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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Functional Neural Transplantation IV

    Translation to Clinical Application, Part A
    • 1st Edition
    • Volume 230
    • English
    Functional Neural Transplantation IV: Translation to Clinical Application, Volume 230 provides the current status of cell transplantation in the nervous system, with a focus on the conditions for achieving structural repair and functional recovery after brain damage or in neurodegenerative disease. New to this release are chapters that delve into the Mechanisms and Use of Neural Transplants for Brain Repair, Reprogramming of Somatic Cells: iPS and iN Cells, Brain Repair from Intrinsic Cell Sources: Turning Reactive Glia into Neurons, and Ex Vivo Gene Therapy for the Treatment of Neurological Disorders, Preparation, Characterization and Banking of Clinical-grade Cells for Neural Transplantation. As the fourth in a periodic series of updates at 5-7 year intervals, this volume highlights recent developments related to the application of advances in cellular and molecular science, providing an understanding of the fundamental principles of neuroplasticity and regeneration in the brain and spinal cord, and also addressing the topic of the power of pluripotent stem cells to generate new sources of precisely specified neurons for utilization in brain repair.

  • Neurochemical Aspects of Alzheimer's Disease

    Risk Factors, Pathogenesis, Biomarkers, and Potential Treatment Strategies
    • 1st Edition
    • Akhlaq A. Farooqui
    • English
    Neurochemical Aspects of Alzheimer's Disease provides a comprehensive overview of molecular aspects of risk factors, pathogenesis, biomarkers, and therapeutic strategies. The book focuses on molecular mechanisms and signal transduction processes associated with the pathogenesis, biomarkers, and therapeutic strategies of AD. The comprehensive and cutting edge information in this monograph may not only help in early detection of AD, but also promote discovery of new drugs to treat this chronic disease. Chapters discuss involvement of neural membrane phospholipids, sphingolipids, and cholesterol-derived lipid mediators, abnormal APP processing, and nucleic acid damage, risk factors, biomarker, and therapeutic strategies of Alzheimer's disease. This book is written for neurologists, neuroscientists, neurochemists, neuropharmacologists... and clinicianswho are interested in molecular mechanisms associated with the pathogenesis of age-related neurological disorders.

  • Designing EEG Experiments for Studying the Brain

    Design Code and Example Datasets
    • 1st Edition
    • Aamir Saeed Malik + 1 more
    • English
    Designing EEG Experiments for Studying the Brain: Design Code and Example Datasets details the design of various brain experiments using electroencephalogram (EEG). Providing guidelines for designing an EEG experiment, it is primarily for researchers who want to venture into this field by designing their own experiments as well as those who are excited about neuroscience and want to explore various applications related to the brain. The first chapter describes how to design an EEG experiment and details the various parameters that should be considered for success, while remaining chapters provide experiment design for a number of neurological applications, both clinical and behavioral. As each chapter is accompanied with experiment design codes and example datasets, those interested can quickly design their own experiments or use the current design for their own purposes. Helpful appendices provide various forms for one’s experiment including recruitment forms, feedback forms, ethics forms, and recommendations for related hardware equipment and software for data acquisition, processing, and analysis.

  • Arteriovenous and Cavernous Malformations

    • 1st Edition
    • Volume 143
    • English
    Arteriovenous and Cavernous Malformations, Volume 143, is the latest addition in the ongoing HCN series, an evidence-based compendium which addresses both the scientific and clinical aspects of this unique disease process. The volume covers didactic aspects, such as the epidemiology, etiology, and diagnosis of AVMs, while also providing expert clinical information on the management and treatment of these lesions. In addition, it provides coverage of modern-day advances in the genetics of cavernous malformations, as well as discussion regarding future open research questions. Readers from the laboratory bench to the bedside can expect a broad, yet objective, review of this pathology, with updates from the latest scientific literature and data supporting current practices.

  • Neuroscience Basics

    A Guide to the Brain's Involvement in Everyday Activities
    • 1st Edition
    • Jennifer L. Larimore
    • English
    Neuroscience Basics: A Guide to the Brain’s Involvement in Everyday Activities examines how our brain works in everyday activities like sleeping, eating, love, and exercise. Many want to better understand how the brain works, but the terminology and jargon of books can be overwhelming. The book covers the basics taught in an introductory neurobiology course designed for anyone new to the neuroscience field, including non-neuroscientists. While each of the chapters explore the brain in a normal state, Neuroscience Basics also discusses disruptions of the normal state—psychosis, Alzheimer’s, Parkinson’s, autism, learning disorders, etc. This book breaks down the topics into language that is more accessible while making the neuroscience topics fun and relevant.

  • The Neuroscience of Cocaine

    Mechanisms and Treatment
    • 1st Edition
    • Victor R. Preedy
    • English
    The Neuroscience of Cocaine: Mechanisms and Treatment explores the complex effects of this drug, addressing the neurobiology behind cocaine use and the psychosocial and behavioral factors that impact cocaine use and abuse. This book provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms. Cocaine is one of the most highly abused illicit drugs worldwide and is frequently associated with other forms of drug addiction and misuse, but researchers are still struggling to understand cocaine’s neuropharmacological profile and the mechanisms of its effects and manifestations at the cognitive level. Cessation of cocaine use can lead to numerous adverse withdrawal conditions, from the cellular and molecular level to the behavioral level of the individual user. Written by worldwide experts in cocaine addiction, this book assists neuroscientists and other addiction researchers in unraveling the many complex facets of cocaine use and abuse.

