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Elsevier

Books in Life sciences

  • PAKs, RAC/CDC42 (p21)-activated Kinases

    Towards the Cure of Cancer and Other PAK-dependent Diseases
    • 1st Edition
    • Hiroshi Maruta
    • English
    This book covers a variety of cutting-edge basic and clinical PAK research ranging from laboratory benches to hospital beds. The goal of this book is to inspire not only biomedical research scientists and university students, but also a variety of patients who suffer from PAK-dependent diseases and clinical doctors who try to cure or delay these PAK-dependent diseases.This book consists of 9 chapters which deal with different aspects of this kinase. These chapters are written by more than two dozen world-leading PAK experts. Each of these will provide updated biomedical information as well as future insight to a wide range of readers who are interested in this unique kinase and both its pathological and physiological roles as well as its functional evolution from its ancestral origins.

  • Accurate Results in the Clinical Laboratory

    A Guide to Error Detection and Correction
    • 1st Edition
    • Amitava Dasgupta + 1 more
    • English
    This practical, easy-to-use guide, named to Doody’s Core Titles 2013, addresses interference issues in all laboratory tests, including patient epigenetics, process of specimen collection, enzymes, biomarkers. Clinicians and laboratory scientists can therefore rely on one reference which speaks to both their needs of accurate specimen analysis and optimal patient care. Erroneous hospital and pathology laboratory results can be confusing and problematic, especially in acute care situations. While some factors creating interference, can be identified in the laboratory, detecting many others is often dependent on clinical details unavailable to the laboratory scientists or pathologists. Therefore, clinicians must become proficient in identifying such erroneous reports, and working with pathologists and laboratory scientists so that they can understand the source of such interferences, correct the results, and then decide what course of action must be followed for proper patient management.

  • Ligand Efficiency Indices for Drug Discovery

    Towards an Atlas-Guided Paradigm
    • 1st Edition
    • Celerino Abad-Zapatero
    • English
    The purpose of Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm is to introduce in a concise and self-contained form the concepts, ideas, applications and examples of efficiency-driven drug discovery to the biomedical community at large. The book emphasizes the use of 'new variables' and more objective numerical methods to drive drug discovery in an encompassing way. These 'new variables' are based on Ligand Efficiency Indices (LEIs) formulated in a way that permits mapping Chemico-Biological Space (CBS) in an Atlas-like representation. It provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery. This book emphasizes the use of a graphical representation and objective numerical methods to drive drug discovery more effectively. It presents the definition of LEIs and the corresponding efficiency planes within an atlas-like environment to provide a robust graphical and numerical framework for medicinal chemists and drug-discoverers.

  • Open Innovation in the Food and Beverage Industry

    • 1st Edition
    • Marian Garcia Martinez
    • English
    Food and beverage companies are increasingly choosing to enhance internal idea development by pursuing an ‘open innovation’ approach, allowing the additional exploitation of external ideas and paths to market. Drawing on a range of important case studies, Open innovation in the food and beverage industry investigates the challenges and opportunities afforded by the incorporation of open innovation into the food industry.Part one provides a comprehensive overview of the changing nature of innovation in the food and drink industry, acknowledging trends and considering the implications and impact of open innovation. Part two then reviews the role of partners and networks in open innovation, with collaboration, co-creation of value with consumers, the effectiveness of cluster organizations and the importance of network knowledge all discussed, before part three goes on to explore the establishment and varied management aspects of open innovation partnerships and networks. Finally, open-innovation tools, processes and managerial frameworks are the focus of part four, with discussion of the development, application and psychology of a range of initiatives.With its distinguished editor and international team of expert contributors, Open innovation in the food and beverage industry is a unique guide to the implementation and management of open innovation for all food industry professionals involved in management, research and product development, as well as academics with an interest in open innovation across all industries.

  • The Psychology of Learning and Motivation

    • 1st Edition
    • Volume 58
    • English
    The Psychology of Learning and Motivation series publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving.

