Advances in Pharmacological Research and Practice
Proceedings of the 4th Congress of the Hungarian Pharmacological Society, Budapest, 1985
- 1st Edition - January 1, 1986
- Imprint: Pergamon
- Editors: J. Knoll, K. Kelemen
- Language: English
- Paperback ISBN:9 7 8 - 1 - 4 8 3 1 - 1 5 5 9 - 7
- eBook ISBN:9 7 8 - 1 - 4 8 3 1 - 4 8 0 1 - 4
Advances in Pharmacological Research and Practice, Volume 1: Pharmacological Protection of the Myocardium presents the proceedings of the 4th Congress of the Hungarian… Read more
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Request a sales quoteAdvances in Pharmacological Research and Practice, Volume 1: Pharmacological Protection of the Myocardium presents the proceedings of the 4th Congress of the Hungarian Pharmacological Society, held in Budapest, Hungary in 1985. This book presents a comprehensive view of the development in the fields of pharmacological protection of the myocardium and the pharmacology of the vascular system. Organized into two sections encompassing 70 chapters, this volume begins with an overview of the ischemic biochemical changes with emphasis on the role of cAMP and the protein kinase system. This text then explores the cellular electrophysiological disorders seen in acute myocardial ischemia as well as their pharmacological modification. Other chapters consider the prevention of primary ventricular fibrillation that includes measures aimed at maintaining electrical stability. The final chapter deals with drugs affecting beneficially the pathological lipoprotein levels. This book is a valuable resource for cardiologists and pharmacologists.
Preface
Section 1 Pharmacological Protection of the Myocardium
Introduction
The Cyclic AMP-Protein Kinase System in Acute Myocardial Ischaemia
Cellular Electrophysiological Disorders in Acute Myocardial Ischaemia and their Modification by Drugs
Antiarrhythmic Effects of Possible Anti-Ischemic Drugs
Protection of the Ischaemic Heart. Prevention of Primary Ventricular Fibrillation
Reflections on the Mode of Action of Beta-Adrenoceptor Antagonists in Prolonging Life After Acute Myocardial Infarction
Cardioprotective and Cerebroprotective Effect of Lipocortin-Like Substances
Antiischaemic Actions of Calcium Antagonists
Cardio-Protective and Nonprotective Effects of Drugs During Anoxia and Reoxygenation
Cardiac Glycosides and Myocardial Ischaemia
Pharmacological Control of Thrombotic Processes for Prevention of Myocardial Ischaemia
The Pharmacological Protection of the Ischaemic Myocardium. Problems and Possibilities
Ethacizine: Antiarrhythmic and Antiischaemic Properties
Effects of Diltiazem and Verapamil in a New Canine Model of Myocardial Infarction
Possible Differences Among the Drug-Induced Responses of the Descending and Circumflex Coronary Arteries in the Anaesthetized Dog
Beta-Adrenolytic Withdrawal Rebound Phenomenon: An Introduction
A Contribution to the Mechanism of Beta-Adrenolytic Withdrawal Syndrome
Alterations in the Efficacy of Beta-Adrenotropic Drugs Due to Changes in the Tone of the Autonomic Nervous System
Arteriovenous Difference in the Inhibition of Platelet Aggregation by the Antianginal Drug: Ch-102
Inhibition of Adenylate Cyclase by Ca2+ in the Ischaemic Myocardium. A Concept of Protection by Ca2+ Channel and β-Blockade
Protective Effect of Calcium Antagonists on Ischaemic Myocardial Metabolism Due to Vasopressin Induced Coronary Spasm
Inhibition of cAMP-Phosphodiesterase from Heart and Coronary Arteries by a New Trapidil Derivative
Comparison of Three Calcium Antagonists, Verapamil, Diltiazem and Fendiline on the Energetic State of Isolated Langendorff Rat Heart
Effect of IS, a Water Soluble Derivative of Indomethacin, on the Outcome of the Very Early Phase of Experimental Myocardial Infarction in Conscious Rats
The Use of Voltage Clamp in the Testing of Antiarrhythmic Drugs
Intracellular Electrophysiological Effects of Amiodarone After Acute and Chronic Application in Guinea Pig Ventricular and Dog Purkinje Fibers
Electrical and Mechanical Activity of the Myocardium as Affected by CH-101, an Antiarrhythmic Agent with Preferential Supraventricular Action
Involvement of the Central Nicotinic Receptors in the Genesis of the Centrogenic Cardiac Arrhythmias in the Rats
Morphine and Tifluadom-Induced Centrogenic Arrhythmias in Anaesthetized Rats