  • The Endocannabinoid System

    Genetics, Biochemistry, Brain Disorders, and Therapy
    • 1st Edition
    • Eric Murillo-Rodriguez
    • English
    The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy examines the cellular, biochemical, genetic, and therapeutic aspects of the endocannabinoid system. The chapters cover significant conceptual advances in the endocannabinoid field and shed light on the many brain disorders in which this biological system is involved. Written by world-leading experts in the field, the topics covered in this book will have a positive impact on the area of molecular biology, including, but not limited to, cell biology, neuroscience, pharmacology, signaling, disease mechanisms, and therapeutics.

  • Blanco's Overview of Alpha-1 Antitrypsin Deficiency

    History, Biology, Pathophysiology, Related Diseases, Diagnosis and Treatment
    • 1st Edition
    • Ignacio Blanco
    • English
    Blanco’s Overview of Alpha-1 Antitrypsin Deficiency: History, Biology, Pathophysiology, Related Diseases, Diagnosis, and Treatment is a robust introduction to topics associated with Alpha-1 Antitrypsin Deficiency (AATD). Included are topics ranging from the history of the disease, biology, pathophysiology, related diseases, including the two major manifestations of the disease (liver disease and lung disease), and diagnosis and treatment. The book addresses the need for the amalgamation of current and novel concepts and practices in the field of AATD. AATD is under-recognized in the medical community and, as a result, it is underdiagnosed. The book provides increased awareness and understanding of the condition to improve diagnosis rates and enhance patient care. This book is an essential tool and reference, beneficial to clinicians who screen and treat AATD patients, as well as research scientists working in the AATD field at junior and senior levels.

  • Biometals in Neurodegenerative Diseases

    Mechanisms and Therapeutics
    • 1st Edition
    • Anthony R. White + 3 more
    • English
    Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics is an authoritative and timely resource bringing together the major findings in the field for ease of access to those working in the field or with an interest in metals and their role in brain function, disease, and as therapeutic targets. Chapters cover metals in Alzheimer’s Disease, Parkinson’s Disease, Motor Neuron Disease, Autism and lysosomal storage disorders. This book is written for academic researchers, clinicians and advanced graduate students studying or treating patients in neurodegeneration, neurochemistry, neurology and neurotoxicology. The scientific literature in this field is advancing rapidly, with approximately 300 publications per year adding to our knowledge of how biometals contribute to neurodegenerative diseases. Despite this rapid increase in our understanding of biometals in brain disease, the fields of biomedicine and neuroscience have often overlooked this information. The need to bring the research on biometals in neurodegeneration to the forefront of biomedical research is essential in order to understand neurodegenerative disease processes and develop effective therapeutics.

  • A Roadmap for Curing Cancer, Alzheimer's, and Cardiovascular Disease

    • 1st Edition
    • Paul J. Marangos
    • English
    Cancer, dementia, and cardiovascular disease are responsible for almost two million deaths each year in the United States alone and represent the largest immediate threat to humanity. Over the last century, we have made spectacular advances that have transformed our society – splitting the atom, space travel, telecommunications, and the Internet – but with medical research focused mostly on science for the sake of science, it has yielded precious few cures. A Roadmap for Curing Cancer, Alzheimer’s, and Cardiovascular Disease represents a "first of its kind" effort to address both the reasons for this and to posit solutions to fix our broken system, in an effort to finally end this cure crisis. Dr. Marangos draws on 45 years of experience in every aspect of the biomedical R&D field, from basic drug discovery research at the NIH to the co-founding of five drug companies. He has published 252 research papers and edited four books on drug discovery, is co-inventor on 14 patents, and founded "The Journal of Molecular Neuroscience". He argues that from a development perspective, the regulatory, patent, and legal hurdles that force industry to pursue so-called "me-too" drugs rather than cures for terminal diseases must be re-thought. Leadership accountability, strategy, focus, and urgency need to be re-evaluated, and major reforms to the NIH, FDA, and patent codes are proposed.to remedy these impediments to cures. Written for anyone frustrated with the seemingly endless threat of terminal disease, this book seeks to inform, energize, and provide the rationale for the public and industry stakeholders, as well as clinicians and researchers, to resurrect the physician-patient relationship and demand that we get serious about ridding society of this scourge on humanity. This work contains the views and opinions of the author and are in no way intended to harm the reputation of any person, agency, organization, or commercial entity discussed herein. www.cureterminaldise...

  • Brain-Based Learning and Education

    Principles and Practice
    • 1st Edition
    • Yi-Yuan Tang
    • English
    Brain-Based Learning and Education presents a new type of education that uses brain-based and self-control theory-driven training. Leaving aside the current focus in education on content knowledge, it examines essential character strengths such as selfcontrol, persistence, creativity, attention, memory, and social learning, and relates their relevance to learning. By bridging the research and application gap in education, this text not only covers the latest findings related to learning and teaching but also provides insights for application and practice for brain-based methods in health and education. This integration of neuroscience and education takes us from a deep understanding of brain function to the frontline of the classroom.

