polymorph control.It is written for academics both in research and advanced graduate/postdoc level teaching, as well as their students, who are interested in solid-state chemistry, materials science, solid-state physics, or applications of solid-state reactivity to industry. It will also be relevant to this in the areas of nanotechnology, chemical engineering, catalysis and also pharmaceutical technologies.

  • Introduction to the Mechanochemistry of Solids

    • 1st Edition
    • Adam A.L. Michalchuk + 2 more
    • English
    Introduction to the Mechanochemistry of Solids offers a thorough exploration of mechanochemistry, a field rapidly reshaping modern chemistry by enabling solvent-free, efficient synthesis of materials. The book serves as a vital resource for those new to solid-state reactivity, presenting foundational theories and practical insights that illuminate how mechanical forces can drive chemical change. Readers are introduced to the complexities of mechanochemical processes, the nuances of device selection, and the impact of sample preparation, providing a solid framework for understanding how physical forces influence chemical transformations in solids.In addition, the book discusses the growing diversity of scientists contributing to mechanochemistry and outlines the transformative potential of this technology for sustainable and green chemistry. It is especially recommended for advanced undergraduate and graduate students as well as researchers in chemistry, materials science, and related fields.

  • Introduction to Monte Carlo Simulation Methods for Chemistry and Physics

    Fundamentals, Advanced Techniques, and Practical Applications
    • 1st Edition
    • Alberto Gustavo Albesa + 1 more
    • English
    Introduction to Monte Carlo Simulation Methods for Chemistry and Physics explains how stochastic sampling connects molecular models with observable properties. It develops the physical and mathematical ideas behind Monte Carlo methods and shows how they guide the implementation and interpretation of simulations.The treatment progresses from basic sampling to reactive, kinetic, nonequilibrium, and quantum Monte Carlo methods. Applications to chemical equilibrium, adsorption, surface processes, and phase behaviour show how these approaches address problems in chemistry, physics, and materials science. Computational examples connect the governing equations with algorithms and the physical interpretation of results.Written for senior undergraduate and graduate students in chemistry and physics, the book also supports researchers in chemical engineering and materials science who need a clear introduction to molecular simulation.

  • Nanostructured Carbon and Composites

    Design Fundamentals and Supercapacitor Applications
    • 1st Edition
    • Zesheng Li + 2 more
    • English
    Nanostructured Carbon and Composites: Design Fundamentals and Supercapacitor Applications provides an accessible yet in-depth analysis of nanostructured carbon materials, including their synthesis, structure-property relationships, and applications in supercapacitors. By incorporating case studies and practical applications, such as the application of 3D graphene and defective carbon materials, the book bridges the gap between theory and real-world applications, providing tangible insights into the design and implementation of advanced supercapacitor systems and appealing to both academics and industry professionals. Strategies for optimizing pore structures, dimensionality, atomic functionalization, and device configurations are outlined in detail, directly addressing the need for performance enhancement in supercapacitors. The book emphasizes underexplored aspects such as the nanometer effect and atomic structure regulation, offering novel insights not commonly found in existing literature. The inclusion of methodologies for in situ characterization and computational modeling equips readers with tools to tackle challenges in material and device development. The book aligns with trends in renewable energy integration, flexible electronics, and wearable devices, ensuring its applicability to current and future technological advancements.

  • Nuclear Chemistry

    Nuclear Science and the Structure of the Atomic Nucleus
    • 1st Edition
    • Heather L. Crawford
    • English
    Nuclear chemistry is an active research area aimed at understanding the structure of the atomic nucleus, but also in understanding how this structure impacts other aspects of the world around us, including the limits of existence in terms of the heaviest elements, the equation of state for nuclear matter and the use of exotic nuclei for societal applications. Nuclear Chemistry: Nuclear Science and the Structure of the Atomic Nucleus addresses the current state of the art in nuclear science, with a focus on sub-topics which remain strongly tied to chemistry rather than to physics disciplines. Nuclear science is historically nuclear chemistry; connections between nuclear science and chemical science are deep, substantial but often underappreciated. This volume will provide the necessary background, both scientific and historic, for students and experienced researchers alike to understand and appreciate the science of the atomic nucleus and the cutting-edge research which is ongoing in this area. The book is intended to provide a first introduction and overview of nuclear chemistry and nuclear science with chapters outlining the basic concepts before sections dealing with a range of core topics and highlighting current research directions to provide a reader with a clear overall sense of the field. This book is an ideal primer for advanced undergraduate and graduate-level students, postdoctoral researchers and research scientists in the fields of nuclear science, physical chemistry, chemical physics, particle physics and atomic theory. It will also be of interest to biochemists, medical personnel, material scientists, cosmochemists, radiochemists and others engaged in isotopes research, who may utilize nuclear techniques in their work.

  • Introduction to Computational Electrochemistry

    Modelling Methods and Applications in Interfacial Phenomena, Electrocatalysis, and Energy Storage
    • 1st Edition
    • Hyungjun Kim + 2 more
    • English
    Introduction to Computational Electrochemistry: Modelling Methods and Applications in Interfacial Phenomena, Electrocatalysis, and Energy Storage addresses the various methodologies and intricate processes involved in electrochemical energy interconversion. Recent advancements in incorporating both the electronic responses of electrodes and the molecular dynamic responses of electrolytes are highlighted, thus enabling a deeper understanding of the physicochemical processes occurring at electrode-electrolyt... interfaces. The book also introduces applications of modern computational chemistry to various electrochemical systems, including electrocatalytic systems for efficient energy conversion and energy storage systems such as batteries and supercapacitors. Emphasis is placed on state-of-the-art multiscale approaches for the advanced simulation of electrochemical interfaces.By presenting case studies that illustrate underlying mechanisms, explaining experimental observations, and guiding the design of improved systems, the book shows how computational electrochemistry increasingly interplays with experiments in the field of electrochemistry. This book aims to help pave the way for near-future developments that will unravel the atomic details of electrochemical interfaces and foster the growth of non-conventional methodological approaches.

