Biological Macromolecules
Bioactivity and Biomedical Applications
- 1st Edition - November 18, 2021
- Imprint: Academic Press
- Editors: Amit Kumar Nayak, Amal Kumar Dhara, Dilipkumar Pal
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 8 5 7 5 9 - 8
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 5 6 3 8 - 6
Biological Macromolecules: Bioactivity and Biomedical Applications presents a comprehensive study of biomacromolecules and their potential use in various biomedical applicati… Read more
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Request a sales quoteBiological Macromolecules: Bioactivity and Biomedical Applications presents a comprehensive study of biomacromolecules and their potential use in various biomedical applications. Consisting of four sections, the book begins with an overview of the key sources, properties and functions of biomacromolecules, covering the foundational knowledge required for study on the topic. It then progresses to a discussion of the various bioactive components of biomacromolecules. Individual chapters explore a range of potential bioactivities, considering the use of biomacromolecules as nutraceuticals, antioxidants, antimicrobials, anticancer agents, and antidiabetics, among others. The third section of the book focuses on specific applications of biomacromolecules, ranging from drug delivery and wound management to tissue engineering and enzyme immobilization. This focus on the various practical uses of biological macromolecules provide an interdisciplinary assessment of their function in practice. The final section explores the key challenges and future perspectives on biological macromolecules in biomedicine.
- Covers a variety of different biomacromolecules, including carbohydrates, lipids, proteins, and nucleic acids in plants, fungi, animals, and microbiological resources
- Discusses a range of applicable areas where biomacromolecules play a significant role, such as drug delivery, wound management, and regenerative medicine
- Includes a detailed overview of biomacromolecule bioactivity and properties
- Features chapters on research challenges, evolving applications, and future perspectives
Molecular biologists and biochemists actively involved with biological macromolecules; biotechnologists, chemical engineers, pharmaceutical scientists, biomedical scientists
- Cover image
- Title page
- Table of Contents
- Copyright
- List of contributors
- Preface
- Part I: Background
- Chapter 1. Biological macromolecules: sources, properties, and functions
- Abstract
- 1.1 Introduction
- 1.2 Carbohydrates
- 1.3 Lipids
- 1.4 Proteins
- 1.5 Nucleic acids
- 1.6 Conclusion
- References
- Chapter 2. Structure–activity relationship of biological macromolecules
- Abstract
- 2.1 Introduction
- 2.2 Enzymes as bioactive proteins
- 2.3 Chitosan as a bioactive polysaccharide
- 2.4 Conclusion
- References
- Chapter 3. The importance of biological macromolecules in biomedicine
- Abstract
- 3.1 Introduction
- 3.2 Biological macromolecules in biomedicine and therapies
- 3.3 Carbohydrates
- 3.4 Peptides
- 3.5 Proteins
- 3.6 Lipids
- 3.7 Nucleic acids and oligonucleotides
- 3.8 Synthesis of macromolecules
- 3.9 Biomedicine
- 3.10 Conclusions
- References
- Chapter 4. Modification techniques for carbohydrate macromolecules
- Abstract
- 4.1 Introduction
- 4.2 Cellulose
- 4.3 Hemicelluloses
- 4.4 Lignin
- 4.5 Chitin and chitosan
- 4.6 Modification of carbohydrate biological macromolecules
- References
- Part II: Bioactivity
- Chapter 5. Biological macromolecules as nutraceuticals
- Abstract
- 5.1 History of the applications of nutraceutical compounds in health care
- 5.2 Alkaloids
- 5.3 Phenolic compounds
- 5.4 Terpenes
- 5.5 Future views
- 5.6 Proteins and peptides with biological activity of medical interest
- 5.7 Nucleic acids and their nutraceutical properties used in biomedicine
- 5.8 Introduction of lipids
- 5.9 The potential use of bioactive lipids in cancer stem cells and coronavirus disease (COVID-19)
- 5.10 Carbohydrates as nutraceuticals
- 5.11 Credit
- References
- Chapter 6. Biological macromolecules as antioxidants
- Abstract
- 6.1 Introduction
- 6.2 Types and sources of biological macromolecules
- 6.3 Macromolecules as antioxidants
- 6.4 Applications
- 6.5 Limitations of biological macromolecules
- 6.6 Future trends