  • Dementia, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 35-2
    • John M. Ringman
    • English
    This issue of Neurologic Clinics, edited by Dr. John Ringman, will cover a wider variety of topics and the latest updated on Demantia. Topics covered in this issue include, but are not limited to Updates on the basic science of AD; The role of neuropsychology in the assessment of the cognitively impaired elderly; Assessment of the Spanish-speaking cognitively impaired elderly; Early-Onset Alzheimer’s disease; Vascular dementia and vascular contributions to Alzheimer’s disease; Frontotemporal Degenerations; and Current and Experimental Treatments, among others.

  • Wilson Disease

    • 1st Edition
    • Volume 142
    • Anna Czlonkowska + 1 more
    • English
    Wilson Disease provides a comprehensive guide on this inherited genetic disorder that has devastating consequences for both the liver and neurologic/psychiatr... health. This disease is of increasing interest to neurologists, hepatologists, and geneticists, but when the disease is diagnosed early, it is treatable, with patients living normal lives. This volume describes the molecular pathophysiology of WD and the clinical and pathological effects of copper. Separate sections address both diagnosis and medical and surgical approaches to treatment. Both adult and pediatric perspectives on diagnosis and treatment are addressed, and a section on genetics highlights advances in molecular diagnostics. Patient support groups that can aid in coping with this disease are also discussed, as are animal models for those interested in basic research on cell biology, pathophysiology, and treatment.

  • Machine Dreaming and Consciousness

    • 1st Edition
    • J. F. Pagel + 1 more
    • English
    Machine Dreaming and Consciousness is the first book to discuss the questions raised by the advent of machine dreaming. Artificial intelligence (AI) systems meeting criteria of primary and self-reflexive consciousness are often utilized to extend the human interface, creating waking experiences that resemble the human dream. Surprisingly, AI systems also easily meet all human-based operational criteria for dreaming. These “dreams” are far different from anthropomorphic dreaming, including such processes as fuzzy logic, liquid illogic, and integration instability, all processes that may be necessary in both biologic and artificial systems to extend creative capacity. Today, multi-linear AI systems are being built to resemble the structural framework of the human central nervous system. The creation of the biologic framework of dreaming (emotions, associative memories, and visual imagery) is well within our technical capacity. AI dreams potentially portend the further development of consciousness in these systems. This focus on AI dreaming raises even larger questions. In many ways, dreaming defines our humanity. What is humanly special about the states of dreaming? And what are we losing when we limit our focus to its technical and biologic structure, and extend the capacity for dreaming into our artificial creations? Machine Dreaming and Consciousness provides thorough discussion of these issues for neuroscientists and other researchers investigating consciousness and cognition.

  • Advances in Imaging of Multiple Sclerosis, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 27-2
    • Alex Rovira
    • English
    This issue of Neuroimaging Clinics of North America focuses on Imaging of Multiple Sclerosis: Diagnosis and Management, and is edited by Dr. Àlex Rovira Cañellas. Articles will include: Multiple Sclerosis: Epidemiological, Clinical and Therapeutic Aspects; Brain and Spinal Cord MR Imaging Features in Multiple Sclerosis and Variants; Neuromyelitis Optica Spectrum Disorders; Radiologically Isolated Syndrome; MRI in Monitoring and Predicting Treatment Response in Multiple Sclerosis; Cortical Grey Matter MR Imaging in Multiple Sclerosis; Brain Atrophy in Multiple Sclerosis: Technical Aspects and Clinical Relevance; Iron Mapping in Multiple Sclerosis; Microstructural MR Techniques in Multiple Sclerosis; Molecular and Metabolic Imaging in Multiple Sclerosis; Insights from Ultra-high Field Imaging in Multiple Sclerosis; Pediatric Multiple Sclerosis: Distinguishing Clinical and MRI Features, and more!

  • Network Functions and Plasticity

    Perspectives from Studying Neuronal Electrical Coupling in Microcircuits
    • 1st Edition
    • Jian Jing
    • English
    Network Functions and Plasticity: Perspectives from Studying Neuronal Electrical Coupling in Microcircuits focuses on the specific roles of electrical coupling in tractable, well-defined circuits, highlighting current research that offers novel insights for electrical coupling‘s roles in sensory and motor functions, neural computations, decision-making, regulation of network activity, circuit development, and learning and memory. Bringing together a diverse group of international experts and their contributions using a variety of approaches to study different invertebrate and vertebrate model systems with a focus on the role of electrical coupling/gap junctions in microcircuits, this book presents a timely contribution for students and researchers alike.

  • Systems Factorial Technology

    A Theory Driven Methodology for the Identification of Perceptual and Cognitive Mechanisms
    • 1st Edition
    • Daniel Little + 3 more
    • English
    Systems Factorial Technology: A Theory Driven Methodology for the Identification of Perceptual and Cognitive Mechanisms explores the theoretical and methodological tools used to investigate fundamental questions central to basic psychological and perceptual processes. Such processes include detection, identification, classification, recognition, and decision-making. This book collects the tools that allow researchers to deal with the pervasive model mimicry problems which exist in standard experimental and theoretical paradigms and includes novel applications to not only basic psychological questions, but also clinical diagnosis and links to neuroscience. Researchers can use this book to begin using the methodology behind SFT and to get an overview of current uses and future directions. The collected developments and applications of SFT allow us to peer inside the human mind and provide strong constraints on psychological theory.

