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Elsevier

Books in Life sciences

  • Mesenchymal Stem Cells in Cancer Therapy

    • 1st Edition
    • Khalid Shah
    • English
    With the thorough understanding of stem cell biology and the advent of targeted therapeutics for cancer, stem cell-based therapeutic strategies are being increasingly explored for the treatment of various cancer types. Mesenchymal Stem Cells in Cancer Therapy sheds light on current stem cell based targeted therapies for cancer, by focusing on the application of mesenchymal stem cells (MSC) in various cancers with emphasis on a number of aspects that are critical to the success of future stem cell based therapies for cancer. Sections of this publication are devoted to developing stem cell based therapies for cancer with the main focus on tumoritrophic properties of stem cells, engineering targeted therapeutics, utilization of imaging techniques and the recent combination studies utilizing currently employed therapeutics with stem cells. Mesenchymal Stem Cells in Cancer Therapy informs readers about critical and cutting edge stem cell therapies for cancer and also enables them to appreciate the vast plain of unresolved questions in stem cell research for cancer therapeutics.

  • Genomes of Herbaceous Land Plants

    • 1st Edition
    • Volume 69
    • English
    Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences. Currently in its 69th volume, the series features several reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. This thematic volume features reviews on genomes of herbaceous land plants

  • Advances in Agronomy

    • 1st Edition
    • Volume 123
    • English
    Advances in Agronomy continues to be recognized as a leading reference and a first-rate source for the latest research in agronomy. As always, the subjects covered are varied and exemplary of the myriad of subject matter dealt with by this long-running serial.

  • Equitable Solutions for Retaining a Robust STEM Workforce

    Beyond Best Practices
    • 1st Edition
    • Donna J. Dean + 1 more
    • English
    Equitable Solutions for Retaining a Robust STEM Workforce offers strategies and proven recommendations to accommodate work/life satisfaction for those in the STEM fields. Using real-life case studies, this book discusses universal issues such as dual careers and strategic decision making, childcare/dependent care in professional contexts, promoting family-friendly policies, as well as mentoring and networking. Equitable Solutions for Retaining a Robust STEM Workforce provides data and tools to drive successful programs relaying proactive solutions that STEM employers, academic institutions, policy-makers, and individuals can utilize.

  • Handbook of Nanosafety

    Measurement, Exposure and Toxicology
    • 1st Edition
    • Ulla Vogel + 5 more
    • English
    Handbook of Nanosafety: Measurement, Exposure and Toxicology, written by leading international experts in nanosafety, provides a comprehensive understanding of engineered nanomaterials (ENM), current international nanosafety regulation, and how ENM can be safely handled in the workplace. Increasingly, the importance of safety needs to be considered when promoting the use of novel technologies like ENM. With its use of case studies and exposure scenarios, Handbook of Nanosafety demonstrates techniques to assess exposure and risks and how these assessments can be applied to improve workers' safety. Topics covered include the effects of ENM on human health, characterization of ENM, aerosol dynamics and measurement, exposure and risk assessment, and safe handling of ENM. Based on outcomes from the NANODEVICE initiative, this is an essential resource for those who need to apply current nanotoxicological thinking in the workplace and anyone who advises on nanosafety, such as professionals in toxicology, occupational safety and risk assessment.

  • Endosome Signaling Part A

    • 1st Edition
    • Volume 534
    • English
    This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This is the first of two volumes on endosome signaling and includes chapters on such topics as measurement of entry into the endosomal compartment by multi-parametric image analysis, assessment of peptide internalization and endosomal signaling, and VEGF-A in endosomal signaling.

  • The Flagellar World

    Electron Microscopic Images of Bacterial Flagella and Related Surface Structures
    • 1st Edition
    • Shin-Ichi Aizawa
    • English
    The Flagellar World is a unique publication. The product of years of research and data collection by the author, this book is a pictorial guide to flagella in a variety of organisms. Each EM image is accompanied by a short description of the system in each organism. These never-before-seen pictures represent a wide variety of flagella, including Legionella pneumophila, Escherichia coli, Pseudomonas aeruginosa, and many others. Researchers in microbiology, immunology, and parasitology will find this a fascinating and useful resource.

  • Corn and Grain Sorghum Comparison

    All Things Considered
    • 1st Edition
    • Yared Assefa + 5 more
    • English
    Corn and grain sorghum (Sorghum bicolor subsp. bicolor L) are among the top cereal crops world wide, and both are key for global food security. Similarities between the two crops, particularly their adaptation for warm-season grain production, pose an opportunity for comparisons to inform appropriate cropping decisions. This book provides a comprehensive review of the similarities and differences between corn and grain sorghum. It compares corn and sorghum crops in areas such as morphology, physiology, phenology, yield, resource use and efficiency, and impact of both crops in different cropping systems. Producers, researchers and extension agents in search of reliable scientific information will find this in-depth comparison of crops with potential fit in dryland and irrigations cropping systems particularly valuable.

