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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

BooksJournals

    • Hemodynamics and Immune Defense

      • 2nd Edition
      • October 23, 2023
      • Michael J. Parnham + 2 more
      • English
      • Hardback
        9 7 8 0 3 2 3 9 9 3 1 8 0
      • eBook
        9 7 8 0 3 2 3 9 9 3 1 9 7
      Haemodynamics and Immune Defence: Discoveries in Pharmacology, Second Edition, Volume Three presents selected articles from the historic Discoveries in Pharmacology series that are enhanced with commentary from contemporary scholars who discuss the reception and importance of each chapter along with an updated bibliography on the subject and contributions from those involved in Nobel Prize winning discoveries and pioneering advancements in Pharmacology. This volume brings forth discussions on key discoveries in hemodynamics and immune defense, including chapters on penicillin by Dr. Selwyn and asthma by Dr. Brocklehurst. Academic and industry researchers in pharmacology and medicine, as well as advanced students in the area, will find this useful teaching tool and launch to new discoveries. Chapters can also be used to supplement course material in pharmacology and medical courses. It will also be of interest to those who are interested in the history of medicine.

    • Pharmaceutical Biotechnology in Drug Development

      • 1st Edition
      • April 21, 2023
      • Muhammad Sajid Hamid Akash + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 9 1 3 5 0
      • eBook
        9 7 8 0 4 4 3 1 9 1 3 6 7
      Pharmaceutical Biotechnology in Drug Development summarizes key concepts and the latest developments of biotechnology applied to the development of biopharmaceuticals. Chapters present a comprehensive collection of introductory biotechnology technologies and their modern concepts and cover pharmacokinetic and pharmacodynamic behavior of biopharmaceuticals and modification techniques of amino acids and nucleic acid. Other sections focus on topics such as gene therapy, immunological preparations and nanoparticles which are the major contributions of pharmaceutical biotechnology. Final chapters discuss emerging techniques in the field of pharmaceutical biotechnology to meet current patient and health care demand. This book is an essential reference useful for pharmaceutical scientists, clinicians and academic researchers who want easy access to up-to-date practices of pharmaceutical biotechnology. Corporate researchers will also benefit from this book’s succinct and objective content structure.

    • Phytopharmaceuticals and Herbal Drugs

      • 1st Edition
      • July 15, 2023
      • Manju Rawat Singh + 1 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 9 1 2 5 4
      • eBook
        9 7 8 0 3 2 3 9 9 3 6 9 2
      Phytopharmaceuticals and Herbal Drugs: Prospects and Safety Issues in the Delivery of Natural Products explores the delivery aspects of plant-based drugs, providing insights into formulation constraints associated with plant-based drugs, the development of novel delivery systems based on polymers or lipids, and how combining natural products with technological advancements in drug delivery is making large strides. Some of the best-selling drugs for the treatment of diseases like cancer, ulcers and malaria are either natural products or their derivatives, all of which are covered in this comprehensive resource. This book will be useful to researchers working in plant-derived medicines and the development of their delivery systems, including sections on their derivatives and analogs that represent over 50% of all drugs in clinical use. Active ingredients originated from plant resources generally exhibit compromised desired effects limited by issues such as stability, solubility, molecular size, bioavailability and toxicity.

    • Cheminformatics, QSAR and Machine Learning Applications for Novel Drug Development

      • 1st Edition
      • May 23, 2023
      • Kunal Roy
      • English
      • Paperback
        9 7 8 0 4 4 3 1 8 6 3 8 7
      • eBook
        9 7 8 0 4 4 3 1 8 6 3 9 4
      Cheminformatics, QSAR and Machine Learning Applications for Novel Drug Development aims at showcasing different structure-based, ligand-based, and machine learning tools currently used in drug design. It also highlights special topics of computational drug design together with the available tools and databases. The integrated presentation of chemometrics, cheminformatics, and machine learning methods under is one of the strengths of the book.The first part of the content is devoted to establishing the foundations of the area. Here recent trends in computational modeling of drugs are presented. Other topics present in this part include QSAR in medicinal chemistry, structure-based methods, chemoinformatics and chemometric approaches, and machine learning methods in drug design. The second part focuses on methods and case studies including molecular descriptors, molecular similarity, structure-based based screening, homology modeling in protein structure predictions, molecular docking, stability of drug receptor interactions, deep learning and support vector machine in drug design. The third part of the book is dedicated to special topics, including dedicated chapters on topics ranging from de design of green pharmaceuticals to computational toxicology. The final part is dedicated to present the available tools and databases, including QSAR databases, free tools and databases in ligand and structure-based drug design, and machine learning resources for drug design. The final chapters discuss different web servers used for identification of various drug candidates.

    • Modulation of Oxidative Stress

      • 1st Edition
      • August 4, 2023
      • Luciano Saso + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 9 2 4 7 0
      • eBook
        9 7 8 0 4 4 3 1 9 2 4 8 7
      Modulation of Oxidative Stress: Biochemical, Physiological and Pharmacological Aspects explores the field using an interdisciplinary approach, including chemical, biological, physiological, pharmaceutical, pharmacological and physicochemical perspectives. The book is comprised of three main parts, with the first discussing the biochemical aspects of oxidative stress modulation. Other sections cover physiological and pathophysiological aspects on relevant conditions, including aging, neurological diseases, cerebral cavernous malformation, maternal and early-life malnutrition, Alzheimer’s disease, liver transplant, and cancer. Final content is dedicated to pharmacological aspects and includes chapters on phytotherapy and flavonoids. This book is a strong reference for pharma researchers in academia and industry considering leveraging modulation of oxidative stress as a strategy for the development of new drugs. Biochemists and Nutritionists may also benefit of the foundational understanding of cellular redox processes laid out.