  • The Immunoassay Handbook

    Theory and Applications of Ligand Binding, ELISA and Related Techniques
    • 4th Edition
    • David Wild
    • English
    The fourth edition of The Immunoassay Handbook provides an excellent, thoroughly updated guide to the science, technology and applications of ELISA and other immunoassays, including a wealth of practical advice. It encompasses a wide range of methods and gives an insight into the latest developments and applications in clinical and veterinary practice and in pharmaceutical and life science research. Highly illustrated and clearly written, this award-winning reference work provides an excellent guide to this fast-growing field. Revised and extensively updated, with over 30% new material and 77 chapters, it reveals the underlying common principles and simplifies an abundance of innovation. The Immunoassay Handbook reviews a wide range of topics, now including lateral flow, microsphere multiplex assays, immunohistochemistry... practical ELISA development, assay interferences, pharmaceutical applications, qualitative immunoassays, antibody detection and lab-on-a-chip. This handbook is a must-read for all who use immunoassay as a tool, including clinicians, clinical and veterinary chemists, biochemists, food technologists, environmental scientists, and students and researchers in medicine, immunology and proteomics. It is an essential reference for the immunoassay industry. Provides an excellent revised guide to this commercially highly successful technology in diagnostics and research, from consumer home pregnancy kits to AIDS testing.www.immunoas... is a great resource that we put a lot of effort into. The content is designed to encourage purchases of single chapters or the entire book. David Wild is a healthcare industry veteran, with experience in biotechnology, pharmaceuticals, medical devices and immunodiagnostics, which remains his passion. He worked for Amersham, Eastman-Kodak, Johnson & Johnson, and Bristol-Myers Squibb, and consulted for diagnostics and biotechnology companies. He led research and development programs, design and construction of chemical and biotechnology plants, and integration of acquired companies. Director-level positions included Research and Development, Design Engineering, Operations and Strategy, for billion dollar businesses. He retired from full-time work in 2012 to focus on his role as Editor of The Immunoassay Handbook, and advises on product development, manufacturing and marketing.

  • Animal Metamorphosis

    • 1st Edition
    • Volume 103
    • English
    This new volume of Current Topics in Developmental Biology covers recent progresses in our understanding of animal metamorphosis. Over a dozen of leading experts reviews studies ranging from morphological, molecular to genetic analyses of metamorphosis in a broad spectrum of animals, including insects, fish. Topics include molecular evolution in metamorphosis, the synthesis and function of hormones in regulating metamorphic timing and rate, regulation and function of nuclear hormone receptors, neuroendocrine control of metamorphosis, tissue specific metamorphic events such as autophagy and stem cell development, and applications of genome-wide analysis technologies for studying metamorphosis.

  • G Protein Coupled Receptors

    Structure
    • 1st Edition
    • Volume 520
    • English
    This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers G protein coupled receptors and includes chapters on such topics as post-translation modification of GPCR in relationship to biased agonism, structure-based virtual screening, and GPCR oligomerization in the brain.

  • Fish Physiology: Euryhaline Fishes

    • 1st Edition
    • Volume 32
    • Stephen D. McCormick + 2 more
    • English
    The need for ion and water homeostasis is common to all life. For fish, ion and water homeostasis is an especially important challenge because they live in direct contact with water and because of the large variation in the salt content of natural waters (varying by over 5 orders of magnitude). Most fish are stenohaline and are unable to move between freshwater and seawater. Remarkably, some fishes are capable of life in both freshwater and seawater. These euryhaline fishes constitute an estimated 3 to 5% of all fish species. Euryhaline fishes represent some of the most iconic and interesting of all fish species, from salmon and sturgeon that make epic migrations to intertidal mudskippers that contend with daily salinity changes. With the advent of global climate change and increasing sea levels, understanding the environmental physiology of euryhaline species is critical for environmental management and any mitigative measures. This volume will provide the first integrative review of euryhalinity in fish. There is no other book that focuses on fish that have the capacity to move between freshwater and seawater. The different challenges of salt and water balance in different habitats have led to different physiological controls and regulation, which heretofore has not been reviewed in a single volume.

  • International Review of Cell and Molecular Biology

    • 1st Edition
    • Volume 301
    • Kwang W. Jeon
    • English
    International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth.

