
Modification of Lipid Metabolism
- 1st Edition - January 1, 1975
- Imprint: Academic Press
- Editor: Edward G. Perkins
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 5 5 1 1 5 0 - 6
- Paperback ISBN:9 7 8 - 0 - 1 2 - 4 3 3 5 3 9 - 4
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 1 5 8 5 2 - 7
Modification of Lipid Metabolism is a collection of proceedings presented at the Symposium on Modification of Lipid Metabolism, held during the American Chemical Society meeting in… Read more

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Request a sales quoteModification of Lipid Metabolism is a collection of proceedings presented at the Symposium on Modification of Lipid Metabolism, held during the American Chemical Society meeting in Atlantic City, New Jersey, on September 10-11, 1974. The symposium provided a forum for discussing advances in the modification of lipid metabolism and tackled topics ranging from the effect of dietary rapeseed oil on cardiac tissue to inborn errors of lipid metabolism and lysosomal storage disorders. Comprised of 10 chapters, this book begins with an overview of advances in the composition, structure, and functions of lipids in metabolic pathways, followed by a discussion on the effect of dietary rapeseed oil on cardiac tissue. The reader is then introduced to genetic lipid storage diseases, along with their diagnosis and treatment. Viral modification of cell surface glycosphingolipids as an important factor in contact inhibition of cell growth and division is also examined. Subsequent chapters deal with different approaches to the problem of obesity, dietary regulation of lipid storage and the use of a metabolic inhibitor to reduce lipid storage; the importance of perinatal nutrition; factors in the environment that may effect tissue lipids and their metabolism; and phase transitions in membranes and the effect of temperature changes on changes in lipids and proteins of membranes. This monograph should be of interest to practitioners in the fields of biology, biochemistry, and food science and nutrition.
List of Contributors
Preface
Recent Developments in Lipid Biosynthetic Pathways
I. Introduction
II. Phospholipids
III. Sphingomyelin
IV. Bacterial Pathways
V. Glyceryl Ethers
VI. Glycolipids
VII. Small Glycolipids
VIII. Complex Carbohydrates Containing Lipid
IX. Polyisoprenols
X. Fatty Acids
XI. Unsaturated Fatty Acid Biosynthesis
XII. Fatty Acid Elongation and Hydroxylation
XIII. Vitamin Ε
References
The Effect of Dietary Rapeseed Oil on Cardiac Tissue
I. Introduction
II. Early Lipidosis
III. Fate of Erucic Acid
IV. Necrosis and Fibrosis
References
Inborn Errors of Lipid Metabolism and Lysosomal Storage Disorders
I. Introduction
II. Lysosomes and Cellular Turnover
III. Primary Lysosomal Disorders
IV. Secondary Lysosomal Disorders
V. Diagnosis
VI. Treatment of Lysosomal Disorders
Summary
Acknowledgments
References
Intervention in Sphingolipid Metabolism with Synthetic Inhibitors
I. Text
Summary
References
Modification of Membrane Glycolipids by Oncogenic Agents
I. Introduction
II. Ganglioside Metabolism in Normal and Transformed Mouse Cells
III. Modulation of Transformation and Ganglioside Biosynthesis
IV. Molecular Basis for Altered Ganglioside Biosynthesis
Summary
References
Dietary Regulation of Lipid Metabolism
I. Introduction
II. Dietary Fat
III. Dietary Protein
IV. Dietary Carbohydrate and Meal Pattern
V. Dietary Butanediol
VI. Conclusions
Acknowledgments
References
Effect of (-)-Hydroxycitrate on Lipid Metabolism
I. Introduction
II. Stereoisomers of Hydroxycitrate
III. Effects on Lipid Biosynthesis
IV. Effects of (-)-Hydroxycitrate on Lipid Accumulation
Summary
Acknowledgments
References
Early Nutritional Influences on Development
I. Introduction
II. Human Studies: Adipose Cellularity and Weight Reduction
III. Animal Studies: Normal Development
IV. Animal Studies: 3Η-Thymidine In Vivo Injections
V. Animal Studies: Genetically Obese Zucker Rats
VI. Brain Development: Normal Growth
VII. Brain Development: Effect of Early Malnutrition 191
Summary
Acknowledgments
References
The Influence of Environmental Factors on Lipid Metabolism
I. Text
References
The Effect of Temperature Changes on Lipids and Proteins of Biological Membranes
Summary
I. Introduction
II. Liquid to Solid Phase Transitions
III. Freeze-Fracture Electron Microscopy and Phase Transitions
IV. Alteration of Phase Transitions
V. Critical Viscosity or Critical Volume Transition
VI. Role of Cholesterol in Lipid Phase Transitions of Animal Cell Membranes
VII. Protein Conformational Changes
VIII. Cold Adaptation and Hibernation
Acknowledgments
References
Subject Index
- Edition: 1
- Published: January 1, 1975
- No. of pages (eBook): 268
- Imprint: Academic Press
- Language: English
- Hardback ISBN: 9780125511506
- Paperback ISBN: 9780124335394
- eBook ISBN: 9780323158527
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