Skip to main content

Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

    • CNS and Behavioural Pharmacology

      • 1st Edition
      • October 22, 2013
      • M. Airaksinen
      • English
      • Hardback
        9 7 8 0 0 8 0 2 0 5 4 1 0
      • Paperback
        9 7 8 1 4 8 3 1 2 5 3 6 7
      • eBook
        9 7 8 1 4 8 3 1 5 7 7 8 8
      CNS and Behavioural Pharmacology is the third volume of the proceedings of the Sixth International Congress of Pharmacology, organized by the Finnish Pharmacological Society and held in Helsinki, Finland, on July 20-25, 1975. Contributors focus on the findings concerning the central nervous system (CNS) and on the developments in behavioral pharmacology and related areas of research. This volume has 33 chapters divided into five sections. After discussing the application of psychopharmacology to the conservation of wild animals such as ungulates, this book turns its attention to alcohol dependence and the interactions between neurotransmitters and the hypothalamic releasing hormones. The reader is methodically introduced to the pharmacology of emotive behavior, with emphasis on drug effects in mental and emotional disorders as well as the action of psychotropic drugs on emotions, motivations, and social behavior of animals. The final section is devoted to the pharmacological aspects of the cerebrospinal fluid-transport system. This section covers topics such as the metabolism of biogenic amines in the human CNS; the importance of dopamine metabolism for the clinical effects and side effects of neuroleptics; and composite transport systems for organic acids and bases in choroid plexus. This book will be of interest to scientists representing all the major areas of pharmacology, including clinical pharmacology and toxicology, as well as to internists, psychiatrists, neurologists, and anesthesiologists.
    • Pharmacological Control of Heart and Circulation

      • 1st Edition
      • October 22, 2013
      • L. Tardos + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 5 3 6 8
      • eBook
        9 7 8 1 4 8 3 1 4 7 7 8 9
      Pharmacological Control of Heart and Circulation, Volume 1, documents the proceedings of the 3rd Congress of the Hungarian Pharmacological Society held in Budapest, 1979. Because the papers published in this volume cover diverse areas of the cardiovascular field, they had to be arranged into several smaller symposia. The common thread running through these symposia is their focus on some pathological condition of the heart and circulation as well as on their control by drugs. The first symposium is devoted to the pharmacological control of the adverse effects of coronary insufficiency including disturbances in rhythm. The second symposium is dedicated to cardiac hypertrophy; to the action of cardiac hypertrophy on the sensitivity of the heart to drugs; and to the changes in the biochemical parameters of the myocardium due to cardiomegaly. The third symposium deals with hypertension and its pharmacological control. Two separate symposia are devoted to new drugs, namely the fourth symposium to the cerebrovascular activity of Cavinton—a synthetic Vinca-derivative; and the fifth to a newly developed beta-adrenergic blocking agent, Tobanum, to its anti-arrhythmic action, its effect in myocardial ischemia and in hypertension. Finally, a short symposium on serotonin and serotonin antagonists, both of great importance in cardiovascular pharmacology, is included.
    • Modulation of Neurochemical Transmission

      • 1st Edition
      • October 22, 2013
      • E. S. Vizi
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 5 4 0 5
      • eBook
        9 7 8 1 4 8 3 1 4 7 8 2 6
      Modulation of Neurochemical Transmission, Volume II, documents the proceedings of the 3rd Congress of the Hungarian Pharmacological Society held in Budapest, 1979. It provides a summary of biochemical, electrophysiological... morphological, and pharmacological findings on the modulation of transmitter release. The 45 papers contained in this volume come from the most important laboratories and the contributors are among the world's foremost experts. Key topics discussed include the presynaptic inhibition of neurotransmitters; the properties of pre- and postsynaptic α receptors; histochemical mapping of dopamine neurons in the olfactory brain; neurophysiological aspects of dopaminergic supersensitivity; the role of ATPases in neurochemical transmission; and interaction between noradrenaline and vanadium on brain membrane ATPase. Also presented are papers on neurotransmission in the rat portal vein; the function of cysteine metabolism in rat brain; presynaptic dopamine receptors in sympathetic heart nerves of cats; LSD-induced behavioral effects in rats; and modulation of posttetanic response in the guinea-pig ileum.
    • Epidemiology of Leukaemia and Lymphoma

