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Books in Life sciences

  • Exploring Mathematical Modeling in Biology Through Case Studies and Experimental Activities

    • 1st Edition
    • Rebecca Sanft + 1 more
    • English
    Exploring Mathematical Modeling in Biology through Case Studies and Experimental Activities provides supporting materials for courses taken by students majoring in mathematics, computer science or in the life sciences. The book's cases and lab exercises focus on hypothesis testing and model development in the context of real data. The supporting mathematical, coding and biological background permit readers to explore a problem, understand assumptions, and the meaning of their results. The experiential components provide hands-on learning both in the lab and on the computer. As a beginning text in modeling, readers will learn to value the approach and apply competencies in other settings. Included case studies focus on building a model to solve a particular biological problem from concept and translation into a mathematical form, to validating the parameters, testing the quality of the model and finally interpreting the outcome in biological terms. The book also shows how particular mathematical approaches are adapted to a variety of problems at multiple biological scales. Finally, the labs bring the biological problems and the practical issues of collecting data to actually test the model and/or adapting the mathematics to the data that can be collected.
  • Cancer Health Equity Research

    • 1st Edition
    • Volume 146
    • English
    Cancer Health Equity Research, Volume 146 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Pubertal Mammary Development as a ‘Susceptibility Window’ for Breast Cancer Disparity, Review of Patient Navigation Interventions to Address Barriers to Participation in Cancer Clinical Trials, Racial Disparities in Ovarian Cancer Research, Mighty Men: A Faith-Based Weight Loss Intervention to Reduce Cancer Risk in African American Men, Design of a Patient Navigation Intervention to Increase Rates of Surgery among African Americans with Early-Stage Lung Cancer, and much.
  • Handbook of Algal Science, Technology and Medicine

    • 1st Edition
    • Ozcan Konur
    • English
    Handbook of Algal Science, Microbiology, Technology and Medicine provides a concise introduction to the science, biology, technology and medical use of algae that is structured on the major research fronts of the last four decades, such as algal structures and properties, algal biomedicine, algal genomics, algal toxicology, and algal bioremediation, algal photosystems, algal ecology, algal bioenergy and biofuels. It also covers algal production for biomedicine, algal biomaterials, and algal medicinal foods within these primary sections. All chapters are authored by the leading researchers in their respective research fields. Our society currently faces insurmountable challenges in the areas of biomedicine and energy in the face of increasing global population and diminishing natural resources as well as the growing environmental and economic concerns, such as global warming, greenhouse gas emissions and climate change. Algae offer a way to deal with these challenges and concerns for both sustainable and environment friendly bioenergy production and in biomedicine through the development of crucial biotechnology.
  • Drug Delivery Aspects

    Volume 4: Expectations and Realities of Multifunctional Drug Delivery Systems
    • 1st Edition
    • Ranjita Shegokar
    • English
    Drug Delivery Aspects reviews additional features of drug delivery systems, along with the standard formulation development, like preclinical testing, conversion into solid dosage forms, roles of excipients and polymers used on stability and sterile processing. There is a focus on formulation engineering and related large scale (GMP) manufacturing, regulatory, and functional aspects of drug delivery systems. A detailed discussion on biologics and vaccines gives insights to readers on new developments in this direction. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems.
  • Seaweeds Around the World: State of Art and Perspectives

    • 1st Edition
    • Volume 95
    • English
    Seaweeds around the World: State of Art and Perspectives, Volume 95, includes discussions on current research conducted in the field of algae. Specific chapters cover Isotopic Labeling of Cultured Macroalgae and Isolation of 13C-labeled Cell Wall Polysaccharides for Trophic Investigations, Selected Red Seaweeds from the Philippines with Emerging High-Value Applications, Challenges to the Future Domestication of Seaweed Cultivated Species: Understanding Individual Needs and Physiological Processes for Large-Scale Production, The Importance of Mucilage in Dispersion and Efficiency of Fertilization of Male Gametes, The Application of Seaweeds in Environmental Biotechnology, Indonesian Sargassum Species Prospecting: Potential Applications of Bioactive Compounds, and much more.
  • Principles of Tissue Engineering

    • 5th Edition
    • Robert Lanza + 3 more
    • English
    Now in its fifth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fifth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and the application of tissue-engineering techniques for food production – is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the emerging technologies in the field.
  • Biomechanics and Gait Analysis