  • Disease-Modifying Targets in Neurodegenerative Disorders

    Paving the Way for Disease-Modifying Therapies
    • 1st Edition
    • Veerle Baekelandt + 1 more
    • English
    Disease-Modifying Targets in Neurodegenerative Disorders: Paving the Way for Disease-Modifying Therapies examines specific neurodegenerative disorders in comprehensive chapters written by experts in the respective fields. Each chapter contains a summary of the disease management field, subsequently elaborating on the molecular mechanisms and promising new targets for disease-modifying therapies. This overview is ideal for neuroscientists, biomedical researchers, medical doctors, and caregivers, not only providing readers with a summary of the way patients are treated today, but also offering a glance at the future of neurodegenerative disorder treatment.

  • Practical Stress Management

    A Comprehensive Workbook
    • 7th Edition
    • John A. Romas + 1 more
    • English
    Practical Stress Management: A Comprehensive Workbook, Seventh Edition, is a focused, personal, worksheet-based text that combines theory and principles with hands-on exercises to help readers manage the negative impact of stress in life. As a practical tool for recognizing and preventing stress, the action-oriented approach enables the student to make personal change through self-reflection and behavior change techniques. This approach allows the book to be used as a text in a course or as a self-study/reference book. In this edition, the authors cover financial stress and expand their section on sleep. The book is accompanied by online MP3 files of guided relaxation techniques and downloadable worksheets. In addition, worksheets and thoughts for reflection boxes help users determine their own level of stress and apply effective stress management techniques.

  • Essentials of Neuroanesthesia

    • 1st Edition
    • Hemanshu Prabhakar
    • English
    Essentials of Neuroanesthesia offers useful insights on the anesthetic management of neurosurgical and neurologic patients. This book covers all topics related to neuroanesthesia, providing essential knowledge on the brain and spinal cord. Sections include chapters on anatomy, physiology, and pharmacology, along with specific chapters related to various neurosurgical and neurological problems and their anesthetic management. This book provides an understanding of related issues, such as palliative care, evidence based practice of neuroanesthesia, sterilization techniques, biostatistics, and ethical issues, and is useful for trainees, clinicians, and researchers in the fields of neurosurgery, neurocritical care, neuroanesthesia, and neurology.

  • Adenosine Receptors in Neurodegenerative Diseases

    • 1st Edition
    • David Blum + 1 more
    • English
    Adenosine Receptors in Neurodegenerative Diseases covers the role of adenosine receptors in brain function, also focusing on related methodologies and perspectives in therapeutics. The book provides an up-to-date overview by the best specialists in the field, helping readers consider the importance of adenosine and expand the global impact and visibility of adenosine research in the CNS field. Chapters include adenosine biology and signaling, gene regulation, control of motor function, and novel adenosine-based therapies in the CNS. It is an ideal resource for researchers, advanced graduate students, clinicians, and industry scientists working in the fields of clinical neuroscience and molecular and cellular neuroscience.

  • Music, Passion, and Cognitive Function

    • 1st Edition
    • Leonid Perlovsky
    • English
    Music, Passion, and Cognitive Function examines contemporary cognitive theories of music, why they cannot explain music’s power over us, and the origin and evolution of music. The book presents experimental confirmations of the theory in psychological and neuroimaging research, discussing the parallel evolution of consciousness, musical styles, and cultures since Homer and King David. In addition, it explains that 'in much wisdom is much grief' due to cognitive dissonances created by language that splits the inner world. Music enables us to survive in this sea of grief, overcomes discomforts and stresses of acquiring new knowledge, and unifies the soul, hence the power of music.

  • Neural Data Science

    A Primer with MATLAB® and Python™
    • 1st Edition
    • Erik Lee Nylen + 1 more
    • English
    A Primer with MATLAB® and Python™ present important information on the emergence of the use of Python, a more general purpose option to MATLAB, the preferred computation language for scientific computing and analysis in neuroscience. This book addresses the snake in the room by providing a beginner’s introduction to the principles of computation and data analysis in neuroscience, using both Python and MATLAB, giving readers the ability to transcend platform tribalism and enable coding versatility.

  • Hearing Loss

    Causes, Prevention, and Treatment
    • 1st Edition
    • Jos J. Eggermont
    • English
    Hearing Loss: Causes, Prevention, and Treatment covers hearing loss, causes and prevention, treatments, and future directions in the field, also looking at the cognitive problems that can develop. To avoid the “silent epidemic” of hearing loss, it is necessary to promote early screening, use hearing protection, and change public attitudes toward noise. Successful treatments of hearing loss deal with restoring hearing sensitivity via hearing aids, including cochlear, brainstem, or midbrain implants. Both the technical aspects and effects on the quality of life of these devices are discussed. The integration of all aspects of hearing, hearing loss, prevention, and treatment make this a perfect one-volume course in audiology at the graduate student level. However, it is also a great reference for established audiologists, ear surgeons, neurologists, and pediatric and geriatric professionals.

