Bioactive Lipid Mediators in Cardiopulmonary Pharmacology

1st Edition, Volume 97 - May 24, 2023
Editors: Darryl C Zeldin, John Seubert
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 9 5 0 5 7 - 2
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 5 0 5 8 - 9

Bioactive Lipid Mediators in Cardiopulmonary Pharmacology, Volume 97 updates readers on topics surrounding Bioactive lipid mediators. These mediators are involved in a vast arra… Read more

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Bioactive Lipid Mediators in Cardiopulmonary Pharmacology, Volume 97 updates readers on topics surrounding Bioactive lipid mediators. These mediators are involved in a vast array of signaling pathways that regulate both physiological and pathophysiological responses. Chapters in this new release include Cyclooxygenases and Vascular Function, Cyclooxygenases and Platelet Function, Eicosanoids and Cardiomyopathies, Cytochrome P450 Bioactive Lipids in the Heart, Epoxide Hydrolase and Leukotoxin in the Heart and Lung, Role of cytochrome P450-epoxygenase and soluble epoxide hydrolase in the regulation of vascular response, Bioactive Lipids in Hypertension, Cytochrome P450 Metabolites and Angiogenesis, 20-Hydroxyeicosatetraenoic Acid and Vascular Function, and more.

Other critical sections cover Cytochrome P450 Eicosanoids and the Brain, Omega-3 Oxylipids, Resolvins, Lipoxins and Inflammation, Endocannabinoids as Bioactive Metabolites, and Oxylipins and Aspirin Exacerbated Respiratory Disease.

Darryl C Zeldin

Dr. Darryl Zeldin is a Senior Investigator and the Scientific Director at the National Institute of Environmental Health Sciences, National Institutes of Health (NIH/NIEHS). He obtained his MD degree from Indiana University School of Medicine, completed his Internship/Residency in Internal Medicine at Duke University Medical Center and his Pulmonary/Critical Care Fellowship at Vanderbilt University Medical Center. His research program focuses on understanding the role of eicosanoids in regulating pulmonary and cardiovascular function. He is a Fellow in the American College of Chest Physicians, a Fellow in the American Heart Association and is an elected member of the American Society for Clinical Investigation and American Association of Physicians. He has co-authored over 380 primary peer-reviewed articles and his work has been cited over 33,000 times. He has mentored over 85 post-baccalaureate fellows, graduate students, medical students, postdoctoral research fellows and clinical research fellows. As the NIEHS Scientific Director, he is responsible for one of the largest intramural research programs at the NIH with over 600 scientists in 11 Departments and 17 Core Facilities.

Affiliations and expertise

National Institutes of Health/National Institute of Environmental Health Services, NC, USA

John Seubert

Dr. John M. Seubert is a Professor in the Faculty of Pharmacy and Pharmaceutical Sciences at the University of Alberta. He obtained his MSc in Biological Sciences (Simon Fraser University), PhD in Pharmacology and Toxicology (University of Western Ontario) and a Postdoctoral Fellowship in Cardiovascular Pharmacology at the National Institute of Environmental Health Sciences, National Institutes of Health (NIH/NIEHS). His research program focuses on the biological role essential fatty acids have in cardiac homeostasis and pathology. A central theme involves understanding the role the cytochrome P450 system has within the cell to assist in the development novel drug targets and strategies to limit injury. He is an adjunct professor in the Department of Pharmacology, Faculty of Medicine and Dentistry at the University of Alberta. He has co-authored over 78 primary peer-reviewed articles. He has mentored over 90 undergraduate students, pharmacy students, graduate students, postdoctoral research fellows and research fellows. His research has been funded by the Heart and Stroke Foundation of Canada, Canadian Institutes of Health Research and the Natural Sciences and Engineering Research Council of Canada.

Affiliations and expertise

University of Alberta Faculty of Medicine and Dentistry, Edmonton, Canada