Journals in Toxicology
Journals in Toxicology
Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.
- ISSN: 1056-8719
Journal of Pharmacological and Toxicological Methods
The Journal of Pharmacological and Toxicological Methods publishes original articles and reviews on methods for use in pharmacology and toxicology (including safety pharmacology). We are particularly interested in papers that focus on one or more of the following issues:New models of disease and approaches to drug discoveryValidation of modelsImprovement in the efficiency of techniques and assaysIdentification and mitigation against sources of experimental variationInterspecie... comparisonsStatistic... methodsNew technology for evaluation of drug activity (e.g. Including advances in imaging, imaging technology)New techniques for discovery of biologics (e.g. Immunotherapy)Non-bi... assay methodsBenefits to authors We also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services .Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our Support Center
- ISSN: 1567-5769
International Immunopharmacology
International Immunopharmacology is the primary vehicle for the publication of original research papers pertinent to the overlapping areas of immunology, pharmacology, cytokine biology, immunotherapy, immunopathology and immunotoxicology. Review articles that encompass these subjects are also welcome.The subject material appropriate for submission includes: • Clinical studies employing immunotherapy of any type including the use of: bacterial and chemical agents; thymic hormones, interferon, lymphokines, etc., in transplantation and diseases such as cancer, immunodeficiency, chronic infection and allergic, inflammatory or autoimmune disorders. • Studies on the mechanisms of action of these agents for specific parameters of immune competence as well as the overall clinical state. • Pre-clinical animal studies and in vitro studies on mechanisms of action with immunopotentiators, immunomodulators, immunoadjuvants and other pharmacological agents active on cells participating in immune or allergic responses. • Pharmacological compounds, microbial products and toxicological agents that affect the lymphoid system, and their mechanisms of action. • Agents that activate genes or modify transcription and translation within the immune response. • Substances activated, generated, or released through immunologic or related pathways that are pharmacologically active. • Production, function and regulation of cytokines and their receptors. • Classical pharmacological studies on the effects of chemokines and bioactive factors released during immunological reactions. • Studies on the nature and function of drug and hormone receptors on lymphocytes and other cells in the immune system.• Studies of cell-derived or humoral factors that modify the immune system causing cytotoxicity, inducing antibody production and mediating inflammatory responses. • The development of immunologically based assays and their application to disease, including assays for drugs, hormones, cyclic nucleotides, tumor antigens, etc. • The Editors will be pleased to receive published books for possible independent review.Please Bookmark this URL: https://www.elsevier... These Backfiles include Immunopharmacology and the International Journal of Immunopharmacology .International Immunopharmacology does not accept submissions that consist primarily of bioinformatics or computational analyses of public genomic or transcriptomic databases, unless they are supported by experimental studies involving cells, organoids, or experimental animals.
- ISSN: 0378-4274
Toxicology Letters
Official Journal of EUROTOXAffiliated with Austrian Society of ToxicologyAn international journal for the rapid publication of novel reports on a range of aspects of toxicology, especially mechanisms of toxicity.Toxicology Letters serves as a multidisciplinary forum for research in toxicology. The prime aim is the rapid publication of research studies that are both novel and advance our understanding of a particular area. In addition to hypothesis-driven studies on mechanisms of mammalian toxicity, Toxicology Letters welcomes seminal work in the following areas:In silico toxicologyToxicokine... pharmacokinetic (PBPK) modelingSystems toxicologyPredictive toxicology3R research in toxicologyNew approach methodology (NAMs)Adverse outcome pathways (AOPs)Integrated testing strategiesSystematic and narrative reviews and mini-reviews in various areas of toxicology will be published. Clinical, occupational and safety evaluation, hazard and risk assessment, regulatory toxicology, impact on man, animal and environment studies of sufficient novelty to warrant rapid publication will be considered. Toxicology Letters also publishes editorials, commentaries and contemporary issues in toxicology.The following types of work are not within the scopes of Toxicology Letters:Ecotoxicolog... studiesCase studiesChemopreventi... studiesPharmacologic... investigationsAuthor... are advised to follow the ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments; https://arriveguidel... and the OECD guidance document on Good In Vitro Method Practices (GIVIMP; https://www.oecd.org... In vitro or in vivo investigations conducted at concentrations or doses of no relevance to human or animal exposure will not be considered. Routes of exposure other than those relevant to human or animal exposure need to be justified. Assessment of dose-response should be an integral component of any toxicological research report. Unless adequately justified, studies conducted at a single dose level may not be considered. Test materials must be chemically defined and characterized. Investigations of chemically undefined plant extracts or uncharacterized nanoparticles will not be considered.