  • Light and Video Microscopy

    • 2nd Edition
    • Randy O. Wayne
    • English
    The purpose of this book is to provide the most comprehensive, easy-to-use, and informative guide on light microscopy. Light and Video Microscopy will prepare the reader for the accurate interpretation of an image and understanding of the living cell. With the presentation of geometrical optics, it will assist the reader in understanding image formation and light movement within the microscope. It also provides an explanation of the basic modes of light microscopy and the components of modern electronic imaging systems and guides the reader in determining the physicochemical information of living and developing cells, which influence interpretation.

  • Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases

    • 1st Edition
    • Christophe Wiart
    • English
    Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases is the second volume in the series, Pharmaceutical Leads from Medicinal Plants. This book includes key pharmacological and chemical evidence to support the selection of promising pre-clinical candidates for the treatment of neurodegenerative diseases. This important addition to the natural product and drug discovery literature contains the history, synonyms, medicinal uses, phytopharmacology, pre-clinical potential, and rationale for each plant selected. By providing critical evaluation of pharmacological data, mechanisms of action, and structural requirements for the development of future neuroprotective agents, this comprehensive reference is a beneficial resource for industry and academic scientists whose research focuses on neurodegenerative drug discovery and development.

  • Hygiene in Food Processing

    Principles and Practice
    • 2nd Edition
    • H.L.M. Lelieveld + 2 more
    • English
    The hygienic processing of food concerns both potential hazards in food products and the regulation, design, and management of food processing facilities. This second edition of Hygiene in Food Processing gives a revised overview of the practices for safe processing and incorporates additional chapters concerning pest control, microbiological environmental sampling, and the economics of food plants. Part one addresses microbial risks in foods and the corresponding regulation in the European Union. Part two discusses the hygienic design of food factory infrastructure, encompassing the design and materials for the factory itself, as well as food processing equipment. This edition includes a new chapter on the control of compressed gases used to pneumatically operate equipment. Part three focuses on cleaning and disinfection practices in food processing. The chapter on cleaning in place also considers more cost-effective systems, and complements the additional chapter on maintenance of equipment. These chapters also explore issues such as the hygiene of workers, potential infection by foreign bodies, and pest control. Further, the chapter on microbiological sampling explains how to calculate the risk of contamination depending on the product's environment. This essential second edition is useful to professionals responsible for hygiene in the food industry. It provides a comprehensive, yet concise and practical reference source for food plant managers, suppliers of food processing equipment, building contractors, and food inspectors looking for an authoritative introduction to hygiene regulation, hygienic design, and sanitation.

  • Encyclopedia of Food Safety

    • 1st Edition
    • Yasmine Motarjemi
    • English
    With the world’s growing population, the provision of a safe, nutritious and wholesome food supply for all has become a major challenge. To achieve this, effective risk management based on sound science and unbiased information is required by all stakeholders, including the food industry, governments and consumers themselves. In addition, the globalization of the food supply requires the harmonization of policies and standards based on a common understanding of food safety among authorities in countries around the world. With some 280 chapters, the Encyclopedia of Food Safety provides unbiased and concise overviews which form in total a comprehensive coverage of a broad range of food safety topics, which may be grouped under the following general categories: History and basic sciences that support food safety; Foodborne diseases, including surveillance and investigation; Foodborne hazards, including microbiological and chemical agents; Substances added to food, both directly and indirectly; Food technologies, including the latest developments; Food commodities, including their potential hazards and controls; Food safety management systems, including their elements and the roles of stakeholders. The Encyclopedia provides a platform for experts from the field of food safety and related fields, such as nutrition, food science and technology and environment to share and learn from state-of-the art expertise with the rest of the food safety community.

  • Literature, Neurology, and Neuroscience: Neurological and Psychiatric Disorders

    • 1st Edition
    • Volume 206
    • English
    This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume on the neurosciences, neurology, and literature vividly shows how science and the humanities can come together --- and have come together in the past. Its sections provide a new, broad look at these interactions, which have received surprisingly little attention in the past. Experts in the field cover literature as a window to neurological and scientific zeitgeists, theories of brain and mind in literature, famous authors and their suspected neurological disorders, and how neurological disorders and treatments have been described in literature. In addition, a myriad of other topics are covered, including some on famous authors whose important connections to the neurosciences have been overlooked (e.g., Roget, of Thesaurus fame), famous neuroscientists who should also be associated with literature, and some overlooked scientific and medical men who helped others produce great literary works (e,g., Bram Stoker's Dracula). There has not been a volume with this coverage in the past, and the connections it provides should prove fascinating to individuals in science, medicine, history, literature, and various other disciplines.

