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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • New Targeting in The Reversal of Resistant Glioblastomas

      • 1st Edition
      • Volume 14
      • March 5, 2021
      • Ali Syed Arbab
      • English
      • Hardback
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      • eBook
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      New Targeting in The Reversal of Resistant Glioblastomas discusses alternative treatment strategies that not only target tumor cells but also target the tumor microenvironment, metabolic pathways and interaction of cytokines in tumor cells. The current treatment for primary and recurrent glioblastomas is failing because clinicians are not considering the effect of bone marrow derived cells to the development of resistance to clinically practiced therapies. This book helps readers rethink treatment strategies to successfully fight glioblastomas. It is a valuable resource for cancer researchers, clinicians, graduate students and other members of the biomedical field.

    • Research and Clinical Applications of Targeting Gastric Neoplasms

      • 1st Edition
      • July 17, 2021
      • Brendan Jenkins
      • English
      • Paperback
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      • eBook
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      Research and Clinical Applications of Targeting Gastric Neoplasms provides a comprehensive overview of gastrointestinal cancers, covering preclinical research and clinical findings related to risk factors, current treatment regimens (including immunotherapy), screening/detection methods, etiology of disease, precision medicine and future perspectives. Gastrointestinal cancers rank among the most lethal and common worldwide, and as such, there is intense research into their diverse causes and treatment options. This reference provides a consolidation of the research, making it a perfect resource for basic science and clinical researchers as well as oncologists who work in gastroenterology and GI tract cancer fields.

    • Biological Macromolecules

      • 1st Edition
      • November 18, 2021
      • Amit Kumar Nayak + 2 more
      • English
      • Paperback
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      • eBook
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      Biological Macromolecules: Bioactivity and Biomedical Applications presents a comprehensive study of biomacromolecules and their potential use in various biomedical applications. Consisting of four sections, the book begins with an overview of the key sources, properties and functions of biomacromolecules, covering the foundational knowledge required for study on the topic. It then progresses to a discussion of the various bioactive components of biomacromolecules. Individual chapters explore a range of potential bioactivities, considering the use of biomacromolecules as nutraceuticals, antioxidants, antimicrobials, anticancer agents, and antidiabetics, among others. The third section of the book focuses on specific applications of biomacromolecules, ranging from drug delivery and wound management to tissue engineering and enzyme immobilization. This focus on the various practical uses of biological macromolecules provide an interdisciplinary assessment of their function in practice. The final section explores the key challenges and future perspectives on biological macromolecules in biomedicine.

    • New Paradigms in Computational Modeling and Its Applications

      • 1st Edition
      • January 9, 2021
      • Snehashish Chakraverty
      • English
      • Paperback
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      • eBook
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      In general, every problem of science and engineering is governed by mathematical models. There is often a need to model, solve and interpret the problems one encounters in the world of practical problems. Models of practical application problems usually need to be handled by efficient computational models. New Paradigms in Computational Modeling and Its Applications deals with recent developments in mathematical methods, including theoretical models as well as applied science and engineering. The book focuses on subjects that can benefit from mathematical methods with concepts of simulation, waves, dynamics, uncertainty, machine intelligence, and applied mathematics. The authors bring together leading-edge research on mathematics combining various fields of science and engineering. This perspective acknowledges the inherent characteristic of current research on mathematics operating in parallel over different subject fields. New Paradigms in Computational Modeling and Its Applications meets the present and future needs for the interaction between various science and technology/engineeri... areas on the one hand and different branches of mathematics on the other. As such, the book contains 13 chapters covering various aspects of computational modeling from theoretical to application problems. The first six chapters address various problems of structural and fluid dynamics. The next four chapters include solving problems where the governing parameters are uncertain regarding fuzzy, interval, and affine. The final three chapters will be devoted to the use of machine intelligence in artificial neural networks.

    • Recent Advances in iPSCs for Therapy

      • 1st Edition
      • January 30, 2021
      • Alexander Birbrair
      • English
      • Paperback
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      • eBook
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      The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Recent Advances in iPSCs for Therapy, Volume 3 addresses the use of induced pluripotent stem cells for therapy of several disorders. The volume teaches the reader about the biology of induced pluripotent stem cells and their possible use as cell therapy. Remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cell types, tissues and organs using state-of-art techniques. This volume will cover what we know so far about the use of iPSCs for therapy of multiple diseases, such as: hair loss disorders, Parkinson’s disease, Huntington’s disease, ischemic stroke, Alzheimer’s disease, Glaucoma, Optic Neuropathy, Age-Related Macular Degeneration, Type 1 Diabetes, Heart Failure, liver diseases, infertility, Autoimmune Diseases, and more. The volume is written for researchers and scientists interested in cell therapy, stem cell biology, regenerative medicine, and organ transplantation and is contributed by world-renowned authors in the field.