- References
- Chapter 7. Biological macromolecules as antimicrobial agents
- Abstract
- 7.1 Introduction
- 7.2 Classification of biological macromolecule
- 7.3 Antimicrobial activity of biological macromolecules
- 7.4 Antimicrobial activity of macromolecule composites
- 7.5 Nanotechnology based antimicrobial macromolecule
- 7.6 Applications
- 7.7 Conclusion
- References
- Chapter 8. Biological macromolecules from algae and their antimicrobial applications
- Abstract
- 8.1 Introduction
- 8.2 Bioactive macromolecules
- 8.3 Conclusion
- References
- Chapter 9. Biological macromolecules acting on central nervous system
- Abstract
- 9.1 Introduction
- 9.2 Conclusion
- References
- Chapter 10. Biological macromolecules as antidiabetic agents
- Abstract
- 10.1 Introduction
- 10.2 Types of biological macromolecules
- 10.3 Biological macromolecules
- 10.4 Advantages, limitations, and future perspectives
- 10.5 Conclusion
- References
- Chapter 11. Biological macromolecules as anticancer agents
- Abstract
- 11.1 Introduction
- 11.2 Biological macromolecules for cancer therapy
- 11.3 Conclusion
- References
- Chapter 12. Biological macromolecules as immunomodulators
- Abstract
- 12.1 Introduction
- 12.2 Immunomodulation
- 12.3 Immunomodulation, biomolecules, and applications
- 12.4 Polysaccharides
- 12.5 Lipids
- 12.6 Proteins
- Acknowledgments
- References
- Chapter 13. Biological macromolecules acting on gastrointestinal systems
- Abstract
- 13.1 Introduction
- 13.2 Role of carbohydrates in gastrointestinal system
- 13.3 Role of proteins in gastrointestinal system
- 13.4 Role of fatty acids in gastrointestinal system
- 13.5 Role of nucleic acids in gastrointestinal system
- 13.6 Conclusion
- References
- Chapter 14. Synthetic macromolecules with biological activity
- Abstract
- 14.1 Introduction
- 14.2 Synthetic macromolecules with antimicrobial activity
- 14.3 Synthetic macromolecules with antioxidant activity
- 14.4 Polymer sequestrants
- 14.5 Conclusions
- References
- Further reading
- Part III: Functional Applications
- Chapter 15. Biological macromolecules in drug delivery
- Abstract
- 15.1 Introduction
- 15.2 Drug delivery using various biological macromolecules
- 15.3 Conclusion
- References
- Chapter 16. Biological macromolecules in tissue engineering
- Abstract
- 16.1 Introduction
- 16.2 Bone tissue engineering
- 16.3 Biological macromolecules in bone tissue engineering
- 16.4 Conclusion
- Acknowledgment
- References
- Chapter 17. Biological macromolecules for drug delivery in tissue engineering
- Abstract
- 17.1 Introduction
- 17.2 Drug-loaded electrospun fibers used in tissue engineering applications and drug delivery
- 17.3 Drug-loaded injectable hydrogels used in tissue engineering applications and drug delivery
- 17.4 Conclusions
- References
- Chapter 18. Biological macromolecules for growth factor delivery
- Abstract
- 18.1 Introduction
- 18.2 Delivery systems for growth factors
- 18.3 Materials for delivery systems of growth factors
- 18.4 Biological macromolecules for delivery systems of growth factors
- References
- Chapter 19. Biological macromolecules for growth factor delivery in bone regeneration
- Abstract
- 19.1 Introduction
- 19.2 Bone regeneration
- 19.3 Growth factors in tissue and bone regeneration
- 19.4 Biomacromolecules as carriers of growth factors
- 19.5 Hydrogels and sponges
- 19.6 Scaffolds and fibers
- 19.7 Nanoparticles and nanoassemblies
- 19.8 Concluding remarks
- References
- Chapter 20. Biological macromolecules for nutrients delivery
- Abstract
- 20.1 Introduction
- 20.2 Nutrients
- 20.3 Biological macromolecules used for nutrients delivery
- 20.4 Molecular interactions that maintain the stability of biopolymer-based delivery systems
- 20.5 Retention and release mechanisms
- 20.6 Nutrient delivery systems based on biological macromolecules
- 20.7 Future trends
- References
- Chapter 21. Biological macromolecules for nucleic acid delivery
- Abstract
- 21.1 Introduction
- 21.2 Nucleic acids structure and functions
- 21.3 Biological macromolecules for nucleic acid delivery
- 21.4 Conclusions
- References
- Chapter 22. Biological macromolecules in cell encapsulation
- Abstract
- 22.1 Introduction
- 22.2 Biopolymers used for cell encapsulation in TE
- 22.3 Advantages, drawbacks, applications, forms and manufacturing methods
- 22.4 Conclusions