  • Extracellular Glycolipids of Yeasts

    Biodiversity, Biochemistry, and Prospects
    • 1st Edition
    • Ekaterina Kulakovskaya + 1 more
    • English
    Extracellular Glycolipids of Yeasts: Biodiversity, Biochemistry, and Prospects provides a comprehensive view of the biochemistry, biological activity, and practical application of extracellular glycolipids of yeast. This book brings much-needed clarity to the complex topic of glycolipids and streamlines the rather confusing terminology used for glycolipids. It also provides a wealth of modern data on their composition, structure and properties, biosynthetic pathways, methods of isolation and identification, antifungal activity, and mechanisms of action. Studies of extracellular glycolipids of yeast now draw the attention of researchers in life science and biotechnology due to numerous recently revealed biological properties of these compounds. These compounds are scientifically and practically promising in medicine and agriculture due to their biosurfactant and fungicidal properties, as well as a number of other biological activities. Extracellular Glycolipids of Yeasts gives researchers studying biochemistry of microorganisms and related biologically active compounds a much-needed guide to the basic data that will aid in these increasingly generative pursuits.

  • New Functional Biomaterials for Medicine and Healthcare

    • 1st Edition
    • Elena P. Ivanova + 2 more
    • English
    New Functional Biomaterials for Medicine and Healthcare provides a concise summary of the latest developments in key types of biomaterials. The book begins with an overview of the use of biomaterials in contemporary healthcare and the process of developing novel biomaterials; the key issues and challenges associated with the design of complex implantable systems are also highlighted. The book then reviews the main materials used in functional biomaterials, particularly their properties and applications. Individual chapters focus on both natural and synthetic polymers, metallic biomaterials, and bio-inert and bioactive ceramics. Advances in processing technologies and our understanding of materials and their properties have made it possible for scientists and engineers to develop more sophisticated biomaterials with more targeted functionality. New Functional Biomaterials for Medicine and Healthcare provides an ideal one-volume summary of this important field that represents essential reading for scientists, engineers, and clinicians, and a useful reference text for undergraduate and postgraduate students.

  • Global Safety of Fresh Produce

    A Handbook of Best Practice, Innovative Commercial Solutions and Case Studies
    • 1st Edition
    • Jeffrey Hoorfar
    • English
    Continuing food poisoning outbreaks around the globe have put fresh produce safety at the forefront of food research. Global Safety of Fresh Produce provides a detailed and comprehensive overview of best practice for produce safety throughout the food chain, and unique coverage of commercial technologies for fresh produce safety. Part one covers the production and regulation of fresh produce on the agricultural level, including issues of niche farm fresh products, FDA regulation, and zoonotic transfer of pathogens from animals to farm products. Part two moves on to look at safety and environmental issues surrounding fresh produce processing, such as postharvest washing, alternative sanitizers, and using produce waste as animal feed. Part three focuses on current and emerging commercial solutions for fresh produce safety, like ionizing radiation and edible coatings, and part four covers methods of laboratory testing and related legislation. The final section of the book covers a series of case studies of fresh produce safety breaches, including European E. coli outbreaks in sprouts and leafy greens, and the illegal use of fluorescent whitening agents (FWAs) in China. This book is an essential text for R&D managers in the fresh produce industry, quality control professionals working with fresh produce throughout the food chain, postgraduate students, and academic researchers with an interest in fresh produce safety.

  • The Guide to Investigation of Mouse Pregnancy

    • 1st Edition
    • B. Anne Croy + 3 more
    • English
    The Guide to Investigation of Mouse Pregnancy is the first publication to cover the mouse placenta or the angiogenic tree the mother develops to support the placenta. This much-needed resource covers monitoring of the cardiovascular system, gestational programming of chronic adult disease, epigenetic regulation, gene imprinting, and stem cells. Offering detailed and integrated information on how drugs, biologics, stress, and manipulations impact pregnancy in the mouse model, this reference highlights techniques used to analyze mouse pregnancy. Joining the ranks of much referenced mouse resources, The Guide to Investigation of Mouse Pregnancy is the only manual providing needed content on pregnancy in animal models for translational medicine and research.

  • Social Predation

    How Group Living Benefits Predators and Prey
    • 1st Edition
    • Guy Beauchamp
    • English
    The classic literature on predation dealt almost exclusively with solitary predators and their prey. Going back to Lotka-Volterra and optimal foraging theory, the theory about predation, including predator-prey population dynamics, was developed for solitary species. Various consequences of sociality for predators have been considered only recently. Similarly, while it was long recognized that prey species can benefit from living in groups, research on the adaptive value of sociality for prey species mostly emerged in the 1970s. The main theme of this book is the various ways that predators and prey may benefit from living in groups. The first part focusses on predators and explores how group membership influences predation success rate, from searching to subduing prey. The second part focusses on how prey in groups can detect and escape predators. The final section explores group size and composition and how individuals respond over evolutionary times to the challenges posed by chasing or being chased by animals in groups. This book will help the reader understand current issues in social predation theory and provide a synthesis of the literature across a broad range of animal taxa.