  • Addictive Substances and Neurological Disease

    Alcohol, Tobacco, Caffeine, and Drugs of Abuse in Everyday Lifestyles
    • 1st Edition
    • Ronald Ross Watson + 1 more
    • English
    Addictive Substances and Neurological Disease: Alcohol, Tobacco, Caffeine, and Drugs of Abuse in Everyday Lifestyles is a complete guide to the manifold effects of addictive substances on the brain, providing readers with the latest developing research on how these substances are implicated in neurological development and dysfunction. Cannabis, cocaine, and other illicit drugs can have substantial negative effects on the structure and functioning of the brain. However, other common habituating and addictive substances often used as part of an individual’s lifestyle, i.e., alcohol, tobacco, caffeine, painkillers can also compromise brain health and effect or accentuate neurological disease. This book provides broad coverage of the effects of addictive substances on the brain, beginning with an overview of how the substances lead to dysfunction before examining each substance in depth. It discusses the pathology of addiction, the structural damage resulting from abuse of various substances, and covers the neurobiological, neurodegenerative, behavioral, and cognitive implications of use across the lifespan, from prenatal exposure, to adolescence and old age. This book aids researchers seeking an understanding of the neurological changes that these substances induce, and is also extremely useful for those seeking potential treatments and therapies for individuals suffering from chronic abuse of these substances.

  • Stress and Epigenetics in Suicide

    • 1st Edition
    • Vsevolod Rozanov
    • English
    Stress and Epigenetics in Suicidediscusses the central role of epigenetic modifications in suicidal behavior. As early-life stress and an individual's ability to cope with such stressors, combined with psychological factors, social factors, and existential and cognitive factors can predispose young people to suicidal behavior and put them at added risk of suicidal behavior later in life, this book provides readers with an overview of the neurobiology of stress, an introduction to the epigenetic changes induced by stress, and an understanding of how vulnerability and resilience to stress are built. It integrates these mechanisms into a biobehavioral model of suicide based on epigenetic marks, gene-environment interactions, and other stressors. More importantly, it provides future direction for research and discusses potential interventions. This book is an ideal and trusted resource for researchers and clinicians who are interested in learning how the environment can affect behavior through genetics, and for those seeking the development of new methods for suicide prevention.

  • Primer on Cerebrovascular Diseases

    • 2nd Edition
    • Louis R. Caplan + 6 more
    • English
    Primer on Cerebrovascular Diseases, Second Edition, is a handy reference source for scientists, students, and physicians needing reliable, up-to-date information on basic mechanisms, physiology, pathophysiology, and medical issues related to brain vasculature. The book consists of short, specific chapters written by international experts on cerebral vasculature, presenting the information in a comprehensive and easily accessible manner. Numerous changes have occurred in the field since the publication of the first edition in 1997, particularly our understanding of the genetic aspects of cerebrovascular disease. This updated edition reflects the advances made over the last two decades, not only demonstrating the promise for therapy, but also for a molecular understanding of cerebrovascular diseases. The new edition includes new and expanded topics, including carotid stenting, Iatrogenic causes of stroke, axonal transport and injury, RNAIs, proteomics, and more. 2018 BMA Medical Book Awards Highly Commended in Neurology.

  • The Human Sciences after the Decade of the Brain

    • 1st Edition
    • Jon Leefmann + 1 more
    • English
    The Human Sciences after the Decade of the Brain brings together exciting new works that address today’s key challenges for a mutual interaction between cognitive neuroscience and the social sciences and humanities. Taking up the methodological and conceptual problems of choosing a neuroscience approach to disciplines such as philosophy, history, ethics and education, the book deepens discussions on a range of epistemological, historical, and sociological questions about the "neuro-turn" in the new millennium. The book’s three sections focus on (i) epistemological questions posed by neurobiologically informed approaches to philosophy and history, (ii) neuroscience’s influence on explanations for social and moral behavior, and (iii) the consequences of the neuro-turn in diverse sectors of social life such as science, education, film, and human self-understanding. This book is an important resource both for students and scholars of cognitive neuroscience and biological psychology interested in the philosophical, ethical, and societal influences of—and on—their work as well as for students and scholars from the social sciences and humanities interested in neuroscience.

  • Translational Immunotherapy of Brain Tumors

    • 1st Edition
    • John H. Sampson
    • English
    Translational Immunotherapy of Brain Tumors gives researchers and practitioners an up-to-date and comprehensive overview of the field. Chapters include adoptive immunotherapy, immunosuppression, CAR therapy of brain tumors, and dendritic cell therapy for brain tumors. Very few agents have been shown to be efficacious in the treatment of malignant gliomas. Recently, there have been a number of studies demonstrating the potential success of immunotherapy for brain tumors. Immunotherapeutics are becoming the most frequent drugs to be used in cancer therapy. These new breakthroughs, now approved by the FDA, are a part of multiple phase III international trials and ongoing research in malignant glioma, meaning that the information in this cutting-edge book will be of great importance to practitioners and researchers alike. 2018 BMA Medical Book Awards Highly Commended in Oncology

  • Mathematics for Neuroscientists

    • 2nd Edition
    • Fabrizio Gabbiani + 1 more
    • English
    Mathematics for Neuroscientists, Second Edition, presents a comprehensive introduction to mathematical and computational methods used in neuroscience to describe and model neural components of the brain from ion channels to single neurons, neural networks and their relation to behavior. The book contains more than 200 figures generated using Matlab code available to the student and scholar. Mathematical concepts are introduced hand in hand with neuroscience, emphasizing the connection between experimental results and theory.