    • 1st Edition
    • Nicholas Stergiou
    • English
    Biomechanics and Gait Analysis presents a comprehensive book on biomechanics that focuses on gait analysis. It is written primarily for biomedical engineering students, professionals and biomechanists with a strong emphasis on medical devices and assistive technology, but is also of interest to clinicians and physiologists. It allows novice readers to acquire the basics of gait analysis, while also helping expert readers update their knowledge. The book covers the most up-to-date acquisition and computational methods and advances in the field. Key topics include muscle mechanics and modeling, motor control and coordination, and measurements and assessments. This is the go to resource for an understanding of fundamental concepts and how to collect, analyze and interpret data for research, industry, clinical and sport.
  • Cell Death Regulation in Health and Disease - Part A

    • 1st Edition
    • Volume 351
    • English
    Cell Death Regulation in Health and Disease - Part A, Volume 351, the latest release in the International Review of Cell and Molecular Biology reviews current advances in cell and molecular biology. The series publishes timely topics authored by prominent cell and molecular biologists. This release is part of a 3-part series which comprises a comprehensive view of cell death regulation in a variety of biological contexts. Chapters cover Membrane dynamics in cell death regulation, The role of necroptosis in intestinal dysfunction, Regulation of cell death in the cardiovascular system, Cell death in bacterial and viral infection, and much more.
  • Stem Cell Proliferation and Differentiation

    • 1st Edition
    • Volume 138
    • English
    Stem Cell Proliferation and Differentiation, Volume 138, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
  • Cell-derived Matrices Part A

    • 1st Edition
    • Volume 156
    • English
    Cell-Derived Matrices, Part A, Volume 156, provides a detailed description and step-by-step methods surrounding the use of three-dimensional cell-derived matrices for tissue engineering applications. Biochemical, biophysical and cell biological approaches are presented, along with sample results. Specific chapters cover Anisotropic cell-derived matrices with controlled 3D architecture, Generation of functional fluorescently-labell... cell-derived matrices by means of genetically-modified fibroblasts, Bi-layered cell-derived matrices, Engineering clinically-relevant cell-derived matrices using primary fibroblasts, Decellularized matrices for bioprinting applications, and much more.
  • Functional Foods in Cancer Prevention and Therapy

    • 1st Edition
    • Yearul Kabir
    • English
    Functional Foods in Cancer Prevention and Therapy presents the wide range of functional foods associated with the prevention and treatment of cancer. In recent decades, researchers have made progress in our understanding of the association between functional food and cancer, especially as it relates to cancer treatment and prevention. Specifically, substantial evidence from epidemiological, clinical and laboratory studies show that various food components may alter cancer risk, the prognosis after cancer onset, and the quality of life after cancer treatment. The book documents the therapeutic roles of well-known functional foods and explains their role in cancer therapy. The book presents complex cancer patterns and evidence of the effective ways to control cancers with the use of functional foods. This book will serve as informative reference for researchers focused on the role of food in cancer prevention and physicians and clinicians involved in cancer treatment.
  • Stress and Brain Health: Across the Life Course

    • 1st Edition
    • Volume 150
    • English
    Stress and Brain Health: Across the Life Course, Volume 150, examines up-to-date knowledge on how stress effects brain health. The book's wide-ranging topics include the effects of pre-natal and childhood stress on neurodevelopment and aging. Chapters cover What is stress, how to measure it and effects on brain function, Pre-natal effects of stress on brain development and vulnerability, Stress in childhood, sensitive periods and regulatory mechanisms, The impact of childhood poverty on brain health, Adverse childhood experiences (ACE) on the brain, Stress, aging and epigenetics, The effects of chronic stress on the prefrontal cortex, Neurobiology of resilience to stress, and more.
  • Atlas of the Developing Mouse Brain

    • 2nd Edition
    • George Paxinos + 3 more
    • English
    Atlas of the Developing Mouse Brain, Second Edition builds on the features of successful first edition, providing a comprehensive and convenient reference for all areas of the mouse brain at Fetal-Day 17.5 (E17.5), Day-of-Birth (P0), and Day-Six postnatal (P6). The book also delineates the parts of the eye, features of the skull, ganglia, nerves, arteries, veins, bones and foramina. This atlas is an essential tool for researchers and students who study the development of the mouse brain, or for those who interpret findings from genetic manipulation.
  • Metabolomics for Biomedical Research

    • 1st Edition
    • Jerzy Adamski
    • English
    Metabolomics for Biomedical Research brings together recent progress on study design, analytics, biostatistics and bioinformatics for the success of metabolomics research. Metabolomics represents a very interdisciplinary research prominent in the functional analyses of living systems; hence, this book focuses on translation and medical aspects. The book discusses topics such as biomarkers and their requirements to be used in medical research, with the parameters and approaches on how to validate their quality; and animal models and other approaches, as stem cells and organoid culture. Additionally, it explains how metabolomics may be applied in prediction of individual response to drug or disease progression. This book is a valuable source for researchers on systems biology and other members of biomedical field interested in metabolism-oriented studies for medical research.
  • Neurophysiology in Neurosurgery

