Skip to main content
Elsevier
View Cart
My account

Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

BooksJournals

    • Pharmacology of Central Synapses

      • 1st Edition
      • October 22, 2013
      • V. V. Zakusov
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 4 3 1 6
      • eBook
        9 7 8 1 4 8 3 1 4 6 7 3 7
      Pharmacology of Central Synapses deals with the pharmacology of the central nervous system and the mode of action of neurotropic drugs based on their influence on synaptic transmission. The neuronal structure of the nervous system, the structure of the synapses, and the phenomena of electrochemical transmission are discussed in this context. The main propositions of the synaptic theory of the action of neurotropic drugs, based on morphological, physiological, and biochemical findings, form the conceptual basis of this book. Comprised of eight chapters, this book examines the effect of neurotropic drugs on the synaptic transmission in reflex, projection, and association (commissural) tracts. The specific effects of various narcotics, neuroleptics, tranquillizers, analgesics, antidepressants, and stimulants on synaptic transmission in various structures of the central nervous system and at its different levels are described. This text also considers the differences in the sensitivity to such drugs of various synapses and their influence on the selectivity of drug action. This book explains the influence of neurotropic drugs on such aspects of nervous activity as impulse summation, after-discharge and functional lability, central inhibition, and the neurochemical mechanisms, particularly those involving monoaminergic, cholinergic, serotoninergic, and GABA-ergic components of synaptic transmission. The final chapter focuses on the effect of psychotropic drugs on behavior. This book will be helpful to scientists representing all the major areas of pharmacology, including clinical pharmacology and toxicology, as well as to internists, psychiatrists, neurologists, and anesthesiologists.

    • Epidemiology

      • 1st Edition
      • October 22, 2013
      • Jillian M. Birch
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 3 3 0 6
      • eBook
        9 7 8 1 4 8 3 1 8 9 1 1 6
      Advances in Medical Oncology, Research and Education, Volume III: Epidemiology covers the proceedings of the 12th International Cancer Congress. The title presents papers that deal with the epidemiological aspect of oncology. The first part of the text covers cancer epidemiology, and then proceeds to tackling occupational cancer. Next the selection talks about seroepidemiology and human cancer. The text also details the interaction between genetic and environmental factors in human cancer. The book will be of great use to students, researchers, and practitioners of oncology.

    • The Physiology and Pharmacology of the Microcirculation

      • 1st Edition
      • October 22, 2013
      • Nicholas A. Mortillaro
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 3 7 6 4
      • Hardback
        9 7 8 0 1 2 5 0 8 3 0 2 7
      • eBook
        9 7 8 1 4 8 3 2 6 2 0 8 6
      The Physiology and Pharmacology of the Microcirculation, Volume 2, discusses the microcirculatory function of specific organ systems. The first volume of The Physiology and Pharmacology of the Microcirculation presented some general aspects of microcirculatory function and then concentrated on the microcirculation of a specific organ system, namely, brain, eye, heart, and kidneys. This second and final volume continues the presentation of microcirculatory function of specific organ systems. The book begins with a chapter on the microcirculation of the lungs, with a description of its microcirculatory features and current methods of study. This is followed by separate chapters on the microcirculation of the splanchnic organs. These include the stomach, emphasizing hemodynamics, tissue oxygenation, and control of blood flow; the small and large intestine. Subsequent chapters deal with the microcirculatory responses of both the liver and spleen to different physiological and pharmacological challenges; the microcirculation of the skin, with emphasis on human microcirculation; normal and abnormal microcirculatory dynamics in skeletal muscle; microcirculation of bone; and microcirculation of the salivary glands and exocrine pancreas. The final chapter presents a selective review of pathological events involving the microcirculation, with the emphasis directed toward human diseases.