  • Critical Care Neurology Part I

    Neurocritical Care
    • 1st Edition
    • Volume 140
    • English
    Critical Care Neurology, Part I: Neurocritical Care focuses on the care specialists and general neurologists that consult in the ICU and their work with patients in acute, life-threatening situations who are dealing with neurologic or neurosurgical crises emanating from either a preexisting neurologic syndrome or from a new neurologic complication appearing as a result of another medical or surgical critical illness. These two separate clinical situations form the pillars of neurocritical care, hence these practices are addressed via two separate, but closely related, HCN volumes. Chapters in both focus on pathophysiology and management, and are tailored for both general neurologists and active neurocritical specialists, with a specific focus on management over diagnostics. Part I addresses the principles of neurocritical care and the management of various neurologic diseases. Part II addresses the interplay between neurologic complications and the surgical, medical, cardiac, and trauma of critical illnesses that most typically present in the ICU.

  • Critical Care Neurology Part II

    Neurology of Critical Illness
    • 1st Edition
    • Volume 141
    • English
    Critical Care Neurology, Part II: Neurology of Critical Illness focuses on the care specialists and general neurologists that consult in the ICU and their work with patients in acute, life-threatening situations who are dealing with neurologic or neurosurgical crises emanating from either a preexisting neurologic syndrome or from a new neurologic complication appearing as a result of another medical or surgical critical illness. These two separate clinical situations form the pillars of neurocritical care, hence these practices are addressed via two separate, but closely related, HCN volumes. Chapters in both focus on pathophysiology and management, and are tailored for both general neurologists and active neurocritical specialists, with a specific focus on management over diagnostics. Part I addresses the principles of neurocritical care and the management of various neurologic diseases. Part II addresses the interplay between neurologic complications and the surgical, medical, cardiac, and trauma of critical illnesses that most typically present in the ICU.

  • Sleep and Neurologic Disease

    • 1st Edition
    • Mitchell G. Miglis
    • English
    Sleep and Neurologic Disease reviews how common neurologic illnesses, such as Parkinson’s Disease and Alzheimer’s dementia impact sleep. In addition, the book discusses how common primary sleep disorders influence neurologic diseases, such as the relationship between obstructive sleep apnea and stroke, as well as their association with various primary headache disorders and epilepsy syndromes. The utilization of sleep technology, such as polysomnography, multiple sleep latency testing, actigraphy, laboratory and CSF testing is also covered. The book is written for the practicing neurologist, sleep physician, neuroscientist, and epidemiologist studying sleep.

  • Innovative Neuromodulation

    • 1st Edition
    • Jeffrey Arle + 1 more
    • English
    Innovative Neuromodulation serves as an extensive reference that includes a basic introduction to the relevant aspects of clinical neuromodulation that is followed by an in-depth discussion of the innovative surgical and therapeutic applications that currently exist or are in development. This information is critical for neurosurgeons, neurophysiologists, bioengineers, and other proceduralists, providing a clear presentation of the frontiers of this exciting and medically important area of physiology. As neuromodulation remains an exciting and rapidly advancing field—appealing to many disciplines—the editors’ initial work (Essential Neuromodulation, 2011) is well complemented by this companion volume.

  • Molecular and Cellular Therapies for Motor Neuron Diseases

    • 1st Edition
    • Nicholas M Boulis + 2 more
    • English
    Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians. Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig’s Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials.

  • Neurocritical Care Management of the Neurosurgical Patient

    • 1st Edition
    • Monisha Kumar + 3 more
    • English
    Kumar and colleagues’ Neurocritical Care Management of the Neurosurgical Patient provides the reader with thorough coverage of neuroanatomical structures, operative surgical approaches, anesthetic considerations, as well as the full range of known complications relating to elective and non-elective neurosurgical procedures. Drawing upon the expertise of an interdisciplinary team of physicians from neurosurgery, neurology, anesthesiology, critical care, and nursing backgrounds, the text covers all aspects intensivists need to be aware of in order to provide optimal patient care.

  • Handbook of Cannabis and Related Pathologies

    Biology, Pharmacology, Diagnosis, and Treatment
    • 1st Edition
    • Victor R. Preedy
    • English
    Handbook of Cannabis and Related Pathologies: Biology, Pharmacology, Diagnosis, and Treatment is the first book to take an interdisciplinary approach to the understanding of cannabis use and misuse. Recent worldwide trends toward decriminalizing marijuana for medical use have increased legal use of the drug and recreational use remains high, making cannabis one of the most commonly used drugs.Cannabis has a wide range of adverse neurological effects, and use and abuse can lead to physical, social, and psychopathological issues that are multifarious and complex. Effective understanding and treatment requires knowledge of the drug’s effects from across scientific disciplines.This book provides an overview of the biological and pharmacological components of the cannabis plant, outlines its neurological, social, and psychopathological effects, assists in the diagnosis and screening for use and dependency, and aids researchers in developing effective treatments for cannabis-related issues and disorders.Fully illustrated, with contributions from internationally recognized experts, it is the go-to resource for neuroscientists, pharmacologists, pathologists, public-health workers, and any other researcher who needs an in-depth and cross-disciplinary understanding of cannabis and its effects.