    A Modern Approach
    • 2nd Edition
    • Vedran Deletis + 3 more
    • English
    Over the last 18 years, there have been many advances in the field of intraoperative monitoring. This new edition of Neurophysiology in Neurosurgery: A Modern Approach provides updates on the original techniques, as well as other more recent methodologies that may either prove beneficial or are commonly used in neuromonitoring. The purpose of this book is to describe the integration of neuromonitoring with surgical procedures. Each methodology is discussed in detail as well as chapters describing how those methodologies are applied to multiple surgical procedures and the evidence used to support those uses. The second edition features a surgical procedure section, which focuses on specific surgical procedures and the type of monitoring used during these procedures. The original chapters have been updated, expanded, and the structure modified to ensure the book is beneficial to both physiologists and surgeons. This book is written for neurosurgeons, neurophysiologists, neurologists, anesthesiologists, interventional neuroradiologists, orthopedic surgeons, and plastic surgeons.
  • Neurotoxicity of Pesticides

    • 1st Edition
    • Volume 4
    • English
    Neurotoxicity of Pesticides, Volume Four, in this comprehensive serial addresses contemporary advances in neurotoxicology of pesticides by providing authoritative review articles on key issues in the field. Edited by leading subject experts, topics of note in this new release include Organophosphates, OPs, Nerve agents, Pyrethroids, Neonicotinoids and Formamidines, among others.
  • Comparative Kinesiology of the Human Body

    Normal and Pathological Conditions
    • 1st Edition
    • Salih Angin + 1 more
    • English
    Comparative Kinesiology of the Human Body: Normal and Pathological Conditions covers changes in musculoskeletal, neurological and cardiopulmonary systems that, when combined, are the three pillars of human movement. It examines the causes, processes, consequences and contexts of physical activity from different perspectives and life stages, from early childhood to the elderly. The book explains how purposeful movement of the human body is affected by pathological conditions related to any of these major systems. Coverage also includes external and internal factors that affect human growth patterns and development throughout the lifespan (embryo, child, adult and geriatrics). This book is the perfect reference for researchers in kinesiology, but it is also ideal for clinicians and students involved in rehabilitation practice.
  • Biomechanics of Coronary Atherosclerotic Plaque

    From Model to Patient
    • 1st Edition
    • English
    Biomechanics of Coronary Atherosclerotic Plaque: From Model to Patient, First Edition, is the first comprehensive text to focus on important biomechanical studies conducted in the last decade that have increased our understanding of coronary atherosclerotic plaque initiation, growth, and rupture, as well as improving the design of medical devices and clinical interventions, including surgical procedures. The book provides students, researchers, engineers, clinicians, and interventional cardiologists with an overview of the main topics related to the biomechanics of atherosclerosis, in a single volume written by several experts in the field. This volume is part of the Biomechanics of Living Organs book series. The biomechanics of human soft tissues and organs has been an emerging research field since the publication of Y.C. Fung’s original book series in the 1990s. The publication of such books entirely dedicated to a specific biomechanical subject is necessary to advance scientific research in the field of biomechanics and to transfer important knowledge to future generations. Therefore, this series of volumes on the biomechanics of living organs has been created. This series began in July 2017 with the publication of a first volume on the fundamentals of Hyperelastic Constitutive Laws for Finite Element Modeling of Living Organs. The current volume on the Biomechanics of Coronary Atherosclerotic Plaque, is the latest in this new series.
  • Tumor Immunology and Immunotherapy - Integrated Methods Part B

    • 1st Edition
    • Volume 636
    • English
    Tumor Immunology and Immunotherapy - Integrated Methods Part B, Volume 636 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this update include Quantification methods of Transforming Growth Factor beta (TGF˗β) activity in the setting of cancer immunotherapy, Decoding cancer cell death-driven immune cell recruitment: An in vivo method for site-of-vaccination analyses, Tracking and interrogating tissue-resident and recruited microglia in brain tumors, Metabolomics and lipidomics of the tumor microenvironment, Monitoring abscopal responses to radiation in mice, and much more.
  • The Cognitive Approach in Cloud Computing and Internet of Things Technologies for Surveillance Tracking Systems