  • Frontiers in Green Chemistry

    Sustainable Materials and Environmental Applications
    • 1st Edition
    • Mohd Amin Mir + 1 more
    • English
    Frontiers in Green Chemistry: Sustainable Materials and Environmental Applications offers a thorough guide to how green chemistry can drive environmental sustainability and address pressing global challenges. Integrating core principles with innovative technologies, it explores renewable energy, eco-friendly practices, and solutions like biofuels, green hydrogen, and solar-driven chemical processes.What sets this book apart is its strong focus on real-world applications. It shows how green chemistry affects everyday life, from agriculture and food packaging to community initiatives. Case studies, emerging trends, and practical examples showcase successful innovations, making sustainability tangible and actionable.Ideal for graduate students, researchers, industry professionals, and policymakers, this volume advances both understanding and practice in green chemistry. It provides guidance for developing environmentally responsible technologies, improving efficiency, and shaping sustainability-orien... policies, illustrating how sustainable practices can be integrated across science, industry, and communities.

  • Breathborne Biomarkers and the Human Volatilome

    From Chemistry and Biology to Technology and Applications
    • 3rd Edition
    • Jonathan Beauchamp + 1 more
    • English
    Breathborne Biomarkers and the Human Volatilome: From Chemistry and Biology to Technology and Applications, Third Edition, is the definitive resource for researchers, clinicians, and industry professionals interested in the power of breath analysis for health and disease monitoring. This comprehensive guide covers the latest scientific discoveries, innovative detection technologies, and practical applications of volatile organic compounds (VOCs) in breath, offering valuable insights into how these biomarkers can be used for early diagnosis, personalized medicine, and environmental exposure assessment. Whether you are developing new diagnostic tools or conducting advanced research, this book provides the essential knowledge needed to unlock the full potential of breath analysis. With in-depth coverage of biomarkers, data analytics, and cutting-edge sensor technologies, this edition bridges fundamental science with real-world applications. It is an ideal reference for scientists, healthcare professionals, and industry innovators aiming to stay at the forefront of this rapidly evolving field. By providing clear explanations, current perspectives, and future directions, Breathborne Biomarkers and the Human Volatilome: From Chemistry and Biology to Technology and Applications, Third Edition empowers readers to harness the power of breath for improved health outcomes and environmental monitoring—making it an indispensable tool in modern biomedical science.

  • Negative-Ion Chemical Ionization in Mass Spectrometry

    Basic Principles and Interpretation of Spectra
    • 1st Edition
    • Dimitrios Tsikas
    • English
    Gas Chromatography-Mass Spectrometry (GC-MS)-based technologies are widely utilized for the qualitative and quantitative analysis of derivatives of organic analytes. Mass spectra are the identity cards of organic molecules. Understanding and interpreting mass spectra are of key importance in various fields of chemistry and related disciplines. The negative-ion chemical ionization (NICI) technique is now extensively used and has been developed almost two decades after electron ionization (EI) and there is a lack of introductory resource enabling the effective harnessing of this important research technique.Negative-I... Chemical Ionization in Mass Spectrometry: Basic Principles and Interpretation of Spectra deals in-depth with the interpretation of NICI mass spectra specifically. Reported NICI mass spectra of different classes of unlabelled and stable-isotope labelled organic analytes, the isotopologs, serve as examples for a detailed step-by-step interpretation and final structural elucidation of the analytes. The book provides deep insights into the basic mechanisms that occur in gas chromatography, which include H/D isotope effects, kinetic H/D effects, cis/trans effects, and isomerism, and mass spectrometry, namely chemical ionization by secondary electrons, reduction, oxidation, fragmentation and rearrangement reactions in the gas phase, collision-induced dissociation (CID). Nitrogen rules in GC-NICI-MS and GC-NICI-MS/MS are presented in examples and applied to NICI mass spectra. Solid knowledge of the mechanisms in GC-NICI-MS and GC-NICI-MS/MS are also shown to be key for a deeper understanding of gas-phase reactions and for successful quantitative analytical chemistry in the life sciences.Negative-Io... Chemical Ionization in Mass Spectrometry is written for advanced undergraduate and postgraduate students, researchers and their tutors primarily in analytical chemistry and organic chemistry. The book is also addressed to researchers from surrounding life sciences disciplines such as medicinal and pharmaceutical chemistry, biochemistry, pharmacology, toxicology, and the environmental and climate sciences.

  • Multiscale Simulation Methods for CO2 Capture, Storage, and Utilisation

    From Molecular Insights to Scalable Solutions in Carbon Management
    • 1st Edition
    • Devis Di Tommaso + 1 more
    • English
    As the urgency to address climate change grows, innovative solutions to reduce atmospheric CO2 are becoming essential. Multiscale Simulation Methods for CO2 Capture, Storage, and Utilisation: From Molecular Insights to Scalable Solutions in Carbon Management introduces advanced simulation methods for modelling the processes controlling CO2 capture, storage, and utilisation (CCSU), from the nano to the macro perspective. Whilst the current literature primarily focuses on the engineering aspects of CCSU, there is a notable lack of helpful learning-focused information on how CO2 conversion and utilization processes can be modelled, understood, quantified, and improved in an effective manner using a molecular-level approach. This book is designed to equip readers with the knowledge and tools to develop and optimize these solutions through advanced modelling techniques. It integrates the latest research and methodologies from traditional physics-based computational chemistry methods, machine learning techniques, and macroscale engineering approaches. It is particularly valuable for computational chemists who are primarily interested in modelling chemical reactions for CO2 conversion but have limited exposure to the engineering aspects and economic costs of these processes. Integrating the latest research and methodologies across multiple disciplines including computational chemistry, materials science, and chemical engineering, Multiscale Simulation Methods for CO2 Capture, Storage, and Utilisation: From Molecular Insights to Scalable Solutions in Carbon Management provides a valuable resource for guiding both academic research and practical applications.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 152
    • English
    Advances in Heterocyclic Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Progress in Heterocyclic Chemistry

    • 1st Edition
    • Volume 38
    • R. Alan Aitken + 1 more
    • English
    Progress in Heterocyclic Chemistry (PHC), Volume 38, is the latest in this annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year’s literature on heterocyclic chemistry and articles on new developing topics of particular interest to heterocyclic chemists. The highlight chapters in Volume 38 are all written by leading researchers in their field and these chapters constitute a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2026. As with previous volumes in the series, Volume 38 will enable academic and industrial chemists, and advanced students, to keep abreast of developments in heterocyclic chemistry in a convenient way.