  • The Pituitary

    • 4th Edition
    • Shlomo Melmed
    • English
    The Pituitary, Fourth Edition, continues the tradition of a cogent blend of basic science and clinical medicine which has been the successful hallmark of prior editions. This comprehensive text is devoted to the pathogenesis, diagnosis, and treatment of pituitary disorders. The new edition has been extensively revised to reflect new knowledge derived from advances in molecular and cell biology, biochemistry, diagnostics, and therapeutics as they apply to the pituitary gland. The wide spectrum of clinical disorders emanating from dysfunction of the master gland is described in detail by experts in the field. Fundamental mechanisms underlying disease pathogenesis are presented to provide the reader with an in-depth understanding of mechanisms subserving both normal and disordered pituitary hormone secretion and action. This extensive body of knowledge is useful for students, trainees, physicians, and scientists who need to understand critical pituitary functions and how to care for patients with pituitary disorders. Chapters provide medical students, clinical and basic endocrinology trainees, endocrinologists, internists, pediatricians, gynecologists, and neurosurgeons with a comprehensive, yet integrated, text devoted to the science and art of pituitary medicine.

  • DNA Modifications in the Brain

    Neuroepigenetic Regulation of Gene Expression
    • 1st Edition
    • Timothy W Bredy
    • English
    DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and diseased states. Chapters describe new directions and technological advances, and provide an overview of what the future holds for this exciting new field. This book is ideal for medical, graduate and advanced undergraduate students, but is also a great resource for researchers who need a broad introduction to the dynamic nature of DNA that sheds light on evolving concepts of gene-environment interaction and their effects on adaptation and neuropsychiatric disease.

  • Nutrition and Lifestyle in Neurological Autoimmune Diseases

    Multiple Sclerosis
    • 1st Edition
    • Ronald Ross Watson + 1 more
    • English
    Nutrition and Lifestyle in Neurological Autoimmune Diseases: Multiple Sclerosis discusses important discoveries relating to the types of, and efficacy of, nutritional and lifestyle responses to symptoms and reoccurrence of MS. Each chapter defines a new approach to use in foods, dietary supplements, exercise, behavior, and/or lifestyle in health promotion and symptoms management for MS. This book presents the role of non-pharmaceutical approaches and is essential reading for neurologists, physicians, nurses, nutritionists, dietitians, healthcare professionals, research scientists, biochemists, and general practitioners.

  • Stress: Neuroendocrinology and Neurobiology

    Handbook of Stress Series, Volume 2
    • 1st Edition
    • George Fink
    • English
    Stress: Neuroendocrinology and Neurobiology: Handbook of Stress Series, Volume 2, focuses on neuroendocrinology, the discipline that deals with the way that the brain controls hormonal secretion, and in turn, the way that hormones control the brain. There have been significant advances in our understanding of neuroendocrine molecular and epigenetic mechanisms, especially in the way in which stress-induced hormonal and neurochemical changes affect brain plasticity, neuronal connectivity, and synaptic function. The book features the topic of epigenetics, and how it enables stress and other external factors to affect genetic transmission and expression without changes in DNA sequence. Integrated closely with new behavioral findings and relevance to human disorders, the concepts and data in this volume offer the reader cutting-edge information on the neuroendocrinology of stress. Volume 2 is of prime interest to neuroscientists, clinicians, researchers, academics, and graduate students in neuroendocrinology, neuroscience, biomedicine, endocrinology, psychology, psychiatry, and in some areas of the social sciences, including stress and its management in the workplace.

  • Pediatric Brain Tumors Update, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 27-1
    • Lara A. Brandão
    • English
    This issue of Neuroimaging Clinics of North America focuses on Pediatric Brain Tumors, and is edited by Dr. Lara A. Brandão. Articles will include: Posterior fossa tumors in pediatric patients; Supratentorial tumors in pediatric patients; Brain tumors in the neonate; Pineal region masses in pediatric patients; Sellar and suprasellar tumors in pediatric patients; Extraparenchymal lesions in pediatric patients; Tumor and tumor-like masses in pediatric patients that involve multiple spaces; Neuroimaging of innovative peptide base vaccine therapy in pediatric brain tumors; Advanced MRI in pediatric brain tumors: clinical applications; and much more!

  • Neuro-Ophthalmology, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 35-1
    • Andrew G. Lee
    • English
    This issue of Neurologic Clinics, edited by Dr. Andrew Lee, will focus on Neuro-Ophthalmology. The topics covered in the issue include, but are not limited to new treatments for nonarteritic anterior ischemic optic neuropathy; idiopathic intracranial hypertension; neuroimaging for the Horner Syndrome; OCT; erectile dysfunction agents and NAION; NMO; ocular myasthenia gravis; imaging for third nerve palsy; treatment of central retinal artery occlusion; and orbital disease, among others.