  • Decision Making: Neural and Behavioural Approaches

    • 1st Edition
    • Volume 202
    • English
    This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields.This volume explores interdisciplinary research on decision making taking a neural and behavioural approach

  • G Protein-Coupled Receptors in Energy Homeostasis and Obesity Pathogenesis

    • 1st Edition
    • Volume 114
    • English
    Obesity is an epidemic with enormous health, economic and social burdens. Current drugs for obesity treatment are far from ideal in terms of efficacy and side effects. Reviews in this volume of Progress in Molecular Biology and Translational Science summarize current status in studies of a number of G protein-coupled receptors that were shown to be promising targets for obesity treatments. Some of these receptors also cause monogenic obesity in humans.

  • Advances in Agronomy

    • 1st Edition
    • Volume 119
    • English
    Advances in Agronomy continues to be recognized as a leading reference and a first-rate source for the latest research in agronomy. As always, the subjects covered are varied and exemplary of the myriad of subject matter dealt with by this long-running serial

  • Encyclopedia of Biological Chemistry

    • 2nd Edition
    • William J. Lennarz + 1 more
    • English
    The 4-volume Encyclopedia of Biological Chemistry, Second Edition, represents the current state of a dynamic and crucial field of study. The Encyclopedia pulls together over 500 articles that help define and explore contemporary biochemistry, with content experts carefully chosen by the Editorial Board to assure both breadth and depth in its coverage.Editors-In-... William J. Lennarz and M. Daniel Lane have crafted a work that proceeds from the acknowledgement that understanding every living process-from physiology, to immunology, and genetics-is impossible without a grasp on the basic chemistry that provides its underpinning. Each article in the work provides an up-to-date snapshot of a given topic, written by experts, as well as suggestions for further readings for students and researcher wishing to go into greater depth.Available on-line via SciVerse ScienceDirect, the functionality of the Encyclopedia will provide easy linking to referenced articles, electronic searching, as well an online index and glossary to aid comprehension and searchability.

  • Laboratory Methods in Cell Biology: Imaging

    • 1st Edition
    • Volume 113
    • English
    Cell biology spans among the widest diversity of methods in the biological sciences. From physical chemistry to microscopy, cells have given up with secrets only when the questions are asked in the right way! This new volume of Methods in Cell Biology covers laboratory methods in cell biology, and includes methods that are among the most important and elucidating in the discipline, such as bioluminescent imaging of gene expressions, confocal imaging, and electron microscopy of bone.

  • Encyclopedia of Sleep

    • 1st Edition
    • Clete Kushida
    • English
    In a world of 24-hour media saturation, sleep has become an increasingly fraught enterprise. The award-winning four-volume Encyclopedia of Sleep, Four Volume Set is the largest reference, either online or in print, on the subject of sleep. Written to be useful for the novice and the established researcher and clinician, Topic areas will include sleep across the life cycle and in other species, sleep and women, sleep and the elderly, pediatric sleep, sleep deprivation and loss, sleep mechanisms, sleep physiology and pathophysiology, sleep disorders, neurobiology, chronobiology, pharmacology, and impact of other disorders on sleep. Recognizing the many fields that are connected to sleep science, the editorial team has been carefully chosen to do justice to this highly interdisciplinary field of study. The steady growth of researchers and clinicians in the sleep field attests to the continued interest in the scientific study of sleep and the management of patients with sleep disorders, and anyone involved in this exciting field should find this work to be an invaluable reference.

  • Implantable Sensor Systems for Medical Applications

    • 1st Edition
    • Andreas Inmann + 1 more
    • English
    Implantable sensor systems offer great potential for enhanced medical care and improved quality of life, consequently leading to major investment in this exciting field. Implantable sensor systems for medical applications provides a wide-ranging overview of the core technologies, key challenges and main issues related to the development and use of these devices in a diverse range of medical applications.Part one reviews the fundamentals of implantable systems, including materials and material-tissue interfaces, packaging and coatings, microassembly, electrode array design and fabrication, and the use of biofuel cells as sustainable power sources. Part two goes on to consider the challenges associated with implantable systems. Biocompatibility, sterilization considerations and the development of active implantable medical devices in a regulated environment are discussed, along with issues regarding data protection and patient privacy in medical sensor networks. Applications of implantable systems are then discussed in part three, beginning with Microelectromechanic... systems (MEMS) for in-vivo applications before further exploration of tripolar interfaces for neural recording, sensors for motor neuroprostheses, implantable wireless body area networks and retina implants.With its distinguished editors and international team of expert contributors, Implantable sensor systems for medical applications is a comprehensive guide for all those involved in the design, development and application of these life-changing technologies.