  • Analytical Chemistry for Nonaqueous Solutions

    • 1st Edition
    • Mazaher Ahmadi + 2 more
    • English
    Analytical Chemistry for Nonaqueous Solutions is an authoritative volume that addresses a critical gap in the literature by thoroughly exploring both theoretical underpinnings and current, emergent applications of nonaqueous systems. Combining fundamental principles with advanced methodologies, the book covers a broad spectrum of techniques, including titrimetric, electrochemical, spectroscopic, chromatographic, and mass spectrometric methods, applied to nonaqueous solvents. The book highlights emerging trends such as ionic liquids, green analytical chemistry, and computational modelling, providing insights into solvent properties, classification, and their practical applications across industries such as pharmaceuticals, environmental monitoring, petrochemicals, and forensic science. By integrating case studies, troubleshooting strategies, and detailed procedural guidance, it facilitates effective method development, optimization, and data interpretation in complex nonaqueous environments. Designed for graduate students, researchers, and R&D professionals, this volume serves as both a learning resource and a practical guide. It equips analytical chemists, method developers, and industry practitioners to select appropriate solvents, understand solvent–solute interactions, and troubleshoot techniques originally designed for aqueous systems. The structured approach, including visual abstracts, practice exercises, and extensive appendices, ensures users can effectively apply principles in research and industry settings. As a forward-looking reference, the book supports ongoing innovation and sustainability efforts in the evolving field of nonaqueous analytical chemistry, making it an essential resource for advancing both knowledge and practice.is an authoritative volume that addresses a critical gap in the literature by exploring both theoretical underpinnings and emergent applications of nonaqueous systems. Combining fundamental principles with advanced methodologies, the book covers a range of techniques, including titrimetric, electrochemical, spectroscopic, chromatographic, and mass spectrometric methods. The book highlights emerging trends such as ionic liquids, green analytical chemistry, and computational modelling, providing insights into solvent properties, classification, and practical applications across industries such as pharmaceuticals, environmental monitoring, petrochemicals, and forensic science. By integrating case studies, troubleshooting strategies, and procedural guidance, it facilitates method development, optimization, and data interpretation in complex nonaqueous environments. Designed for graduate students, researchers, and R&D professionals, this volume serves as both a learning resource and a practical guide. It equips analytical chemists, method developers, and industry practitioners to select appropriate solvents, understand solvent–solute interactions, and troubleshoot techniques originally designed for aqueous systems. The structured approach, including visual abstracts, practice exercises, and extensive appendices, ensures users can effectively apply principles in research and industry settings. As a forward-looking reference, the book supports ongoing innovation and sustainability efforts in the evolving field of nonaqueous analytical chemistry, making it an essential resource for advancing both knowledge and practice.

  • Metamorphosis of Computational Chemistry Driven by Artificial Intelligence and Industry 5.0

    • 1st Edition
    • Garikapati Narahari Sastry + 3 more
    • English
    Metamorphosis of Computational Chemistry Driven by Artificial Intelligence and Industry 5.0 explores the cutting-edge synergy among Computational Chemistry, Artificial Intelligence (AI), and the emerging paradigm of Industry 5.0. The book offers a comprehensive, introductory overview of how AI-driven techniques are revolutionizing the field of computational chemistry and transforming industries. Readers will explore the convergence of AI algorithms, big data analytics, and advanced computational methods such as Natural language Processing, Image Processing, and Machine Learning in the context of chemical research and industrial processes. The book also discusses how AI is accelerating Computational Chemistry, Materials Science, and Chemical Engineering by automating complex calculations, predicting molecular properties, and optimizing chemical processes. Furthermore, it provides a deep dive into the concept of Industry 5.0, which envisions a new era of manufacturing characterized by human-robot collaboration, intelligent factories, and decentralized production systems. The book illustrates how AI and Computational Chemistry play pivotal roles in realizing the vision of Industry 5.0 by optimizing manufacturing processes, quality control, and sustainability efforts.

  • Smart Chemical Sensors

    AI and IoT for Global Sustainability
    • 1st Edition
    • Samuel Mugo
    • English
    Smart Chemical Sensors: Integrating AI and IoT for Real-World Applications examines the transformative potential of chemical sensors, highlighting their role in advancing technologies that enhance global sustainability and improve living standards for communities across both the Global North and South. With a focus on AI-powered chemical sensors and IoT integration, the book empowers its audience with a one-stop resource that highlights the most current research on these technologies and how they can be deployed to tackle global challenges in environmental monitoring, healthcare, industrial safety, and agriculture. From smart water quality monitoring and air pollution control to precision agriculture and personalized affordable healthcare, the book demonstrates how interdisciplinary approaches combining biochemical sensors, IoT, and AI are driving impactful solutions that can democratize societal well-being. It also addresses important ethical, governance, and policy considerations to ensure that these technologies benefit all communities, especially those in the Global South. Featuring detailed case studies in industrial automation, precision agriculture, and digital health, the book supports specialized coursework and interdisciplinary research across sustainable development, AI, and smart technologies, making it a valuable resource at all educational levels. Ultimately, this book serves as a comprehensive guide for students, researchers, industry experts, and policymakers eager to understand and contribute to the global movement toward a more sustainable and equitable future by leveraging AI-powered chemical sensors and data analytics.