- ISSN: 0890-6238
Reproductive Toxicology
Reproductive Toxicology is affiliated with the European Teratology SocietyDrawing from a large number of disciplines, Reproductive Toxicology publishes timely, original research on the influence of chemical and physical agents on reproduction. Written by and for obstetricians, pediatricians, embryologists, teratologists, geneticists, toxicologists, andrologists, and others interested in detecting potential reproductive hazards, the journal is a forum for communication among researchers and practitioners. Articles focus on the application of in vitro, animal and clinical research to the practice of clinical medicine.All aspects of reproduction are within the scope of Reproductive Toxicology, including the formation and maturation of male and female gametes, sexual function, the events surrounding the fusion of gametes and the development of the fertilized ovum, nourishment and transport of the conceptus within the genital tract, implantation, embryogenesis, intrauterine growth, placentation and placental function, parturition, lactation and neonatal survival.Adverse reproductive effects in males will be considered as significant as adverse effects occurring in females. To provide a balanced presentation of approaches, equal emphasis will be given to clinical and animal or in vitro work.Typical end points that will be studied by contributors include:InfertilityS... dysfunctionSpontaneo... abortionMalformation... histogenesisStillbir... growth retardationPrematuri... abnormalitiesPerinat... mortality
- ISSN: 1532-0456
Comparative Biochemistry and Physiology - Part C: Toxicology & Pharmacology
Comparative Biochemistry & Physiology (CBP) publishes papers in comparative, environmental and evolutionary physiology.Part C: Toxicology and Pharmacology (CBPC), focuses on toxicological mechanisms at different levels of organization, primarily chemical and drug action, biotransformation of xenobiotics, endocrine disruptors, nanoparticles, pharmaceuticals, and natural products chemistry. Most studies employ a molecular approach in combination with observations of higher levels of organization to assess the mechanism by which xenobiotics affect physiology. Analytical verification of exposure concentrations is strongly recommended for manuscripts reporting toxicological studies.All four CBP journals support and follow the editorial direction from all the major societies in the field:Australia & New Zealand Society of Comparative Physiology and Biochemistry (ANZSCPB)American Physiological Society (APS)Canadian Society of Zoologists (CSZ)Deutsche Zoologische Gesellschaft (DZG)European Society of Comparative Physiology and Biochemistry (ESCPB)Japanese Society for Comparative Physiology and Biochemistry (JSCPB)South American Society for Comparative Physiology and Biochemistry (SASCPB)Societe de Physiologie (SDP)Society for Experimental Biology (SEB)Society for Integrative & Comparative Biology (SICB)Benefits to authorsCBP journals are focused on promoting the authors and the work published in the journal:All articles are carefully evaluated directly by the Editors-in-Chief who are leading experts in their field.Availability: contact the Editor-in-Chief for any questions you may have.The Journal will provide upon request free PDFs to all authors who may not have access to their articles via their institution or library.Publication is free to authors (no color or page charges).Supporting open access: if your funding body or institution requires your article to be open access, CBP offers that option. Please see details here.Reuse figures from any CBP article via "get rights and content" hyperlink available within each article (below author names and affiliations) on ScienceDirect.Please click here for more information on more general author services.Other CBP journals Part A (CBPA): Molecular & Integrative Physiology Part B (CBPB): Biochemistry & Molecular Biology Part D (CBPD): Genomics & Proteomics
- ISSN: 0166-445X
Aquatic Toxicology
Aquatic Toxicology publishes significant contributions that increase the understanding of the impact of harmful substances (including natural and synthetic chemicals) on aquatic organisms and ecosystems. Aquatic Toxicology considers both laboratory and field studies with a focus on freshwater/marine environments. The journal strives to attract high quality original scientific papers, critical reviews and expert opinion papers in the following areas: Effects of harmful substances on molecular, cellular, sub-organismal, organismal, population, community, and ecosystem level; Mechanisms of toxicity; Genetic disturbances, transgenerational effects, behavioral and adaptive responses; Impacts of harmful substances on structure, function of and services provided by aquatic ecosystems; Mixture and multiple toxicity assessment; Acute and chronic exposure; Environmental realistic scenarios; Impact of emerging substances and environmental pollutants of high actuality; Statistic... approaches to predict exposure to and hazards of contaminants. The journal also considers manuscripts in other areas, such as the development of innovative concepts, approaches, and methodologies, which promote the wider application of toxicological datasets to the protection of aquatic environments and inform ecological risk assessments and decision making by relevant authorities. Aquati... Toxicology does not publish articles that focus on the health of aquaculture organisms associated with aquaculture practices, unless these studies enhance our understanding of the potential effects of chemical stressors associated with aquaculture (e.g. pesticides use, water quality degradation) on aquatic organisms and/or ecosystems. Aquatic Toxicology does not consider articles that focus on monitoring the presence of chemicals in the environment unless these studies further investigate the impacts of the chemicals on aquatic organisms and/or ecological systems. Furthermore, studies that characterize the potential risks of contaminated fish or other aquatic food products on humans or livestock are outside of the scope of the journal.
