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Elsevier

Books in Life sciences

  • Practical Genetic Counselling

    • 3rd Edition
    • Peter S. Harper
    • English
    Practical Genetic Counselling, Third Edition presents the progress in the field of medical genetics. This book covers the broad area of congenital malformation syndromes and dysmorphology. Organized into three parts encompassing 26 chapters, this edition begins with an overview of the main steps in the process of genetic counselling. This text then examines how a Mendelian inheritance may be established by a combination of clinical diagnosis. Other chapters consider the risks in specific groups of chromosomal disorders. This book discusses as well the molecular genetic approaches, which are making an impact in the treatment of major disorders by providing pure and comparatively inexpensive gene products. The final chapter deals with how genetic counselling is contributing to reducing the general burden of genetic disease in the population. This book is a valuable resource for geneticists, neurologists, clinicians, pediatricians, and obstetricians. Readers who are interested to know about genetic disorders will also find this book useful.

  • Mitochondrial Disorders in Neurology

    Butterworth-Heinemann International Medical Reviews
    • 1st Edition
    • Anthony H.V. Schapira + 1 more
    • English
    Mitochondrial Disorders in Neurology provides an overview of mitochondrial diseases. This book discusses the effects of mitochondrial dysfunction based on the relevant biochemistry and molecular genetics. The abnormal muscle and mitochondrial morphology in a variety of clinical presentations from isolated ophthalmoplegia to severe encephalopathy are also elaborated. This text likewise deliberates Leber's hereditary optic neuropathy, neurodegenerative disorders, and respiratory chain defects. Other topics covered include mitochondrial DNA and the genetics of mitochondrial disease; cytochrome oxidase deficiency; use of tissue culture in the diagnosis of mitochondrial disease; and advances in mitochondrial genetics. This publication is a good source for clinicians and students concerned with the defective mitochondrial function.

  • Photosynthetic Reaction Center

    • 1st Edition
    • Volume 2
    • Johann Deisenhofer + 1 more
    • English
    The availability of the photosynthetic reaction center's structure at an atomic resolution of less than three angstroms has revolutionized research. This protein is the first integral membrane protein whose structure has been determined with such precision. Each volume of the Photosynthetic Reaction Center contains original research, methods, and reviews. Together, these volumes cover our current understanding of how photosynthesis converts light energy into stored chemical energy.Volume II details the electron transfer process; it is oriented to the physical aspects of photosynthesis. It thus primarily discusses bacterial photosynthesis and model compounds. Volume II features the very complex and rapidly evolving issues associated with the theory of electron transfer in the bacterial reaction center, and explores picosecond and femtosecond spectroscopy. This volume also covers holeburning spectroscopy; primary events of bacterial photosynthesis with emphasis on the application of large, external electric fields designed to manipulate and probe mechanisms of the initial chemistry; the role of accessory carotenoid pigments; the techniques of infrared spectroscopy and magnetic resonance as applied to photosynthesis; and the interplay between natural and artificial photosynthesis.

  • Advances in Drug Research

    • 1st Edition
    • Volume 19
    • Bernard Testa
    • English
    Each volume in this distinguished series presents authoritative reviews on topics of broad interest in drug research and on novel and established therapeutic classes. Acknowledged experts contribute in areas such as drug design, clinical and molecular pharmacology, drug metabolism, and mechanisms of action. Reviewers have consistently praised Advances in Drug Research for its comprehensive and lucid summaries of up-to-date knowledge.

  • Neuropsychopharmacology

    Proceedings of the 7th International Congress of Pharmacology, Paris, 1978
    • 1st Edition
    • C. Dumont
    • English
    Advances in Pharmacology and Therapeutics, Volume 5: Neuropsychopharmacol... contains the proceedings of the 7th International Congress of Pharmacology held in Paris, France, in 1978. The papers explore advances in the understanding of neuropsychopharmacol... and cover topics ranging from anti-schizophrenic drugs to drug pathways in depression treatment. Pharmacological interferences with nonstriatal dopaminergic systems are also discussed. This volume is comprised of 21 chapters and opens by considering the nanomolar affinity of pre- and post-synaptic dopamine receptors for neuroleptics. The next section deals with drug pathways in the treatment of depression, with particular reference to the biochemical mechanisms of depressive states and the therapeutic effects of some antidepressants. The following chapters examine dopamine receptors in the nucleus accumbens; modulation of mesolimbic dopamine mechanisms via serotonin and GABA; how mesocortical dopaminergic neurons react to stress; and the behavioral consequences of the interaction between morphine, substance P, and nonstriatal dopamine neurons. This book will be of interest to practitioners in biosciences, pharmacology, physiology, psychology, neurology, and medicine.

  • Plant Biochemistry

    • 1st Edition
    • James Bonner + 1 more
    • English
    Plant Biochemistry focuses on the biological processes involved in plants, particularly noting metabolism, electron transport, biogenesis, and germination. The manuscript first offers information on the substructures and subfunctions of plant cell, including cell and subcell, enzymes, ribosomes, nucleus, cellular membranes, mitochondria and electron transport, chloroplast, and the substructure and function of the cell wall. The text then elaborates on basic metabolism. Enzymology, the path of carbon in respiratory metabolism, mono- and oligosaccharides, starch, insulin, and other reserve polysaccharides, and the biogenesis of the cell wall are discussed. The publication explains plant metabolism and control. Discussions focus on plant acids, alkaloid biogenesis, coumarins, phenylpropanes, and lignin, ethylene and polyacetylenes, steroids, and seed development and germination. The book is a valuable source of information for students or professional workers in the plant sciences.