  • Medicinal Plants of Asia Volume 2

    Novel Sources for Drug Discovery
    • 1st Edition
    • Muhammad Asif Hanif + 5 more
    • English
    Medicinal Plants of South Asia: Novel Sources for Drug Discovery Volume 2 offers a comprehensive exploration of the extraction, isolation, identification, and bioactivity of key natural products used in traditional medicine. This book uniquely synthesizes traditional knowledge from with contemporary scientific research, detailing the medicinal chemistry, pharmacology, and toxicology of over 20 significant plants. Each chapter follows a template that easily allows for cross-referencing information between chapters and plants, in keeping with the template from Volume 1. Targeted at graduate students, researchers, and professionals in pharmacology, ethnobotany, and natural product chemistry, this book serves as an essential resource for those seeking to deepen their understanding of South Asian medicinal plants. By addressing the gap between traditional practices and modern scientific validation, it empowers readers to explore new avenues for research and application in the field.

  • Computational Modeling for Advanced Photovoltaics

    Materials, Interfaces, and Phenomena for Beyond-Silicon Solar Cells
    • 1st Edition
    • Sergei Manzhos + 3 more
    • English
    The need to develop innovative solar cell technologies beyond traditional silicon is becoming ever more central to efficient and scalable solar-to-electrical energy conversion. Computational Modeling for Advanced Photovoltaics: Materials, Interfaces, and Phenomena for Beyond-Silicon Solar Cells provides a structured approach to understanding key post-silicon solar cell technologies, including Perovskite Solar Cells (PSC), Organic Solar Cells (OSS), Dye-Sensitized Solar Cells (DSSC), and tandem cells. It outlines the computational challenges and opportunities associated with each technology, providing insights into the modeling techniques best suited for analyzing light absorption, electron transport, and material properties. The chapters feature clear explanations of various modeling methods, from Density Functional Theory (DFT) to emerging techniques like time-dependent DFTB and orbital-free DFT, which promise enhanced accuracy in solar cell applications. The book also highlights the role of data-based methods and materials informatics, bridging the gap between computational chemistry and practical solar cell research. The volume emphasizes didactic value, ensuring that readers can navigate the complexities of computational modeling with ease. It provides a comprehensive guide to the fundamental computational methodologies driving advancements in what is a hugely dynamic field. Modelling of Materials and Processes for Post-Silicon Photovoltaics is written primarily for graduate students and researchers at the intersection of solar energy technologies and computational materials chemistry and science, as well as being accessible to undergraduate students in advanced courses related to these fields. It will be invaluable for computational chemists and faculty seeking to expand their knowledge of modeling techniques in photovoltaics.

  • Robust Theoretical Models in Medicinal Chemistry

    QSAR, Artificial Intelligence, Machine Learning, and Deep Learning
    • 1st Edition
    • Luciana Scotti + 1 more
    • English
    Robust Theoretical Models in Medicinal Chemistry: QSAR, Artificial Intelligence, Machine Learning, and Deep Learning serves as a valuable resource chock full of applications extending into multiple knowledge domains. The meticulous construction of a robust model holds significance, not only in drug discovery but also in engineering, chemistry, pharmaceutical, and food-related research, illustrating the broad spectrum of fields where QSAR methodologies can be instrumental. The activities considered in QSAR span chemical measurements and biological assays, making this approach a versatile tool applicable across various scientific domains. Currently, QSAR finds extensive use in diverse disciplines, prominently in drug design and environmental risk assessment.Quantitat... Structure-Activity Relationships (QSAR) represent a concerted effort to establish correlations between structural or property descriptors of compounds and their respective activities. These physicochemical descriptors encompass a wide array of parameters, accounting for hydrophobicity, topology, electronic properties, and steric effects, and can be determined empirically or, more recently, through advanced computational methods.

  • Cosmetic Science and Technology

    Theoretical Principles and Applications
    • 2nd Edition
    • Kazutami Sakamoto + 4 more
    • English
    Cosmetic Science and Technology: Theoretical Principles and Applications, Second Edition covers the fundamental aspects of cosmetic science that are necessary to understand material development, formulation, and the dermatological effects that result from the use of these products.The book fulfils this role by offering a comprehensive view of cosmetic science and technology, including environmental and dermatological concerns. As the cosmetics field quickly applies cutting-edge research to high value commercial products that have a large impact in our lives and on the world's economy, this book is an indispensable source of information that is ideal for experienced researchers and scientists, as well as non-scientists who want to learn more about this topic on an introductory level.The second edition features much greater emphasis on the sustainable development goals which have now become so central to the cosmetics industry and society more generally, linked to critical environmental and safety concerns which are also increasingly central to the field. This book will appeal to chemical engineers, chemists, physical chemists and cosmetic chemists in cosmetics research and development, as well as dermatologists and toxicologists.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 137
    • English
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • The Alkaloids

    • 1st Edition
    • Volume 97
    • English
    The Alkaloids, Volume 97 continues the longstanding tradition of this authoritative series, presenting in-depth and up-to-date reviews on the chemistry and biology of alkaloids. This volume features comprehensive chapters on the chemistry and biology of phthalide alkaloids, the structure, biological activity, and chemical synthesis of Myrioneuron alkaloids, and the chemistry of quinoline alkaloids. Together, these contributions provide critical insights into alkaloid structures, biosynthetic origins, biological activities, and synthetic strategies. This volume serves as an essential reference for researchers and advanced students working in natural products chemistry, medicinal chemistry, chemical biology, and pharmacognosy.