- ISSN: 0891-5849
Free Radical Biology & Medicine
An official JOURNAL of the Society for Redox Biology and Medicine and the Society for Free Radical Research-Europe; affiliate journal of the International Society for Free Radical Research (SFRRI)Free Radical Biology and Medicine is the premier forum for publishing ground-breaking research in the redox biology of both health and disease. We focus on signal transduction and redox signaling; oxidative stress; reductive stress; redox stress; nitrosative stress; aging and age-related diseases; redox biology in skeletal and cardiac muscle, exercise science, and sports medicine; metabolic regulation and metabolic diseases; mitochondrial function and signaling; homeostatic mechanisms and adaptive responses; redox chemistry and mechanisms; materials and nanomaterials; non-thermal plasmas; microorganisms, fungi, plants, insects, animals, and humans; and antioxidant enzymes, pathways, and networks. We welcome both full-length and short Research Communications, Hypothesis Papers, Reviews, Mini Reviews, Graphical Reviews, and Critical Methods Papers. Free Radical Biology and Medicine also commissions themed Special Issues aimed at highlighting recent advances in both basic and clinical fields, with a particular focus on mechanisms underlying altered metabolism and redox signalling.
- ISSN: 0041-0101
Toxicon
Toxicon is affiliated with The Brazilian Society of Toxinology, The International Society on Toxinology and The North American Society of Toxinology.Toxicon is dedicated to all areas related to natural toxins and publishes peer-reviewed manuscripts describing novel findings of broad interest and importance to the toxinology community.Articles that further the understanding and knowledge of toxinology are particularly welcomed, as are review articles on toxinology. Submissions on Toxinology, Pharmacology, Immunology, Biochemistry, Health, Genetics and Molecular Biology (General) are particularly welcomed.The journal publishes articles on the following topics:original research on toxins derived from animals, plants or microorganismsnovel findings related to the chemical, pharmacological, toxicological or immunological properties of natural toxinsmolecular biological studies of toxins and related genes from poisonous and venomous organisms that advance understanding of the role or function of toxinsthe use of toxins as tools in studying biological processesthe translational application of toxins, for example as pharmacological tools, drugs or insecticidesvenom and antivenom issuesclinical observations on poisoning and envenoming where a new therapeutic principle has been proposed or a decidedly superior clinical result has been obtainedepidemiologi... studies on envenoming or poisoning, provided they highlight a previously unrecognized medical problem or provide insight into the prevention or medical treatment of envenoming or poisoningproperly designed prospective community-based surveysToxicon does not accept submissions on: - Retrospective surveys of hospital records, unless species identification is rigorous and the quality of hospital records high. Properly designed prospective clinical studies or community-based surveys are strongly encouraged.- Articles describing activities of venoms or extracts, for example antibacterial, anticancer or analgesic activities, without any attempt to define the mechanism of action or purify the active component.- Bibliometric studies, unless they include a critical evaluation of the field.