- Acknowledgment
- References
- Chapter 23. Biological macromolecules for enzyme immobilization
- Abstract
- 23.1 Introduction
- 23.2 Biological macromolecules for enzyme immobilization
- 23.3 Conclusions and future outlook
- Acknowledgment
- Conflicts of interest
- References
- Further reading
- Chapter 24. Carbohydrates mimetics: enzyme inhibitors and target molecules in several diseases
- Abstract
- 24.1 Introduction
- 24.2 Glycomimetics
- 24.3 Hybrid carbohydrates
- 24.4 Macromolecules
- 24.5 Conclusions
- References
- Part IV: Others
- Chapter 25. Current challenging issues of biological macromolecules in biomedicine
- Abstract
- 25.1 Introduction
- 25.2 Biological macromolecules
- 25.3 Macromolecules in biomedical applications
- 25.4 Macromolecules in targeted drug delivery
- 25.5 Biomaterials as targeted drug delivery
- 25.6 Macromolecules on tissue engineering
- 25.7 Conclusion
- References
- Chapter 26. Future perspectives of biological macromolecules in biomedicine
- Abstract
- 26.1 Bio-nanotechnology
- 26.2 Mitochondrial gene therapy
- 26.3 Crosstalk between chronobiology and cancer
- 26.4 Concluding remarks
- References
- Index
- Edition: 1
- Published: November 18, 2021
- No. of pages (Paperback): 672
- No. of pages (eBook): 672
- Imprint: Academic Press
- Language: English
- Paperback ISBN: 9780323857598
- eBook ISBN: 9780323856386
AN
Amit Kumar Nayak
Dr. Amit Kumar Nayak (MPharm, PhD) is working as a professor, at the Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha ‘O' Anusandhan (Deemed to be University), Odisha, India. He has earned his PhD from IFTM University, Moradabad, Uttar Pradesh, India. He has over 14 years of research experiences in the field of pharmaceutics, especially in the development and characterization of novel biopolymeric and nanostructured drug delivery systems. Till date, he has authored more than 138 research and review publications in various high-impact peer-reviewed journals and 135 book chapters. He has edited/authored 23 international books to his credit. Dr. Nayak has presented his research work at several conferences. He has received University Foundation Day Research Award, 2019 and 2022 by Biju Patnaik University of Technology, Odisha. Dr. Nayak is a life member of the Association of Pharmaceutical Teachers of India (APTI) and a registered pharmacist.
Affiliations and expertise
Professor, Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha, IndiaAD
Amal Kumar Dhara
Dr. Amal Kumar Dhara (MPharm, PhD) has over 20 years of teaching and research experience in the fields of Pharmacology and Toxicology, especially in the areas of neuropharmacology and anti-inflammatory, antiulcer, and free radical scavenging activities of indigenous Indian plants. He earned his PhD in Pharmaceutical Sciences from Jadavpur University, Kolkata, West Bengal, India. Currently, Dr. Dhara works as a Lecturer in Pharmacy (Associate Professor) at Contai Polytechnic, Purba Medinipur, West Bengal, India.
Affiliations and expertise
Department of Pharmacy, Contai Polytechnic, Government of West Bengal, Contai, Purba Medinipur, West Bengal, IndiaDP
Dilipkumar Pal
Dr. Dilipkumar Pal is an Associate Professor at the Department of Pharmaceutical Sciences, Guru Ghasidash Vishwavidyalaya, Bilaspur, India. He received his master and PhD degree from Jadavpur Universty, Kolkata, and performed post-doctoral research as Endeavour research fellow in University of Sydney, Australia. His research interests include phytochemical pharmacological evaluation of indigenous plants and natural biopolymers. He has published 177 full research papers in peer-reviewed national and international scientific journals, and contributed 115 abstracts in different national and international conferences. He has written one book and 68 book chapters and edited seven books published by reputed international publishers. Dr. Pal had received 13 national and international professional awards and has guided seven PhD and 39 master students for their dissertation thesis. He is the reviewer and Editorial Board member of 27 and 29 scientific journals, respectively. Dr Pal is the Editor-in-Chief of the research journal SPER Journal of Pharmaceutical and Biological Research.
Affiliations and expertise
Guru Ghasidash VishwavidyalayaRead Biological Macromolecules on ScienceDirect