  • Plant Virus-Host Interaction

    Molecular Approaches and Viral Evolution
    • 1st Edition
    • R.K. Gaur + 2 more
    • English
    Plant Virus-Host Interaction contains cutting-edge research in plant molecular virology, including pathogenic viroids and transport by insect vectors, interference with transmission to control viruses, and synergism, with pivotal coverage of RNA silencing and the counter-defensive strategies used by viruses to overcome the silencing response in plants. With a clear focus on plant virus evolution, including quantitative and population genetics, Plant Virus-Host Interaction provides insights on the major factors favoring disease emergence, such as genetic change in pathogen and host populations and changes in host ecology and environment. The book also examines socioeconomic implications of widespread plant viral agents. Contributions from leading experts around the globe provide varied perspectives, while comprehensive coverage ensures a complete look at this exciting field.

  • Handbook of Polymer Applications in Medicine and Medical Devices

    • 1st Edition
    • Kayvon Modjarrad + 1 more
    • English
    While the prevalence of plastics and elastomers in medical devices is now quite well known, there is less information available covering the use of medical devices and the applications of polymers beyond medical devices, such as in hydrogels, biopolymers and silicones beyond enhancement applications, and few books in which these are combined into a single reference. This book is a comprehensive reference source, bringing together a number of key medical polymer topics in one place for a broad audience of engineers and scientists, especially those currently developing new medical devices or seeking more information about current and future applications. In addition to a broad range of applications, the book also covers clinical outcomes and complications arising from the use of the polymers in the body, giving engineers a vital insight into the real world implications of the devices they’re creating. Regulatory issues are also covered in detail. The book also presents the latest developments on the use of polymers in medicine and development of nano-scale devices.

  • International Cooperation, Convergence and Harmonization of Pharmaceutical Regulations

    A Global Perspective
    • 1st Edition
    • Pierre-Louis Lezotre
    • English
    International Cooperation, Convergence and Harmonization of Pharmaceutical Regulations: A Global Perspective provides the current status of the complex and broad phenomenon of cooperation, convergence and harmonization in the pharmaceutical sector (Part I), thoroughly evaluates its added value and its critical parameters and influencing factors (Part II) in order to recommend actions and measures to support the next steps for cooperation, convergence and harmonization (Part III). All of these recommendations in the book support the establishment of a better coordinated global pharmaceutical system which represents the best realistic alternative to fulfill the objective to establish a global coalition of regulators and to respond to an increased demand to further cooperation in the pharmaceutical sector. This proposed framework, which leverages all of the ongoing positive cooperation initiatives and uses as foundations all of the numerous harmonization projects developed over the years, presents advantages for all stakeholders and would definitively have significant added value to the promotion and protection of global public health.

  • Diagnostic Ultrasound Imaging: Inside Out

    • 2nd Edition
    • Thomas L. Szabo
    • English
    Diagnostic Ultrasound Imaging provides a unified description of the physical principles of ultrasound imaging, signal processing, systems and measurements. This comprehensive reference is a core resource for both graduate students and engineers in medical ultrasound research and design. With continuing rapid technological development of ultrasound in medical diagnosis, it is a critical subject for biomedical engineers, clinical and healthcare engineers and practitioners, medical physicists, and related professionals in the fields of signal and image processing. The book contains 17 new and updated chapters covering the fundamentals and latest advances in the area, and includes four appendices, 450 figures (60 available in color on the companion website), and almost 1,500 references. In addition to the continual influx of readers entering the field of ultrasound worldwide who need the broad grounding in the core technologies of ultrasound, this book provides those already working in these areas with clear and comprehensive expositions of these key new topics as well as introductions to state-of-the-art innovations in this field.

  • Modelling Methodology for Physiology and Medicine

    • 2nd Edition
    • Ewart Carson + 1 more
    • English
    Modelling Methodology for Physiology and Medicine, Second Edition, offers a unique approach and an unprecedented range of coverage of the state-of-the-art, advanced modeling methodology that is widely applicable to physiology and medicine. The second edition, which is completely updated and expanded, opens with a clear and integrated treatment of advanced methodology for developing mathematical models of physiology and medical systems. Readers are then shown how to apply this methodology beneficially to real-world problems in physiology and medicine, such as circulation and respiration. The focus of Modelling Methodology for Physiology and Medicine, Second Edition, is the methodology that underpins good modeling practice. It builds upon the idea of an integrated methodology for the development and testing of mathematical models. It covers many specific areas of methodology in which important advances have taken place over recent years and illustrates the application of good methodological practice in key areas of physiology and medicine. It builds on work that the editors have carried out over the past 30 years, working in cooperation with leading practitioners in the field.