    • 1st Edition
    • Dinesh Peter + 3 more
    • English
    The Cognitive Approach in Cloud Computing and Internet of Things Technologies for Surveillance Tracking Systems discusses the recent, rapid development of Internet of things (IoT) and its focus on research in smart cities, especially on surveillance tracking systems in which computing devices are widely distributed and huge amounts of dynamic real-time data are collected and processed. Efficient surveillance tracking systems in the Big Data era require the capability of quickly abstracting useful information from the increasing amounts of data. Real-time information fusion is imperative and part of the challenge to mission critical surveillance tasks for various applications. This book presents all of these concepts, with a goal of creating automated IT systems that are capable of resolving problems without demanding human aid.
  • Responsible Genomic Data Sharing

    Challenges and Approaches
    • 1st Edition
    • Xiaoqian Jiang + 1 more
    • English
    Responsible Genomic Data Sharing: Challenges and Approaches brings together international experts in genomics research, bioinformatics and digital security who analyze common challenges in genomic data sharing, privacy preserving technologies, and best practices for large-scale genomic data sharing. Practical case studies, including the Global Alliance for Genomics and Health, the Beacon Network, and the Matchmaker Exchange, are discussed in-depth, illuminating pathways forward for new genomic data sharing efforts across research and clinical practice, industry and academia.
  • Insect Metamorphosis

    From Natural History to Regulation of Development and Evolution
    • 1st Edition
    • Xavier Belles
    • English
    Insect Metamorphosis: From Natural History to Regulation of Development and Evolution explores the origin of metamorphosis, how it evolved, and how it is it regulated. The book discusses insect metamorphosis as a key innovation in insect evolution. With most of the present biodiversity on Earth composed of metamorphosing insects—approximatel... 1 million species currently described, with another 10-30 million still waiting to be discovered, the book delves into misconceptions and past treatments. In addition, the topic of integrating insect metamorphosis into the theory of evolution by natural selection as noted by Darwin in his On the Origin of Species is also discussed. Users will find this to be a comprehensive and updated review on insect metamorphosis, covering biological, physiological and molecular facets, with an emphasis on evolutionary aspects.
  • Lignocellulosics

    Renewable Feedstock for (Tailored) Functional Materials and Nanotechnology
    • 1st Edition
    • Ilari Filpponen + 2 more
    • English
    Lignocellulosics: Renewable Feedstock for (Tailored) Functional Materials and Nanotechnology gives a comprehensive overview of recent advances in using lignocellulosic substrates in materials science and nanotechnology. The functionalization and processing of lignocellulosics are described via a number of examples that cover films, gels, sensors, pharmaceutics and energy storage. In addition to the research related to functional cellulose nanomaterials, there has been an increased interest in research on lignin and lignocellulosics. This book explains how utilizing biomaterials as a raw material allows ambitious reconstruction of smart materials that are green and multifunctional. As lignin as a valuable material has gained a lot of attention in the last few years, shifting from purely extraction and fundamental characterization, and now also focusing on the preparation of exciting materials, such as nanoparticles, readers will find this to be a comprehensive resource on the topic.
  • Nutritional and Health Aspects of Food in South Asian Countries

    • 1st Edition
    • Jamuna Prakash + 2 more
    • English
    Nutritional and Health Aspects of Food in South Asian Countries provides an analysis of traditional and ethnic foods from the South Asia Region, including India, Sri Lanka, Pakistan, Nepal, Bangladesh and Iran. The book addresses the history of use, origin, composition, preparation, ingredient composition, nutritional aspects, and the effects on the health of various foods and food products in each of these countries from the perspective of their Traditional and Ethnic Foods. In addition, the book presents local and international regulations and provides suggestions on how to harmonize regulations and traditional practices to promote safety and global availability of these foods.
  • Measuring Capacity to Care Using Nursing Data

    • 1st Edition
    • Evelyn J.S. Hovenga AM + 1 more
    • English
    Measuring Capacity to Care Using Nursing Data presents evidence-based solutions regarding the adoption of safe staffing principles and the optimum use of operational data to enable health service delivery strategies that result in improved patient and organizational outcomes. Readers will learn how to make better use of informatics to collect, share, link and process data collected operationally for the purpose of providing real-time information to decision- makers. The book discusses topics such as dynamic health care environments, health care operational inefficiencies and costly events, how to measure nursing care demand, nursing models of care, data quality and governance, and big data. The content of the book is a valuable source for graduate students in informatics, nurses, nursing managers and several members involved in health care who are interested in learning more about the beneficial use of informatics for improving their services.
  • Mitochondria Biology