      • 1st Edition
      • October 22, 2013
      • M. F. Greaves + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 8 6 1 1
      • eBook
        9 7 8 1 4 8 3 1 5 1 0 3 8
      Epidemiology of Leukaemia and Lymphoma contains the proceedings of the Leukaemia Research Fund International Workshop held in Oxford, UK, on September 25-27, 1984. Contributors explore the epidemiology of leukemia and lymphoma based on the results of a pilot study that investigated whether careful subdivision of acute lymphoblastic leukemia (ALL) using a standardized panel of monoclonal antibodies would reveal interesting associations between subtypes and particular geographic regions or ethnic groups within regions. This book is comprised of 31 chapters divided into four sections and begins with a discussion on epidemiological approaches to hematological malignancy, paying particular attention to international data collection and interpretation; clusters and associations in cancer epidemiology; and childhood leukemia in Great Britain and the Netherlands. The next section explores the causes of human leukemia and lymphoma as well as the epidemiology of leukemia and lymphoma subtypes in various regions of the world such as Africa, Asia, United States, and Mediterranean region. The final section focuses on practical problems in standardized immunophenotyping of leukemias and lymphomas; immuno-alkaline phosphatase labeling of hematological samples; and detection of surface membrane antigens by a rosette assay using antibody coupled red cells. This monograph will be of value to clinicians and medical practitioners interested in the epidemiology of leukemia and lymphoma.
    • Algal and Fungal Toxins

      • 1st Edition
      • October 22, 2013
      • Solomon Kadis + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 0 4 6 5 0 7 1
      • Paperback
        9 7 8 1 4 8 3 2 3 5 3 8 7
      • eBook
        9 7 8 1 4 8 3 2 5 9 4 8 2
      Microbial Toxins, Volume VII: Algal and Fungal Toxins reviews research and investigations on algal and fungal toxins. This book discusses the distribution of poisonous dinoflagellates; pharmacology of blue-green algal toxins; control of Prymnesium and detection of toxin in nature; and F-2 (zearalenone) estrogenic mycotoxin from Fusarium. The effect of Fusarium toxins in animals; mycotoxins produced by Fusarium tricinctum NRRL 3249; and mold growth and production and isolation of trichothecenes are also elaborated. This publication likewise covers the chemistry of scirpene toxic substances of Fusarium nivale; isolation of salivation factor; and mammalian toxicity of epidithiadioxopipera... This volume is a useful reference for scientists and graduate students in various disciplines —microbiology, biochemistry, pharmacology, epidemiology, oncology, and related fields.
    • Essays in Toxicology

      • 1st Edition
      • October 22, 2013
      • Frank R. Blood
      • English
      • Paperback
        9 7 8 0 1 2 1 0 7 6 5 1 1
      • eBook
        9 7 8 1 4 8 3 2 1 3 9 6 5
      Essays in Toxicology, Volume 1 covers essays in toxicology and related topics. The book presents essays on the use of poisons as tools in studying the nervous system as well as teratology. The text also includes essays on the significance of methemoglobinemia in toxicology and lead poisoning. Biochemists, plant and animal physiologists, pharmacologists, pathologists, microbiologists, entomologists, food technologist, and people involved in forensic medicine and industrial medicine.
    • Herbal Simples

      • 2nd Edition
      • October 22, 2013
      • W. T. Fernie
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 8 4 0 4
      • eBook
        9 7 8 1 4 8 3 2 2 1 8 3 0
      Herbal Simples Approved for Modern Uses of Cure, Second Edition considers the medical nature of herbal simples based on accurate and precise chemical analysis. This book examines the positive remedial actions of numerous herbal plants in terms of their chemical constituents and their curing capacity. Leading herbal simples are reviewed alphabetically, and to ensure accuracy, the genus and species of each plant are particularized. This text reconsiders those safe and sound herbal curative remedies and medicine that were formerly most in vogue as homely simples, whether to be taken or to be outwardly applied. The issue of whether the herbal simples be employed as auxiliaries by the physician in attendance or are welcomed for prompt service in a household emergency is discussed. This book will be of great value to biologists, herbalists, and research workers in the fields related to herbal medicines.
    • Advances in Pharmacological Research and Practice

