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Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Epilepsy, Infantile Spasms, and Developmental Encephalopathy

    • 1st Edition
    • Volume 49
    • May 23, 2002
    • English
    Epilepsy, Infantile Spasms, and Developmental Encephalopathy explores the nature and bases of infantile spasms - a major representative of the catastrophic developmental seizure disorders seen in early childhood. Although this topic has received considerable attention as a clinical disorder, the underlying pathogenesis of infantile spasms remains poorly understood. The aim is not simply to describe and label the clinical phenomenology associated with infantile spasms, but rather to work toward an understanding of the underlying mechanisms and of effective treatment strategies. The result is a volume with a high density of exciting ideas that can be taken to the bedside or to the laboratory for further study.Approaching the subject from an interdisciplinary perspective, this book integrates clinical and basic science in its discussion of infantile spasms as representative of a common developmental brain disorder. It also provides experimentally testable hypotheses to direct further research, and presents reviews of the literature associated with suggested underlying mechanisms.

  • Do Seizures Damage The Brain

    • 1st Edition
    • Volume 135
    • May 15, 2002
    • T. Sutula + 1 more
    • English
    What are the consequences, if any, of repeated brief seizures that are the defining feature of epilepsy? A firm answer to this question has been surprisingly elusive for a variety of reasons. Clearly there is a subset of patients who appear to tolerate seizures with relatively limited long-term consequences, and not all patients are destined to progress to intractability with frequent seizures and disability. This variability and individual susceptibility has made it difficult to make statements that fairly apply to the full range of people with epileptic disorders, whose disorders span a broad spectrum from mild with excellent control and few limitations, to severe with multiple daily seizures and pronounced disability that affects employment, educational performance, an personal life.This volume seeks to explore the spectrum of severe to more subtle damage that may be a consequence of seizures. The contributing authors have addressed these questions and related issues using a variety of methods in experimental models and in patients with epilepsy.

  • Changing Views of Cajal's Neuron

    • 1st Edition
    • Volume 136
    • May 14, 2002
    • E.C. Azmitia + 4 more
    • English
    Cajal is the Father of Neuroscience and his personal view of the Neuron has dominated the field for over 100 years. No single person has been able to challenge his global perspective of the neuron gained by Cajal's work in neuroanatomy, development, physiology, evolution and medicine. However, over 30 neuroscientists from around the world have accepted the challenge of writing a review article on "Changing Views of Cajal's Neuron". Many of these experts admitted they could only add to Cajal's theory and they carefully provided their new findings based on modern methods of microscopy, molecular biology or neurobiology. Other experts recognized specific areas where Cajal's ideas of neurons needed to be altered and refined. Key knowledge necessary to understand plasticity or development is now available and permits a changed view. A few of the authors directly challenged some of the most widely accepted and cherished theories of Cajal: the neuron as an isolated unit, function of dendrites, the direction of electrical conductivity and the importance of plasticity in the adult brain. In total, the collection of articles provides a fascinating perspective to the enormous force of Cajal's genius in the 21st Century view of the neuron.

  • Universes in Delicate Balance: Chemokines and the Nervous System

    • 1st Edition
    • April 29, 2002
    • R.M. Ransohoff + 4 more
    • English
    It is commonly acknowledged that the nervous system and the immune system, those most complex of networks, share attributes beyond their intricacy. Elements common to the two systems include memory, connectivity, flexibility and developmental selection of cellular composition by a rigorous process involving widespread programmed cell death. There is one salient difference: the cells of the immune system are predominantly in constant motion, while post-mitotic neurons and glia are largely fixed in place. Therefore, chemokines, initially characterized as leukocyte chemoattractants, have for the last one and one-half decades been intensely and productively studied in the contexts of inflammation, immunity and hematopoietic development.Only recently have the two fields, neurobiology and immunology, displayed mutual interests in chemokines. This convergence of the two tribes of investigators was catalyzed by the finding that SDF-1 (now known as CXCL12) and its receptor, CXCR4, exerted significant and similar functions in development of both nervous and immune systems. Indeed CXCL12 and CXCR4 were required, in an uncannily similar fashion, for retention of pre-B lymphocytes at sites of maturation in the bone marrow and of neuronal progenitors in the external granule cell layer of the developing cerebellum. Recent reports indicate that chemoattraction of cerebellar granule cells through CXCR4 can be suppressed by reverse signaling initiated by binding of soluble eph receptors to transmembrane ephrin B, thereby establishing a link between chemokine action and a cardinal patterning system of the developing nervous system. As may be anticipated when a dam breaks, a massive influx of correlative observations in the nervous and immune systems is likely to ensue.This volume represents the state of current knowledge. To this end, introductory material for both systems is provided. Basic and advanced 'chemokinology' are presented. The recipe for making a nervous system (both ingredients and instructions for preparation) is described, as are the roles of chemokines and their receptors in making an immune system. Given their importance and complexity, CXCL12/CXCR4 interactions are separately treated in varying contexts.The field of 'neurobiology of chemokines' has not lain fallow during the last ten years. During much of this time the principal focus has been on neuroinflammation. Linking the immune and nervous systems are explanations of the functions of chemokines and their receptors for resident brain macrophages, the microglia, the unique cerebrovascular endothelium and angiogenesis.Underst... human disease is the goal of much of this research. New discoveries are being made and reported at a gratifying rate. It is expected that this volume will promote the steady production and application of useful new knowledge in this developing field. It provides a unique single-source database for basic neurobiology highlighting the fundamental aspects of chemokines and discussing the relations of chemokine science to animal models and human disease.