  • Recent Advances in Animal Nutrition

    • 1st Edition
    • W. Haresign + 1 more
    • English
    Recent Advances in Animal Nutrition 1989 focuses on the compositions of animal feeds. The book first discusses legislation and its implication for the feed compounder, including marketing of feeds, medicated feeds, and feed additives. The text highlights residues of veterinary drugs in animal products. Licensing of veterinary products; assessment of the safety of veterinary medicines; and development of performance-enhancin... drugs are discussed. The book also looks at the vitamin requirements and allowances for poultry; effect of pellet quality on the performance of meat birds; and nutrition of rabbits. The text then discusses the prediction of the nutritive value of silage. History of silage energy evaluation; energy prediction and energy prediction relationships; and nutrient response based systems of rationing are described. The book focuses also on the effect of silage additives and wilting on animal performance; optimizing compound feed use in dairy cows with high intakes of silage; and nutrition of lambs. The text then looks at amino acid nutrition of pigs and poultry and etiology of diarrhea in pigs and pre-ruminants. The selection is vital for readers interested in conducting studies on the compositions of animal feeds.

  • Current Approaches to Occupational Health

    Volume 2
    • 1st Edition
    • A. Ward Gardner
    • English
    Current Approaches to Occupational Health 2 is a compilation of articles that review the progress in the fields of occupational health, occupational medicine, and occupational hygiene. The book presents industry reviews of the rubber, coal mining, agriculture, and diving industries; occupational health problems; and toxicology, epidemiology, hazard management, work, education in occupational medicine, and health education at work. Occupational health professionals, physicians, and students will find the book invaluable.

  • Reproductive and Developmental Behaviour in Sheep

    An Anthology from ``Applied Animal Ethology''
    • 1st Edition
    • A.F. Fraser
    • English
    Although intensive husbandry is increasingly applied to sheep, most sheep production around the world is still based on the extensive system. Under these conditions, attempts to improve productivity must take particular account of reproductive and developmental behaviour, as successful sheep production depends heavily on optimal reproduction and development. These topics are presented in this anthology of selected publications on sheep behaviour. The papers have been taken from ten years of Applied Animal Ethology (now Applied Animal Behaviour Science) from its inception in December 1974 to the end of its publication under that title in 1984.

  • Diseases of the Alimentary Tract

    • 1st Edition
    • Clifford F. Hawkins
    • English
    Diseases of the Alimentary Tract covers topics about the symptoms, diagnosis, and treatment of several diseases of the alimentary tract. The book describes the causes, symptoms, diagnosis, and treatment of diseases of the mouth and the esophagus, such as aphthous stomatitis, esophageal disorders, and cancer of the esophagus. The text also discusses the types, etiology, symptoms, diagnosis, complications, and treatment of hiatus hernia. Peptic ulcer is tackled with regard to the causes, association to blood group, influence of hormones, geographical incidence, prognosis, and treatment. The book then tackles the conditions associated with peptic ulcer; gastric operations and their metabolic sequelae; and the problems of gastritis and other local conditions. The text further discusses the environmental causes, local factors, symptoms, signs, diagnosis, and surgery of gastric cancer and the diagnosis and prognosis of gastrointestinal hemorrhage. Problems associated with dyspepsia; diseases of the gall bladder and the pancreas; various gastrointestinal problems; and rare gastrointestinal disorders are also explained. The book also describes Crohn's disease, disorders of the colon, as well as gastrointestinal tract involvement in some systemic diseases. Professional gastroenterologists and students taking courses related to gastroenterology will find the book invaluable.

  • Fetal Endocrinology

    • 1st Edition
    • Miles J. Novy + 1 more
    • English
    Fetal Endocrinology covers many facets of primate reproductive biology. The book discusses some thoughts on the fetoplacental unit and parturition in primates; the development and function of the human fetal adrenal cortex; and postnatum evolution of the adrenal glands of rhesus macaques. The text also describes the regulation of fetoplacental steroidogenesis in rhesus macaque; the comparative biological, immunologic, and chemical properties of the primate chorionic gonadotropins; and urinary estrogens during pregnancy in diverse species. The secretion and physiology of chorionic somatomammotropin in primates; the placental thyroid stimulators and thyroid function in pregnancy; and growth factors in fetal growth and development are also considered. The book further tackles the production and activity of placental releasing hormone; the endocrinology of parturition; and sex-determining genes and gene regulation. The text also looks into the testicular hormone production in fetal rhesus macaque; the control of pituitary gonadotropin secretion in fetal rhesus macaque; and the development of the regulatory mechanisms of the hypothalamic-pituita... system in the human fetus. The development of the fetal adrenals in nonhuman primates and perspectives in fetal endocrinology are also encompassed. Reproductive physiologists, pediatricians, gynecologists, and endocrinologists will find the book invaluable.

  • Vertebral Manipulation

    • 4th Edition
    • G. D. Maitland
    • English
    Vertebral Manipulation: Fourth Edition presents a comprehensive examination of the methods of passive movement treatment. It discusses the effectiveness of gentler manipulation of conscious patients. It addresses the relationship between the treatment and the patient’s symptoms and signs. Some of the topics covered in the book are the organic disorders not involving the vertebrae; disease of the spinal cord; passive physiological intervertebral movement; techniques of mobilization; method of oscillatory movement; postero-anterior central vertebral pressure; and method of progression of the lumbar region. The methods in the application of mobilization are fully covered. An in-depth account of the manipulative techniques is provided. The manipulations are progressions from mobilizations which have increased in strength. Application of such manipulations is completely presented. A chapter is devoted to the movements of the faulty intervertebral joint. Another section focuses on the assessment related to abnormal movements at the initial examination. The book can provide useful information to therapists, doctors, students, and researchers.