Structure — Antiarrhythmic Activity Relationship of the Amino-Alcohol Derivatives
Long Term Treatment of Cardiac Arrhythmias with Nadolol
Electrophysiological Bases of Antifibrillatory Action of Chinoin-103
Microelectrophysiological Procedure for the Analysis of Drug Effects on the Atrioventricular Conducting System
Serum Levels of Digoxin During Combined Treatment with Digoxin and Amiodarone
The Inotropic Effect of Isoproterenol and Dopamine Under Different Levels of Oxygenation
The Influence of Doxorubicin Combined with Other Drugs on Haemodynamic Parameters in Rabbits
New Antiarrhythmic Agent with Positive Cardiac Actions(GYKI-38 233)
Cardiac Electrophysiological Effects of Lysolecithin, an Ischaemic Metabolite, on Rabbit Atrial and Ventricular Myocardium
Acute and Chronic Effects of Ipratropium Bromide (ITROP) in Patients with Bradycardia
Myocardial Protection by Computerised Long-Time Controlling of the Myocardial Glucose-, Insulin-, Fatty Acid-Supply in Man
List of Contributors
Subject Index
Section 2 Pharmacological Protection of the Vascular System
Chemical and Biochemical Parameters Associated with New Cardiovascular Drugs
Role of Adenosine Receptors
Interactions Between Effects of Adenosine and Inosine in the Coronary Circulation: A New Hypothesis of Metabolic Autoregulation
A Pharmacological Approach to Adenosine Receptors in Myocardium, Sinoatrial Node and Vascular Smooth Muscle
Central Mechanisms and Actions in Hypertension
Adrenergic-Opioid Interactions in Central Cardiovascular and Pain Control
Beta-Endorphin and Antihypertensive Drugs
The Responsiveness of Alpha2-Adrenoceptors in Some Brain Regions of Spontaneous and Vasopressin Hypertensive Rats
Interference of Blood Pressure Variation with the Effect of Antihypertensive Drugs in Normotensive Monkeys Macaca Mulatta
The influence of GABA-ergic System - A New Way in Prophylaxis and Treatment of Hypertension in Experiment
Haemodynamic Interactions Between Guanfacine and Endrallazine in Hypertensive Patients
Role of Calcium Antagonists and Influence of Calcium Fluxes
Role of Calcium Antagonists in the Treatment of Hypertension
The Effect of Calcium Channel Blockers on the Release of Tritiated Noradrenaline from the Pulmonary Artery of Rabbit
Blood Pressure Lowering Effect of Nifedipine: Its Relationship with Exchangeable Body Sodium
Analysis of the Calcium Channel Blockers
Comparative Cardiovascular Effects of Prazosin and Verapamil
Drug Interactions on the Smooth Muscles of the Isolated Spirally Cut Strip of Rat Aorta
Effects of Isoquinoline Derivatives on Cyclic Nucleotides and Calcium Fluxes in Rat Blood Vessels
Role of Vasodilators
Report on the Pharmacological Effects of Three New Peripheral Vasodilator Compounds RGH-0537, RGH-2981 and RGH-2970
Hemodynamic Effects of Vasodilators on Peripheral Circulation
The Influence of Amezinium on Regulation of Arterial Pressure
Circulatory Effects of Fusaric Acid Derivatives
Pharmacological Investigations of the CH-141, a New Isoquinolyl-Oxadiazine Derivative
Role of Alpha-And Beta-Adrenergic and 5-HT Receptors
Regulation of Alpha-Adrenergic Receptors in Dogs' Myocardium and the Coronary Artery
The Effects of Pentacaine and Related Local Anaesthetics on Beta-Adrenergic Receptors and Adenylate Cyclase Activity in Turkey Erythrocyte and Rat Liver Membranes
A Contribution to the Mechanism of Beta-Adrenolytic Withdrawal Syndrome
The Effect of Beta-Adrenoceptor Blocking Drugs on Platelet Aggregation, Calcium Displacement and Fluidization of the Membrane
Effects of Tobanum and Propranolol on Platelet Aggregation Ex Vivo
Interaction of Dihydroergotamine with 5-HT Receptors on Human Blood Platelets and Femoral Veins
Effects of Forskolin, Trequinsine and Isoproterenol on Norepinephrine -Induced Contractions, cAMP and cGMP Levels of Isolated Vascular Tissue
Actions on the Pulmonary Artery
Ouabain Evoked 3(H)-Noradrenaline Release from the Main Pulmonary Artery of the Rabbit
Pharmacological Actions and the Pulmonary Circulation
Influence of the Lipoprotein Level
Effect of a New Benzhydrole Derivative (RGH-2801) on the Lipoprotein and LCAT Level
List of Contributors
Subject Index
- Edition: 1
- Published: January 1, 1986
- No. of pages (eBook): 432
- Imprint: Pergamon
- Language: English
- Paperback ISBN: 9781483115597
- eBook ISBN: 9781483148014
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