  • Growth and Lactogenic Hormones

    • 1st Edition
    • Volume 2
    • April 18, 2002
    • L. Matera + 1 more
    • English
    For more than seventy years evidence has accumulated documenting the existence of a bi-directional communication network between growth hormone and the immune system. In the past twenty years there has been a tremendous proliferation of information detailing the workings of the growth hormone and insulin-like growth factor axis. A multitude of growth factors and binding proteins have been identified. More and more evidence supporting the important role of the growth hormone IGF network in the well functioning of the normal immune system has been documented. Clearly the challenge today is not to prove, but to understand, the neuroimmune regulatory role of GLH in its entire complexity.The ultimate goal of this volume and of all the other volumes of this series is to promote the understanding of the science and to ease human suffering.

  • Brain Lipids and Disorders in Biological Psychiatry

    • 1st Edition
    • Volume 35
    • February 21, 2002
    • E.R. Skinner
    • English
    Leading authorities examine the possible role of brain lipids in the development of conditions such as schizophrenia, depression, Alzheimer's disease and personality disorders and violence. A better understanding of the underlying causes of these debilitating medical disorders is of utmost importance and may contribute towards a means of prevention, amelioration and cure. The book is intended to stimulate further interest and lead to increased research in this important development area.

  • Handbook of Complementary and Alternative Therapies in Mental Health

    • 1st Edition
    • December 10, 2001
    • Scott Shannon
    • English
    Scott Shannon is an MD, president elect of the American Holistic Medical Association, and considered a national expert on holistic psychiatry. In this book he brings together a comprehensive overview of CAM treatments, with information on their effectiveness and safety for specific patient populations and for use in treating specific disorders. Modalities covered include Acupuncture, Nutritional Medicine, Herbal Medicine, Meditation, Biofeedback, Aromatherapy and others. Coverage also includes chapters on the best CAM modalities for treatment of Anxiety and PTSD, Depression, ADD, and Addictions. Each chapter will be in a similar template, beginning with a description of the treatment, its safety, compatibility with conventional treatments and/or contrindications, scientific documentation of its efficacy, discussion of which disorders it is best used for, and references.

  • Advances in the Study of Behavior

    • 1st Edition
    • Volume 31
    • December 3, 2001
    • English
    The aim of Advances in the Study of Behavior remains as it has been since the series began: to serve the increasing number of scientists who are engaged in the study of animal behavior by presenting their theoretical ideas and research to their colleagues and to those in neighboring fields. We hope that the series will continue its "contribution to the development of the field", as its intended role was phrased in the Preface to the first volume in 1965. Since that time, traditional areas of animal behavior have achieved new vigor by the links they have formed with related fields and by the closer relationship that now exists between those studying animal and human subjects.Advances in the Study of Behavior, Volume 31 continues to serve scientists across a wide spectrum of disciplines. Focusing on new theories and research developments with respect to behavioral ecology, evolutionary biology, and comparative psychology, these volumes foster cooperation and communications in these dense fields.

  • Vision: From Neurons to Cognition

    • 1st Edition
    • Volume 134
    • October 25, 2001
    • C. Casanova + 1 more
    • English
    Internationally renowned researchers discuss how the various parts of the brain process and integrate visual signals, providing up to date original findings, reviews, and theoretical proposals on visual processing.This book addresses the basic mechanisms of visual perception as well as issues such as neuronal plasticity, functional reorganization and recovery, residual vision, and sensory substitution. Knowledge of the basic mechanisms by which our brain can analyze, reconstruct, and interpret images in the external world is of fundamental importance for our capacity to understand the nature and causes of visual deficits, such as those resulting from ischemia, abnormal development, neuro-degenerative disorders, and normal aging. It is also essential to our goal of developing better therapeutic strategies, such as early diagnosis, visual training, behavioral rehabilitation of visual functions, and visual implants.

  • The Cat Primary Visual Cortex

    • 1st Edition
    • October 15, 2001
    • Bertram Payne + 1 more
    • English
    Written by experts on the forefront of investigations of brain function, vision, and perception, the material presented is of an unparalleled scientific quality, and shows that analyses of enormous breadth and sophistication are required to probe the structure and function of brain regions. The articles are highly persuasive in showing what can be achieved by carrying out careful and imaginative experiments. The Cat Primary Visual Cortex should emerge as essential reading for all those interested in cerebral cortical processing of visual signals or researching or working in any field of vision.

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