  • The Chemistry and Technology of Edible Oils and Fats and Their High Fat Products

    • 1st Edition
    • G. Hoffmann
    • Steve L Taylor
    • English
    The Chemistry and Technology of Edible Oils and Fats and their High Fat Products covers the theoretical and practical aspects associated with the chemistry and technology of oils and fats. The book discusses the chemistry of edible fats; vegetable-oil separation technology; and water- and heat-promoted fat separation from animal and plant "fatty tissues". The text also describes the refining process; the fat-modification processes; and the production of edible-fat products of high fat content. The technologies applied to speciality fats; the storage and transport of oils and fats; and energy demands of the oil-milling and edible-fat processing operations. People involved in the processing of edible oils and fats will find the book useful.

  • Pathobiology of the Endothelial Cell

    • 1st Edition
    • Hymie L. Nossel + 1 more
    • English
    Pathobiology of the Endothelial Cell presents the proceedings of the symposium on the "Pathobiology of the Endothelial Cell" held at Arden House, on the Harriman Campus of Columbia University on June 5-7, 1981. The book discusses the endothelial growth regulation; the stimulation of vascular cell growth by macrophage products; and the control of proliferation and differentiation of endothelial cells. The text also describes vessel wall growth control; the implications of angiogenesis in vitro for tumor biology; and the interactions and activation of coagulation proteases. Platelet adhesion and fibrinogen proteolysis; endothelial protein synthesis; prostaglandins, and endothelial cell-cell interactions are also considered. The book further tackles topics on vascular pathobiology. Biologists, pathologists, biochemists, hematologists, oncologists, immunologists, and microbiologists will find the text invaluable.

  • Recent Advances in the Pharmacology of Toxins

    Proceedings of the First International Pharmacological Meeting Stockholm, 22-25 August, 1961
    • 1st Edition
    • H. W. Raudonat
    • English
    Recent Advances in the Pharmacology of Toxins brings together the proceedings of the Second International Pharmacological Meeting of the International Union of Physiological Sciences, held in Prague, Czechoslovakia, on August 20-23, 1963. The meeting provided a forum for discussing advances in the understanding of the pharmacology of toxins and addressed topics ranging from antagonists of bradykinin to the mode of the spread of tetanus toxin in experimental animals. This volume is comprised of 28 chapters and begins with an analysis of the effects of toxins from microorganisms on mammalian cellular metabolism and structure, followed by a review of SRS-A, a slow-reacting substance of anaphylaxis, as a potential factor in the symptoms produced by venoms and toxins. Subsequent chapters explore the release of pharmacologically active lipids by enzymes contained in toxins; the structure and function of some enzymes in snake venoms, with reference to disulfide linkages; biochemistry and pharmacology of small-molecular compounds of cobra venom; and the role of ganglioside in the mode of action of tetanus toxin. This book will be of particular value to pharmacologists and physiologists.

  • Protides of the Biological Fluids

    Proceedings of the Sixteenth Colloquium, Bruges, 1968
    • 1st Edition
    • H. Peeters
    • English
    Protides of the Biological Fluids presents the functional approach to conformation that combines the physiological significance with physical and chemical appearance of the protein. This book discusses the technical details of purification, determination, or identification of given protein fractions. Organized into three sections, this book begins with an overview of the intramolecular cross-linked synthetic polypeptides that can be used as models for the organized spatial structure of proteins. This text then examines the polarization of fluorescence methods, which provide very sensitive hydrodynamic techniques for studying the internal organization and the rigidity of the polypeptide. Other sections consider the excretion of different classes of immunoglobulins in the external secretions of dogs. This book discusses as well the anti-coli antibody and the poliovirus neutralizing antibody activity of achlorhydric gastric juices. The final section deals with the introduction of gels as a medium for the electrophoresis of proteins. This book is a valuable resource for chemists, biochemists, and geneticists.

  • Life Sciences and Space Research

    Proceedings of the Open Meeting of the Working Group on Space Biology of the Twenty-Second Plenary Meeting of COSPAR, Bangalore, India, 29 May - 9 June 1979
    • 1st Edition
    • R. Holmquist
    • English
    Life Sciences and Space Research, Volume XVIII is a collection of articles on space biology. The book describes the presence of organic molecules found in interstellar space, comets, and meteorites. The text also addresses the role of comets in giving rise to new studies in cometary chemistry, as the source of plasma, or as supplying the mechanism for the formation of amino acids, glycine, and guanine. One paper addresses the possibility of life on the planet Mars touching on chemical reactions of nutrient compound decay and other physio-chemical changes. The book also notes the contribution of cometary volatiles to the study of the primitive earth plus the possible role of metal ions and clays in prebiotic chemistry. Other papers discuss radiation biology concerning both radiobiological results from experiments done in spaceflight and ground laboratories such as the degeneration of rabbit tissues after heavy irradiation. The book then evaluates gravitational biology, including topics such as physiological reactions during acute adaptation to reduced gravity; land plant evolution and gravity; and the development of Polyporus brumalis basidomycete, a kind of fungi, in conditions of weightlessness. Molecular biologists, space engineers, biologists, meteorologists, and genetic engineers will find this book highly valuable.

  • Cardiovascular Review 1984

    • 1st Edition
    • Gerald C. Timmis + 2 more
    • English
    Cardiovascular Review 1984 is an attempt to assimilate most of the clinically germane English-speaking cardiologic literature in as concise and timely a format as possible. Thus, this textual compendium of individual reports represents as current a summary of cardiologic thinking as the publishing process will allow. With the addition of another 1926 references, this work now consists of about 9000 statements on cardiovascular reports appearing in the English-speaking cardiovascular literature. The table of contents has been constructed to reflect the order in which the preponderance of cardiologic literature appears. Thus, ischemic heart disease, valvular heart disease, arrhythmias, and conduction defects have been assigned a high priority reflected by their location in the first few sections of this book. Thereafter, topics ranging from acromegaly to tumors of the heart have been addressed in alphabetical order.

