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Fundamentals of Toxicologic Pathology
- 3rd Edition - October 24, 2017
- Editors: Matthew A. Wallig, Brad Bolon, Wanda M Haschek, Colin G. Rousseaux
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 0 9 8 4 1 - 7
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 0 9 8 4 2 - 4
Fundamentals of Toxicologic Pathology, Third Edition, presents an essential overview of systems toxicologic pathology in a clear-and-concise manner. Toxicologic pathology integrate… Read more
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Request a sales quoteFundamentals of Toxicologic Pathology, Third Edition, presents an essential overview of systems toxicologic pathology in a clear-and-concise manner. Toxicologic pathology integrates toxicology and its interdisciplinary components, including biochemistry, pharmacodynamics and risk assessment to pathology and its related disciplines, such as physiology, microbiology, immunology and molecular biology. This wholly revised and updated edition presents the newest information on the topic, and is an essential reference for advanced students, early career researchers, toxicologic pathologists, pharmaceutical scientists, medical pathologists and clinicians, and anyone involved with drug and device development.
The book includes a new section describing the application of toxicologic pathology, such as diagnostic and forensic toxicologic pathology, environmental toxicologic pathology, experimental and industrial toxicologic pathology, and pathology issues in the design of toxicology studies. There are also new chapters on special senses (the eye and ear) and the biochemical and molecular basis of toxicity, among others.
- Presents revised and updated information for each chapter on systems
- Contains expanded sections on applied toxicologic pathology
- Includes the essential information necessary to understand toxicologic pathology in an accessible language
Toxicologists, toxicologic pathologists, medical doctors, veterinary pathologists, graduate students, and those working in regulatory affairs, pharmacology, pharmacokinetics, animal models, or clinical development
1. Overview of Toxicological Pathology
Part I: Principles of Toxicologic Pathology2. Biochemical and Molecular Basis of Toxicity3. Pharmacokinetics & Toxicokinetics 4. Principles of Pharmacodynamics & Toxicodynamics5. Morphologic Manifesations of Toxic Cell Injury6. Carcinogenesis: Mechanisms and Manifestation7. Design of Studies & Risk Management in Toxicologic Pathology
Part II: Systems Toxicologic Pathology8. Hepatobiliary System9. Cardiovascular System10. Muscular System11. Urinary System12. Immune System13. Hematopoietic System14. Respiratory Tract15. Digestive Tract16. Exocrine Pancreas17. Male Reproductive System18. Female Reproductive System19. Mammary Gland20. Endocrine System21. Nervous System22. Special Senses: Ocular Sytem22b. Special Senses: Auditory System23. Skeletal System (Bone & Joint)24. Integumentary System25. Embryo, Fetus & Placenta
- No. of pages: 902
- Language: English
- Edition: 3
- Published: October 24, 2017
- Imprint: Academic Press
- Hardback ISBN: 9780128098417
- eBook ISBN: 9780128098424
MW
Matthew A. Wallig
Matthew A. Wallig, DVM, Ph.D., DACVP, is Professor Emeritus in the Department of Pathobiology, College of Veterinary Medicine, the Department of Food Science and Human Nutrition, as well as the Division of Nutritional Sciences at the University of Illinois. His research has focused on the chemoprotective properties and mechanisms of phytochemicals in the diet, in particular those in cruciferous vegetables, soy, and tomatoes. His current interests have expanded to include defining morphologic parameters for diagnostic quantitative ultrasound in pancreatitis, pancreatic and hepatic neoplasia, metastatic disease, and chronic hepatic diseases such as nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). Matt has served as an Editor for the last two editions of the Fundamentals of Toxicologic Pathology and Haschek and Rousseaux’s Handbook of Toxicologic Pathology.
Affiliations and expertise
Professor Emeritus, Department of Veterinary Pathobiology, College of Veterinary Medicine University of Illinois at Urbana-Champaign, Urbana, Illinois, USABB
Brad Bolon
Brad Bolon, DVM, MS, Ph.D., DAVCP, DABT, FATS, FIATP, FRCPath, has worked [sic] as an experimental and toxicologic pathologist in several settings: academia, a contract research organization, pharmaceutical companies (in both biomolecule and traditional small molecule settings), and private consulting. His main professional interests are the pathology of genetically engineered mice (especially embryos, fetuses, and placentas) and toxicologic neuropathology to assess the efficacy and safety of many therapeutic entities (biomolecules, cell and gene therapies, medical devices, and small molecules). He is a former President of the STP and a Member of the American College of Toxicology (ACT), British Society of Toxicological Pathology (BSTP), and European Society of Toxicologic Pathology (ESTP). Brad served as an Editor for the third edition of the Fundamentals of Toxicologic Pathology and an Associate Editor for the third edition of Haschek and Rousseaux’s Handbook of Toxicologic Pathology.
Affiliations and expertise
President and Pathologist, GEMpath, Inc., Longmont, Colorado, USAWM
Wanda M Haschek
Professor Haschek-Hock has served as president of the Society of Toxicologic Pathology and the Society of Toxicology’s Comparative and Veterinary Specialty Section, as well as Councilor of the American College of Veterinary Pathologists, board member of the American Board of Toxicology; as Associate Editor for Toxicological Sciences and for Toxicologic Pathology; as Editorial Board member for Fundamental and Applied Toxicology, Veterinary Pathology and Toxicologic Pathology. She has served as a member on the USFDA Veterinary Medicine Advisory Committee for the Center for Veterinary Medicine, the EPA’s FIFRA Science Advisory Panel, and National Academy of Sciences Committee. She currently serves on the Board of Directors of the C.L. Davis Foundation for the Advancement of Veterinary and Comparative Pathology. She was awarded the Society of Toxicologic Pathology’s Achievement Award in 2007 and the Midwest Regional Chapter – Society of Toxicology’s Kenneth DuBois Award in 2011.
Affiliations and expertise
Professor Emerita, Dept of Veterinary Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois, USACR
Colin G. Rousseaux
Colin G. Rousseaux, BVSc, Ph.D., DABT, FIATP, is also a Fellow of the Royal College of Pathology (FRCPath) and Fellow of the Academy of Toxicological Sciences (FATS). He is a Professor (Adjunct) in the Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of Ottawa, Canada. He has over 35 years of experience in comparative and toxicologic pathology with a research focus on herbal remedies, fetal development and teratology, and environmental pollutants. He has described, investigated, and evaluated numerous toxicologic pathology issues associated with pharmaceuticals, pesticides, and agrochemicals. He has served on the editorial board of Toxicologic Pathology. He is a former President of the STP. Colin served as an Editor for the three editions of the Fundamentals of Toxicologic Pathology and Haschek and Rousseaux’s Handbook of Toxicologic Pathology.
Affiliations and expertise
Adjunct Professor, Department of Pathology and Laboratory Medicine, University of Ottawa Principal, Colin Rousseaux and Associates, Canada