- ISSN: 0278-6915
Food and Chemical Toxicology
Affiliated with the Chinese Society of ToxicologyFood and Chemical Toxicology (FCT) is an internationally renowned journal that publishes original research articles and reviews on toxic effects and toxic mechanisms of natural or synthetic chemicals occurring in the human environment (present in food and/or the human environment). The scope of the journal includes drugs, consumer chemicals/products (e.g. cosmetics); agricultural chemicals/products (e.g. pesticides) and industrial chemicals (e.g relevant to occupational exposure). Areas such as safety evaluation of novel foods and ingredients, biotechnologically-d... products and nanomaterials are included in the scope of the journal. In these cases, a comprehensive characterisation of the materials under evaluation is necessary. FCT also encourages submission of papers on inter-relationships between nutrition and toxicology and on in vitro techniques, particularly those fostering the 3 Rs.In addition, the journal also publishes Special Issues focussed on selected subject areas. These issues typically involve new areas of interest or concern and there will be some flexibility in the papers considered in terms of scope.The principal aim of the journal is to publish high impact, scholarly work and to serve as a multidisciplinary forum for research in Toxicology. Papers submitted will be judged on the basis of scientific originality and contribution to the field, quality and subject matter.Contributors who do not heed the requirements outlined in the instructions to authors and Editorials risk manuscript rejection without further consideration.Studie... should address at least one of the following:Adverse physiological/bioche... or pathological changes induced by specific defined substances,New techniques for assessing potential toxicity,Mechanisms underlying toxic phenomena,Toxicologi... examinations of specific chemicals or consumer products, both those showing adverse effects and those demonstrating safety, that meet current standards of scientific acceptability.Author... must clearly and briefly identify what novel toxic effect (s) or toxic mechanism (s) of the chemical are being reported and what their significance is in the abstract.Studies that consider time- and dose-response effects are likely to be considered more reliable and therefore considered more favourably.Manuscrip... describing research involving the following areas will not be considered:materials... of only local interest,materials/s... for which the chemical composition is not clearly defined,only pharmacological properties or potentially beneficial effects, chemical analyses of toxins in foods without addressing the toxic implication to humans [i.e. a risk assessment should be included],unrealisti... human doses, inappropriate route(s) of exposure, or in vitro experiments that do not reflect serum levels in humans without a compelling justification.FCT is committed to the highest standards. Only papers that have not been previously published, that fit in the above-mentioned scope, and which have been reviewed by experts in the field prior to publication will be considered for eventual publication. Cover letters must be included and state that the manuscript is new and original and not under consideration for publication elsewhere. Co-authors should be individuals who have contributed substantially to the content of the papers. All authors must declare any potential conflict of interest and all financial support.Any papers offered re-submission after review must contain a separate letter containing a response to all the points raised by the Editors and reviewers.
- ISSN: 0887-2333
Toxicology in Vitro
Affiliated with the American Association for Cellular and Computational Toxicology and the European Society for Toxicology in Vitro.Toxicology in Vitro publishes original research papers, reviews and workshop reports focusing on the application and use of in vitro and in silico systems for toxicological evaluations (collectively described as New Approach Methodologies (NAM)). This includes the utilisation or the development of NAMs for assessing the potential adverse effects of chemicals for human safety assessment. In vitro techniques include primary cells, tissue slices, cell lines and stem cells (adult, embryonic and induced Pluripotent cells) or subcellular preparations thereof. Our journal strongly supports the Reduction, Refinement and Replacement (3R) of animals in toxicology evaluations.This is a wide topic and thus we have certain preferences including:Developmen... of in vitro techniques and their application to research and regulatory use (i.e. 3R principle.Mechanisti... underpinning of data.Ability to translate outcome to human safety assessment.We strongly encourage :The use of normal (non-transformed) human cells (where appropriate).Reporti... the Short Tandem Repeat (STR) profile of the cells used (especially when cells have been provided as a gift or generated in house).Free access to raw (or primary) data.Appropriate model characterisation.The use (or reduction) of animal free components, including serum. [Especially when the system was already developed under such conditions, such as the HK-2 cell line].Attention to detailed methodology and appropriate statistics. [Readers need to know how you did the experiment, how many times, how many replicates etc?]Reporting the source of the compounded tested, catalogue no. and lot no. Where the chemical has been purified or synthesised a full analytical report is expected.Quantificat... of compounds in exposure medium and/or cells over time (biokinetics).We do not accept solely in vivo investigations and rarely accept animal in vivo, in vitro hybrid papers, except where the animal data was critical in the interpretation or validation of the in vitro data (and not merely confirmatory).We generally discourage investigations relating:Unidentifie... mixtures - for example in plant extracts.Solely pharmacological investigations (e.g. demonstrating your chemical kills cancer cells in vitro is not generally acceptable).Use of non-human cells when human equivalents exist and are available.The lack of adherence to established protocols, without direct explanation.Reportin... cytotoxicity alone, with no mechanistic underpinning and/or no estimation of chemical exposure.