    • 1st Edition
    • Volume 155
    • English
    Methods in Cell Biology Volume 155 provides an update on the step-by-step "how-to" methods to study mitochondrial structure, function and biogenesis contained in the first two editions. As in the previous editions, biochemical, cell biological, and genetic approaches are presented along with sample results, interpretations, and pitfalls for each method. New chapters in this update include Isolation of Mitochondria and Analysis of Mitochondrial Compartments, Isolation of Mitochondria from Animal Cells and Yeast, Isolation and Characterization of Mitochondria-Associa... ER Membranes, Import of Proteins into Mitochondria, Proximity Labeling Methods to Assess Protein-Protein Interactions in Yeast Mitochondria, and more.
  • Exploración neurológica fácil

    • 6th Edition
    • Geraint Fuller
    • Spanish
  • Molecular Aspects of Plant Beneficial Microbes in Agriculture

    • 1st Edition
    • Vivek Sharma + 2 more
    • English
    Molecular Aspects of Plant Beneficial Microbes in Agriculture explores their diverse interactions, including the pathogenic and symbiotic relationship which leads to either a decrease or increase in crop productivity. Focusing on these environmentally-frie... approaches, the book explores their potential in changing climatic conditions. It presents the exploration and regulation of beneficial microbes in offering sustainable and alternative solutions to the use of chemicals in agriculture. The beneficial microbes presented here are capable of contributing to nutrient balance, growth regulators, suppressing pathogens, orchestrating immune response and improving crop performance. The book also offers insights into the advancements in DNA technology and bioinformatic approaches which have provided in-depth knowledge about the molecular arsenal involved in mineral uptake, nitrogen fixation, growth promotion and biocontrol attributes.
  • Profiles of Drug Substances, Excipients, and Related Methodology

    • 1st Edition
    • Volume 45
    • Harry G. Brittain
    • English
    Profiles of Drug Substances, Excipients, and Related Methodology, Volume 45, presents comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. The series encompasses review articles, with this release focusing on Azilsartan Medoxomil, Piroxicam, Carbetapentane Citrate, Emtricitabine, Etrlotinib, Isotretinoin and Meloxicam.
  • Brain-Computer Interfaces

    • 1st Edition
    • Volume 168
    • English
    Brain-Computer Interfacing, Volume 168, not only gives readers a clear understanding of what BCI science is currently offering, but also describes future expectations for restoring lost brain function in patients. In-depth technological chapters are aimed at those interested in BCI technologies and the nature of brain signals, while more comprehensive summaries are provided in the more applied chapters. Readers will be able to grasp BCI concepts, understand what needs the technologies can meet, and provide an informed opinion on BCI science.
  • Infections in Systemic Autoimmune Diseases

    Risk Factors and Management
    • 1st Edition
    • Volume 16
    • English
    Infections in Systemic Autoimmune Diseases: Risk Factors and Management, Volume Sixteen describes the state-of-the-art of the risk factors and management treating the most common systemic autoimmune diseases (SADS). This updated volume consists of an introductory chapter that provides a brief overview of what different types of infectious diseases exist, followed by eight chapters detailing risk factors, guidelines and recommendations per different disease and bacterial infections. International in scope, the list of more than 20 contributors from Europa and America reads like a who’s who of clinical researchers in the field.
  • Dietary Sugar, Salt and Fat in Human Health

    • 1st Edition
    • Harry G. Preuss + 1 more
    • English
    Divided into four main sections, Dietary Sugar, Salt and Fat in Human Health explores the biochemical, pharmacological and medicinal aspects related to the overindulgence of dietary salt, sugar, and fat, along with possible remedies. Beginning with a general overview, the text outlines aspects associated with advancing age and human physiology, such as different aspects of insulin resistance, the advancing age phenomenon, central fat accumulation and metabolic perturbations and the role of the modern Western diet and the influence of dietary sugar, salt, and fat, with particular focus on their relation to multiple biochemical pathophysiological pathways. The second section of the book focuses on the roles of dietary sugars and their correlation with the chronic disease epidemic, with an emphasis on carbohydrate metabolism and its biochemistry, GI absorption, the glycemic index and the influence of fructose. The historical background of dietary sugars is discussed alongside Atkin’s hypothesis, and an overview of the correlation between dietary fibre and the glycemic index, including a chapter on sugar addiction. Section three contains an exhaustive review of the influence of dietary salt and its diverse mechanistic aspects, including salt-sensitive hypertension, contribution of two steroid receptor pathways, vascular NO, intrarenal RAAS system and angiotensin. The fourth section highlights the biochemistry of dietary saturated, polyunsaturated and trans fat and its influence on human health and various diseases, and further explores NAFLD and gender specific problems. Chapters in this section also investigate the benefits of the Mediterranean diet as well as myths related to cholesterol. Collected and carefully organized for researchers in nutrition, physiology, epidemiology, or sensory science, this book will also benefit general practitioners, surgeons, nurses, health professionals and practitioners, and students studying the role of diet in cardiometabolic disorders and disease.
  • Pan-genomics: Applications, Challenges, and Future Prospects