  • Catecholamine Research in the 21st Century

    Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012
    • 1st Edition
    • Lee E. Eiden
    • English
    Through the use of extended graphical abstracts and some traditional text-only abstracts this collection provides, a record of and roadmap to, the research presented at The Tenth International Catecholamine Symposium (XICS) held in September of 2012. Organized around ten general themes, each is introduced by a short overview identifying interesting research programs, results and potential areas of growth. The collection is a roadmap to key research and future opportunities for new catecholamine research programs and will be of interest to neuroscientists and clinical neurologists interested in understanding the current and future state of catecholamine research.

  • Green Vegetable Oil Processing

    Revsied First Edition
    • 1st Edition
    • Walter E. Farr + 1 more
    • English
    Alternative green food processing technologies have gained much technical and industrial attention in recent years as a potential means of reducing costs and promoting consumer awareness of corporate environmental responsibility. However, utilizing green principles is now becoming an effective business approach to enhance vegetable oil processing profitability. Two years have passed since the first edition of Green Vegetable Oil Processing was published. The Revised First Edition includes much of the content of the first edition, but incorporates updated data, details, images, figures, and captions. This book addresses alternative green technologies at various stages of oilseed and vegetable oil processing. This includes oil extraction technologies such as expeller, aqueous and supercritical methods, and green modifications of conventional unit operations such as degumming, refining, bleaching, hydrogenation, winterizing/dewaxing... fractionation, and deodorization. While most chapters describe soy oil processing, the techniques described equally applicable to oils and fats in general.

  • Fish Physiology: Organic Chemical Toxicology of Fishes

    • 1st Edition
    • Volume 33
    • Keith B. Tierney + 2 more
    • English
    Fish Physiology: Organic Chemical Toxicology of Fishes discusses the different types of organic chemical contaminants and their respective toxic effects in fish. The book also covers the detection of dissolved organic compounds and methods to assess organic toxicity. Substances addressed in this book include organometallics, hydrocarbons, endocrine disrupting compounds (EDCs), insecticides, herbicides, and pharmaceuticals. Fish are exposed to an ever-increasing array of organic chemicals that find their way into rivers and oceans. Some of these compounds are no longer being produced but nonetheless persist within the environment (persistent organic pollutants, or POPs). The exposure of fish to toxic organic compounds has potential impact on human, fish, and ecosystem health. Yet the regulations that govern environmental water quality vary worldwide, and compliance is never complete. This book provides a crucial resource on these issues for researchers in zoology, fish physiology, and related fields; applied researchers in environmental monitoring, conservation biology, and toxicology; and university-level students and instructors in these areas.

  • The Autoimmune Diseases

    • 5th Edition
    • M. Eric Gershwin + 1 more
    • English
    Since publication of the 4th Edition of The Autoimmune Diseases in 2006, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This fully revised 5th Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels and includes expanded coverage of autoinflammatory disease and autoimmune responses to tumors.

  • Cell Press Reviews: Stem Cells to Model and Treat Disease

    • 1st Edition
    • Cell Press
    • English
    Cell Press Reviews: Stem Cells to Model and Treat Disease informs, inspires, and connects stem cell researchers and clinicians at all stages in their careers with timely, comprehensive reviews written by leaders in the field and curated by Cell Press editors. The publication offers a broad view of some of the most compelling topics in stem cell research including: Safety and efficacy of stem cell treatments Stem-cell-based organ regeneration Integrating stem cells into personalized drug discovery Using pluripotent stem cells for treating neurological disease Engineering hematopoietic stem cells for innovative therapies Contributions come from leading voices in the field, including:- Shinya Yamanaka, Recipient of the 2012 Nobel Prize for Physiology or Medicine, Recipient of the 2012 Millennium Technology Prize, Professor and Director of the Center for iPS Cell Research and Application at Kyoto University, Senior Investigator at the Gladstone Institute of Cardiovascular Disease, L.K. Whittier Foundation Investigator in Stem Cell Biology and Professor at the University of California, San Francisco- George Q. Daley, Samuel E. Lux IV Professor of Hematology/Oncology at Harvard Medical School and Director for the Stem Cell Transplantation Program at Boston Children’s Hospital- Irving Weissman, Member of National Academy of Sciences, Virgina & D.K Ludwig Professor for Clinical Investigation in Cancer Research, and Director for Institute of Stem Cell Biology and Regenerative Medicine at Stanford University of Medicine Cell Press Reviews: Stem Cells to Model and Treat Disease is part of the Cell Press Reviews series, which features reviews published in Cell Press primary research and Trends reviews journals.