  • Advances in Agronomy

    • 1st Edition
    • Volume 118
    • English
    Advances in Agronomy continues to be recognized as a leading reference and a first-rate source for the latest research in agronomy. As always, the subjects covered are varied and exemplary of the myriad of subject matter dealt with by this long-running serial

  • Proteomic Profiling and Analytical Chemistry

    The Crossroads
    • 1st Edition
    • Pawel Ciborowski + 1 more
    • English
    Proteomic Profiling and Analytical Chemistry helps scientists without a strong background in analytical chemistry to understand basic analytical principles and apply them to proteomics profiling. In most proteomic profiling experiments, liquid chromatography is used; this method is also used widely in analytical chemistry. This book bridges the gap between overly specialized courses and books in mass spectrometry, proteomics and analytical chemistry. It also helps researchers with an analytical chemistry background to break into the proteomics field. Proteomic Profiling and Analytical Chemistry focuses on practical applications for proteomic research helping readers to design better experiments and to more easily interpret, analyze and validate the resulting data. Experimental aspects such as sample preparation, protein extraction and precipitation, gel electrophoresis, microarrays, dynamics of fluorescent dyes, and more are all covered in detail.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 59
    • English
    Volume 59 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology.

  • Introduction to Forestry and Natural Resources

    • 1st Edition
    • Donald L. Grebner + 2 more
    • English
    Introduction to Forestry and Natural Resources presents a broad overview of the profession of forestry. The book details several key fields within forestry, including forest health, economics, policy, utilization, and forestry careers. Chapters deal specifically with forest products and harvesting, recreation, wildlife habitats, tree anatomy and physiology, and ethics. These topics are ideal for undergraduate introductory courses and include numerous examples (mainly graphical) and questions for students to ponder. Unlike other introductory forestry texts, which focus largely on forest ecology rather than practical forestry concepts, Introduction to Forestry and Natural Resources encompasses economic, ecological, and social aspects providing a uniquely balanced text. The wide range of experience of the contributing authors equips them especially well to identify missing content from other texts in the area and address topics currently covered in corresponding college courses.

  • The Role of Sphingolipids in Cancer Development and Therapy

    • 1st Edition
    • Volume 117
    • English
    Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. This thematic volume looks at "The Role of Sphingolipids in Cancer Development and Therapy"

  • Designing Science Presentations

    A Visual Guide to Figures, Papers, Slides, Posters, and More
    • 1st Edition
    • Matt Carter
    • English
    Designing Science Presentations guides researchers and graduate students of virtually any discipline in the creation of compelling science communication. Most scientists never receive formal training in the creation, delivery, and evaluation of such material, yet it is essential for publishing in high-quality journals, soliciting funding, attracting lab personnel, and advancing a career. This clear, readable volume fills that gap and provides visually intensive guidance at every step—from the construction of original figures to the presentation and delivery of those figures in papers, slideshows, posters, and websites. It provides pragmatic advice on the preparation and delivery of exceptional scientific presentations; demonstrates hundreds of visually striking presentation techniques, giving readers inspiration for creating their own; and is structured so that readers can easily find answers to particular questions.

  • Nonclinical Study Contracting and Monitoring

    A Practical Guide
    • 1st Edition
    • William F. Salminen + 2 more
    • English
    Nonclinical Study Contracting and Monitoring: A Practical Guide offers a systematic and straightforward handbook for obtaining high quality preclinical Good Laboratory Practice (GLP) studies. This book is full of real-world examples, processes, procedures, useful templates, checklists and sample reports to provide readers with a better understanding of exactly what happens during all stages of a GLP study and the critical aspects of GLP study design and conduct. Designed for both the novice and experienced scientist, this book covers the GLP regulations and how they impact preclinical studies, the differences between GLP, non-GLP and peer-reviewed studies, preclinical GLP study design, laboratory selection, contracts and business ethics, how to obtain test material for the study, animal sourcing and release for study, preparation of a draft report and much more. By illustrating the overall big picture and tying it together with the individual steps, this book is an essential resource to help scientists ensure a high quality GLP study that passes both scientific and regulatory scrutiny.