    • 1st Edition
    • Debmalya Barh + 3 more
    • English
    Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and their applications and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided into three sections: the first, an "overview of pan-genomics and common approaches,” brings the main concepts and current approaches on pan-genomics research; the second, “case studies in pan-genomics,” thoroughly discusses twelve case, and the last, “current approaches and future prospects in pan-multiomics”, encompasses the developments on omics studies to be applied on bacteria related studies. This book is a valuable source for bioinformaticians, genomics researchers and several members of biomedical field interested in understanding further bacterial organisms and their relationship to human health.
  • Microbial Endophytes

    Functional Biology and Applications
    • 1st Edition
    • Ajay Kumar + 1 more
    • English
    Microbial Endophytes: Functional Biology and Applications focuses on endophytic bacteria and fungi, including information on foundational endophytes and the latest advances in relevant genomics, proteomics and nanotechnological aspects. The book provides insights into the molecular aspects of plant endophytes and their interactions and applications, also exploring the potential commercialization of endophytic microorganisms and their use as bio fertilizers, in biocontrol, and as bioactive compounds for other sustainable applications. Coverage of important and emerging legal considerations relevant to those working to implement these important bacteria in production processes is also included.
  • Quaternary Ecology, Evolution, and Biogeography

    • 1st Edition
    • Valentí Rull
    • English
    Quaternary Ecology, Evolution, and Biogeography offers an introduction to the study of the ecological and evolutionary processes that have shaped our present biosphere under the influence of glacial-interglacial cycles. Written by an ecologist with paleoecological expertise, this book reviews the climactic changes that have occurred during the last 2.6 million years, along with the responses of organisms and ecosystems. It offers an understanding of the evolutionary origin of extant biodiversity, its biogeographical patterns, and the composition of modern ecological communities. In addition, it explores human evolution and the influence of our activities on the biosphere, especially in the last millennia.This book offers the latest information on how studying the past can contribute to our understanding of present climate issues for a better future, and is an ideal resource for researchers and students in the natural sciences.
  • On Call Neurology

    On Call Series
    • 4th Edition
    • Stephan A. Mayer + 1 more
    • English
    Ideal for any on-call professional, resident, or medical student, this popular reference covers the common problems you’ll encounter while on call in the hospital. On Call Neurology, 4th Edition, by Drs. Randolph S. Marshall and Stephan A. Mayer, fits perfectly in your pocket, ready to provide key information in time-sensitive, challenging situations. You’ll gain speed, skill, and knowledge with every call - from diagnosing a difficult or life-threatening situation to prescribing the right medication.
  • Gradients and Tissue Patterning

    • 1st Edition
    • Volume 137
    • English
    Gradients and Tissue Patterning, Volume 137 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Each chapter is written by an international board of authors.
  • Computational Approaches for Understanding Dynamical Systems: Protein Folding and Assembly

    • 1st Edition
    • Volume 170
    • English
    Computational Approaches for Understanding Dynamical Systems: Protein Folding and Assembly, Volume 170 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Pairwise-Additive and Polarizable Atomistic Force Fields for Molecular Dynamics Simulations of Proteins, Scale-consistent approach to the derivation of coarse-grained force fields for simulating structure, dynamics, and thermodynamics of biopolymers, Enhanced sampling and free energy methods, and much more.
  • La maladie de Parkinson

    • 4th Edition
    • SOFMA + 2 more
    • French
    La maladie de Parkinson est, après la maladie d’Alzheimer, l’affection neurologique la plus répandue au sein de la population après 50 ans. Sa prévalence augmentant avec l’âge, surtout au-delà de 60 ans, on peut prévoir qu’avec le vieillissement de la population, le nombre de patients ne cessera d’augmenter dans les années à venir.La quatrième édition de cet ouvrage, entièrement en couleurs, consacrée à la maladie de Parkinson, rend compte de façon didactique des avancées de ces cinq dernières années, en abordant de façon exhaustive tous les aspects de cette pathologie : l’épidémiologie, l’étiopathogénie, les aspects génétiques, la physiopathologie, les signes moteurs et non moteurs, notamment les troubles cognitifs, psychiques et comportementaux. Un nouveau chapitre dédié aux apports des nouvelles technologies, notamment les enregistrements électrophysiologique... intracérébraux, l’évaluation neurophysiologique de la marche et du contrôle postural ou encore l’actimétrie, vient compléter cette monographie. Le chapitre consacré à la neuropathologie et la physiopathologie, est également entièrement augmenté et mis à jour avec l’approche de l’alpha-synucléine et l’évocation de la controverse autour de l’hypothèse d’un mécanisme de type prion. Les traitements de recours sont regroupés maintenant dans un chapitre spécifique et un nouveau chapitre est proposé sur les indications de la toxine botulique.Ce livre s’adresse aux praticiens et à tous les professionnels de santé, médicaux et paramédicaux, exerçant dans un service de neurologie ou concernés par la pathologie parkinsonienne : neurologues, internes préparant le diplôme d’études spécialisées de neurologie, neuropsychologues, psychiatres, rééducateurs, orthophonistes et kinésithérapeutes.
  • Agri-Food Industry Strategies for Healthy Diets and Sustainability