  • Molecular Sensors and Nanodevices

    Principles, Designs and Applications in Biomedical Engineering
    • 1st Edition
    • John X. J. Zhang + 1 more
    • English
    With applications ranging from medical diagnostics to environmental monitoring, molecular sensors (also known as biosensors, chemical sensors, or chemosensors), along with emerging nanotechnologies offer not only valuable tools but also unlimited possibilities for engineers and scientists to explore the world. New generation of functional microsystems can be designed to provide a variety of small scale sensing, imaging and manipulation techniques to the fundamental building blocks of materials. This book provides comprehensive coverage of the current and emerging technologies of molecular sensing, explaining the principles of molecular sensor design and assessing the sensor types currently available. Having explained the basic sensor structures and sensing principles, the authors proceed to explain the role of nano/micro fabrication techniques in molecular sensors, including MEMS, BioMEMS, MicroTAS among others. The miniaturization of versatile molecular sensors opens up a new design paradigm and a range of novel biotechnologies, which is illustrated through case studies of groundbreaking applications in the life sciences and elsewhere. As well as the techniques and devices themselves, the authors also cover the critical issues of implantability, biocompatibility and the regulatory framework. The book is aimed at a broad audience of engineering professionals, life scientists and students working in the multidisciplinary area of biomedical engineering. It explains essential principles of electrical, chemical, optical and mechanical engineering as well as biomedical science, intended for readers with a variety of scientific backgrounds. In addition, it will be valuable for medical professionals and researchers. An online tutorial developed by the authors provides learning reinforcement for students and professionals alike.

  • Changing Brains

    Applying Brain Plasticity to Advance and Recover Human Ability
    • 1st Edition
    • Volume 207
    • English
    This volume of Progress in Brain Research focuses on the applying brain plasticity to advance and recover human ability. The volume starts off discussing brain plasticity in the young, adults and old brains with follow on discussions regarding the type of neuroscience-based training that is on offer in impaired child populations as well as discussing the therapeutics involved in adults.

  • Clinical Chemistry, Immunology and Laboratory Quality Control

    A Comprehensive Review for Board Preparation, Certification and Clinical Practice
    • 1st Edition
    • Amitava Dasgupta + 1 more
    • English
    All pathology residents must have a good command of clinical chemistry, toxicology, immunology, and laboratory statistics to be successful pathologists, as well as to pass the American Board of Pathology examination. Clinical chemistry, however, is a topic in which many senior medical students and pathology residents face challenges. Clinical Chemistry, Immunology and Laboratory Quality Control meets this challenge head on with a clear and easy-to-read presentation of core topics and detailed case studies that illustrate the application of clinical chemistry knowledge to everyday patient care. This basic primer offers practical examples of how things function in the pathology clinic as well as useful lists, sample questions, and a bullet-point format ideal for quick pre-Board review. While larger textbooks in clinical chemistry provide highly detailed information regarding instrumentation and statistics, this may be too much information for students, residents, and clinicians. This book is designed to educate senior medical students, residents, and fellows, and to "refresh" the knowledge base of practicing clinicians on how tests are performed in their laboratories (i.e., method principles, interferences, and limitations).

  • Nanoparticles and the Immune System

    Safety and Effects
    • 1st Edition
    • Diana Boraschi + 1 more
    • English
    Nanoparticles and the Immune System provides a reference text for toxicologists, materials scientists and regulators and covers the key issues of interaction of nanomaterials with the immune system. The book discusses several issues that toxicologists and regulators need to know: identification of endpoints that are relevant for assessing hazard, evaluating impact on immunologically frail populations, and how to evaluate chronic/cumulative effects. In addition, the book addresses the possibility of turning the immunomodulating properties of certain nanomaterials to our advantage for amplifying immune responses in certain diseases or preventive strategies (e.g. vaccination).

  • Cleaning with Solvents: Science and Technology

    • 1st Edition
    • John Durkee
    • English
    High-precision cleaning is required across a wide range of sectors, including aerospace, defense, medical device manufacturing, pharmaceutical processing, semiconductor/electr... etc. Cleaning parts and surfaces with solvents is simple, effective and low-cost. Although health and safety and environmental concerns come into play with the use of solvents, this book explores how safe and compliant solvent-based cleaning techniques can be implemented. A key to this is the selection of the right solvent. The author also examines a range of newer "green" solvent cleaning options. This book supplies scientific fundamentals and practical guidance supported by real-world examples. Durkee explains the three principal methods of solvent selection: matching of solubility parameters, reduction of potential for smog formation, and matching of physical properties. He also provides guidance on the safe use of aerosols, wipe-cleaning techniques, solvent stabilization, economics, and many other topics. A compendium of blend rules is included, covering the physical, chemical, and environmental properties of solvents.