  • The Dictionary of Cell and Molecular Biology

    • 5th Edition
    • John M. Lackie
    • English
    The Dictionary of Cell and Molecular Biology, Fifth Edition, provides definitions for thousands of terms used in the study of cell and molecular biology. The headword count has been expanded to 12,000 from 10,000 in the Fourth Edition. Over 4,000 headwords have been rewritten. Some headwords have second, third, and even sixth definitions, while fewer than half are unchanged. Many of the additions were made to extend the scope in plant cell biology, microbiology, and bioinformatics. Several entries related to specific pharmaceutical compounds have been removed, while some generic entries (“alpha blockers,” “NSAIDs,” and “tetracycline antibiotics,” for example), and some that are frequently part of the experimentalist’s toolkit and probably never used in the clinic, have been retained. The Appendix includes prefixes for SI units, the Greek alphabet, useful constants, and single-letter codes for amino acids.

  • Fluorescence-Based Biosensors

    From Concepts to Applications
    • 1st Edition
    • Volume 113
    • English
    One of the major challenges of modern biology and medicine consists in finding means to visualize biomolecules in their natural environment with the greatest level of accuracy, so as to gain insight into their properties and behaviour in a physiological and pathological setting. This has been achieved thanks to the design of novel imaging agents, in particular to fluorescent biosensors. Fluorescence Biosensors comprise a large set of tools which are useful for fundamental purposes as well as for applications in biomedicine, drug discovery and biotechnology. These tools have been designed and engineered thanks to the combined efforts of chemists and biologists over the last decade, and developed hand in hand together with imaging technologies. This volume will convey the many exciting developments the field of fluorescent biosensors and reporters has witnessed over the recent years, from concepts to applications, including chapters on the chemistry of fluorescent probes, on technologies for monitoring protein/protein interactions and technologies for imaging biosensors in cultured cells and in vivo. Other chapters are devoted to specific examples of genetically-encoded reporters, or to protein and peptide biosensors, together with examples illustrating their application to cellular and in vivo imaging, biomedical applications, drug discovery and high throughput screening.

  • Epigenetic Regulation in the Nervous System

    Basic Mechanisms and Clinical Impact
    • 1st Edition
    • J. David Sweatt + 3 more
    • English
    Epigenetic Regulation in the Nervous System addresses current understanding of the roles of epigenetic processes at the molecular/cellular level, their impact on neural development and behavior, and the potential roles of these mechanisms in neurological and psychiatric disorders. This award-winning volume spans molecular epigenetics, development, cellular physiology and biochemistry, synaptic and neural plasticity, and behavioral models, and is unique in covering epigenetically based disorders of the central nervous system.Behavioral epigenetics is the study of how environmental factors alter behavior, addressing the fundamental mechanisms that shape development and individual vulnerability/resili... to adverse behavioral outcomes. By understanding the molecular mechanisms involved in epigenetic modulation, researchers may be able to develop targeted therapies for those individuals in whom it malfunctions.Edited by the most highly regarded leaders in the field, this book offers a comprehensive review of behavioral epigenetics and a balanced treatment of the strengths and weaknesses in experimentation in this area. Covering background material as well as topics of current interest, it serves both as a cutting-edge resource and a foundational reference. The book will benefit neuroscience researchers and graduate students with an interest in the links between gene regulation and behavior, as will clinicians dealing with disorders such as addiction, depression, and schizophrenia.

  • International Review of Cell and Molecular Biology

    • 1st Edition
    • Volume 300
    • Kwang W. Jeon
    • English
    International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Impact factor for 2011: 4.481.

  • Gametogenesis

    • 1st Edition
    • Volume 102
    • English
    This new volume of Current Topics in Developmental Biology covers the area of gametogenesis, with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as germline stem cells, signaling modalities during oogenesis in mammals, and genomic imprinting as a parental effect established in mammalian germ cells.