    New Challenges in Nutrition and Public Health
    • 1st Edition
    • Francisco J. Barba + 2 more
    • English
    Divided into five sections, Agri-Food Industry Strategies for Healthy Diets and Sustainability: New Challenges in Nutrition and Public Health provides an overview of the challenges and future perspectives related to nutrition, public health, and sustainability. The book addresses strategies to reduce fat, trans fat, saturated fat, sugar, and salt consumption, while also exploring the manufacturing, safety, and toxicology of new food manufacturing. This book examines commercial labeling and nutritional education, nutrigenomics and public health, and provides coverage of the valorization of waste and by-products from the food industry. Nutrition researchers and practitioners, food scientists, technologists, engineers, agronomists, food product developers, medical and public health professionals, and postgraduate students focused in food science and nutrition are sure to find this reference work a welcomed addition to their libraries.
  • Vasopressin

    • 1st Edition
    • Volume 113
    • Gerald Litwack
    • English
    Vasopressin, Volume 113 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting updates on timely topics, including Diabetes Insipidus in Pregnancy, Vasopressin Inactivation: Role of Insulin-Regulated Aminopeptidase, Vasotocin and the Origins of the Vasopressin/Oxytocin Receptor Gene Family, Vasopressin V2 Receptor Ligand Recognition, Development and Therapeutic Potential of Vasopressin Synthetic Analog [V4Q5]dDAVP as a Novel Anticancer Agent, Cellular Junctions and Vasopressin, Vasopressin Actions in the Kidney Renin Angiotensin System and its Role in Hypertension and Renal Disease, Oxytocin/Vasopressin... Neuropeptide Signaling in Insects, and much more.
  • International Review of Cell and Molecular Biology

    • 1st Edition
    • Volume 350
    • English
    International Review of Cell and Molecular Biology, Volume 350, covers all aspects of endoplasmic reticulum (ER) biology. With its multiple cellular functions, including ion storage as well protein folding, trafficking and secretion, the regulation of homeostasis within the ER is crucial to organismal health. New sections in this updated volume include DAMP emission upon ER stress, Protein misfolding disordersm Type I interferon response and ER stress, ER and autophagosome biogenesis, Mitochondria-associa... membranes, ER calcium signaling in excitable cells, and ER in viral infections.
  • Drug Delivery Trends

    Volume 3: Expectations and Realities of Multifunctional Drug Delivery Systems
    • 1st Edition
    • Ranjita Shegokar
    • English
    Drug Delivery Trends examines a drift in the pharmaceutical field across the wide range of dosage forms, drug delivery systems (micro and nanoparticulate), at the regulatory front and on new types of therapies in the market. This volume additionally covers the challenges on drug delivery systems in terms of preclinical and current ways of determining quality and the options to solve the challenges associated with this. Most small-medium scale industries and academics struggle with initial regulatory challenges so a detailed discussion on regulatory trend covers the necessary basic understanding of regulatory procedures and provides the required guidance. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems.
  • Toxoplasma Gondii

    The Model Apicomplexan - Perspectives and Methods
    • 3rd Edition
    • Louis M. Weiss + 1 more
    • English
    Toxoplasma gondii: The Model Apicomplexan - Perspectives and Methods, Third Edition, reflects significant advances in the field in the last five years, including new information on the genomics, epigenomics and proteomics of T. gondii, along with a new understanding of the population biology and genetic diversity of this organism. This edition expands information on the effects of T. gondii on human psychiatric disease and new molecular techniques, such as CAS9/CSPR. T gondii remains the best model system for studying the entire Apicomplexa group of protozoans, which includes Malaria, making this new edition essential for a broad group of researchers and scientists.
  • Tumor Immunology and Immunotherapy - Integrated Methods Part A