    • Environmental Carcinogenesis

      • 1st Edition
      • Volume 96
      • February 24, 2023
      • English
      • Hardback
        9 7 8 0 3 2 3 9 9 7 7 5 1
      • eBook
        9 7 8 0 3 2 3 9 9 7 7 6 8
      Environmental Carcinogenesis, Volume 96 in the Advances in Pharmacology series, reports on work done with carcinogenic metals and the mechanisms of their carcinogenicity, including Arsenic and Chromate. Chapters in this release include Breast cancer carcinogenesis by organophosphate pesticides, Polyadenylation of Canonical histone H3.1 in Carcinogenesis, Epigenomic reprogramming in iAs-mediated carcinogenesis, MicroRNAs and epigenetic regulation in metal-induced angiogenesis and carcinogenesis, Environmental epigenetics and new mechanistic markers of chemical exposure, Arsenic carcinogenesis by inhibition of DNA repair, Genetic and environmental reprogramming of the sarcoma epigenome, Mechanism of chromate carcinogenesis by chromatin alterations, and more. Other chapters cover Arsenic carcinogenesis and microRNAs, Epigenetic mechanism of Cr(VI)-induced cell malignant transformation and tumorigenesis, The dark side of NRF2 in arsenic carcinogenesis, and Chemical mechanisms of DNA damage by carcinogenic chromium(VI).

    • Lantibiotics as Alternative Therapeutics

      • 1st Edition
      • February 17, 2023
      • Sanket Joshi + 3 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 9 1 4 1 4
      • eBook
        9 7 8 0 3 2 3 9 9 1 4 2 1
      Lantibiotics as Alternative Therapeutics explores alternative therapeutics, lantibiotics and other novel drugs. This book provides concrete information to readers regarding lantibiotics and various types of antimicrobial peptides with their mode of actions in treating various multidrug resistant organisms. It explains various techniques that are involved in analyzing antimicrobial peptides and their mode of actions. The development of antibiotic resistance has now reached a point of crisis where innovative methods and application of novel compounds and methods are required to prevent the spread of drug resistant infections. Novel compounds exhibit different modes of action to the currently used mechanism of therapeutics in order to combat against the resistant organisms. Lantibiotics hold considerable potential as a consequence of their unusual structure, unique mechanisms of action and their potency against multi-drug resistant bacteria. This book will be useful for pharmaceutical industry scientists and researchers in microbial and biomedical research as well as graduate and advanced students in microbiology, medical biotechnology, health, and pharmaceutical sciences.

    • Clinical Trials and Tribulations

      • 1st Edition
      • March 1, 2023
      • Gayathri De Lanerolle + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 7 8 7 0
      • eBook
        9 7 8 0 1 2 8 2 1 7 8 8 7
      Clinical Trials and Tribulations evaluates the multiple layers of complexities around research management, also exploring current practices, challenges and future directions. The book provides answers to readers questions and problems through extensive use of real-world examples, case studies and lessons learned. Following an approach to provide pragmatic viewpoints as well as concepts and methodologies and its alignment with specific practices, the book explores paradigms between planning and conducting research in academia vs. healthcare vs. industry in the UK vs. Europe vs. America. It highlights practical solutions to real-world complex issues that have been documented by independent regulators. This will be an indispensable book for all staff working in clinical research within healthcare, academia and industry, as well as students intending to work in clinical trials.

    • Rang & Dale's Pharmacology

      • 10th Edition
      • May 13, 2023
      • James M. Ritter + 6 more
      • English
      • Paperback
        9 7 8 0 3 2 3 8 7 3 9 5 6
      • Paperback
        9 7 8 0 3 2 3 8 7 3 9 6 3
      • eBook
        9 7 8 0 3 2 3 8 7 3 9 8 7
      Rang and Dale’s Pharmacology is internationally acknowledged as the core textbook for students of pharmacology, and has provided accessible, up-to-date information on drugs and their mechanism of action for more than 30 years.Now in its tenth edition, it has been updated to include important new drugs such as gene therapies, personalised medicines and the new wave of RNA drugs. However it has not lost any of the elements that have contributed to its popularity, such as color coding and illustrations, making it reader-friendly while comprehensively covering the depth of detail required.This essential book is recommended as the first-choice undergraduate text for science and medical students and junior doctors and will also be useful for students in other professional disciplines such as pharmacy, veterinary medicine and nursing.

    • Standardizing Pharmacology: Assays and Hormones

      • 2nd Edition
      • February 23, 2023
      • Michael J. Parnham + 2 more
      • English
      • Hardback
        9 7 8 0 3 2 3 8 5 5 1 7 4
      • eBook
        9 7 8 0 3 2 3 8 5 5 1 8 1
      Standardizing Pharmacology: Assays and Hormones, Volume Two in the Discoveries in Pharmacology series, presents selected articles from historic discoveries that are enhanced with commentary from contemporary scholars who present discussions on the importance of each chapter, along with an updated bibliography on the subject and contributions from a Nobel Prize winner and other pioneers in pharmacology. Academic and industry researchers in pharmacology and medicine, as well as advanced students will find this series a useful teaching tool and launch to new discoveries. Sections cover key discoveries in receptor theory, pharmacological methods and the development of hormone therapy, including J. Parascandola on the development of receptor theory, R.S. Yalow on radioimmunoassay, M. van Rossum and J.T L.A. Hurkmans on bioassays, M. Tausk on androgen therapy and C. Djerassi on oral contraceptives, with commentaries from experts such as T. Hökfelt and V.C. Jordan.

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