  • Cell Press Reviews: Core Concepts in Cell Biology

    • 1st Edition
    • Cell Press
    • English
    Written by leading cell biologists and curated by Cell Press editors, reviews in the Cell Press Reviews: Core Concepts in Cell Biology publication informs, inspires, and connects cell biologists at all stages in their careers with timely, comprehensive insight into the most recent exciting developments across cell biology and hot topics within core areas of the field including: Signaling mechanisms and membrane biology Cytoskeletal self-organization and cell polarity Organelle dynamics and biogenesis Morphogenesis and cell motility Chromatin and genome organization in nuclear function Contributions come from leading voices in cell biology, who are defining the future of their field, including:- Tom Misteli, National Cancer Institute - Galit Lahav, Harvard Medical School - Scott D. Emr, Cornell University - David G. Drubin, University of California, Berkeley - Tom Rapoport, Harvard Medical School - Anthony A. Hyman, Max Planck Institute of Molecular and Cell Biology, Dresden This publication is part of the Cell Press Reviews series, which features reviews published in Cell Press primary research and Trends reviews journals.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 62
    • English
    Volume 62 in the internationally acclaimed Advances in Clinical Chemistry contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists. The serial provides the latest and most up-to-date technologies related to the field of Clinical Chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Advances in Carbohydrate Chemistry and Biochemistry

    • 1st Edition
    • Volume 70
    • English
    Since its inception in 1945, this serial has provided critical and informative articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.

  • Neurobiology of Autism

    • 1st Edition
    • Volume 113
    • English
    This volume in the International Review of Neurobiology is a comprehensive overview of the state-of-the-art research into autism pathophysiology. Its chapters cover a wide range of etiologies, from genetics and development to environmental factors. In addition, it discusses key cell and behavioral phenotypes, including cortical and cerebellar phenotypes, as well as language and motor outputs. Finally, this volume's chapters on gene expression in the brain describe how genes may be connected to phenotypes in autism.

  • Endocrine Gland Development and Disease

    • 1st Edition
    • Volume 106
    • English
    This new volume of Current Topics in Developmental Biology covers endocrine gland development and disease, and with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as sex determination & gonadogenesis, hypothalamus, paraythyroid and placenta.

  • Advances in the Neurochemistry and Neuropharmacology of Tourette Syndrome

    • 1st Edition
    • Volume 112
    • English
    This volume of International Review of Neurobiology brings together cutting-edge research on advances in the neurochemistry and neuropharmacology of Tourette syndrome. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and includes important topics regards tics, neurotransmitters, pharmacology and emerging treatments.

  • Computational Systems Biology

    From Molecular Mechanisms to Disease
    • 2nd Edition
    • Andres Kriete + 1 more
    • English
    This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling.

  • Autoantibodies

    • 3rd Edition
    • Yehuda Shoenfeld + 2 more
    • English
    Autoimmune diseases are characterized by the occurrence of antibodies reacting with self-constituents of the body. The fully updated third edition of Autoantibodies is an in-depth review of the main autoantibodies identified up to now, with particular emphasis on those that display a diagnostic or prognostic clinical value. The new edition covers recent scientific advances, diagnostic techniques, and therapeutic technologies. Each chapter is focused on a single family of autoantibodies. This important reference contains historical notes, definitions, origins and sources of antigens recognized genetic associations, mediated pathogenic mechanisms, methods of detection, as well as clinical utility (disease prevalence and association, diagnostic value, sensitivity and specificity, prognostic value). This is an ideal reference for anyone involved in the field of autoimmune diseases.

  • Working with Dynamic Crop Models

    Methods, Tools and Examples for Agriculture and Environment
    • 2nd Edition
    • Daniel Wallach + 3 more
    • English
    This second edition of Working with Dynamic Crop Models is meant for self-learning by researchers or for use in graduate level courses devoted to methods for working with dynamic models in crop, agricultural, and related sciences. Each chapter focuses on a particular topic and includes an introduction, a detailed explanation of the available methods, applications of the methods to one or two simple models that are followed throughout the book, real-life examples of the methods from literature, and finally a section detailing implementation of the methods using the R programming language. The consistent use of R makes this book immediately and directly applicable to scientists seeking to develop models quickly and effectively, and the selected examples ensure broad appeal to scientists in various disciplines.