    • 1st Edition
    • Volume 635
    • English
    Tumor Immunology and Immunotherapy Integrated Methods - Part A, Volume 635 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Specific chapters to this release include Deconvolution of the immunological contexture of mouse tumors with multiplexed immunohistochemistry... High-dimensional multiplexed immunohistochemical characterization of immune contexture in human cancers, Multiplex assay by IHC for melanoma tumor microenvironment evaluation, Characterization of the tumor immune microenvironment by multispectral image analysis of multiplex immunofluorescence images, Phenotyping of immune cells in situ using multispectral imaging quantification, and much more.
  • Giardia and Giardiasis - Part B

    • 1st Edition
    • Volume 107
    • English
    Giardia and Giardiasis Volume 107-Part B, in the Advances in Parasitology series, is dedicated to aspects of cytoskeletal structure of this parasite with an emphasis on insights of new components and their function in trophozoites. Further, microtubule function and its critical involvement in motility, attachment, mitosis and cell division as well as in transitions between developmental stages are reviewed. Also a comprehensive revision in the progress of tools to explore and understand the functional biology of Giardia, its coding and non-coding genes, features and cellular and molecular biology is contained in this volume. Additionally, an exciting perspective on the interactions between Giardia and intestinal epithelial cell by reviewing transcriptomic and proteomic investigations is included along with a state-of-the art of the understanding pathophysiology of giardiasis and of how Giardia can cause post-infectious and extra-intestinal complications. A complete review of current knowledge including commonly prescribed drugs, causes of therapeutic fails, drug resistance mechanisms, strategies for the discovery of new agents for alternative drug therapies is covered.
  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 95
    • English
    Advances in Clinical Chemistry, Volume 95, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with this new release including sections on Advances in diagnostic microfluidics, Vascular and valvular calcification biomarkers, Long noncoding RNAs in cancer: From discovery to therapeutic targets, Exosomes of male reproduction, Tryptophan in health and disease, Biochemistry of blood platelet activation, and the beneficial role of plant oils in cardiovascular diseases.
  • Systems Simulation and Modeling for Cloud Computing and Big Data Applications

    • 1st Edition
    • Dinesh Peter + 1 more
    • English
    Systems Simulation and Modelling for Cloud Computing and Big Data Applications provides readers with the most current approaches to solving problems through the use of models and simulations, presenting SSM based approaches to performance testing and benchmarking that offer significant advantages. For example, multiple big data and cloud application developers and researchers can perform tests in a controllable and repeatable manner. Inspired by the need to analyze the performance of different big data processing and cloud frameworks, researchers have introduced several benchmarks, including BigDataBench, BigBench, HiBench, PigMix, CloudSuite and GridMix, which are all covered in this book. Despite the substantial progress, the research community still needs a holistic, comprehensive big data SSM to use in almost every scientific and engineering discipline involving multidisciplinary research. SSM develops frameworks that are applicable across disciplines to develop benchmarking tools that are useful in solutions development.
  • The Electronic Health Record

    Ethical Considerations
    • 1st Edition
    • Eike-Henner W. Kluge
    • English
    The Electronic Health Record: Ethical Considerations analyses the ethical issues that surround the construction, maintenance, storage, use, linkage, manipulation and communication of electronic health records. Its purpose is to provide ethical guidance to formulate and implement policies at the local, national and global level, and to provide the basis for global certification in health information ethics. Electronic health records (EHRs) are increasingly replacing the use of paper-based records in the delivery of health care. They are integral to providing eHealth, telehealth, mHealth and pHealth - all of which are increasingly replacing direct and personal physician-patient interaction - as well as in the developing field of artificial intelligence and expert systems in health care. The book supplements considerations that are raised by national and international regulations dealing with electronic records in general, for instance the General Data Protection Regulation of the European Union. This book is a valuable resource for physicians, health care administrators and workers, IT service providers and several members of biomedical field who are interested in learning more about how to ethically manage health data.
  • Cognitive Biases in Health and Psychiatric Disorders

    Neurophysiological Foundations
    • 1st Edition
    • Tatjana Aue + 1 more
    • English
    Cognitive Biases in Health and Psychiatric Disorders: Neurophysiological Foundations focuses on the neurophysiological basis of biases in attention, interpretation, expectancy and memory. Each chapter includes a review of each specific bias, including both positive and negative information in both healthy individuals and psychiatric populations. This book provides readers with major theories, methods used in investigating biases, brain regions associated with the related bias, and autonomic responses to specific biases. Its end goal is to provide a comprehensive overview of the neural, autonomic and cognitive mechanisms related to processing biases.