  • Seldin and Giebisch's The Kidney

    Physiology and Pathophysiology
    • 5th Edition
    • Robert J. Alpern + 2 more
    • English
    A classic nephrology reference for over 25years, Seldin and Giebisch’s The Kidney, is the acknowledged authority on renal physiology and pathophysiology. In this 5th edition, such new and powerful disciplines as genetics and cell biology have been deployed to deepen and widen further the explanatory framework. Not only have previous chapters been extensively updated, but new chapters have been added to incorporate additional disciplines. Individual chapters, for example, now provide detailed treatment of the significance of cilia; the role of stem cells is now given special consideration. Finally, there has been a significant expansion of the section of pathophysiology, incorporating the newer findings of cell biology and genetics. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin and Giebisch’s The Kidney is your number one source for information.

  • Fluorescence Fluctuation Spectroscopy (FFS) Part B

    • 1st Edition
    • Volume 519
    • English
    This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers fluorescence fluctuation spectroscopy and includes chapters on such topics as Förster resonance energy transfer (fret) with fluctuation algorithms, protein corona on nanoparticles by FCS, and FFS approaches to the study of receptors in live cells.

  • Plastic Films in Food Packaging

    Materials, Technology and Applications
    • 1st Edition
    • Sina Ebnesajjad
    • English
    The value of the groceries purchases in the USA is over $500 billion annually, most of which is accounted for by packaged foods. Plastic packaging of foods is not only ubiquitous in developed economies, but increasingly commonplace in the developing world, where plastic packaging is instrumental in decreasing the proportion of the food supply lost to spoilage. This new handbook is a combination of new material and updated chapters, chosen by Dr. Sina Ebnesajjad, from recently published books on this subject. Plastic Films in Food Packaging offers a practical handbook for engineers, scientists and managers working in the food packaging industry, providing a tailor-made package of science and engineering fundamentals, best practice techniques and guidance on new and emerging technologies. By covering materials, design, packaging processes, machinery and waste management together in one book, the authors enable the reader to take a lifecycle approach to food packaging. The Handbook addresses questions related to film grades, types of packages for different types of foods, packaging technologies, machinery and waste management. Additionally the book provides a review of new and emerging technologies. Two chapters cover the development of barrier films for food packaging and the regulatory and safety aspects of food packaging.

  • Encyclopedia of Human Nutrition

    • 3rd Edition
    • English
    The role of nutrition in improving quality of life and combating disease is undeniable — and researchers from different disciplines are bringing their perspectives to bear on this fundamental topic. The 4-volume Encyclopedia of Human Nutrition, Third Edition, is a thorough revision of the previous award-winning version and reflects the scientific advances in the field of human nutrition. It presents the latest understanding on a wide range of nutrition-related topics including food safety, weight management, vitamins, bioengineering of foods, plant based diet and raw foods among others. New articles on organic food, biofortification, nutritional labeling and the effect of religious customs on diet, among many others, reflect the dedication to currency in this revision. It not only contains the most current and thorough information available on the topic, but also contains broader cross-referencing on emerging opportunities for potential treatment and prevention of diseases.An ideal starting point for scientific research, Encyclopedia of Human Nutrition, Third Edition, continues to provide authoritative information in an accessible format, making this complex discipline available to readers at both the professional and non-professional level.

  • Genomics of Cyanobacteria

    • 1st Edition
    • Volume 65
    • English
    Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences. The series features a wide range of reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. This thematic volume features reviews on The Genomics of Cyanobacteria.

  • Insulin Therapy, An Issue of Endocrinology and Metabolism Clinics

    • 1st Edition
    • Volume 41-1
    • John L. Leahy + 1 more
    • English
    This issue of Endocrinology Clinics brings the reader up do date on the current standards and important advances in insulin therapy. The following clinical topics are discussed: types of insulins, including new insulins; goals of therapy; pathophysiology of, and insulin treatment in type1 and type 2 diabetes mellitus; pumps and glucose sensors; alternative insulin delivery; patient and provider insulin resistance; inpatient insulin therapy; insulin therapy in pregnancy; and pediatric insulin therapy.