    • Microwave Fixation of Labile Metabolites

      • 1st Edition
      • October 22, 2013
      • C. Leroy Blank + 2 more
      • English
      • Hardback
        9 7 8 0 0 8 0 2 9 8 2 9 0
      • Paperback
        9 7 8 1 4 8 3 1 2 6 6 3 0
      • eBook
        9 7 8 1 4 8 3 1 5 9 0 5 8
      Microwave Fixation of Labile Metabolites documents the proceedings of an official Satellite Symposium of the 8th International Congress of Pharmacology held in Tokyo, Japan, on 25 July 1981. The Symposium was entitled ""Drug Effects on Rapidly Metabolized Compounds in the CNS: Rapid Tissue Fixation with Microwave Irradiation."" The volume begins with a discussion of the use of microwave irradiation to study the concentration and interrelationships of neurochemicals in the brain. This is followed by papers on the effects of immobilization on the increases in cerebellar cyclic GMP induced by cold exposure or apomorphine; importance of rapid enzymatic inactivation prior to the determination of endogenous levels of catecholamines; use of glycolic acid to study catecholamines in the brain following microwave irradiation. Also include are studies on methods for preventing the post mortem increase in γ-aminobutyric acid (GABA); the effect of microwave irradiation on catecholamine levels in the central nervous system; and effect of microwave irradiation in the brain histamine level of rats.

    • Screening Methods in Pharmacology

      • 1st Edition
      • October 22, 2013
      • Robert Turner + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 7 0 4 2 5 2 7
      • Paperback
        9 7 8 1 4 8 3 2 4 7 7 9 3
      • eBook
        9 7 8 1 4 8 3 2 6 4 2 3 3
      Screening Methods in Pharmacology, Volume II is a collection of papers that presents practical techniques and information on the selection of a screening program for a particular pharmacological activity. The book contains the most reliable, simplest, and the most preferred screening methods in pharmacology. The text presents screening methods for alpha and beta Adrenergic blocking agents; compounds for antianginal activity; topical products for excessive eccrine sweating; antidepressant agents; and agents with analgesic and analgesic antagonist activity. Pharmacologists, pharmacists, researchers, and physicians will find this book a good source of information.

    • Drug Design

      • 1st Edition
      • October 22, 2013
      • E. J. Ariëns
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 2 6 4 8
      • eBook
        9 7 8 1 4 8 3 2 1 6 0 7 2
      Drug Design, Volume V covers the fundamental approaches to the development of bioactive compounds. The book discusses the utilization of operational schemes for analog synthesis in drug design; the design of enzyme inhibitors (transition state analogs); and the significance of structure-absorption... relationships for drug design. The text describes the role of charge-transfer processes in the action of bioactive materials, as well as the approaches to the rational combination of antimetabolites for cancer chemotherapy. The physicochemical, quantum chemical, and other theoretical techniques for the understanding of the mechanism of action of central nervous system (CNS) agents, such as psychoactive drugs, narcotics, and narcotic antagonists and anesthetics, are also encompassed. Chemists, biochemists, pharmacologists, and people involved in drug design will find the book invaluable.

    • Bacterial Endotoxins

      • 1st Edition
      • October 22, 2013
      • George Weinbaum + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 2 4 5 7
      • eBook
        9 7 8 1 4 8 3 2 1 5 8 8 4
      Microbial Toxins, Volume IV: Bacterial Endotoxins covers a general introduction of bacterial endotoxins, as well as research concerning structure (both morphological and physical), chemistry, immunology, biosynthesis, and genetics of bacterial endotoxins. The book describes the general characteristics of bacterial endotoxins; the anatomy and chemistry of Gram-negative cell envelopes; and the physical structure of bacterial lipopolysaccharides. The text also discusses the isolation and chemical and immunological characterization of bacterial lipopolysaccharides; the chemistry of the unique carbohydrates of bacterial lipopolysaccharides; and the relation of bacteriophage attachment to lipopolysaccharide structure. The chemical and biological heterogeneity of endotoxins, as well as the biosynthesis of the core region of lipopolysaccharide are also considered. The book further tackles the biosynthesis of O-antigens and the genetic aspects of biosynthesis and structure of Salmonella lipopolysaccharide. Microbiologists, biochemists, bacteriologists, immunologists, and people involved in biochemical research will find the book useful.