  • A Synopsis of Respiratory Diseases

    • 1st Edition
    • J. Smart
    • English
    A Synopsis of Respiratory Diseases discusses the concept of pulmonary physiology and its diseases. This book is composed of 10 chapters that address the development and treatment of tuberculosis. Some of the topics covered in the book are the essential function of the lungs; transfer of gases; blood gas analysis; definition of acute respiratory failure; different diseases of the nose; ailments of the larynx; conditions of spasm or obstruction of the larynx; types of ventilators; control of respiration; and differential lung function. Other chapters describe the physiological instances leading to carbon dioxide narcosis and some diseases of the trachea. The discussion then shifts to the etiology, histology, and bacteriology of chronic bronchitis. The concluding chapters are devoted to the definition and treatment of emphysema, as well as the diagnosis of tumors of the bronchus. The book can provide useful information to doctors, students, and researchers.

  • Biological Husbandry

    A Scientific Approach to Organic Farming
    • 1st Edition
    • B. Stonehouse
    • English
    Biological Husbandry: A Scientific Approach to Organic Farming covers a proceeding of a symposium organized by International Institute of Biological Husbandry on August 26-30, 1980 at Wye College in London, United Kingdom. Said symposium aims to promote the scientific development of biological or organic agriculture. The text covers topics such as the assessment of conventional, biological, and integrated agriculture; soil use in temperate climates, organic matter cycles in tropical soils, and plant-microbial interactions; biological pest control, the importance of chemical agents and biotechnology in biological husbandry, and allelochemicals in the future of agriculture. The book is recommended for biologists and agriculturists who would like to know more about the studies in biological husbandry and its implications in the field.

  • Mineral Salts Absorption in Plants

    International Series of Monographs on Pure and Applied Biology: Plant Physiology
    • 1st Edition
    • J. F. Sutcliffe
    • P. F. Wareing + 1 more
    • English
    Mineral Salts Absorption in Plants details the contemporary knowledge regarding the mineral salt absorption mechanisms of plants. The title first covers the history of mineral salt absorption in plants, and then proceeds to tackling the experimental materials and methods. Next, the selection discusses the mechanisms of ion transport. Chapter 4 deals with the factors affecting salt absorption, while Chapter 5 talks about salt absorption and metabolisms. In the sixth chapter, the text covers the structural aspects of salt absorption in cells. The seventh chapter discusses the salts relations of vascular plants. The selection also talks about the soil as a source of mineral salts, along with salt tolerance. The book will be of great use to botanists and horticulturists. Students and researchers in the field of mineral nutrition will also benefit from the text.

  • Hormones and the Fetus

    • 1st Edition
    • J. R. Pasqualini + 2 more
    • English
    Volume One of Hormones and the Fetus contained a generalization of the role of hormones during fetal life. In this second volume, the main topics focus on hormonal binding to fetal and maternal plasma proteins, amniotic fluid and placenta; the presence of hormone receptors in the fetal compartment; and the mechanism of action of various hormones in different target tissues of the fetus and placenta. This up-to-date information is of major importance in the study of hormonal activity in fetal life, and the biological effect of hormones through the receptor. The mechanism of fetal sexual differentiation, in which hormones play an important role, is extensively covered.

  • The Actions and Uses of Ophthalmic Drugs

    • 3rd Edition
    • P. H. O'Connor Davies + 2 more
    • English
    The Actions and Uses of Ophthalmic Drugs, Third Edition discuses the application and discrimination in the use of ophthalmic drugs. The book reviews the general pharmacological principles including drug nomenclature, pharmacological classification, pharmacokinetics, pharmacodynamics, and the use of these drugs. Ophthalmic drugs (cycloplegics, mydriatics, miotics) directly or indirectly, stimulate or inhibit a part of the autonomic nervous system connected to the intra-ocular muscles. The text investigates in detail the structure and function of this involuntary nervous system in the orbital region as it is affected by these drugs. The book explains the different drug classifications, their therapeutic and diagnostic purposes, including the ideal properties, indications, contra-indications, mode of action, or adverse effects of cycloplegics, of mydriatics, and of miotics. The book also describes the uses and characteristics of local anesthetics, stains, anti-infective agents, and miscellaneous agents (antihistamines, vasoconstrictors). The text explains the different types of contact lens solutions, application of ocular first aid, as well as, the possible adverse ocular reactions that can occur during ophthalmic drug therapy. This book is suitable for optometrists, pharmacists, pharmacologists, students and professors related to the discipline of optometry and general medicine.

  • Lipid Metabolism in Signaling Systems

    • 1st Edition
    • Volume 18
    • John N. Fain + 1 more
    • English
    Many of the phospholipases and even the receptor for inositol 1,4,5-trisphosphate have recently been cloned and sequenced and play an important role in neurotransmission. Methods developed in recent years for the study of the enzymes and intermediates involved in the regulation of neuronal signal transduction involving phospholipid turnover are presented in this volume.

  • Fundamentals of Radiobiology

    International Series of Monographs in Pure and Applied Biology: Modern Trends in Physiological Sciences
    • 2nd Edition
    • Z. M. Bacq + 1 more
    • English
    Fundamentals of Radiobiology presents a clear picture of the effects of radiation to living organisms. It discusses the steps leading from the absorption of energy to death or final injury. The focus of study is the changes induced at the molecular level by absorbing energy. Some of the topics covered in the book are the methods for determining the direct and indirect action in biological systems, the nature of the initial chemical lesion in cellular radiobiology, the definition of target theory and the meaning of poison theory. The subjects on general radiation chemistry are also covered. The fields of radiation chemistry that will be discussed are the role of excitation, the variation of reactions between gases, liquids, and solids; and the status of free radicals created. The effects of radiation on macromolecules are discussed. The text defines the important role of metabolism in the development of the lesions. An analysis of the interactions of ionizing radiations with is presented. A chapter of the volume is devoted to the radiation chemistry of aqueous systems. Another section of the book focuses on the chemicals which simulate the biological effects of ionizing radiations. The book will provide useful information to doctors, chemists, biologists, radiologists, students and researchers.