      • 1st Edition
      • October 22, 2013
      • J. Knoll + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 5 5 9 7
      • eBook
        9 7 8 1 4 8 3 1 4 8 0 1 4
      Advances in Pharmacological Research and Practice, Volume 1: Pharmacological Protection of the Myocardium presents the proceedings of the 4th Congress of the Hungarian Pharmacological Society, held in Budapest, Hungary in 1985. This book presents a comprehensive view of the development in the fields of pharmacological protection of the myocardium and the pharmacology of the vascular system. Organized into two sections encompassing 70 chapters, this volume begins with an overview of the ischemic biochemical changes with emphasis on the role of cAMP and the protein kinase system. This text then explores the cellular electrophysiological disorders seen in acute myocardial ischemia as well as their pharmacological modification. Other chapters consider the prevention of primary ventricular fibrillation that includes measures aimed at maintaining electrical stability. The final chapter deals with drugs affecting beneficially the pathological lipoprotein levels. This book is a valuable resource for cardiologists and pharmacologists.
    • Anabolic Steroids

      • 1st Edition
      • October 22, 2013
      • H.-L. Krüskemper
      • English
      • Paperback
        9 7 8 1 4 8 3 2 5 4 5 1 7
      • Hardback
        9 7 8 1 4 8 3 2 3 1 2 6 6
      • eBook
        9 7 8 1 4 8 3 2 6 5 0 4 9
      Anabolic Steroids attempts to trace the development of anabolic steroids in the chemical, experimental biological, and clinical disciplines, and presents a precise outline of the current state of substantiated knowledge. This book deals with anabolic steroids derived from natural androgens and characterized by their stimulatory action on the biosynthesis of tissue protein and by their simultaneous low androgenicity. The biochemical part is a review of substantiated and current knowledge based largely on experimental results with animals, while the clinical part attempts to bring out the pathophysiological rationale of therapy with anabolic steroids, again based on experimental data. The book begins with a discussion of the nomenclature and chemistry of anabolic steroids. This is followed by separate chapters on the metabolism, activities, and mechanism of action of anabolic steroids; clinical application of anabolic steroids, side effects, and test procedures.
    • The Actions and Uses of Ophthalmic Drugs

      • 3rd Edition
      • October 22, 2013
      • P. H. O'Connor Davies + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 6 2 3 9
      • eBook
        9 7 8 1 4 8 3 1 9 2 0 4 8
      The Actions and Uses of Ophthalmic Drugs, Third Edition discuses the application and discrimination in the use of ophthalmic drugs. The book reviews the general pharmacological principles including drug nomenclature, pharmacological classification, pharmacokinetics, pharmacodynamics, and the use of these drugs. Ophthalmic drugs (cycloplegics, mydriatics, miotics) directly or indirectly, stimulate or inhibit a part of the autonomic nervous system connected to the intra-ocular muscles. The text investigates in detail the structure and function of this involuntary nervous system in the orbital region as it is affected by these drugs. The book explains the different drug classifications, their therapeutic and diagnostic purposes, including the ideal properties, indications, contra-indications, mode of action, or adverse effects of cycloplegics, of mydriatics, and of miotics. The book also describes the uses and characteristics of local anesthetics, stains, anti-infective agents, and miscellaneous agents (antihistamines, vasoconstrictors). The text explains the different types of contact lens solutions, application of ocular first aid, as well as, the possible adverse ocular reactions that can occur during ophthalmic drug therapy. This book is suitable for optometrists, pharmacists, pharmacologists, students and professors related to the discipline of optometry and general medicine.