  • Literature, Neurology, and Neuroscience: Historical and Literary Connections

    • 1st Edition
    • Volume 205
    • English
    This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume on the neurosciences, neurology, and literature vividly shows how science and the humanities can come together --- and have come together in the past. Its sections provide a new, broad look at these interactions, which have received surprisingly little attention in the past. Experts in the field cover literature as a window to neurological and scientific zeitgeists, theories of brain and mind in literature, famous authors and their suspected neurological disorders, and how neurological disorders and treatments have been described in literature. In addition, a myriad of other topics are covered, including some on famous authors whose important connections to the neurosciences have been overlooked (e.g., Roget, of Thesaurus fame), famous neuroscientists who should also be associated with literature, and some overlooked scientific and medical men who helped others produce great literary works (e,g., Bram Stoker's Dracula). There has not been a volume with this coverage in the past, and the connections it provides should prove fascinating to individuals in science, medicine, history, literature, and various other disciplines.

  • Neural Crest Cells

    Evolution, Development and Disease
    • 1st Edition
    • Paul Trainor
    • English
    Neural Crest Cells: Evolution, Development and Disease summarizes discoveries of historical significance and provides in-depth, current analyses of the evolution of neural crest cells, their contribution to embryo development, and their roles in disease. In addition, prospects for tissue engineering, repair and regeneration are covered, offering a timely synthesis of the current knowledge in neural crest cell research. A comprehensive resource on neural crest cells for researchers studying cell biology, developmental biology, stem cells and neurobiology, Neural Crest Cells: Evolution, Development and Disease provides foundational information needed for students , practicing physicians and dentists treating patients with craniofacial defects.

  • Identification of Neural Markers Accompanying Memory

    • 1st Edition
    • Alfredo Meneses
    • English
    Identification of Neural Markers Accompanying Memory is a fresh and novel volume of memory study, providing up-to-date and comprehensive information for both students and researchers focused on the identification of neural markers accompanying memory. Contributions by experts in specific areas of memory study provide background on and definitions of memory, memory alterations, and the brain areas involved in memory and its related processes, such as consolidation, retrieval, forgetting, amnesia, and antiamnesiac effects. With coverage of the principal neurotransmitters related to memory, brain disorders presenting memory alterations, and available treatments—and with discussion of neural markers as new targets for the treatment of memory alterations—Identifi... of Neural Markers Accompanying Memory is a necessary and timely work for researchers in this growing field.

  • Ecological Networks in an Agricultural World

    • 1st Edition
    • Volume 49
    • English
    The theme of this volume is to discuss the Ecological Networks in an Agricultural World. The volume covers important topics such Networking Agroecology, Construction and Validation of Food-webs using Logic-based Machine Learning and Text-mining and Eco-evolutionary dynamics in agricultural networks.

  • Electrocardiography of Laboratory Animals

    • 1st Edition
    • Jeffrey W. Richig + 1 more
    • English
    Electrocardiography of Laboratory Animals is the only book covering electrocardiography of laboratory animals, including dogs, mini-pigs, and cynomologus monkeys. As more countries institute requirements for the care of laboratory animals in research, this publication offers an effective standard on performing and analyzing ECGs. Topics covered include safety electrocardiography, toxicology, safety pharmacology, and telemetry. Electrocardiography of Laboratory Animals will assist biological and medical researchers, veterinarians, zoologists, and students in understanding electrocardiography of various species of animals used in research.

  • Advances in Carbohydrate Chemistry and Biochemistry

    • 1st Edition
    • Volume 69
    • English
    Since its inception in 1945, this serial has provided critical and informative articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.

  • Cancer Genomics

    From Bench to Personalized Medicine
    • 1st Edition
    • Graham Dellaire + 2 more
    • English
    Cancer Genomics addresses how recent technological advances in genomics are shaping how we diagnose and treat cancer. Built on the historical context of cancer genetics over the past 30 years, the book provides a snapshot of the current issues and state-of-the-art technologies used in cancer genomics. Subsequent chapters highlight how these approaches have informed our understanding of hereditary cancer syndromes and the diagnosis, treatment and outcome in a variety of adult and pediatric solid tumors and hematologic malignancies. The dramatic increase in cancer genomics research and ever-increasing availability of genomic testing are not without significant ethical issues, which are addressed in the context of the return of research results and the legal considerations underlying the commercialization of genomic discoveries. Finally, the book concludes with "Future Directions", examining the next great challenges to face the field of cancer genomics, namely the contribution of non-coding RNAs to disease pathogenesis and the interaction of the human genome with the environment.

  • A Complete Guide to Quality in Small-Scale Wine Making

    • 1st Edition
    • John Anthony Considine + 1 more
    • English
    As the wine industry has experienced a period of rapid global expansion, there is a renewed emphasis on quality and consistency even within the small winery industry. Written for the small production program, A Complete Guide to Quality in Small-Scale Wine Making is for the novice to intermediate level winemaker seeking foundational information in chemistry and sensory science as they relate to wine quality at a technical level. Drawing from personal experience as well as scientific literature, this book introduces the core concepts of winemaking before delving into methods and analysis to provide practical insights into creating and maintaining quality in the wine product.

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