  • Pharmaceutical and Biomedical Applications of Liquid Chromatography

    • 1st Edition
    • Volume 1
    • W.J. Lough + 2 more
    • English
    This volume reflects the changes that have taken place in the pharmaceutical industry over the last ten years, most notably the increased importance attached to the question of chirality, the growing influence of biotechnology and the need for more rigorous documentation and validation of analytical methods and procedures.The first part of this book deals with the application of new technology to pharmaceutical and biomedical analysis, reflecting the present needs for increased speed, sensitivity and selectivity in the analysis of drugs. The second chapter provides an overview of capillary electophoresis, which represents one of the most inportant analytical developments to impact directly on pharmaceutical development in recent years. Although not a chromatographic technique, capillary electrophoresis was considered too important to be ignored.Over the last 25 years, liquid chromatography has grown into a mature analytical technique and many of the fundamental issues concerned with retention and separation are well defined. The practitioners of modern liquid chromatography spend as much time in the development of techniques for sampling handling and automation as they do in the development of the separation. Therefore, Part Two of this book describes some of the recent advances in the areas of sample handling and the isolation of compounds from biological samples, including solid phase extraction, restricted access media for direct injection, coupled column technology and microdialysis. Similarily, Part Three contains two chapters concerned with liquid chromatographic methods for the isolation of drug substances, peptides and proteins from other complex media.The pharmaceutical industry and the process of drug development are highly regulated and the increasing importance that the regulatory authorities attach to validation has had a significant impact on the analytical techniques used for the analysis of drugs. Although this has increased the workload of analysts in the pharmaceutical industry, it has also improved the quality of analytical methods used in the support of investigational and new drug applications as well as the quality of methods published more recently in the literature. Consequently, Part Four of this volume describes approaches to the optimization and validation of liquid chromatography methods for the analysis of drugs in the bulk form, in pharmaceutical formulations and biological fluids.

  • Surface-Active Quaternary Ammonium Germicides

    • 1st Edition
    • Carl A. Lawrence
    • English
    Surface-Active Quaternary Ammonium Germicides accumulates in the pages of one volume a review of the history, chemistry, biology, and application of the quaternary ammonium salts that have appeared in print to date. The quaternary ammonium surface-active antiseptics have secured a prominent and important place in the fields of medicinal and general disinfection during the past decade. These compounds are of particular interest in that, unlike most other disinfectants, they exhibit not only germicidal action but also surface-active, detergent, and wetting properties.

  • Essays in Toxicology

    Volume 4
    • 1st Edition
    • Wayland J. Hayes
    • English
    Essays in Toxicology, Volume 4 covers three essays on habituating drugs, on the kinetics of the active-site-directed irreversible inhibition, and the hidden effects of trace elements. The first essay examines certain dependence-producing drugs; the mechanism of tolerance to barbiturates by changes in drugs metabolism; the distribution of barbiturates to the central nervous system; and the urinary excretion of barbiturates. The formation of morphine from heroin and codeine, and the dealkylation to form normorphine and to reduce naloxone to another compound is also considered in the first essay. The second essay discusses the time-course of enzyme inhibition at single-inhibitor concentrations and the effect of various inhibitor concentrations on the rate constants governing inhibition. The third essay is about the recondite toxicity of trace elements, taking into consideration the effects of these trace elements on body weight, survival, and longevity, clues to mechanisms of toxicity, and the production of chronic diseases simulating human disorders. Toxicologists, oncologists, biochemists, and pharmacologists will find the book invaluable.

  • Clostridium Difficile

    Its Role in Intestinal Disease
    • 1st Edition
    • Rial D. Rolfe
    • English
    Despite the tremendous progress made during the last few years in understanding the pathogenesis, epidemiology, diagnosis, and treatment of Clostridium difficile-associated intestinal disease, many extremely important and fundamental questions remain to be answered. The objectives of this book are to summarize the available information regarding Clostridium difficile and its role in intestinal disease and to serve as a basis for future investigations in this challenging area.Clostridium difficile: its role in Intestinal Disease. An excellent volume that should appeal not only to the devotee of C difficile but to all gastroenterologists and microbiologists, this will not languish on my library shelves like so many other books I have reviewed. It will be regularly thumbed. --R.H. George, consultant microbiologist, Children's Hospital, BirminghamClostridiu... difficile: Its Role in Intestinal disease. The book is well written and informative; it has a vast amount of information packed in it...this book would be a welcome addition to the researchers and clinicians interested in C difficile-associated intestinal diseases. --Edward Balish, University of Wisconsin Medical School

  • Controlled Breeding in Farm Animals

    • 1st Edition
    • I. Gordon
    • English
    This textbook provides a detailed view of the different ways in which reproduction in cattle, sheep, pigs and horses can be controlled and manipulated. It is primarily of interest to students of animal science and veterinary medicine, but will also be of use to those who are concerned with the practical aspects of reproduction control, whether in an advisory capacity or in applying techniques on the farm itself. A major objective of the book is to draw attention to information which may be used directly to increase the efficiency of the livestock industry.

  • Ten Studies Into Psychopathic Personality

    A Report to the Home Office and the Mental Health Research Fund
    • 1st Edition
    • Michael Craft
    • English
    Ten Studies Into Psychopathic Personality concerns ten studies made on psychopathic disorders in Britain from 1958 to 1963. These studies cover 100 subjects who were admitted at the Balderton Hospital in 1958. These studies cover subjects such as diagnostic analysis, E.E.G. technique, parental separation and severity disorder, conscience, and prognosis of psychopaths. Six studies describe work on patient admissions for treatment of psychopathic disorders, while four reports investigate hypotheses through comparison of those admissions to groups of normal, delinquent, and psychopathic individuals. These reports show a continuum in personality disorder from normality, to minor behavioral disorders to extreme psychosis. Some general conclusions note that no evidence exists between direct genetic endowment from parent to psychopathic traits of children, as well as more studies need to clinically define psychopathic behavior from lesser personality disorders. Other conclusions show very little knowledge at hand for effectively treating psychopathic behavior; other results point to differential improvement to different treatments. These studies will interest, psychiatrists, psychologists, behavioral scientists, researchers and academicians dealing with deviant human behavior.