  • Atlas of Hematopathology

    Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches
    • 1st Edition
    • Faramarz Naeim
    • English
    As the definitive diagnostic atlas of the diseases of the hematopoietic system, the Atlas of Hematopathology appeals to a wide range of people who are being trained in a variety of medical fields or practicing as non-hematopathologis... and therefore, are looking for a book which can provide information in a clear, focused format, with no excessive text or details. The atlas offers effective guidance in evaluating specimens from the lymph nodes, bone marrow, spleen, and peripheral blood, enabling clinicians to deliver more accurate and actionable pathology reports. Practicing physicians and those in pathology and hematology training also gain a better understanding of the nature of hematologic disorders and improve their diagnostic skills along the way. Taking a unique multi-disciplinary approach, the book covers conventional histopathology and cytopathology, as well as all important complementary diagnostic tests, such as immunophenotyping (immunohistochemical stains and flow cytometry), karyotyping, FISH and DNA/molecular studies. It offers concise textual and extensive visual coverage of both neoplastic and non-neoplastic hematology disorders, with the neoplastic hematology sections presented according to the most recent WHO classifications. There is also an introduction to the normal structures of hematopoietic tissues and the various multidisciplinary techniques. The atlas contains more than 900 high-quality color images that mirror the findings that fellows and clinicians encounter in practice. It provides information in a quick, simple and user-friendly manner, attracting those who are in training or are not considered experts in the field. Residents, fellows, practicing clinicians, and researchers in pathology, hematology, hematology/oncology, as well as graduate students in pathology and other clinicians workings in clinical hematology laboratories will all find it useful.

  • The Epidemiology of Plasmodium Vivax: History, Hiatus and Hubris

    • 1st Edition
    • Volume 80
    • English
    First published in 1963, Advances in Parasitology contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology. Advances in Parasitology includes medical studies on parasites of major influence, such as Plasmodium falciparum and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications. Eclectic volumes are supplemented by thematic volumes on various topics, including control of human parasitic diseases and global mapping of infectious diseases. The 2010 impact factor is1.683.

  • Nutritional Management of Renal Disease

    • 3rd Edition
    • Joel D. Kopple + 2 more
    • English
    This translational text offers in-depth reviews of the metabolic and nutritional disorders that are prevalent in patients with renal disease. Chapter topics address the growing epidemic of obesity and metabolic syndrome. Each chapter integrates basic and clinical approaches, from cell biology and genetics to diagnosis, patient management and treatment. Chapters in sections 4-7 include new illustrative case reports, and all chapters emphasize key concepts with chapter-ending summaries. New features also include the latest National Kidney Foundation Clinical Practice Guidelines on Nutrition in Chronic Renal Failure, the most recent scientific discoveries and the latest techniques for assessing nutritional status in renal disease, and literature reviews on patients who receive continuous veno-venous hemofiltration with or without dialysis.

  • NMR Metabolomics in Cancer Research

    • 1st Edition
    • Miroslava Čuperlović-Culf
    • English
    The application of nuclear magnetic resonance (NMR) metabolomics in cancer research requires an understanding of the many possibilities that NMR metabolomics can offer, as well as of the specific characteristics of the cancer metabolic phenotype and the open questions in cancer research. NMR metabolomics in cancer research presents a detailed account of the NMR spectroscopy methods applied to metabolomics mixture analysis along with a discussion of their advantages and disadvantages. Following an overview of the potential use of NMR metabolomics in cancer research, the book begins with an examination of the cancer metabolic phenotype and experimental methodology, before moving on to cover data pre-processing and data analysis. Chapters in the latter part of the book look at dynamic metabolic profiling, biomarker discovery, and the application of NMR metabolomics for different types of cancer, before a concluding chapter discusses future perspectives in the field.

  • Nutrigenetics

    Applying the Science of Personal Nutrition
    • 1st Edition
    • Martin Kohlmeier
    • English
    Nutrigenetics: Applying the Science of Personal Nutrition provides a fully referenced, readable guide to understanding the rationale and importance of nutrigenetic applications and explains why single nutrition recommendations will not fit everybody or even a majority of modern humans. This books explains how genetic variation shapes individual nutrition requirements and sensitivities, presents questions to ask about reported gene-nutrient interactions, and what needs to be done before putting nutrigenetic tests to practical use. This book blends key concepts from the fields of genetics, biochemistry, epidemiology, public health, and clinical medicine to give a rich perspective on the genetically diverse nutritional needs and sensitivities of individuals in health and disease. A steadily increasing number of people order genetic tests to find out what they should eat for better health, well being and performance, and an even greater number asks their healthcare providers about such tests. Most of the currently offered tests are not grounded in current knowledge, often absurdly so, but few professionals can explain why they are misguided. On the other hand, there are more evidence-supported genetic variants that can guide nutrition decisions, but again most healthcare providers know little about them, much less use them in their daily practice. There is a great need for a solidly evidence-based yet accessible book that explains the science of nutrigenetics and provides the tools to evaluate new nutrigenetic tests.

