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Elsevier

Books in Regulatory toxicology

Supporting policymakers and industry, this portfolio emphasizes safety testing, risk assessment, and compliance standards. It features regulatory frameworks, guidelines, and case studies to ensure chemical safety and public health protection.

  • PFAS Contamination

    Global Prevalence, Toxicological and Ecotoxicological Impacts, and Mitigation Strategies
    • 1st Edition
    • Saranya Narayanasamy + 1 more
    • English
    PFAS Contamination: Global Prevalence, Toxicological and Ecotoxicological Impacts, and Mitigation Strategies offers a comprehensive overview of per- and polyfluoroalkyl substances (PFAS), highlighting their global environmental prevalence, toxicological effects and health risks, and state-of-the-art remediation approaches. The book taps into the increasing recognition of PFAS as “forever chemicals” and explores the widespread contamination of these compounds in water, soil, and air along with their toxicological effects on human health and the ecosystem. It highlights advancements in detection methods as well as physicochemical, biological, and emerging remediation technologies, including plasma-based technologies, bioremediation, and advanced nanotechnology-based methods, such as plasma technology, bioremediation, and adsorption methods.Case studies illustrate successful applications, and the book examines policy frameworks, regulatory measures, and the public health impact of PFAS. This resource serves as a vital source of information for environmental toxicologists, environmental scientists, environmental consultants, engineers, and regulators studying PFAS prevalence, toxicity mechanisms, remediation, and practical strategies for mitigating PFAS contamination and fostering a deeper understanding of the global efforts to address this critical issue.

  • Risk Management of Complex Inorganic Materials

    A Practical Guide
    • 1st Edition
    • Violaine Verougstraete
    • English
    Risk Management of Complex Inorganic Materials: A Practical Guide facilitates the risk assessment and management of complex inorganic materials around the world by providing accessible and specific guidance on their assessment. Inorganic complex materials, such as ores and concentrates, metal containing- glasses, ceramic and inorganic pigments, alloys, and UVCBs produced during the manufacturing of metals present specificities not addressed by most guidance documents. This book explains the main characteristics of inorganic complex materials affecting their hazard and risk assessment and management, including their source and main uses, also covering hazard and exposure assessment, risk characterization and risk management. It is an essential reference for regulators involved in risk assessment and risk management, industry experts charged of compliance with chemical management program requirements, consultants preparing chemicals management files for companies and regulators, and academics involved in research on complex inorganic materials.

  • Fundamentals of Toxicologic Pathology

    • 3rd Edition
    • Matthew A. Wallig + 3 more
    • English
    Fundamentals of Toxicologic Pathology, Third Edition, presents an essential overview of systems toxicologic pathology in a clear-and-concise manner. Toxicologic pathology integrates toxicology and its interdisciplinary components, including biochemistry, pharmacodynamics and risk assessment to pathology and its related disciplines, such as physiology, microbiology, immunology and molecular biology. This wholly revised and updated edition presents the newest information on the topic, and is an essential reference for advanced students, early career researchers, toxicologic pathologists, pharmaceutical scientists, medical pathologists and clinicians, and anyone involved with drug and device development. The book includes a new section describing the application of toxicologic pathology, such as diagnostic and forensic toxicologic pathology, environmental toxicologic pathology, experimental and industrial toxicologic pathology, and pathology issues in the design of toxicology studies. There are also new chapters on special senses (the eye and ear) and the biochemical and molecular basis of toxicity, among others.

  • Computational Toxicology

    Methods and Applications for Risk Assessment
    • 1st Edition
    • Bruce A. Fowler
    • English
    Computational Toxicology: Methods and Applications for Risk Assessment is an essential reference on the translation of computational toxicology data into information that can be used for more informed risk assessment decision-making. This book is authored by leading international investigators who have real-world experience in relating computational toxicology methods to risk assessment. Key topics of interest include QSAR modeling, chemical mixtures, applications to metabolomic and metabonomic data sets, toxicogenomic analyses, applications to REACH informational strategies and much more. The examples provided in this book are based on cutting-edge technologies and set out to stimulate the further development of this promising field to offer rapid, better and more cost-effective answers to major public health concerns.