Neuropsychopharmacology

1st Edition - May 10, 2023
Authors: Jahangir Moini, Anthony LoGalbo, Jennifer G. Schnellmann
Language: English
Paperback ISBN:
9 7 8 - 0 - 3 2 3 - 9 5 9 7 4 - 2
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 5 9 7 3 - 5

Neuropsychopharmacology reviews the principles of pharmacology with a focus on the central nervous system and autonomic nervous system. Beyond autonomic and central nervous s… Read more

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Neuropsychopharmacology reviews the principles of pharmacology with a focus on the central nervous system and autonomic nervous system. Beyond autonomic and central nervous system pharmacology, this volume uniquely discusses psychiatric disorders and the pharmacological interventions that are available for conditions including depression, schizophrenia and anxiety disorders. With a focus on these specific body systems, readers will see end-of-chapter questions that offer real-world case studies, as well as multiple-choice questions for further learning. Beneficial features and content also include two extensive examination tests, which each contain 100 questions for better learning or to be used in teaching, and a glossary.

Helpful appendices cover high-alert medications and toxicology effects on the nervous system. Each chapter will contain classifications of medications, pharmacokinetics, mechanism of action, clinical indications and toxicities.

Cover image
Title page
Table of Contents
Copyright
Dedication
About the authors
Preface
Acknowledgments
Unit I. Principles of pharmacology
Chapter 1. Introduction
Overview
Brief history of pharmacology
Drug classification
Prototype drugs
Drug names
Chapter 2. Drug approval and drug regulations
Overview
Drug approval
Changes to the drug approval process
Brief history of drug legislation
Drug standards
The US Food and Drug Administration
Prescription writing and regulations
Over-the-counter drugs
Controlled substances
Clinical case study
Chapter 3. Pharmacokinetics
Overview
The passage of drugs through plasma membranes
Drug absorption
Drug distribution
Drug metabolism
Drug elimination
Time–response relationships
Half-life
Multiple-dose drug administration
Clinical case studies
Chapter 4. Pharmacodynamics
Overview
Therapeutic index and therapeutic window
Duration of action
Dose–response relationship
Potency and efficacy
Receptors
Receptor regulation
Agonists
Antagonists
Pharmacogenetics
Clinical case studies
Chapter 5. Pharmacogenomics, drug toxicity, and environmental toxins
Overview
Pharmacogenomics
Drug toxicity
Adverse effects
Drug toxicity of specific organs
Specific environmental toxins
Antidotes
Clinical case studies
Chapter 6. Medication errors and risk reduction
Overview
Medication errors
Sentinel events
Risk reduction
Strategies for handling medication errors
Reconciling medications
Patient education about medications
Clinical case studies
Chapter 7. Substance abuse
Overview
Substance abuse
Substance misuse
Addictive drugs
Central nervous system depressants
Cannabinoids
Hallucinogens
Central nervous system stimulants
Effects of substance abuse
Prevention and treatment for substance abuse
Cigarette smoking
Alcoholism
Clinical case studies
Chapter 8. Dietary supplements and herbal remedies
Overview
Popularity of dietary supplements
National center for complementary and alternative medicine
Dietary Supplement Health and Education Act of 1994
Common herbal remedies
Potential hazards of herbals
Clinical case studies
Unit II. Pharmacology of the central nervous system
Chapter 9. Review of the central nervous system
Overview
Neuroglia
Neurons
Neurotransmitters
Brain
Spinal cord
Chapter 10. Opioid and nonopioid analgesics
Overview
Pain receptors and pathways
Development of pain
Pain processing
Chronic pain
The emotional reaction to pain
Nonopioid analgesics
Nonsteroidal antiinflammatory drugs
Opioid analgesics
Opioid-use disorder pharmacotherapy
Clinical case studies
Chapter 11. Antiseizure drugs
Overview
Causes of seizures
Classifications of seizures
Back-up and adjunctive drugs
Clinical case studies
Chapter 12. Skeletal muscle relaxants
Overview
Musculoskeletal system
Muscle spasms and spasticity
Skeletal muscle relaxants
Clinical case studies
Chapter 13. General anesthesia
Overview
Stages of anesthesia
Classifications of medications
Methods of anesthesia
Anesthesia adjuncts
Clinical case studies
Chapter 14. Local anesthesia
Overview
Local anesthetics
Spinal anesthesia
Clinical case studies
Chapter 15. Pharmacology of Parkinson's disease
Overview
Parkinson's disease
Dopaminergics
Anticholinergics
Monoamine oxidase type B inhibitors
COMT inhibitors
Amantadine
Clinical case studies
Chapter 16. Pharmacology of Alzheimer’s disease
Overview
Alzheimer's disease
Acetylcholinesterase inhibitors
N-methyl-d-aspartate (NMDA) receptor modulators
Aducanumab
Clinical case studies
Chapter 17. Pharmacology of migraines
Overview
Classifications of migraines
Pharmacotherapy
Clinical case studies
Unit III. Introduction to autonomic pharmacology
Chapter 18. Review of the autonomic nervous system
Overview
Organization of the nervous system
Autonomic outflow system
Organization of the ANS
Sympathetic division
Parasympathetic division
Functions of acetylcholine and norepinephrine
Cholinergic receptors
Autonomic plexuses
Hypothalamic control of ANS function
Chapter 19. Adrenergic agonists
Overview
Adrenergic agonists
Classifications of adrenergic agonists
Clinical case studies
Chapter 20. Adrenergic antagonists
Overview
Common adrenergic antagonists
Alpha-adrenergic antagonists
Beta-adrenergic antagonists
Nonselective beta-adrenergic antagonists
Selective beta1-adrenergic antagonists
Clinical case studies
Chapter 21. Cholinergic agonists
Overview
Cholinergic agonists
Classifications of cholinergic agonists
Clinical case studies
Chapter 22. Cholinergic antagonists
Overview
Cholinergic antagonists
Classifications of cholinergic antagonists
Clinical case studies
Unit IV. Pharmacology of psychiatric disorders
Chapter 23. Pharmacology of anxiety and sleep disorders
Overview
Anxiety disorders
Identification of brain areas involved in anxiety
Sleep disorders
Pharmacotherapy of anxiety and sleep disorders
Clinical case studies
Chapter 24. Pharmacology of depressive disorders
Overview
Major depressive disorder
Psychotherapy
Pharmacotherapy
Clinical case studies
Chapter 25. Pharmacology of bipolar disorder
Overview
Bipolar disorder
Pharmacotherapy
Clinical case studies
Chapter 26. Pharmacology of schizophrenia
Overview
Phases of schizophrenia
Psychotherapy
Pharmacotherapy
Clinical case studies
Chapter 27. Pharmacology for attention-deficit/hyperactivity disorder
Overview
Attention-deficit hyperactivity disorder
Behavioral therapy
Pharmacotherapy
Clinical case studies
Chapter 28. Pharmacology of dissociative disorders
Overview
Depersonalization/derealization disorder
Dissociative amnesia
Clinical case studies
Chapter 29. Pharmacology of personality disorders
Overview
Personality disorders
Pathophysiology
Diagnosis
Psychotherapy and pharmacotherapy
Clinical case studies
Chapter 30. Pharmacology of somatic symptom disorders
Overview
Somatic symptom disorders
Pathophysiology
Diagnosis
Psychotherapy and pharmacotherapy
Clinical case studies
Appendix A: list of high-alert medications
Appendix B: Toxicology effects on the nervous system
Appendix C: Answer key to clinical case studies
Glossary
Index