  • Marine Mammals and the Exxon Valdez

    • 1st Edition
    • Thomas R. Loughlin
    • English
    The oil spill disaster that occurred when the Exxon Valdez ran aground has become part of the iconography of ecological disaster. This book synthesizes previously confidential data only recently released by the U.S. government. The data concerns the effects of this nightmarish spill on marine mammals, such as sea otters, harbor seals, killer whales, and humpback whales. Because many of the book's contributors were on site within 24 hours of this 11 million gallon catastrophe, the book is a unique longitudinal study of the demise of an ecosystem due to a single acute environmental perturbation.These certain-to-be-influe... results reported here should assist marine biologists, pathologists, toxicologists, environmentalists, engineers, and coastal planners in assessing the nature of this now legendary disaster.

  • Toxicology

    Proceedings of the 7th International Congress of Pharmacology, Paris, 1978
    • 1st Edition
    • Y. Cohen
    • English
    Advances in Pharmacology and Therapeutics, Volume 9: Toxicology is a collection of papers that tackles advances in toxicological research in context of pharmacology. The text first covers reactive metabolites and their implications for toxicology. Next, the selection deals with the experimental and clinical correlations of behavioral toxicology. The text also tackles toxicology and pharmacology of topical application. The book will be of great use to researchers and practitioners of health related disciplines.

  • Halogenated Benzenes, Toluenes and Phenols with Water

    Solubility Data Series
    • 1st Edition
    • Ari L. Horvath + 2 more
    • English
    Solubility Data Series, Volume 20: Halogenated Benzenes, Toluenes and Phenols with Water contains a comprehensive collection and critical evaluation of published solubility data for halogenated benzenes, halogenated toluenes, and halogenated phenols in water prior to 1983. This volume is concerned entirely with the solubility behavior for condensed systems, such as solid or liquid solutes in liquid solvents, including the general behavior of the evaluated solubilities of water in various organic constituents as a function of temperature. This book focuses on liquid-liquid, solid-liquid, and multicomponent (organic-water-salt) systems. The solubilities of ordinary water and heavy water that have been determined in 29 organic liquids, which in all cases the heavy water was found less soluble than the ordinary water are also elaborated. The halogenated compounds outlined in this text have been organized according to the Hill System. This publication is beneficial to chemists and students concerned with the solubility data for halogenated benzenes, halogenated toluenes, and halogenated phenols in water.

  • Mode of Action, Metabolism and Toxicology

    Pesticide Chemistry: Human Welfare and the Environment
    • 1st Edition
    • S. Matsunaka + 2 more
    • English
    Pesticide Chemistry: Human Welfare and the Environment, Volume 3: Mode of Action, Metabolism and Toxicology covers the proceeding of the Fifth International Congress of Pesticide Chemistry. This book is organized into three parts that tackle relevant issues regarding the use of pesticide. The opening part tackles topics relevant to the biochemistry of pests and mode of action of pesticides, such as influence of chlorinated and parathyroid insecticide on cellular calcium regulatory mechanisms; behavioral and lethal actions of amidines on invertebrates; and insect chitin synthetase as biochemical probe for insecticidal compounds. The second part encompasses metabolism and degradation of pesticides and xenobiotics and includes topics on propesticides; selective toxicity conferred by activation; and comparative biochemistry of animal, plant, and microorganism oxidases. The last part covers the toxicology of pesticides and xenobiotics, including the role of biochemical studies in modern toxicological assessment of pesticides; neurophysiological and behavioral assessment of pesticide toxicity; and genetic toxicology applied to the assessment of mutagenic, carcinogenic, and teratogenic action of pesticides and related compounds. This book will be of great interest to chemists, biologists, botanists, and entomologists or professionals whose line of work involves the use of pesticides and who are concerned with pesticide side-effects to the users and the environment.

  • Dale's Principle and Communication between Neurones

    Based on a Colloquium of the Neurochemical Group of the Biochemical Society, Held at Oxford University, July 1982
    • 1st Edition
    • Neville N. Osborne
    • English
    Dale's Principle and Communication Between Neurones is based on a colloquium of the Neurochemical Group of the Biochemical Society, held at Oxford University, July 1982. This book focuses on communication between neurones by means of chemical signals. The book contains an introductory chapter by V. P. Whittaker and nine further chapters on various aspects of the chemical communication processes between neurones. Topics covered include chemical communication between excitable cells; the neuroendocrine division of the nervous system; evidence for a neurone having the capacity to use two chemicals in the same process; and non-synaptic interneuronal communication. Each article is based on the excellent lectures given by the main authors and the discussion which ensued in the one-day colloquium held in Oxford. The final chapter is a specially invited contribution by Drs. Polak and Varndell, who agreed to produce an article on their new method of localising transmitter-like molecules at the electron-microscopic level.

  • Wheat Studies - Retrospect and Prospects

    • 1st Edition
    • Volume 3
    • H. Kihara
    • English
    This authoritative work has been written by a man whose career as an active wheat geneticist has spanned sixty years and has earned him a world-wide reputation. The book contains descriptions and much original data on genetical and cytogenetical findings concerning cultivated wheats and their relatives. It covers chromosomal analyses, genome analyses, ancestors of wheat, artificial synthesis of wheat, evidence of cytoplasmic inheritance and variations of wild species. The author explains how these facts and concepts have been discovered, points out the importance inherent in these discoveries, and shows how they can be utilized in genetical and breeding studies. Special emphasis is placed on the motives, processes and development of the studies.