  • Organometallic Chemistry of Pyrazoles and Pyrazol-1-yl Chelates

    • 1st Edition
    • Alexander Sadimenko
    • English
    Organometallic Chemistry of Pyrazoles and Pyrazol-1-yl Chelates offers in-depth information on the synthesis, coordination modes, and reactivity of pyrazoles and pyrazol-1-yl chelating compounds, as well as their organometallic complexes and various derivatives including chelating ligands, oligomers, and macrocycles. The significance of these compounds in modern materials chemistry, encompassing optical materials, catalysts, fuels, and other applications, is carefully highlighted. With diverse material sourced from approximately 3000 references, this publication aims to provide a unified and comprehensive database, ensuring its relevance until significant shifts in research trends necessitate a new edition.The book facilitates easy and prompt access to information sources related to the discussed topics. It provides access to modern synthetic methods, potential coordination situations, reactivity trends of coordinated heteroaromatic ligands, and approaches for constructing advanced materials. By utilizing this book in conjunction with the accompanying database, researchers can effectively evaluate the year-to-year trends in the development of organometallic chemistry in heterocycles.

  • Natural Deep Eutectic Solvents

    From Fundamentals to Environmental, Food, and Pharmaceutical Applications
    • 1st Edition
    • Pallavi Jain + 4 more
    • English
    Natural Deep Eutectic Solvents: From Fundamentals to Environmental, Food, and Pharmaceutical Applications offers an in-depth exploration of NADES, covering both their core principles and practical uses. The book aims to bridge scientific research with industrial practices, emphasizing the role of NADES in promoting environmentally sound and efficient solutions. It begins with a clear introduction to the basics of NADES, including classification, design, and characterization, along with an assessment of their environmental impact. Structured into six sections, the book discusses key topics such as environmental applications (pollutant removal, heavy metal removal, oil and gas recovery, etc), food-related uses (antifreezing, phenolic extraction, preservation, eco-friendly agriculture, etc), pharmaceuticals and biotechnology (green solvents, drug delivery, biotechnological tools, etc), and extraction techniques (HPLC, microextraction, bioactive compound recovery, etc). The final section considers future directions, focusing on sustainability, energy recovery, and recent innovations. Each chapter is concise, well-illustrated, and designed for practical understanding, making it a valuable resource for both students and researchers. Targeted at postgraduates, PhD scholars, researchers, practitioners, and industry professionals, this book supports the development and application of sustainable technologies through green chemistry principles. It aims to inspire further research and facilitate the practical implementation of NADES across scientific and industrial sectors, contributing to a greener, more sustainable future.

  • Visual Guide to Natural Product Synthesis

    Marine Natural Products, Volume 3
    • 1st Edition
    • Abdul Hameed + 3 more
    • English
    Marine natural products represent one of the most chemically diverse and biologically promising classes of compounds known to science. Visual Guides to Natural Product Synthesis: Marine Natural Products (Vol‑3) offers a clear and accessible roadmap to their synthesis, presenting complex strategies in a schematic, easy‑to‑follow format. By focusing on distinct structural scaffolds and highlighting the most significant compounds in each category, this volume provides researchers and students with a quick yet comprehensive understanding of key synthetic pathways. Designed for chemists, biologists, and environmental scientists alike, this book bridges disciplines by combining cutting‑edge synthetic methodologies with sustainability considerations and global perspectives. It serves as an invaluable resource for academic researchers seeking the latest advances, industry professionals exploring new biologically active agents, and educators looking for structured teaching material. With its emphasis on clarity, inclusiveness, and real‑world application, this volume is set to become a definitive reference in the field of marine natural product synthesis.

  • Medicinal and Aromatic Plants

    Trends, Technological Innovations and Sustainability
    • 1st Edition
    • Sanjeet Mehariya + 2 more
    • English
    Medicinal and Aromatic Plants: Trends, Technological Innovations and Sustainability explores the latest advancements and sustainable practices in the cultivation, extraction, and application of medicinal and aromatic plants (MAPs). Focusing on enhancing the value and bioactive compound content of MAPs, this book integrates cutting-edge technologies and green methodologies to support industrial, health, and environmental applications. The book is structured into three comprehensive parts; Part I addresses cultivation strategies aimed at improving metabolite content, including artificial intelligence approaches, plant tissue culture technologies, and abiotic stress techniques. Part II investigates advanced extraction, purification, and analytical methods for recovering and identifying high-value biologically active compounds. Part III highlights diverse applications such as functional foods, cosmetics, biopesticides, and the utilization of residual biomass for soil health and value addition. The book also discusses market trends and conservation challenges, providing insights into sustainable development within the MAP sector. This book serves as an essential resource for researchers, industry professionals, agronomists, and researchers engaged in medicinal and aromatic plant sciences, offering practical knowledge and innovative solutions to advance sustainability in the field.

  • Pattern Recognition Techniques in Gas Sensing

    • 1st Edition
    • Ajit Khosla + 2 more
    • English
    Pattern Recognition Techniques in Gas Sensing overviews the methods and technologies used to detect and analyze gases through advanced pattern recognition approaches. The book begins by introducing the fundamentals of gas sensors and their unique data characteristics, laying the groundwork for understanding the complexities involved in gas detection. It then explores the basics of pattern recognition, detailing various statistical methods that have been traditionally employed to interpret sensor data. The text looks into Bayesian and probabilistic methods, offering insights into their applications for improving gas sensing accuracy.Cluster analysis techniques are examined as tools for grouping sensor responses to identify specific gas patterns. The integration of machine learning in gas sensing is thoroughly discussed, highlighting how these algorithms enhance detection capabilities by learning from complex datasets. Further, the book presents deep learning techniques, showcasing their power in handling large volumes of sensor data and extracting meaningful features for precise gas identification. Data processing techniques essential for preparing and refining sensor outputs are also covered, providing readers with practical knowledge for real-world applications and future directions.