    • Epigenetics in Cardiovascular Disease

      • 1st Edition
      • Volume 24
      • March 6, 2021
      • Yvan Devaux + 1 more
      • English
      • Paperback
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      • eBook
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      Epigenetics in Cardiovascular Disease, a new volume in the Translational Epigenetics series, offers a comprehensive overview of the epigenetics mechanisms governing cardiovascular disease development, as well as instructions in research methods and guidance in pursing new studies. More than thirty international experts provide an (i) overview of the epigenetics mechanisms and their contribution to cardiovascular disease development, (i) high-throughput methods for RNA profiling including single-cell RNA-seq, (iii) the role of nucleic acid methylation in cardiovascular disease development, (iv) epigenetic actors as biomarkers and drug targets, (v) and the potential of epigenetics to advance personalized medicine. Here, readers will discover strategies to combat research challenges, improve quality of their epigenetic research and reproducibility of their findings. Additionally, discussion of assay and drug development for personalized healthcare pave the way for a new era of understanding in cardiovascular disease.

    • Biologically Active Peptides

      • 1st Edition
      • June 17, 2021
      • Fidel Toldra + 1 more
      • English
      • Paperback
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      • eBook
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      Biologically Active Peptides: From Basic Science to Applications for Human Health stands as a comprehensive resource on bioactive peptide science and applications. With contributions from more than thirty global experts, topics discussed include bioactive peptide science, structure-activity relationships, best practices for their study and production, and their applications. In the interdisciplinary field of bioactive peptides, this book bridges the gap between basic peptide chemistry and human physiology, while reviewing recent advances in peptide analysis and characterization. Methods and technology-driven chapters offer step-by-step guidance in peptide preparation from different source materials, bioactivity assays, analysis and identification of bioactive peptides, encoding bioactive peptides. Later, applications across disease areas and medical specialties are examined in-depth, including the use of bioactive peptides in treating obesity, diabetes, osteoporosis, mental health disorders, food allergies, and joint health, among other disorders, as well as bioactive peptides for sensory enhancement, sports and clinical nutrition, lowering cholesterol, improving cardiovascular health, and driving advances in biotechnology.

    • Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies

      • 1st Edition
      • Volume 15
      • June 25, 2021
      • Ramasamy Paulmurugan + 1 more
      • English
      • Hardback
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      • eBook
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      Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than Temozolomide, and specific strategies to reverse chemoresistance. Additionally, it encompasses information on how to mitigate chemoresistance by targeted enhancement of p53 function. This book is a valuable resource for cancer researchers, oncologists, neuro-oncologists and other members of the biomedical field. Glioblastoma (GBM) is the most invasive and malignant primary brain tumor in humans with poor survival after diagnosis, therefore it is imperative that molecular and cellular mechanisms behind therapy resistant GBM cells, as well as the therapeutic strategies available to counter the resistance are comprehensively understood.

    • Scientific Principles of Adipose Stem Cells

      • 1st Edition
      • August 19, 2021
      • Lauren Kokai + 2 more
      • English
      • Paperback
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      • eBook
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      Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, and data on the impact on human demographics (age, sex, BMI) on ASC phenotype. A section devoted to ASC biology, ASCs for stem cell therapy and regenerative medicine, and ASCs in tissue engineering applications are also included. The book is written for scientists and clinicians who are broadly familiar with stem cells and basic cell biology principles and those seeking advanced information on adipose stem cells.

    • Inflammation and Oral Cancer

      • 1st Edition
      • September 1, 2021
      • Hiroyuki Tomita
      • English
      • Paperback
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      • eBook
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      Inflammation and Oral Cancer: From Bench to Bedside discusses all aspects surrounding the relationship between inflammation and oral cancer, from basic science to the translational research that helps in the optimization of clinical management strategies. The book discusses topics such as chronic inflammation and cancer in oral cavity, the role of HPV in oral inflammation and cancer, rodent models of oral cancer, and epigenetics in oral inflammation and cancer. This is a valuable resource for cancer researchers, oncologists and members of biomedical field who are interested in learning more about the diverse aspects of inflammation and oral cancer. Inflammation in oral mucosa can remodel the topography of the overlying epithelium. If such inflammation is chronic, it can have fundamental clinical consequences, the principal of which can be premalignant lesions throughout the alimentary tract. Furthermore, mucosal inflammation, even if subtle, is the single most common pathway for oral cancer - therefore it is very important to understand these interactions in detail.

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