Jahangir Moini

Dr. Moini is an international author of 38 medical textbooks for various publishers including Elsevier, McGraw-Hill, Pearson, Jones & Bartlett Learning, Cengage Learning, and Routledge. In addition to continuing his venture as an author, he has been a professor for over 40 years. He is a retired professor with the Eastern Florida State College Science & Health Department. Previously, Dr. Moini was an assistant professor at Tehran University Medical School, Department of Epidemiology and Preventive Medicine. For 18 years, he was the Director of Epidemiology for the Brevard County Health Department. He was also Director of Allied Health at Everest University for 15 years.

Affiliations and expertise

Retired Professor, Science and Health Department, Eastern Florida State College, FL, USA

Anthony LoGalbo

Dr. LoGalbo is a Board Certified Clinical Neuropsychologist and Associate Professor in the School of Psychology at Florida Tech in Melbourne, Florida, where he teaches graduate coursework and conducts applied research in the clinical psychology (PsyD) program. He is also the clinical director and primary supervisor of Florida Tech's Sports Concussion Management Program, and the clinical neuropsychology director at the Health First Florida Memory Disorder Clinic. Previously, he was in clinical practice at Florida Hospital (AdventHealth) in Orlando, serving both inpatients and outpatients through the Neuroscience Institute and Department of Sports Medicine and Rehabilitation. Educationally, he earned a PhD in medical/clinical psychology with a focus on neuropsychology at the University of Alabama at Birmingham

Affiliations and expertise

Associate Professor, Florida Institute of Technology, School of Psychology, FL, USA

Jennifer G. Schnellmann

Dr. Schnellmann is an Associate Professor in the Department of Pharmacology, College of Pharmacy, at the University of Arizona. She is also Associate Director of Undergraduate Studies in Pharmaceutical Sciences. She is the author of seven books, on topics including cardiovascular pharmacology and strategies for gaining admission to professional school. She teaches medical, graduate, and undergraduate students across several courses in toxicology and pharmacology.

Affiliations and expertise

Associate Professor, Department of Pharmacology, College of Pharmacy, University of Arizona, Arizona, USA

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Neuropsychopharmacology

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Jahangir Moini

Anthony LoGalbo

Jennifer G. Schnellmann