  • Understanding Molecular Processes using Electrochemical Methods

    • 1st Edition
    • Ashis Kumar Satpati + 1 more
    • English
    Understanding Molecular Processes using Electrochemical Methods offers a detailed compendium of techniques for molecular analysis. The book considers step and sweep techniques, scanning electrochemical microscopy, spectroelectrochemic... techniques, electrochemiluminesc... and scanning probe techniques while also exploring COSMOL multiphysics simulation, electroanalysis in biomedical and clinical applications, and future prospects for electrochemical techniques. Chapters focus on evaluating redox reactions, biological interactions, kinetics, quorum sensing, biofilm formation, surface modification and more molecular aspects. This volume offers a deep-dive into the fundamental principles behind the latest electrochemical techniques, equipping researchers with practical guidance for their own experiments.Users will find this to be an ideal reference for researchers working across a range of disciplines including molecular biology, bioanalytical chemistry, biomedical science, and translational medicine.

  • Emerging White Analytical Chemical Methods: Design of Approaches and Utilizations Beyond Green

    • 1st Edition
    • Volume 117
    • English
    The book Emerging White Analytical Methods gives an overview of the development, principles and progress, as well as the future of a new paradigm in analytical chemistry: White Analytical Chemistry (WAC) which combines analytical performance with the principles of sustainability, green chemistry and efficient resource use. The book covers the evolution of analytical methodology from the past to the present, with a specific focus on the evolution of analytically efficient, cost-effective and environmentally friendly analytical systems. It spans the full range of advanced analytical technologies including sample preparation methods that are environmentally friendly; chromatographic and electrophoretic methods; membrane-based methods; spectroscopic methods; microfluidics; lab on a chip technology; miniaturized instruments and intelligent analytical systems. Applicability of WAC in pharmaceuticals, clinical and biomedical sciences, food and agriculture and forensic investigations is highlighted. In addition, the volume showcases the transformative power of chemometrics, machine learning, artificial intelligence, bioengineered green nanomaterials, and open-access hardware/software platforms in paving the way for the future of analytical methods. It also covers several important issues including toxicity assessment, safety issues, regulatory issues, and legal issues concerning new generation Green Nanomaterials. The book brings together fundamental concepts, technological developments, applications and future directions and will therefore be useful for researchers, academicians, industry professionals and students in the field of analytical chemistry, green chemistry, nanotechnology, biotechnology and related interdisciplinary areas.

  • Elementary Kinetic Modelling in Catalytic Reaction Engineering

    • 1st Edition
    • Joris W. Thybaut + 5 more
    • English
    Elementary Kinetic Modelling in Catalytic Reaction Engineering is a practical focused text that brings together the relevant basics for reaction engineering and shows their applications to a wide variety of examples, whilst looking at the intrinsic kinetics data acquisition, reaction mechanism elucidation, elementary step-based modelling and model-based design and optimization involved.The book aims at spanning the entire process from acquisition of the relevant data in specifically designed experimental set-ups, over the proper data treatment and the corresponding interpretation up to the quantification of the gained understanding in a (kinetic) model. The latter aspect allows the reader to challenge the interpretation made of the data and design subsequent experiments or improve the interpretation/model formulation. The coverage goes beyond the generic (theoretical) principles, which are, evidently, also dealt with, by carefully considering and explaining their application to a variety of real-life applications including gas- and liquid-phase reactions, heterogeneously catalyzed reactions involving adsorption either in the Henry regime or at full saturation of the catalyst or combined homogeneous-heteroge... reactions.Elementary Kinetic Modelling in Catalytic Reaction Engineering is written primarily for graduate students and postdoc researchers in chemical engineering or applied industrial chemistry studying chemical reaction engineering and catalysis, as well as physical chemists studying kinetics.

  • Comprehensive Analytical Chemistry

    • 1st Edition
    • Volume 117
    • English

  • Introduction to Practical EPR Spectroscopy

    • 1st Edition
    • Wilfred R. Hagen
    • English
    Introduction to Practical Electron Paramagnetic Resonance (EPR) Spectroscopy of randomly oriented molecules finds wide application in chemistry, biology, and many other related disciplines. This graduate-level text guides the reader along the winding road of the undocumented pitfalls and unwritten rules-of-thumb that come with undertaking practical EPR spectroscopy. The aim is to provide a truly practical and complete introduction to this widely used method. With the required quantum mechanics limited to an indispensable minimum, the book comprehensively treats the basic theoretical and practical aspects of the methodology to educate the reader to the level of an independent EPR researcher in all aspects, including problem posing, sample preparation, machine operation, data collection and interpretation, numerical analysis, and scientific reporting.Many EPR books have been written as expositions of the quantum-mechanical background of magnetic resonance, but without addressing critical practical questions in the lab including but not limited to:what knobs to turnhow to make sampleswhat programs to use (or not use)how to present experimental resultsIntroduction to Practical EPR Spectroscopy offers a complete preparation (both theoretical and practical) to be an independent EPR spectroscopist in what may be a non-specialist laboratory. It is written primarily for PhD, master’s and postdoctoral students and their tutors across biochemistry, organic, inorganic, bioinorganic and physical chemistry, molecular biology, microbiology, molecular physics, materials science, and geology.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 151
    • English
    Advances in Heterocyclic Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors

  • Water Extraction of Bioactive Compounds

    • 2nd Edition
    • Herminia Domínguez + 1 more
    • English
    Water Extraction of Bioactive Compounds: From Plants to Drug Development draws together the expert knowledge of researchers from around the world to outline the essential knowledge and techniques required to successfully extract bioactive compounds for further study or for practical applications. The book is an updated resource for biochemists, medicinal chemists, food technologist, pharmaceutical scientists, chemical engineers and academics working in the discovery and development of drugs from natural sources. The discovery and extraction of bioactive plant compounds from natural sources is of growing interest to functional foods, nutraceuticals, cosmeceuticals and pharmaceutical developers, adding greater fuel to a simultaneous search for efficient, green technologies to support this.Water Extraction of Bioactive Compounds: From Plants to Drug Development is a detailed guide to the fundamental concepts and considerations needed to successfully undertake such processes, supported by application examples and highlighting the most influential variables. Beginning with an introduction to plants as sources of drugs, the book highlights the need for a move towards both more rational and greener techniques in the field and presents multiple innovative water-based strategies for the extraction of bioactive constituents of botanicals. A broad range of available techniques are reviewed, including conventional and pressurized hot water extraction techniques, intensified processes such as microwave-assisted, ultrasound-assisted processes, enzyme assisted extraction, pulsed electric fields, and processes using combined techniques.

