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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Methods in Stem Cell Biology - Part B

      • 1st Edition
      • Volume 171
      • August 9, 2022
      • English
      • Hardback
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      • eBook
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      Methods in Cancer Stem Cell Biology: Part B, Volume 171 in the Methods in Cell Biology series highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Orthotopic brain tumor models derived from glioblastoma stem-like cells, RNA sequencing in hematopoietic stem cells, Generation of inducible pluripotent stem cells from human dermal fibroblasts, In vitro preparation of dental pulp stem cell grafts combined with biocompatible scaffolds for tissue engineering, Gene expression knockdown in chronic myeloid leukemia stem cells, Identification and isolation of slow-cycling GSCs, Assessment of CD133, EpCAM, and much more.

    • RAS: Past, Present, and Future

      • 1st Edition
      • Volume 153
      • January 29, 2022
      • English
      • Hardback
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      • eBook
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      Advances in Cancer Research, volume 153 provides a timely review of the biology, biochemistry, and current approaches to therapeutically target the RAS oncoprotein, the most frequently mutated oncogene family in human cancers. 2021 saw the approval of the first direct RAS inhibitor (sotorasib) for use in treating non-small cell lung cancers harboring KRAS(G12C) mutations. The successful approval and use of this drug highlights that the once “undruggable” RAS is indeed pharmacologically tractable. This volume provides an overview of efforts to develop additional approaches to therapeutically target oncogenic RAS. In addition, the reader will find excellent reviews on the history and research efforts to understand the biochemistry and oncogenic activity of RAS in human cancers.

    • Integrated Methods in Protein Biochemistry: Part A

      • 1st Edition
      • Volume 675
      • October 9, 2022
      • English
      • Hardback
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      • eBook
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      Integrated Methods in Protein Biochemistry: Part A, Volume 677, the latest release in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on topics such as DNA and protein engineering to create protein bioswitches with new functions, Interaction and cross-talk of prelamin A with integral membrane zinc metalloproteases, An experimental protocol to study lipid transfer proteins, Synthesis of small heat shock proteins, Druggable p-p interacting sites for Co-chaperone DNAJA1 and its partner proteins, An experimental protocol for glycoconjugate analysis, Methods for proximity-based biotinylation combined with Mass Spectrometry, and more. Additional chapters cover Synthetic antibody fragments as conformational sensors of protein activation and trafficking, Expression, purification, functional analysis and crystallization of Rag GTPase, Purification of bacterial transcription elongation complexes by photoreversible immobilization, Inhibition of c-Myc-MAX heterodimerization, Fluorogenic RNA aptamers to probe transcription by multi-subunit RNA polymerases, and much more.

    • Advances in Biomolecular EPR

      • 1st Edition
      • Volume 666
      • April 22, 2022
      • English
      • Hardback
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      • eBook
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      Advances in Biomolecular EPR, Volume 666 in the Methods of Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics including Magnetic Resonance Characterization of Physiologically Important Metal Ion Binding Sites in the Prion and Related Proteins, The catalytic role of metal-radical/protei... radicals in heme enzymes, Rigid Cu2+-based spin labels for the study of higher-order DNA G-quadruplex structures, Orthogonal spin labeling and membrane proteins: increasing the information content and going towards in cell applications, Spectroscopic investigation of mono- and di-Mn-containing centers in biochemistry with an emphasis on application of paramagnetic resonance techniques, and more. Additional chapters cover In Vivo pO2 Imaging of Tumors: Oxymetry with Very Low-Frequency Electron Paramagnetic Resonance, an Update, EPR contributions to understanding molybdenum-containin... enzymes, EPR spectroscopy of Type I reaction centers, Characterization of a substrate-derived radical in the NosN reaction during the biosynthesis of nosiheptide, and much more.

    • Helicase Enzymes Part B

      • 1st Edition
      • August 12, 2022
      • English
      • Hardback
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      • eBook
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      Methods in Enzymology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

    • One, No One, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease - Part B

      • 1st Edition
      • Volume 368
      • May 20, 2022
      • English
      • Hardback
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      • eBook
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      One, No One, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease - Part B, Volume 369 provides in-depth reviews on the last progresses on the role of macrophages in health and diseases, with a special focus on the role of macrophages during development. New chapters cover The role of salivary gland macrophages in infection, disease and repair, Reprogramming or replacing brain macrophages to treat neurodegenerative disease, Targeting macrophages for cancer immunotherapy, Heart Macrophages at steady-state and disease: simple bystanders or active players?, Macrophages in the liver, and Developmental programming of macrophages.

    • Disorders of Protein Synthesis

      • 1st Edition
      • Volume 132
      • September 7, 2022
      • Rossen Donev
      • English
      • Hardback
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      • eBook
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      Disorders of Protein Synthesis, Volume 132 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

    • DNA Damage and Double Strand Breaks

      • 1st Edition
      • Volume 51
      • October 19, 2022
      • English
      • Hardback
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      • eBook
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      DNA Damage and Double Strand Breaks, Volume 51 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters that provide an update on female and male genital schistosomiasis and a call to integrate efforts to escalate diagnosis, treatment and awareness in endemic and non-endemic settings, vertebrates as uninfected disseminators of helminth eggs and larvae, and combatting anthelmintic resistance in ruminants.

    • Immunotherapeutics

      • 1st Edition
      • Volume 129
      • March 11, 2022
      • Rossen Donev
      • English
      • Hardback
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      • eBook
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      Immunotherapeutics, Volume 129 in the Advances in Protein Chemistry and Structural Biology series highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Vaccines for the prophylaxis and treatment of HPV, Lung-targeted RNA-based therapeutics, Clostridium difficile: Current overview and future perspectives, Antivenoms for treatment of snake bites, Natural killer cell-based strategies for immunotherapy of cancer, Immunological insights of selectins in human disease mechanism, Current update, challenges, and future aspects of immunotherapeutics in non-small cell lung cancer, In silico interaction analysis of NEMO binding domain peptide on the NFkB protein, and much more.

    • Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications - Part A

      • 1st Edition
      • Volume 186
      • January 13, 2022
      • English
      • Hardback
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      • eBook
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      Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications, Volume 185, Part A represents the collation of chapters written by eminent scientists worldwide. Chapters in this updated release include An introduction to microfluidics and their applications, Design and fabrication of Micro/Nanofluidics devices and systems, Detection and separation of proteins using Micro/Nanofluidics devices, Micro/Nanofluidics devices for DNA/RNA detection and separation, Paper based microfluidics a forecast towards the most affordable and rapid point-of-care devices, Paper based micro/Nanofluidics devices for biomedical applications, Advances of Microfluidics Devices and their Applications in Personalized Medicine, and much more. Additional chapters cover Microfluidics for single cell analysis, Fluorescence Based Miniaturized Microfluidic and Nanofluidic Systems for Biomedical Applications, Active Matter Dynamics in Confined Microfluidic Environments, Challenges and opportunities in micro/nanofluidics and lab-on-a-chip, and Paper-microfluidic signal-enhanced immunoassays.

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