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Elsevier

Pan-genomics: Applications, Challenges, and Future Prospects

  • 1st Edition - March 6, 2020
  • Latest edition
  • Editors: Debmalya Barh, Siomar C. Soares, Sandeep Tiwari, Vasco Ariston De Car Azevedo
  • Language: English

Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and… Read more

Description

Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and their applications and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided into three sections: the first, an "overview of pan-genomics and common approaches,” brings the main concepts and current approaches on pan-genomics research; the second, “case studies in pan-genomics,” thoroughly discusses twelve case, and the last, “current approaches and future prospects in pan-multiomics”, encompasses the developments on omics studies to be applied on bacteria related studies.

This book is a valuable source for bioinformaticians, genomics researchers and several members of biomedical field interested in understanding further bacterial organisms and their relationship to human health.

Key features

  • Covers the entire spectrum of pangenomics, highlighting the use of specific approaches, case studies and future perspectives
  • Discusses current bioinformatics tools and strategies for exploiting pangenomics data
  • Presents twelve case studies with different organisms in order to provide the audience with real examples of pangenomics applicability

Readership

bioinformaticians, genomics scientists, microbiologists, graduate students on diverse related fields

Table of contents

1. Overview, applications, and future perspectives of Pan-genomicsSiomar de Castro Soares2. Bioinformatics approaches applied in Pan-genomics and their challenges Rommel Thiago Juca Ramos Sr.3. Evolutionary pan-genomics and applicationsBasant K. Tiwary4. Insights into old and new enemies: Pan-genomics of Corynebacterium diphtheriae and Corynebacterium ulceransAndreas Burkovski5. Pan-genomics of Veterinary pathogens: Corynebacterium psedotuberculosis Vasco Ariston de Carvalho Azevedo6. Pan-genomics of Plant pathogens and its applicationsRabia Amir7. Pan-genomics food pathogens and its applicationsUlisses de Padua Pereira II8. Pan-genomics of aquatic animal pathogens and its applicationsNguyen Thanh Luan and Pham Thi Hai Ha9. Pan-genomics of model bacteria and their outcomes Amjad Ali10. Pan-genomics of multi drug-resistant human pathogenic bacteria and their resistomeMauricio Corredor Sr.11. Pan-genomics of Virus and its applicationsLuiz Alcantara12. Pan-genomics of Fungi and its applicationsAristóteles Góes-Neto13. Pan-genomics of Algae and applications Jaspreet Kaur14. Pan-genomics of Plants and its applicationsRabia Amir15. Pan-cancer analysis and applications Dipali Dhawan16. Reverse vaccinology and drug target identification through Pan-genomics Amjad Ali17. Pan-metagenomics and its applicationsRanjith Kumavath Sr.18. Pan-transcriptomics and its applicationsAttya Bhatti19. Pan-proteomics and its applicationsWanderson Marques20. Pan-metabolomics and its applications Li Bao and Xiaofeng Liu21. Pan-interactomics and its applicationsDinesh Kumar Yadav

Product details

  • Edition: 1
  • Latest edition
  • Published: March 6, 2020
  • Language: English

About the editors

DB

Debmalya Barh

Dr. Debmalya Barh is currently a Visiting Full Professor (Titular, Grade-E) in Bioinformatics and Precision Health at the Department of Genetics, Ecology, and Evolution, ICB, Federal University of Minas Gerais, Brazil and honorary scientist of the Institute of Integrative Omics and Applied Biotechnology (IIOAB), India. With over 20 years of experience, he has led academic, healthcare, molecular diagnostic, and bioinformatics industry endeavors. He works with more than 400 scientists from 100+ top ranked organizations across 40+ countries and has 220+ publications and a branded editor for 10+ cutting-edge omics related reference books. He is an expert in in precision/personalized health and integrative omics-based biomarker and target discovery in infectious and complex lifestyle diseases.
Affiliations and expertise
Federal University of Minas Gerais, Belo Horizonte, Brazil

SS

Siomar C. Soares

Dr Soares holds a degree in Biomedicine, with special training in Bioinformatics, Master's Degree and PhD in Genetics by Federal University of Minas Gerais – UFMG, the latter with one year of study at the Center for Biotechnology (CeBiTec), Universität Bielefeld. He holds a Post-doctorate in Bioinformatics by UFMG. He was Senior Researcher Bioinformatics at the Central Official Laboratory of the Brazilian Ministry of Fisheries and Aquaculture (2014-2015). He is currently Professor at Federal University of the Triângulo Mineiro (UFTM) since 2015, Secretary of the Southeastern regional of the Brazilian Society of Genetics (2017-current), Substitute Coordinator of the undergraduate course in Biomedicine at UFTM (2017-current) and Substitute Research and Technology Development Coordinator of UFTM (2017-current). His research interests are molecular genetics, genomic sequencing and comparative genomics of microorganisms, focusing on pan-genomics, genomic plasticity in the identification of islands of pathogenicity and virulence factors, phylogenomics, molecular epidemiology, reverse vaccination and software development.
Affiliations and expertise
Professor, Department of Immunology, Microbiology and Parasitology, Institute of Biological Sciences and Natural Sciences, Federal University of Triangulo Mineiro (UFTM), Brazil

ST

Sandeep Tiwari

Dr. Tiwari obtained his BSc from Deen Dayal Upadhyaya Gorakhpur University, MSc in bioinformatics from Devi Ahilya University, and PhD in bioinformatics from the Department of Genetics, Ecology and Evolution, Federal University of Minas Gerais, Brazil. He is a Guest Associate Editorial Board of Frontier in Genetics and frequently serves as an external reviewer for PeerJ and Frontiers. His main areas of expertise are molecular genetics, genomic sequencing, and comparative genomics of microorganisms, with a focus on pan-genomics, genomic plasticity in the identification of pathogenicity islands and virulence factors for drug discovery, phylogenomic, molecular epidemiology, reverse vaccinology, and immunoinformatic.

Affiliations and expertise
Visiting Adjunct Professor, Department of Microbiology, Institute of Biology, Federal University of Bahia, Salvador, BA, Brazil; Department of Immunology, Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil

VA

Vasco Ariston De Car Azevedo

Dr. Vasco Azevedo is a full professor at the Department of Genetics, Ecology, and Evolution, Institute of Biological Sciences, Federal University of Minas Gerais, Brazil. He is a CNPq (Conselho Nacional de Desenvolvimento Científico e Tecnológico) researcher 1A, member of the Brazilian Academy of Sciences, Commander of the Order of Scientific Merit of the MCTI of the genetics advisory committee and the public policy working group on biotechnology and genetic resources of COBRG/CNPq, coordinator of the Associated International Laboratory Bactinfl from INRAE and UFMG, and vice-president of the Brazilian Association of Bioinformatics and Computational Biology. He holds a degree in veterinary medicine from the School of Veterinary Medicine of the Federal University of Bahia (1986), a master's degree (1989), a doctorate (1993) in the genetics of microorganisms from the Institut National Agronomique Paris Grignon, and a doctorate in bioinformatics from UFMG (2017). He did his postdoctorate work with the Department of Microbiology, School of Medicine, University of Pennsylvania, United States (1994). He was a professor at the Institute of Biomedical Sciences of the University of São Paulo (2004). He is an expert in genetics and bioinformatics and his work mainly focuses on genomics, transcriptomics, proteomics, metabolomics, vaccine development, diagnostics, and the development of next generation probiotics. He has more than 600 scientific publications, 14 books, and 60 chapters as well as 12 patents.
Affiliations and expertise
Professor, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), Brazil

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