  • A Beginner's Guide to Computational Chemistry

    Methods and Applications
    • 1st Edition
    • Volume 28
    • John M. Galbraith + 1 more
    • English
    A Beginner's Guide to Computational Chemistry: Methods and Applications provides a basic discussion of computer functionality through operating systems, system administration, and programming followed by a look at key computational methods for electronic structure methods and molecular mechanics, hybrid methods, and solid-state materials. For each topic, essential non-mathematical information is provided so readers can immediately begin to effectively use computational chemistry software. Sections quickly present essential information regarding the fundamental approaches and applications in a down to earth and uncluttered manner.This book is ideal for is upper level undergraduate and entry level graduate students completely new to the field of computational chemistry, and those with little background knowledge. It is well-suited to entry level courses at this level.

  • Phase Equilibrium Engineering

    • 2nd Edition
    • Volume 13
    • Esteban Alberto Brignole + 1 more
    • English
    Phase Equilibrium Engineering, Second Edition, Volume Thirteen offers a comprehensive study on the application of phase equilibrium tools for chemical process development. This updated edition shifts the focus from computing phase equilibria using thermodynamic relationships to designing and controlling phase conditions essential for various processes. The book emphasizes thermodynamic modeling of mixtures crucial for process synthesis, simulation, design, and optimization, providing updated chapters, new sections, case studies, and additional chapters based on the latest experimental work. The book delves into the relationship between mixture molecular properties, the selection of thermodynamic models, and applicable process technologies. It includes a classification of mixtures, separation processes, thermodynamic models, and technologies to guide engineers. The phase conditions required for reacting systems at subcritical and supercritical conditions are studied. The four cardinal points of phase equilibrium engineering—chemical plant/process, laboratory, phase equilibria modeling, and simulation—are harmonized to improve the design and operation of chemical processes.

  • Analysis of Pesticides and Microplastic: Co-occurrence and Emerging Threats to Life

    • 1st Edition
    • Volume 116
    • English
    Analysis of Pesticides and Microplastic: Co-occurrence and Emerging Threats to Life examines the underexplored, combined effects of pesticides and microplastics—two pervasive, non-biodegradable pollutants whose co-occurrence poses an emerging threat to environmental and human health. Chapters in this new release include Harmful Impacts of Pesticides on Health and Environment, Impact of Pesticides on Aquatic Ecosystems, Plastic Pollution: A Global Threat, Health Risks of Plastic Ingestion, Oceanic and Ecological Threats of Plastic Pollution, Pesticide Biosensors: Technologies and Trends, and much more.Additional sections cover Advances in Pesticide Detection in Soil and Water, Oligonucleotide and Aptamer-Based Biosensing, Nanoparticle-Based Sensing of Nanoplastic, Detection of Plastics in Biological Systems, Coexistence of Pesticides and Nanoplastic: Adsorption Mechanisms, Approaches to Bioremediation of Pesticides and Microplastic, Mitigating Health and Environmental Impacts of Co-Occurrence, and Future Perspectives on Persistent Pollutants, Food Chain Bioaccumulation: Pesticides and Microplastics.

  • New Trends in Cyclodextrin Technology for Pharmaceuticals

    Innovations Based on Cyclodextrins for the Pharmaceutical World
    • 1st Edition
    • Ernesto Rivera García + 1 more
    • English
    New Trends in Cyclodextrins Technology for Pharmaceuticals: Innovations Based on Cyclodextrins for the Pharmaceutical World presents a detailed overview on the properties and applications of cyclodextrins in the pharmaceutical field. The book presents an up-to-date introduction and their properties, exploring current and future methodologies for the use of cyclodextrins in drug delivery systems, biomedical applications, nanomedicine, and in the design dendritic structures and optimize dendrimers are also examined. This new reference is invaluable for researchers studying the development of controlled drug release systems based on cyclodextrins and chemists working in pharmaceuticals or health science.

  • Synthetic Polymer Chemistry

    • 1st Edition
    • Pradip Bhowmik
    • English
    Synthetic Polymer Chemistry provides a comprehensive introduction to polymers and their physical properties, as well as different types of polymerization reactions. The book covers an array of integral topics, from the introduction of polymers and their physical properties, to morphology (crystalline and amorphous phase), and molecular weights measurements and solubility. Different types of polymerization reactions (free radical, cationic, anionic condensation) based on organic reaction mechanisms are also discussed. Users will find this book to be a great resource for students and researchers who want to build a strong foundation of organic chemistry and polymer chemistry.Topics discussed in this resource will provide an important foundation and understanding that helps readers grasp the materials covered in advanced polymer chemistry. It is ideal for courses in polymer chemistry, organic chemistry, materials science and engineering, and biomedical engineering.

  • Hyperspectral Imaging

    • 2nd Edition
    • Jose Manuel Amigo + 1 more
    • English
    Hyperspectral Imaging, Second Edition builds on the foundational insights of the first edition, covering core analytical frameworks and introducing new algorithms, hardware technologies, and cutting-edge applications. By incorporating the latest research findings and case studies, sections provide readers with enhanced tools and techniques for effective hyperspectral and multispectral image analysis across diverse scientific, industrial, and field domains. The book also addresses evolving challenges and fresh opportunities in the field, ensuring that users are equipped with the most current knowledge and practices. It underscores the continued relevance and transformative potential of hyperspectral and multispectral imaging in contemporary research and industry.Graduate students, academics, early researchers, and industry scientists across various disciplines working with hyperspectral and multispectral images, including analytical chemistry, remote sensing, vegetation and crops, food and feed production, forensic sciences, biochemistry, medical imaging, pharmaceutical production, art studies, cultural heritage, and more will find this update extremely useful.

