Mitochondria in Obesity and Type 2 Diabetes
Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases
- 1st Edition - April 12, 2019
- Editors: Beatrice Morio, Luc Penicaud, Michel Rigoulet
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 1 1 7 5 2 - 1
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 1 1 8 5 9 - 7
Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories a… Read more
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Request a sales quoteMitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key concepts on topics such as the role of mitochondria in adipose tissue, cancer, cardiovascular comorbidities, skeletal muscle, the liver, kidney, and more. This book is a must-have reference for students and educational teams in biology, physiology and medicine, and researchers.
- Synthesizes actual knowledge on mitochondrial function
- Provides an integrated vision of each tissue in the etiology of obesity and type 2 diabetes
- Identifies the interactive networks that involve alteration in mitochondrial mass and function in disease progression
- Highlights the role played by mitochondria in the prevention and treatment of obesity and type 2 diabetes
1. Mitochondrial function and structure
2. Mitochondria as signaling platforms
3. Hormonal and humoral regulation of mitochondrial function
4. Nutritional regulation of mitochondrial function
5. Mitochondrial DNA genetic and heteroplasmy
6. Role of mitochondria in the skeletal muscle metabolism in obesity and type 2 diabetes
7. Role of mitochondria in the metabolism of adipose tissues in obesity and type 2 diabetes
8. Role of mitochondria in the liver metabolism in obesity and type 2 diabetes
9. Role of mitochondria in the pancreatic beta-cells metabolism in obesity and type 2 diabetes
10. Role of mitochondria in the cardiovascular comorbidities associated to obesity and type 2 diabetes
11. Role of mitochondria in the regulation of kidney function and metabolism in type 2 diabetes
12. Role of mitochondria in the regulation of the central nervous system in obesity and type 2 diabetes
13. Impact of fetal programming on mitochondrial function and susceptibility to obesity and type 2 diabetes
14. Role of mitochondria in cancers associated to obesity and type 2 diabetes
15. Role of mitochondria in neurodegeneration in obesity and type 2 diabetes
16. Mitochondria as a target of drug toxicity and pollution: potential involvement in the development of obesity and type 2 diabetes
17. Impact of lifestyle and clinical interventions on mitochondrial function in obesity and type 2 diabetes
18. State of knowledge and recent advances in prevention and treatment of mitochondrial dysfunction in obesity and type 2 diabetes
19. Concluding chapter on "Mitochondria in obesity and type 2 diabetes"
- No. of pages: 459
- Language: English
- Edition: 1
- Published: April 12, 2019
- Imprint: Academic Press
- Paperback ISBN: 9780128117521
- eBook ISBN: 9780128118597
BM
Beatrice Morio
LP
Luc Penicaud
of different boards among which the CNRS Scientific Commission on Physiology (as President), the INRA Scientific Council, and the commission of the National Program on Diabetes. He is the author of over 215 international scientific publications, especially in the field of brain nutrient sensing and the role played by mitochondria as molecular actors.
MR
Michel Rigoulet
processes. More recently, his group explored the role of ROS production in the regulation of mitochondrial biogenesis. Michel Rigoulet is a member of the Organizing Committees of the French Group on Bioenergetics (GFB) and of the European Bioenergetics Conferences (EBEC).