  • Evolution of Nervous Systems

    • 2nd Edition
    • Jon H. Kaas + 5 more
    • English
    Evolution of Nervous Systems, Second Edition, Four Volume Set is a unique, major reference which offers the gold standard for those interested both in evolution and nervous systems. All biology only makes sense when seen in the light of evolution, and this is especially true for the nervous system. All animals have nervous systems that mediate their behaviors, many of them species specific, yet these nervous systems all evolved from the simple nervous system of a common ancestor. To understand these nervous systems, we need to know how they vary and how this variation emerged in evolution. In the first edition of this important reference work, over 100 distinguished neuroscientists assembled the current state-of-the-art knowledge on how nervous systems have evolved throughout the animal kingdom. This second edition remains rich in detail and broad in scope, outlining the changes in brain and nervous system organization that occurred from the first invertebrates and vertebrates, to present day fishes, reptiles, birds, mammals, and especially primates, including humans. The book also includes wholly new content, fully updating the chapters in the previous edition and offering brand new content on current developments in the field. Each of the volumes has been carefully restructured to offer expanded coverage of non-mammalian taxa, mammals, primates, and the human nervous system. The basic principles of brain evolution are discussed, as are mechanisms of change. The reader can select from chapters on highly specific topics or those that provide an overview of current thinking and approaches, making this an indispensable work for students and researchers alike.

  • Principles of Animal Research for Graduate and Undergraduate Students

    • 1st Edition
    • Mark A. Suckow + 1 more
    • English
    Principles of Animal Research is the first publication to offer a broad look at animal research science for a student, early researcher, or technician. Offering guidance for all aspects of the research experience, including the research and development of a thesis, model selection, experimental design, IACUC protocol preparation, and animal husbandry and technical procedural needs, the book is a necessary addition to every student, technician, and researcher’s education.

  • Hormones, Brain and Behavior

    • 3rd Edition
    • Donald W. Pfaff + 1 more
    • English
    Hormones, Brain and Behavior, Third Edition offers a state-of-the-art overview of hormonally-mediated behaviors, including an extensive discussion of the effects of hormones on insects, fish, amphibians, birds, rodents, and humans. Entries have been carefully designed to provide a valuable source of information for students and researchers in neuroendocrinology and those working in related areas, such as biology, psychology, psychiatry, and neurology. This third edition has been substantially restructured to include both foundational information and recent developments in the field. Continuing the emphasis on interdisciplinary research and practical applications, the book includes articles aligned in five main subject sections, with new chapters included on genetic and genomic techniques and clinical investigations. This reference provides unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics. The topics cover an unusual breadth (from molecules to ecophysiology), ranging from basic science to clinical research, making this reference of interest to a broad range of scientists in a variety of fields.

  • Motivation

    Theory, Neurobiology and Applications
    • 1st Edition
    • Volume 229
    • English
    Motivation: Theory, Neurobiology and Applications is inspired by a question central to health care professionals, teachers, parents, and coaches alike, "How can an individual be motivated to perform a given activity or training?" It presents novel measurements of motivation developed in psychology and economics, recent insights into the neurobiology of motivation, and current research on applications designed to boost motivation in neurorehabilitation, education, and sports. In addition, tactics on how to connect these different research and knowledge fields within a common (theoretical) framework of motivation is discussed. Thus, in short, the book provides an integrative, interdisciplinary, up-to-date accounting on the neurobiology of motivation and how it might be boosted.

  • Gut Microbiome and Behavior

    • 1st Edition
    • Volume 131
    • English
    Gut Microbiome and Behavior, the latest volume in the International Review of Neurobiology series, provides a comprehensive overview of the gut microbiome on the brain and behavior, fully encapsulating the latest research in the field and defining the scope of this influence to outline potential mechanisms and possible implications.

  • Spinal Muscular Atrophy

    Disease Mechanisms and Therapy
    • 1st Edition
    • Charlotte J Sumner + 2 more
    • English
    Spinal Muscular Atrophy: Disease Mechanisms and Therapy provides the latest information on a condition that is characterized by motoneuron loss and muscle atrophy, and is the leading genetic cause of infant mortality. Since the identification of the gene responsible for SMA in 1995, there have been important advances in the basic understanding of disease mechanisms, and in therapeutic development. This book provides a comprehensive accounting of recent advances in basic and clinical research that covers SMA clinical features and standards of care, multifaceted aspects of SMN protein functions and SMA disease pathology, various animal models, and biomarkers, as well as current therapeutic development. This title is ideal for graduate students/postdocs and principal investigators who are already in the SMA field and need to keep updated on recent findings and approaches, and for those who are new to, or would like to join, the field. Likewise, users will find an excellent source of reading for biotech/pharma scientists, clinical researchers, and practitioners, regulators, and patients and their advocacy organizations. Furthermore, this book is a handy reference for researchers and clinicians who may want to apply the research strategies and therapeutic approaches in SMA to other rare diseases.

  • Cardioskeletal Myopathies in Children and Young Adults

    • 1st Edition
    • John Lynn Jefferies + 3 more
    • English
    Cardioskeletal Myopathies in Children and Young Adults focuses on plaques that kill people in their 40’s-50’s and the way they start to form in young adulthood. The Annals of Family Medicine report that approximately half of young adults have at least one cardiovascular disease risk factor (Mar 2010), and an increase in cardiovascular mortality rates in young adults was substantiated in a study at Northwestern Medicine (Nov 2011). Given the increasing recognition of genetic triggers behind all types of cardiovascular disease, and the growing population of young adults with primary or acquired myocardial disease, the need has arisen for a reference that offers a comprehensive approach to the understanding of basic, translational, and clinical aspects of specific muscle diseases while making the link between young adult and adult health.

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