  • Side Effects of Drugs Annual

    A worldwide yearly survey of new data in adverse drug reactions
    • 1st Edition
    • Volume 34
    • Jeffrey K Aronson
    • English
    The Side Effects of Drugs Annual was first published in 1977. It has been continually published since then as a yearly update to the voluminous encyclopedia, Meyler's Side Effects of Drugs. Each new Annual continues to provide clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of adverse drug reactions and interactions. An international team of specialists has contributed to the informative Annual by critically interpreting it and by pointing to whatever is misleading.

  • Microfluidic Cell Culture Systems

    • 1st Edition
    • Christopher Bettinger + 2 more
    • English
    The fields of microfluidics and BioMEMS are significantly impacting cell biology research and applications through the application of engineering solutions to human disease and health problems. The dimensions of microfluidic channels are well suited to the physical scale of biological cells, and the many advantages of microfluidics make it an attractive platform for new techniques in biology. This new professional reference applies the techniques of microsystems to cell culture applications. The authors provide a thoroughly practical guide to the principles of microfluidic device design and operation and their application to cell culture techniques. The resulting book is crammed with strategies and techniques that can be immediately deployed in the lab. Equally, the insights into cell culture applications will provide those involved in traditional microfluidics and BioMEMS with an understanding of the specific demands and opportunities presented by biological applications. The goal is to guide new and interested researchers and technology developers to the important areas and state-of-the-practic... strategies that will enhance the efficiency and value of their technologies, devices and biomedical products.

  • Functional Neural Transplantation III

    Primary and Stem Cell Therapies for Brain Repair, Part II
    • 1st Edition
    • Volume 201
    • English
    This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on Functional Neural Transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

  • Axon Growth and Regeneration: Part 2

    • 1st Edition
    • Volume 106
    • English
    Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research. Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered. All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

  • Axon Growth and Regeneration: Part 1

    • 1st Edition
    • Volume 105
    • English
    Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding Axon Growth and Regeneration.

  • Emerging Horizons in Neuromodulation

    New Frontiers in Brain and Spine Stimulation
    • 1st Edition
    • Volume 107
    • English
    This issue of International Review of Neurobiology brings together cutting-edge research on neuromodulation. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery.

  • Agricultural Sustainability

    Progress and Prospects in Crop Research
    • 1st Edition
    • Gurbir Bhullar + 1 more
    • English
    Collaboratively written by top international experts and established scientists in various fields of agricultural research, this book focuses on the state of food production and sustainability; the problems with degradation of valuable sources of land, water, and air and their effects on food crops; the increasing demand of food resources; and the challenges of food security worldwide. The book provides cutting edge scientific tools and methods of research as well as solid background information that is accessible for those who have a strong interest in agricultural research and development and want to learn more on the challenges facing the global agricultural production systems.

  • Head and Neck Cancer, An Issue of Neuroimaging Clinics

    • 1st Edition
    • Volume 23-1
    • Patricia A. Hudgins + 1 more
    • English
    This issue reviews the state of the art in imaging head and neck cancer. Articles cover topics on Rationale for Staging by Imaging; Oral Cavity Cancer; Oropharynx; Nasopharyngeal Carcinoma; Pitfalls in Staging Squamous Cell Carcinoma of the Hypopharynx; Larynx; Major Salivary Glands; Thyroid Cancer; Lymph Nodes; Image-Guided Tissue Sampling; and Surgical Perspective.

  • Functional Neural Transplantation III

    Primary and Stem Cell Therapies for Brain Repair, Part I
    • 1st Edition
    • Volume 200
    • English
    This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on functional neural transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

  • Co-Transport Systems

    • 1st Edition
    • Volume 70
    • English
    Current Topics in Membranes is targeted towards scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. In this volume, researchers are encouraged to fully explore topics and research related to co-transport systems. The authors and editors associated with the Current Topics in Membranes series are recognized as world-renowned scientists in their respective fields, making CTM one of the premier serials on membranes.

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