  • Prof. of Drug Substances, Excipients and Related Methodology

    • 1st Edition
    • Volume 52
    • English
    Physical and chemical data, synthesis or degradation pathways, various analytical techniques for identification and quantification, multiple separation methods, and the pharmacology of drug substances are essential at all stages of pharmaceutical development and are invaluable to practitioners; however, they are scattered throughout the scientific literature. The Analytical Profiles of Drug Substances and Excipients compiles this information into a singular source. No other book series delivers this crucial information as swiftly and relevantly. The Profiles series comprises review articles and database compilations organized into five principal categories: Physical Profiles of Drug Substances and Excipients; Analytical Profiles of Drug Substances and Excipients; ADME Profiles of Drug Substances and Excipients; Methodology for the Characterization of Drug Substances and Excipients; and Methods of Chemical Synthesis. The 52nd volume of Profiles of Drug Substances, Excipients, and Related Methodology offers detailed profiles of five pharmaceutical compounds: Pazopanib, Fenofibrate, Sumatriptan, Beclomethasone dipropionate, and Ceftaroline fosamil. This volume contains a review article on Stimuli-Responsive Polymers, detailing their types, classification, and applications in drug delivery.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 136
    • English
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • The Analytical Chemistry of Cannabis

    Chemistry, Pharmacology, Manufacturing, Use, and Control of Medicinal Cannabis and Cannabinoid Dosage Formulations
    • 2nd Edition
    • Brian F. Thomas + 2 more
    • English
    The Analytical Chemistry of Cannabis: Chemistry, Pharmacology, Manufacturing, Use, and Control of Medicinal Cannabis and Cannabinoid Dosage Formulations: Second Edition presents advanced methods in analytical chemistry to address modern issues surrounding cannabis-based products. Since the first edition, the cannabis industry has rapidly expanded its array of recreational and medicinal products. This volume provides crucial methods to support the manufacturing, labeling, and distribution of safe, consistent products with known chemical content and performance. It offers updated information on the chemistry and pharmacology of cannabis and cannabinoids and aims to resolve industry challenges by fostering understanding among scientists, public health officials, and non-scientist stakeholders.The book is valuable for professionals in analytical chemistry, pharmacology, medicine, and law enforcement, as well as for advanced academic courses in related fields.

  • Cheminformatics with Python

    • 1st Edition
    • Volume 26
    • Hongmei Lu + 1 more
    • English
    Cheminformatics with Python provides a ground-up, practical introduction that helps reader make effective use of the software. In four parts, including programming, data, methods, and applications, the book provides a brief introduction to Python language and related scientific computing, cheminformatics, machine learning, and deep learning packages and presents a systematic study of the representation of instrumental data, including molecular structures and common chemical databases. The methods section covers analytical signal processing, multivariate calibration, multivariate resolution, classical machine learning, and deep learning methods. Finally, the application section presents case studies of successful applications of cheminformatics in analytical chemistry, metabolomics, drug discovery, and more.A supporting appendix section and the necessary mathematical, statistical, and information theory-related theories are provided, along with practical tips such as code editors and source code management. Online coding materials on GitHub and an individual Jupyter notebook for each chapter further support practical learning. This book will be a great resource for senior undergraduate students, graduate students, post-docs, and professors primarily in the field of computational and analytical chemistry.

  • Structural Biology of Amyloid Fibrils

    • 1st Edition
    • Vijay Kumar + 1 more
    • English
    Structural Biology of Amyloid Fibrils provides a comprehensive reference on the structure of protein aggregates in different neurodegenerative diseases, along with their molecular bases. Chapters describe these structures in detail, highlighting their similarities and differences across different disease states along with an unprecedented overview of current developments and new hypotheses emerging in amyloid fibril structure, stability and mechanisms of formation. The book also discusses how amyloid structure may affect the ability of fibrils to spread to different sites in a prion-like manner, as well as their role in disease. Featuring chapters on NMR, X-ray crystallography, and Cryo-EM methods, and discussing the structure of amyloid fibrils obtained directly from patients, the book allows readers to understand how polymorphism is associated with disease phenotype and how fibril structure affects and influences the cellular environment. Understanding the molecular architecture of amyloid fibrils and oligomers will be an important step towards developing therapeutic interventions based on targeting the fibrils and oligomers themselves and the processes that generate them.

  • Quantitative Gas Chromatography-Mass Spectrometry in Clinical and Pharmacological Analysis

    Principles and Applications in Lipids and Biomarkers
    • 1st Edition
    • Dimitrios Tsikas
    • English
    Quantitative Gas Chromatography-Mass Spectrometry in Clinical and Pharmacological Analysis: Principles and Applications in Lipids and Biomarkers is an essential resource for researchers, clinicians, and analytical scientists involved in clinical and pharmacological analysis. It provides practical guidance on using gas chromatography-mass spectrometry (GC-MS) and tandem mass spectrometry (GC-MS/MS) for the accurate quantification of physiological substances such as lipids, fatty acids, bile acids, eicosanoids, and biomarkers of oxidative stress like malondialdehyde and isoprostanes. Emphasizing the use of stable isotope-labelled internal standards and chemical ionization techniques, the book enables sensitive and precise measurement of analytes in complex biological samples like blood and urine, supporting disease diagnosis, therapy monitoring, and biomedical research. Designed with a focus on real-world application, it offers step-by-step procedures, troubleshooting tips, and illustrative diagrams to aid understanding. The content covers sample preparation, method validation, and quality control, making it a practical reference for laboratory scientists. Additionally, it highlights recent developments and biomedical applications, providing current knowledge and innovative approaches in the field. Overall, this comprehensive manual bridge analytical techniques with clinical and pharmacological needs, facilitating accurate biomarker analysis to improve health outcomes and scientific understanding.

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