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Elsevier

Breathborne Biomarkers and the Human Volatilome

From Chemistry and Biology to Technology and Applications

  • 3rd Edition - June 1, 2027
  • Latest edition
  • Editors: Jonathan Beauchamp, Cristina Davis
  • Language: English

Breathborne Biomarkers and the Human Volatilome: From Chemistry and Biology to Technology and Applications, Third Edition, is the definitive resource for researchers, clinic… Read more

Description

Breathborne Biomarkers and the Human Volatilome: From Chemistry and Biology to Technology and Applications, Third Edition, is the definitive resource for researchers, clinicians, and industry professionals interested in the power of breath analysis for health and disease monitoring. This comprehensive guide covers the latest scientific discoveries, innovative detection technologies, and practical applications of volatile organic compounds (VOCs) in breath, offering valuable insights into how these biomarkers can be used for early diagnosis, personalized medicine, and environmental exposure assessment. Whether you are developing new diagnostic tools or conducting advanced research, this book provides the essential knowledge needed to unlock the full potential of breath analysis. With in-depth coverage of biomarkers, data analytics, and cutting-edge sensor technologies, this edition bridges fundamental science with real-world applications. It is an ideal reference for scientists, healthcare professionals, and industry innovators aiming to stay at the forefront of this rapidly evolving field. By providing clear explanations, current perspectives, and future directions, Breathborne Biomarkers and the Human Volatilome: From Chemistry and Biology to Technology and Applications, Third Edition empowers readers to harness the power of breath for improved health outcomes and environmental monitoring—making it an indispensable tool in modern biomedical science.

Key features

  • Provides an extensive overview of established biomarkers, cutting-edge detection tools, key disease targets, and specific real-world applications
  • Covers data analytics and study design in detail, offering a complete understanding of how to conduct and interpret breath analysis research
  • Serves as both an accessible primer for newcomers and a comprehensive reference for experienced researchers and professionals

Readership

Academic researchers and medical practitioners, including primarily analytical and bioanalytical chemists, biochemists, cell biologists, physiologists, engineers and clinicians with an interest in breath analysis and researchers in metabolomics and volatilomics

Table of contents

PART A:Concepts in breath analysis

1. Breath biomarkers and the exposome

2. Breath sampling and standardization

3. Physiological modelling of exhaled compounds

PART B: Breath constituents

4. Endogenous volatiles and the breath volatilome

5. Exhaled nitric oxide 6.Exhaled carbon monoxide

7. Exhaled breath condensate and aerosols

PART C: Analytics

8. Selected ion flow tube mass spectrometry

9. Proton transfer reaction—mass spectrometry

10. Ion mobility spectrometry

11. Secondary electrospray ionization

12. Sensor systems

13. Optical spectroscopy

14. Gas chromatography-mass spectrometry

15. High-resolution mass spectrometry

PART D: Breath tests

16. 13C breath tests

17. Breath monitoring in the intensive care unit

18. Chronic obstructive pulmonary disease, smoking and vaping

19. Clinical phenotyping 20.Breath analysis for respiratory infections

21. Volatile biomarkers of viral infections

22. Lifestyle applications

PART E: Beyond human breath

23. Biomarkers in urine and stool

24. Volatile emissions from skin

25. Mammalian bioreactors for volatile emissions

26. Yeast and fungal volatilome

27. Bacterial volatile emissions

PART F: Field applications

28. Breath analysis in law enforcement

29. Drugs in breath

30. Urban search and rescue

31. Breath analysis in constrained environments

32. Breath analysis in occupational medicine

33. Breath biomarkers in human xenobiotic exposure studies

34. Canine olfaction

PART G: Design and interpretation

35. Clinical study design

36. Challenges in clinical breath research development

37. Mathematical interpretation of targeted volatilome data

38. Preprocessing and analysis of volatilome data

Product details

  • Edition: 3
  • Latest edition
  • Published: June 1, 2027
  • Language: English

About the editors

Jonathan Beauchamp

Editor
Jonathan Beauchamp is manager of the Emissions Analytics and Diagnostics group at the Fraunhofer Institute for Process Engineering and Packaging IVV in Freising, Germany. He has been involved in academic and industrial breath research for the past 15 years and is currently principal investigator in several breath-related projects. He is an active member and current treasurer of the International Association of Breath Research (IABR).
Affiliations and expertise
Manager, Emissions Analytics and Diagnostics group, Fraunhofer Institute for Process Engineering and Packaging IVV, Freising, Germany

Cristina Davis

Editor
Cristina Davis is chair and professor of Mechanical and Aerospace Engineering at the University of California Davis, United States. Her research focuses on development of novel chemical and biological sensor systems and biomarker identification in agriculture and human/animal health monitoring. She has 12 issued patents and has coauthored over 100 peer-reviewed journal articles and book chapters. She is current chair-elect of IABR.
Affiliations and expertise
Chair and Professor, Department of Mechanical and Aerospace Engineering, University of California, Davis, CA, USA