  • Low Blood Pressure

    Its Causes and Significance
    • 1st Edition
    • J. F. Halls Dally
    • English
    Low Blood Pressure: Its Causes and Significance focuses on the important and interesting aspects of low arterial pressure. This book discusses the vasomotor control of arterial pressure; significance of low arterial pressure; autonomic-endocrine influences; and symptomatology of acquired hypopiesis. The parasympathetic or extended vagus system; arteriosclerosis of large vessels; psychical low arterial pressure; and agents causing vascular dilatation are also deliberated. This text likewise covers the exanthematous infections of doubtful etiology; atrophic cirrhosis of the liver; occasional difficulties in diagnosis; and control of low arterial pressure. This publication is intended for medical practitioners and clinicians aiming to acquire knowledge of low arterial pressure and its associations.

  • Neuro-Ophthalmology

    • 1st Edition
    • R. Lindsay Rea
    • English
    Neuro-Ophthalmology provides information pertinent to the neuro-ophthalmologic... examination of the eye. This book discusses the anatomy and function of the eye as well as its various diseases. Organized into 17 chapters, this book begins with an overview of the various equipment and methods used in the examination of the eye, including the Snellen's test type, a 13 dioptre lens, and electric ophthalmoscope. This text then discusses the principal reactions of the normal pupil, including the direct light reflex, reflex to accommodation, the spino-pupillary reflex, the psychical reflex, the orbicularis reflex, and the oculo-sensory reflex. Other chapters consider the anatomy of the muscles and nerves of the eye as well as it adnexa. This book discusses as well the condition of optic atrophy and its various types. The final chapter deals with the distinction between headache and neuralgia. This book is a valuable resource for ophthalmic surgeons and ophthalmologists.

  • Food and Agriculture in Global Perspective

    Discussions in the Committee of the Whole of the United Nations
    • 1st Edition
    • Toivo Miljan + 2 more
    • English
    Food and Agriculture in Global Perspective: Discussions in the Committee of the Whole of the United Nations presents the problem of food and agriculture in its total global international perspective from the point of view of the specialized agencies of the United Nations system and the States Members of the United Nations. The book discusses the problem of food and agriculture and its handling in the global perspective; groups the statements of the problem around international agency views and around the views of Member States; and presents the progress report of efforts by international agencies and by States. The text also describes the excerpts from the technical documents, and statements of Agency representatives and Member States in the seven specific issue areas found in the Agreed Conclusions of the Committee.

  • Chemical Manipulation of Crop Growth and Development

    Proceedings of Previous Easter Schools in Agricultural Science
    • 1st Edition
    • J S McLaren
    • English
    Chemical Manipulation of Crop Growth and Development presents a critical review of the plant growth regulators in field crops. It discusses the strategies to discover plant growth regulators for agronomic crops; the methods of modifying stomatal movement; and the possible use of chemicals for photorespiration control. Some of the topics covered in the book are the hormonal control of photosynthesis and assimilate distribution; manipulation of crop growth by ethylene and some implications of the mode of generation; genetic and chemical manipulation of crops to confer tolerance to chemicals; and effects of allelochemicals on crop growth and development. The control of development of potato plant by using endogenous and exogenous growth regulators is covered. The analysis of crop physiology to assess plant growth regulation in sugar beet is also discussed. An in-depth analysis of the influence of auxin antagonists on pod and seed number is provided. The effect of foliar applications of synthetic plant growth regulators on the agronomic characteristics of field-growth corn is presented. A chapter is devoted to the use and effect of cerone in developing winter barley. The book can provide useful information to farmers, botanists, students, and researchers.

  • Recent Advances in Liquid-Liquid Extraction

    • 1st Edition
    • C. Hanson
    • English
    Recent Advances in Liquid-liquid Extraction focuses on the applications of liquid extraction. The selection first discusses solvent extraction. Concerns include organic and inorganic separations, mass transfer process, solvent extraction economics, and coalescence in liquid-liquid systems. The book focuses on the chemistry of solvent extraction. Extraction by acidic organophosphorus compounds; extraction by phosphorus-bonded oxygen-donor solvents; extraction by high-molecular weight amines; and synergistic extraction are elaborated. The book also focuses on industrial organic processes; industrial contacting equipment; response characteristics and control of extraction processes; and calculation of contactors with longitudinal mixing. The selection presents the study of longitudinal mixing in liquid-liquid contactors. Rotating disc contactors, packed columns, vibrating plate extractors, and Oldshue-Rushton columns are described. The text also discusses heat transfer by direct liquid-liquid contact and the coalescence of liquid droplets and liquid dispersion. The selection is a vital source of data for readers interested in liquid extraction.

  • Pharmacology of Histamine Receptors

    • 1st Edition
    • C. R. Ganellin + 1 more
    • English
    Pharmacology of Histamine Receptors presents a summary of the pharmacology of histamine receptors. It discusses the research and developments made in the use of histamine. It addresses the biological actions of the drug in various pathological instances. Some of the topics covered in the book are the classification of histamine receptors; mepyramine and related histamine antagonists; activity relationships of drugs acting at histamine receptors; chemical structure of histamine; effects of methyl substituents in histamine; enzymes involved in histamine metabolism; and histamine in body fluids. The cellular sources of histamine in tissues and blood are fully covered. The relationship of the mast cell to basophil is discussed in detail. The text describes in depth the urinary excretion of histamine and metabolites. The pathological conditions in man are presented completely. A chapter is devoted to the fundamental properties of adenylate cyclase and its measurement. The book can provide useful information to pharmacists, doctors, chemists, students, and researchers.