    • Mode of Action, Metabolism and Toxicology

      • 1st Edition
      • October 22, 2013
      • S. Matsunaka + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 8 0 3 1
      • eBook
        9 7 8 1 4 8 3 1 5 0 4 5 1
      Pesticide Chemistry: Human Welfare and the Environment, Volume 3: Mode of Action, Metabolism and Toxicology covers the proceeding of the Fifth International Congress of Pesticide Chemistry. This book is organized into three parts that tackle relevant issues regarding the use of pesticide. The opening part tackles topics relevant to the biochemistry of pests and mode of action of pesticides, such as influence of chlorinated and parathyroid insecticide on cellular calcium regulatory mechanisms; behavioral and lethal actions of amidines on invertebrates; and insect chitin synthetase as biochemical probe for insecticidal compounds. The second part encompasses metabolism and degradation of pesticides and xenobiotics and includes topics on propesticides; selective toxicity conferred by activation; and comparative biochemistry of animal, plant, and microorganism oxidases. The last part covers the toxicology of pesticides and xenobiotics, including the role of biochemical studies in modern toxicological assessment of pesticides; neurophysiological and behavioral assessment of pesticide toxicity; and genetic toxicology applied to the assessment of mutagenic, carcinogenic, and teratogenic action of pesticides and related compounds. This book will be of great interest to chemists, biologists, botanists, and entomologists or professionals whose line of work involves the use of pesticides and who are concerned with pesticide side-effects to the users and the environment.

    • Recent Advances in Neuropsycho-Pharmacology

      • 1st Edition
      • October 22, 2013
      • B. Angrist + 2 more
      • English
      • Hardback
        9 7 8 0 0 8 0 2 6 3 8 2 3
      • Paperback
        9 7 8 1 4 8 3 1 2 2 3 0 4
      • eBook
        9 7 8 1 4 8 3 1 5 4 7 2 5
      Recent Advances In Neuropsychopharmacol... contains selected papers from the 12th Congress of the Collegium Internationale Neuro-Psychopharmaco... held in Gõteborg, Sweden, 22-26 June 1980. The 47 papers in the volume are organized into six parts. The papers in Part I deal with the subject of psychostimulants in psychiatric research. Topics covered include the effect of chronic d-amphetamine and chronic apomorphine treatment on non-human primate social and solitary behavior; and the behavioral effects of dopamine agonists. Part II assesses the prescription of psychotropic drugs by general practitioners. Part III examines blood platelets as a model system for central monoaminergic neurons. Part IV focuses on anxiety pathways in the brain. Part V considers prospects for a biochemical classification system in psychiatry. Part VI presents pharmacokinetic studies of psychotropic drugs. Part VI contains two papers on the renal function and renal histology of lithium patients on maintenance lithium therapy and pre-lithium patients; and the treatment of refractory schizophrenia.

    • Keep off the Grass

      • 1st Edition
      • October 22, 2013
      • Gabriel G. Nahas
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 4 3 2 8
      • Hardback
        9 7 8 0 0 8 0 2 3 7 7 9 4
      • eBook
        9 7 8 1 4 8 3 2 8 0 3 7 0
      Keep Off the Grass is a scientific inquiry into the scientific effects of marijuana. Marijuana, like most drugs ingested by man, gives the user the impression that his senses are enhanced, when in fact they have been distorted and impaired. This book is composed of 27 chapters, and starts with a brief introduction to the history of marijuana, the properties of its chemical components, called cannabinoids, and its widespread use and abuse. The succeeding chapters deal with the first scientific meetings on marijuana, social impact of marijuana, and its widespread use in some countries, such as in Morocco and Egypt. These topics are followed by discussions on the immunological and DNA effects of marijuana. The remaining chapters highlight the legal issues and government policies concerning the utility of this plant.

Related subjects

Analytic forensic toxicology

Carcinogenic and genetic toxicology

Cardiovascular toxicology

Hepatic gastrointestinal toxicology

Immunotoxicology

Metal toxicology

Neurobehavioral toxicology

Occupational toxicology

Pesticide toxicology

Plant and animal toxins

Radiation toxicology

Regulatory toxicology

Renal toxicology

Reproductive endocrine toxicology

Respiratory toxicology

Risk assessment

Solvent and vapor toxicology

Toxicology environmental

Toxicology general

Toxicology principles

Toxicology testing and evaluation