LIMITED OFFER
Save 50% on book bundles
Immediately download your ebook while waiting for your print delivery. No promo code needed.
Biomechanics of Coronary Atherosclerotic Plaque: From Model to Patient, First Edition, is the first comprehensive text to focus on important biomechanical studies conducted… Read more
LIMITED OFFER
Immediately download your ebook while waiting for your print delivery. No promo code needed.
Biomechanics of Coronary Atherosclerotic Plaque: From Model to Patient, First Edition, is the first comprehensive text to focus on important biomechanical studies conducted in the last decade that have increased our understanding of coronary atherosclerotic plaque initiation, growth, and rupture, as well as improving the design of medical devices and clinical interventions, including surgical procedures. The book provides students, researchers, engineers, clinicians, and interventional cardiologists with an overview of the main topics related to the biomechanics of atherosclerosis, in a single volume written by several experts in the field.
This volume is part of the Biomechanics of Living Organs book series. The biomechanics of human soft tissues and organs has been an emerging research field since the publication of Y.C. Fung’s original book series in the 1990s. The publication of such books entirely dedicated to a specific biomechanical subject is necessary to advance scientific research in the field of biomechanics and to transfer important knowledge to future generations. Therefore, this series of volumes on the biomechanics of living organs has been created. This series began in July 2017 with the publication of a first volume on the fundamentals of Hyperelastic Constitutive Laws for Finite Element Modeling of Living Organs. The current volume on the Biomechanics of Coronary Atherosclerotic Plaque, is the latest in this new series.
Part 1: Biology, Physiopathology, Hemodynamics, Myogenic Responses and Clinical Intravascular Imaging of the Coronary Vascular Wall
1. Biomechanical Regulation of Endothelial Function in Atherosclerosis
2. Molecular mechanisms of the vascular responses to hemodynamic forces
3. Advanced atherosclerotic plaques in animal models versus human lesions: key elements to translation
4. Modeling the Glagov’s compensatory enlargement of human coronary atherosclerotic plaque
5. Measuring coronary arterial compliance and vasomotor response in clinical and research settings
6. Coronary intravascular ultrasound and optical coherence tomography imaging and clinical contexts in coronary hemodynamics
7. The interaction of biochemical, biomechanical and clinical factors of coronary disease: review and outlook
Part 2: Modeling Blood Flow in Arterial Branches and Bifurcations
8. Local blood flow parameters and atherosclerosis in coronary artery bifurcations
9. Effect of regional analysis methods on assessing the association between wall shear stress and coronary artery disease progression in the clinical setting
10. Hemodynamic disturbance due to serial stenosis in human coronary bifurcations: A computational fluid dynamics study
11. Hemodynamic perturbations due to the presence of stents
12. A new reduced-order model to assess the true fractional flow reserve of a left main coronary artery stenosis with downstream lesions and collateral circulations: an in vitro study
Part 3: Fluid-Structure Interaction, Stress Distribution and Plaque Rupture in Arterial Wall
13. In vitro, primarily microfluidic models for atherosclerosis
14. Prediction of the coronary plaque growth and vulnerability change by using patient-specific 3D FSI models based on intravascular ultrasound and optical coherence tomography follow-up data
15. Atheromatous plaque initiation and growth: a multiphysical process explored by an in-silico mass transport model
16. Emergent biomechanical factors predicting vulnerable coronary atherosclerotic plaque rupture
17. Microcalcifications and plaque rupture
18. Identification of coronary plaque mechanical properties from ex-vivo testing
19. Importance of residual stress and basal tone in healthy and pathological human coronary arteries
Part 4: Imaging Inflammatory Biomarkers for in vivo Intravascular Plaque Characterization
20. Intravascular ultrasound imaging of human coronary atherosclerotic plaque: novel morpho-elastic biomarkers of instability
21. Magnetic resonance elastography for arterial wall characterization
22. Noninvasive ultrafast ultrasound for imaging the coronary vasculature and assessing the arterial wall’s biomechanics
23. Pulse wave imaging for the mechanical assessment of atherosclerotic plaques
Part 5: Stenting, Coated Balloon, Drug Elution Systems and Modelling
24. Structure-function relation in the coronary artery tree: theory and applications in interventional cardiology
25. Sequential technique for the stenting of a coronary bifurcation: the re-proximal optimizing technique strategy
26. Modeling the stent deployment in coronary arteries and coronary bifurcations
27. The coated balloon protocol: An emergent clinical technique
28. Endovascular drug delivery and drug-elution systems
JO
Jacques Ohayon is Professor of Mechanics at the Engineering school Polytech, Univ. Savoie Mont-Blanc, France. From 1985 to 1988, he was visiting fellow at the Biomedical Engineering Branch of the National Institutes of Health (NIH), Bethesda MD, USA. He received the 1998 Junior Prize of the French Biomechanics Society (SB) for his research on the biomechanics of the left ventricle. His current research focuses on the biomechanics of atherosclerotic plaque and the development of new clinical tools for imaging the elasticity of vulnerable plaques. From 2006 to 2007, he was visiting professor at the National Institute of Biomedical Imaging and Bioengineering at the NIH, USA. Jacques Ohayon was the Chairman of the SB, which also awarded him the Senior Prize in 2016 for his work on the biomechanics of coronary plaque rupture. In 2020, he was a visiting professor at Texas A & M University and conducted his research in the field of endothelial cell mechanobiology at the Houston Methodist Research Institute (HMRI). Since 2020, he is also Adjunct Professor of Cardiovascular Sciences at HMRI, Texas, USA.
GF
RP