  • Autoradiography and Immunocytochemistry

    Practical Methods in Electron Microscopy
    • 1st Edition
    • M.A. Williams
    • Audrey. M. Glauert
    • English
    Autoradiography and Immunocytochemistry sets out in detail the preparation of autoradiographs and methods of preparing and use of immunological staining reagents. This book begins with an introduction to the demand for autoradiography and immunocytochemistry and their most advantageous use, followed by a discussion on the immunocytochemistry at the electron microscopical (EM) level in relation to the preparation of labeled antibodies. Other topics include the general remarks on “staining” with antibodies; applying Fer-Ab conjugates to ultrathin sections; and controls in immunoferritin staining. The multistep antibody staining methods with unmodified proteins; control observations in staining experiments using lectins; and pattern analysis in EM immunocytochemistry are also covered. This text concludes with a description of the preparation of electron microscope autoradiographs, including the radioisotopes in EM autoradiography, preparation of radioactively-labele... tissues and cells, and methods of applying nuclear emulsions. This publication serves as a detailed laboratory guide for researchers and workers to successfully conduct electron microscope techniques.

  • Viral Interference and Interferon

    • 1st Edition
    • R. D. Andrews
    • English
    Viral Interference and Interferon details the developments in the control of virus infections by natural means. The book is comprised of eight chapters that discuss various aspects of interferon. The text first introduces the main concepts of the subject matter. The succeeding chapter discusses various concerns about interferon, including the production, nature, mechanisms, and mode of actions. The book also covers interferon in humans and animals, and its significance. The text will be of great use to students of microbiology, virology, genetics, and immunology.

  • Infections of the Nervous System

    Butterworths International Medical Reviews
    • 1st Edition
    • Peter G. E. Kennedy + 1 more
    • English
    Infections of the Nervous System aims to continue the legacy of its predecessor, Modern Trends in Neurology. Its goal is to produce annually a monograph on a topic in clinical neurology in which progress through research has brought about new concepts of patient management. This book is organized into 13 chapters. It highlights the areas or subjects in which significant advances have been made which also have relevance to the treatment of patients. It covers a number of important aspects of different infectious diseases of the nervous system including acute bacterial meningitis, tuberculosis of the nervous system, spirochaetal infections of the nervous system, and fungal diseases of the central nervous system. This book is intended for use by physicians who deal with the problems of neurological disorder on a daily basis, whether they are neurologists, neurologists in training, or those in related fields such as neurosurgery, internal medicine, psychiatry, and rehabilitation medicine.

  • Urine Analysis

    • 1st Edition
    • Byomkes Das Gupta
    • English
    Urine Analysis presents the theory and methods of urine analysis, which serves as a guide for physicians and medical laboratory technicians. Topics discussed in the book include the physical examination of urine; its chemical examination; microscopical examination; and Ehrliches Diazo reaction. Physicians and medical laboratory technicians will find the book a very valuable reference material.

  • Aminergic and Peptidergic Receptors

    Satellite Symposium of the 3rd Congress of the Hungarian Pharmacological Society, Szeged, Hungary, 1979
    • 1st Edition
    • E. S. Vizi + 1 more
    • English
    Advances in Pharmacological Research and Practice, Volume VII: Aminergic and Peptidergic Receptors focuses on how neurotransmitters, drugs, and hormones affect the plasma membrane. Composed of 14 chapters, the book outlines the manner by which presynaptic receptors involved in chemical neurotransmission function. The text then presents various laboratory experiments done to animals to determine how these receptors affect the plasma membrane of these subjects. One of the internal body parts examined is the heart. The variation in sensitivity of opiate receptors is also discussed, focusing on the effect of opioid peptides and morphine on the nigrostriatal axon terminals. The book also discusses the biochemical and pharmacological assets of opiate receptors among mollusks; the upshot of peptides upon biogenic amines of the central nervous system; and how gastrin analogues affect the gastrin receptor of the stomach. This book is a great find for highly trained scholars in the field of receptor research, including biochemists, chemists, pathologists, morphologists, physiologists, and pharmacologists.

  • Current Approaches to Occupational Health

    Volume 3
    • 1st Edition
    • A. Ward Gardner
    • English
    Current Approaches to Occupational Health deals with problems and progress in relation to occupational health. This book is organized into 21 chapters written by different contributors. The occupational health issues covered by these chapters include ethical problems in occupational medicine, the role of legislation, regulation and enforcement in occupational health, the monitoring of occupational risks for cancer and the identification and intervention for problem drinkers at work. This book will be of interest to occupational health students and practitioners and to other medical professionals.

  • Opiate Receptors and the Neurochemical Correlates of Pain

    Proceedings of the 3rd Congress of the Hungarian Pharmacological Society, Budapest, 1979
    • 1st Edition
    • Susanna Fürst
    • English
    Opiate Receptors and the Neurochemical Correlates of Pain, Volume V, documents the proceedings of the 3rd Congress of the Hungarian Pharmacological Society held in Budapest, 1979. The congress offered a good opportunity to stimulate discussions and exchange of ideas between scientists from various countries who approach the problem of narcotics and pain mechanisms in different ways. The 27 contributions in this volume have enriched knowledge in this rapidly expanding field of pharmacology. This volume begins with a discussion of opiate receptors. The results suggest the interaction of various morphine-like drugs with different opiate receptor populations. The existence in nerve tissue of specific opiate receptors binding morphine and other opioids has led to the assumption of endogenous ligand for opiate receptors. One section of the present volume is devoted to enkephalins and endorphins, their structure-activity relationships, interactions with transmitter and other systems, their behavioral effects, and to factors controlling their release. Some other aspects of nociception; the pathways involved in the mode of action of different types of analgesics, e.g. narcotics and non-narcotics; and their relations to inflammation and active substances, such as prostaglandins and substance P, are discussed from various aspects.

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